SGID Silkworm Genome Informatics Database
Gene
KWMTBOMO14080  Validated by peptides from experiments
Pre Gene Modal
BGIBMGA011218
Annotation
PREDICTED:_alpha-esterase_48_isoform_X1_[Bombyx_mori]
Location
Bomo_Chr23(-):17518789-17553037      View in EpiBrowser
Location in the cell
Cytoplasmic   Reliability : 2.433
 

Sequence

CDS
ATGATATCGGCCGTGAACGAATTCCTAGATGATCTTCGTGGTGGCAGGATGTCCGAGTCGCCTCTAGTCACGGTGGAGCAAGGGCAGCTCCAGGGACGGATCGTAAACAGCCCGTCCGGGAAGGCCTTCTACAGTTTCCAAGGAATACCATATGCGAAACCCCCATTGGGGTCTTTGCGATTTAAGGCACCTAAACCAGCGGAAACTTGGGAAGGAATCCGAGATGCCACAGCAGAGGGAAACATCGCTCCGCAAATAGACACATCGCTCACGAAAACATATACTGGCGATGAAAACTGCCTATATTTAAACGTATATACCCCACATATCGCCGGAAACCTACCCGTAATGATTTGGATCCATGGTGGGGCCTTCAAATGGGGCTCAGGCAATGAAACCCTATATGGCCCCGATTATCTGGTTGAGAAAGACGTTGTCGTTGTTACCCTCAACTACAGATGTGGACCTTTGGGTTTCTTATGCCTGAATACCCCTGAAGTGCCAGGAAACGCTGGACTCAAAGACGTGGTCCAAGCACTGAGGTGGCTAAAACAGAATATAAAGAGTTTCGGTGGAGATCCTGATAATTTCACTGTGTTCGGTCAAAGCGCCGGTGGGGCCATTGTAACGATACTAACTGCTAGTCCACTGTCTAAAAACATGATTAATAAGGCTATTGTACAATCCGGTACCGGTATATCAAAATGGGCTGTACAAAATGAGCCATTGACCTGTGCCAAGGCTTTGGCAAGTCATTTAGGTTGCGAAGCTGACAACGTTGACGAAGTTCTAGAGTTCTTGAACACAGTCACGGCTAAAGAACTTGTCGAGGCAACGGAAATCGTTAATTCCTTCGATAGTTTAGTTGTCGATCAGAATAACTTTTTCTCTGTTGTCGTCGAGAAAGAATTCCCGGGTGTCGAAGCTGTACTGACGGAGCCTCTTTTAGATTTCTTAACGTCAGGACGTACAGCCGAAATTCCTATAATGATCGGCTCGACAACGCTCGAACTTCTAACTAACCTAAGACCGAGTGATTTGCAAATGTTTATCCCTTCAGATTTGAATATTGAAAAGGATTCAGACGAGTCCTTAGCCATTGCTGAAAATTTAAAAGGCTTATATTTCACAAGCGATACAGAAGAAAACAAAGCCGAAGGTCTAAACAGGCTCCATTCTGATTTATTACTGAATATAAACATCAATAGATACATCAAATATTTAGTTCAAAATTCAAATCAGCCAATATATTTTTATAAATTTGATTACGTTGGCCAATTCAACTTCGCCCATAAGTCATTTTTTGATACAGAACTAAAATACGCCCTGCACATGGACGATTTAGGGTATTTGTTCAAAAATGACTTCCAGAAAGACGTGGATGACCCAAGCCCTCAAGATGTTAAGATGAGGGAAAGAATGGTCAGACTTTGGACTAATTTCGCCAAATTTGGAAATCCCACCCCAGAAGAAAACCACTATCTCCCAACGAAATGGCTACCGGTTACCAATGATACTCTCTACTACCTAAACTTGGGTCAAGAGCTGAATCTTCTCCAAAACCCTGACGAGGAGATAATGAAATTCTGGGAAGATTTATACAGTAAACACTTCAAAATTTGGGAGCATACTAAAATAAATACCATCGAGCCACCCAGGAAACTTGTCTATCCTGATAACGAAGCTACTGAAGAACAAGCTTCCATTGATGACGGACAACCTAGCCTTGAAGAAAAAGTCGTTTTTGAAGAAATAGTGCCTATCAGTTCGGTACTAAACCCACCAGTTAACGGTGATGCTAAATCGAACGCAGATTTTAAGCCGAAGATTTCGAATGAAATTAAAATGGCTCAAACTTCTGCACCTAAAGACGTCGTGAGAGCCAGCGACCCGCCCGAAGACGACCTACCAAAGAACATAGGGGCCCCACAACCTCCAGAACCCTGGGACGGCATCAGGGATGCCACGGCGGAAGGGAACGTGTGTGCTCAAATCGATCCGGTCTTCGCGAAATCCTATGTCGGCGATGAAAACTGCTTGTTCCTAAATGTGTACACCCCTAGCACTGATGGAGCATTCCTCCCGGTCATGATTTGGATCCACGGTGGTGGGTTCAAGTGGGGATCCGGCAATACCAACTTGTATGGACCAGATTTTCTAGTTGACAGAGATGTCGTGGTGGTGACTATCAATTATAGATGTGGTGCTTTAGGGTTCTTAAGTCTGAACACGCCTGAAGTCCCAGGGAATGCTGGGATCAAAGATATAGTTCAAGCAATTAGATGGGTGAAAGATAATATCCATCACTTCGGTGGTAATGCCGGTAATTTGACAATATTTGGTGAAAGCGCGGGCGCGCGTGCGGTTTCATTGCTGACAGCTAGTCCGTTAACCAAAAATTTAATCAGCAAAGCTATAATCCAATCTGGAAACGCATTGTCTTCTAGAGCTTTTCAAAGAGACCCCTTACAAAGTGCTAAAGCTTTAGCCAGGAGTTTGGGCTGTGAAGCAGAAGACGTTGATGAAATTCTAGAGTTTTTAATCGCGACTCCAGCCAAAGACTTGGTTGAGGCAGACGAGAAGTTGAATTCTTTGCAGAAAGTTCTAGAAACGAGTAATAATTTGTTTGGGCTGGTAATCGAGAAGGAGTTTCCAGGAGTCGAAGCTGTCATCAGTGAGCCTTTCATTAACATACTAACATCAGGTAGAACAGCCAACATCCCAATACTAGTTGGAACTACGTCATTAGAGTACGCCTGCGAGAGAAAGACTGATGATCTTCAAGAGTTGATACCAGCTGACCTGAACATAGACAGAAACTCAGAAGAAGCCTTGGCAATCGTAGAAGAAATAAAGAAATTGTATTTCAAAGGGAACCACACAGGAGTGGAGAGTCTACCAGAATACTTCCATCTCCTATCAGACAAGTTGATCAATTTGGACACGCATCGATACATAAAATATTTGCTCCAAGTTACGAACCGTCCAATTTATTACTATAGATTTGATTATGTGGGCGAATTGAATATCGCCCAGAAGATCTTCTTTAGTCTTGGACTGAAGTACGCTATGCACATGGACGAGCTGGGCTATCTGTTCAAGAATGACTTCCAGAAAGACGTGGAGCCGACTCCTGAAGATATCAAGATGCGTGAGAGGATTGTCAGGCTCTGGACTAATTTCGCTAAATCTGGGAACCCGATACCGGACGAAAACCACTATTTGAACACCAACTGGCTACCGGTAACAAACGACAATTTATACTGTCTAAATCTAAATTCAGAATTAACTTTAATCTCAAACCCGGACCAAGAGAAGATGGACTTTTGGGAGAAAATCTACGACAAACACTACAGAATCTGGGATGAAACGACCAACCAGTCTAAAAACGAACCACAAATCGATACATTCAAAAAAGAACCAGAAATCGATACATACCAAAATGAATCAGAAATCGATACATGCAAAAAAGAAACAGAAATCGATACATACAAAAATGAACCAGAAATCGATGCGCCCAAACATGAACCGGAAATAGTGTCCGTTATCGAGACAGTGGTCATAACCCAAGTCATGAACAAAGAGACCAGCGTTTCCGAAGAGAGGACAGAAGTCGTGAGTGACTCTGACCAAATCGACAGAGCCGAAGTTGAAACGCAAATCACAACTACCACACTCCTTGAAAACAACGATGGCTCCCAAACTTTGATAGTCACAGAGAAAACTGAGACCCCCGAACAAGCACCGAGCGTCAAAGAAATGATACTGGAATTCAGTGAACCGGCCCAACTAGAGTCGAATGAACACAAACCGGTCAATGACCACATAAACACTAACGGAGTCGACAAGAAAGCCAGGACTTCGAACGAAATCAAAATGGTGCATAACAGCAACGGTGCTCCAAAGGACGTGATCAGAGCTAATGATCCGCCCGAAGACGATCTACCCAAGAACATAGGAGTGAATAAATTCGTCAGTTTCTTCGAATCGCTAGGCGGAAAGAAGTAA
Protein
MISAVNEFLDDLRGGRMSESPLVTVEQGQLQGRIVNSPSGKAFYSFQGIPYAKPPLGSLRFKAPKPAETWEGIRDATAEGNIAPQIDTSLTKTYTGDENCLYLNVYTPHIAGNLPVMIWIHGGAFKWGSGNETLYGPDYLVEKDVVVVTLNYRCGPLGFLCLNTPEVPGNAGLKDVVQALRWLKQNIKSFGGDPDNFTVFGQSAGGAIVTILTASPLSKNMINKAIVQSGTGISKWAVQNEPLTCAKALASHLGCEADNVDEVLEFLNTVTAKELVEATEIVNSFDSLVVDQNNFFSVVVEKEFPGVEAVLTEPLLDFLTSGRTAEIPIMIGSTTLELLTNLRPSDLQMFIPSDLNIEKDSDESLAIAENLKGLYFTSDTEENKAEGLNRLHSDLLLNININRYIKYLVQNSNQPIYFYKFDYVGQFNFAHKSFFDTELKYALHMDDLGYLFKNDFQKDVDDPSPQDVKMRERMVRLWTNFAKFGNPTPEENHYLPTKWLPVTNDTLYYLNLGQELNLLQNPDEEIMKFWEDLYSKHFKIWEHTKINTIEPPRKLVYPDNEATEEQASIDDGQPSLEEKVVFEEIVPISSVLNPPVNGDAKSNADFKPKISNEIKMAQTSAPKDVVRASDPPEDDLPKNIGAPQPPEPWDGIRDATAEGNVCAQIDPVFAKSYVGDENCLFLNVYTPSTDGAFLPVMIWIHGGGFKWGSGNTNLYGPDFLVDRDVVVVTINYRCGALGFLSLNTPEVPGNAGIKDIVQAIRWVKDNIHHFGGNAGNLTIFGESAGARAVSLLTASPLTKNLISKAIIQSGNALSSRAFQRDPLQSAKALARSLGCEAEDVDEILEFLIATPAKDLVEADEKLNSLQKVLETSNNLFGLVIEKEFPGVEAVISEPFINILTSGRTANIPILVGTTSLEYACERKTDDLQELIPADLNIDRNSEEALAIVEEIKKLYFKGNHTGVESLPEYFHLLSDKLINLDTHRYIKYLLQVTNRPIYYYRFDYVGELNIAQKIFFSLGLKYAMHMDELGYLFKNDFQKDVEPTPEDIKMRERIVRLWTNFAKSGNPIPDENHYLNTNWLPVTNDNLYCLNLNSELTLISNPDQEKMDFWEKIYDKHYRIWDETTNQSKNEPQIDTFKKEPEIDTYQNESEIDTCKKETEIDTYKNEPEIDAPKHEPEIVSVIETVVITQVMNKETSVSEERTEVVSDSDQIDRAEVETQITTTTLLENNDGSQTLIVTEKTETPEQAPSVKEMILEFSEPAQLESNEHKPVNDHINTNGVDKKARTSNEIKMVHNSNGAPKDVIRANDPPEDDLPKNIGVNKFVSFFESLGGKK

Summary

Similarity
Belongs to the type-B carboxylesterase/lipase family.
Uniprot
H9JNW4   A0A1W4XHU4   A0A194Q3V9   A0A139WDB1   A0A232EEQ8   A0A0L7L5N8   + More
Pubmed
19121390    26354079    18362917    19820115    28648823    26227816    + More
EMBL
BABH01009833    BABH01009834    KQ459586    KPI98095.1    KQ971360    KYB25958.1    + More
NNAY01005233    OXU16849.1    JTDY01002769    KOB70767.1   
Proteomes
UP000005204    UP000192223    UP000053268    UP000007266    UP000215335    UP000037510    + More
PRIDE
H9JNW4   
Pfam
PF00135   COesterase
Interpro
IPR002018   CarbesteraseB        + More
IPR019826   Carboxylesterase_B_AS       
IPR029058   AB_hydrolase       
IPR019819   Carboxylesterase_B_CS       
SUPFAM
SSF53474   SSF53474       
Gene 3D
3.40.50.1820    
ProteinModelPortal
H9JNW4   A0A1W4XHU4   A0A194Q3V9   A0A139WDB1   A0A232EEQ8   A0A0L7L5N8   + More
PDB
5IVK     E-value=1.38105e-72,     Score=699

Ontologies

KEGG
733006    no KO assigned | (RefSeq) ae48, Bmae48, Bmcce-5al, Bmcce-5as1, Bmcce-5as2, Bmcce-5b, cce-5b, jhe-lp5
GO
GO:0016787   GO:0005615   GO:0052689  

Topology

Length:
1335
Number of predicted TMHs:
0
Exp number of AAs in TMHs:
0.43273
Exp number, first 60 AAs:
0.00019
Total prob of N-in:
0.01965
outside
1  -  1335
 
 

Population Genetic Test Statistics

Pi
183.282689
Theta
18.939346
Tajima's D
0.385419
CLR
1.136415
CSRT
0.484875756212189
Interpretation
Uncertain
Peptides ×
Source Sequence Identity Evalue
26822097 AVSIITASPITK 95.65 2e-10
25044914 DNIFQCINK 95.65 2e-10
28556443 SESPLVTVEQGQLQGR 100.00 1e-08
28556443 VVFEEIVPISSVLNPPVNGDAK 100.00 2e-07
28556443 VVFEEIVPISSVLNPPVNGDAK 100.00 2e-07
28556443 VVFEEIVPISSVLNPPVNGDAK 100.00 2e-07
28556443 SESPLVTVEQGQLQGR 100.00 2e-07
28556443 VVFEEIVPISSVLNPPVNGDAK 100.00 2e-07
28556443 VVFEEIVPISSVLNPPVNGDAK 100.00 2e-07
28556443 VLETSNNLFGLVIEK 100.00 2e-07
28556443 VLETSNNLFGLVIEK 100.00 2e-07
25044914 EFNQVIK 95.24 5e-07
28556443 SESPLVTVEQGQLQGR 100.00 1e-06
28556443 NSEEALAIVEEIKK 100.00 1e-06
28556443 GLYFTSDTEENKAEGLNR 100.00 1e-06
28556443 GLYFTSDTEENKAEGLNR 100.00 1e-06
28556443 WGSGNETLYGPDYLVEK 100.00 2e-06
28556443 WGSGNETLYGPDYLVEK 100.00 2e-06
28556443 WGSGNETLYGPDYLVEK 100.00 2e-05
28556443 WGSGNETLYGPDYLVEK 100.00 2e-05
28556443 WAVQNEPLTCAK 100.00 2e-05
28556443 WGSGNETLYGPDYLVEK 100.00 2e-05
28556443 VVFEEIVPISSVLNPPVNGDAK 100.00 2e-05
28556443 WAVQNEPLTCAK 100.00 2e-05
28556443 GLYFTSDTEENKAEGLNR 100.00 2e-05
28556443 FWEDLYSK 100.00 2e-05
28556443 FWEDLYSK 100.00 2e-05
28556443 FDYVGQFNFAHK 100.00 2e-05
28556443 DATAEGNIAPQIDTSLTK 100.00 7e-05
28556443 ASDPPEDDLPK 100.00 7e-05
28556443 AVSLLTASPLTK 100.00 7e-05
28556443 AVSLLTASPLTK 100.00 7e-05
28556443 MSESPLVTVEQGQLQGR 100.00 7e-05
28556443 LYFTSDTEENKAEGLNR 100.00 7e-05
28556443 LYFTSDTEENKAEGLNR 100.00 7e-05
28556443 HEPEIVSVIETVVITQVMNK 100.00 7e-05
28556443 LYFTSDTEENKAEGLNR 100.00 1e-04
28556443 GLYFTSDTEENKAEGLNR 100.00 1e-04
28556443 IWDETTNQSK 100.00 1e-04
28556443 FVSFFESLGGK 100.00 1e-04
28556443 FDYVGQFNFAHK 100.00 4e-04
28556443 ANDPPEDDLPK 100.00 4e-04
28556443 SAGGAIVTILTASPLSK 100.00 5e-04
28556443 SAGGAIVTILTASPLSK 100.00 5e-04
28556443 SAGGAIVTILTASPLSK 100.00 5e-04
28556443 MSESPLVTVEQGQLQGR 100.00 5e-04
28556443 SAGGAIVTILTASPLSK 100.00 5e-04
28556443 SAGGAIVTILTASPLSK 100.00 5e-04
28556443 NSEEALAIVEEIKK 100.00 5e-04
28556443 ASDPPEDDLPK 100.00 5e-04
28556443 SESPLVTVEQGQLQGR 100.00 7e-04
28556443 SDLQMFIPSDLNIEK 100.00 7e-04
28556443 SAGGAIVTILTASPLSK 100.00 7e-04
28556443 NEPQIDTFK 100.00 7e-04
28556443 YALHMDDLGYLFK 100.00 0.003
28556443 FWEDLYSK 100.00 0.003
28556443 YALHMDDLGYLFK 100.00 0.003
28556443 YALHMDDLGYLFK 100.00 0.003
28556443 YALHMDDLGYLFK 100.00 0.004
28556443 WGSGNETLYGPDYLVEK 100.00 0.004
28556443 WGSGNTNLYGPDFLVDR 100.00 0.004
28556443 WGSGNTNLYGPDFLVDR 100.00 0.004
28556443 SAGGAIVTILTASPLSK 100.00 0.004
28556443 LYFTSDTEENKAEGLNR 100.00 0.004
26822097 FWEDIYSK 100.00 0.009
28556443 FDYVGQFNFAHK 100.00 0.009
28556443 DVVQALR 100.00 0.009
28556443 DATAEGNIAPQIDTSLTK 100.00 0.009
28556443 DATAEGNIAPQIDTSLTK 100.00 0.009
26822097 FVNFYESIGGK 100.00 0.010
26280517 FIYSQIR 100.00 0.010
25044914 FIYVTDVGQYTHFMTIDACAR 100.00 0.010
28467696 FKAPEPPEPWDGIR 100.00 0.010
26822097 FKAPQPPEPWDGIR 100.00 0.014
26280517 APNVVSSNPIDNIDFSSQAFK 100.00 0.014
25044914 APQETYADIGGIDTQIQEIK 100.00 0.014
28556443 APQPPEPWDGIR 100.00 0.014
28556443 ANDPPEDDLPK 100.00 0.014
28556443 AIIQSGNALSSR 100.00 0.014
28556443 VLETSNNLFGLVIEK 100.00 0.015
28556443 TETPEQAPSVK 100.00 0.015
28556443 TEVVSDSDQIDR 100.00 0.015
28556443 VVFEEIVPISSVLNPPVNGDAK 100.00 0.018
28556443 VVFEEIVPISSVLNPPVNGDAK 100.00 0.018
Copyright@ 2018-2023    Any Comments and suggestions mail to:zhuzl@cqu.edu.cn   渝ICP备19006517号

渝公网安备 50010602502065号