Gene

KWMTBOMO14074  Validated by peptides from experiments

Pre Gene Modal

BGIBMGA011222

Annotation

PREDICTED:_acetyl-CoA_carboxylase_isoform_X1_[Bombyx_mori]

Location

Bomo_Chr23(-):17317808-17387731      View in EpiBrowser

Location in the cell

Cytoplasmic   Reliability : 2.446

CDS

ATGGCGGACGATTCCGTCCAATTACCACAGGAGCAGCGTTCGTCGAGCGAGAGCGATAATTTTGAAAAAATCGACTCCGATGAAGGACGAAATGTAGAGCCTACATTTATTGTCGGCGATGAATCCGATCCGGGACTGGACGACGGGCCGGCCCACGAGGGGAGAGACTTATTCCCCAACGCCCCTCCAGCGAACATCAGGAGGATGTTGACTCCAGCTCAGCAGCTAGCCTTGGCCGAGAAGAGGAGTCGACTAAGGCCGTCTATGTCCCAAGGAACAGTGGTGCACAGTCAGCGTTTCCAAGAAAAGGATTTTACAGTTGCCACTCCAGAAGAGTTTGTGAGACGGTTCCAGGGTACGAAGCCAATAAATAAAGTATTGATAGCTAATAACGGTATTGGTGCTGTAAAATGCATGCGTTCAATTCGAAGATGGTCCTACGAGATGTTCAAGAACGAACGGGCTGTGAGATTTGTGGTTATGGTGACCCCGGAAGATCTGAAAGCAAATGCAGAATATATAAAGATGGCTGATCATTATGTGCCAGTGCCTGGTGGATCGAATAATAACAATTATGCCAATGTGGAGCTTATTGTTGATATAGCAGTTAGAACGCAAGTTCAGGCCGTATGGGCTGGGTGGGGTCACGCTTCCGAGAACCCCAAGTTGCCGGAGCTGTTGCACCGAGCCGGGGTTGTGTTCATAGGCCCCCCGGAGAAGGCCATGTGGGCGCTCGGAGACAAAATCGCATCATCCATTGTGGCTCAGACTGCGGACATACCTACCCTACCTTGGAGCGGAAGCAAACTGAAGGCCGAATACAATTCGAAGAAGATAAAGATATCATCGGAGCTGTTCTCGAAGGGCTGCGTGTCCTCACCGGAGCACGGGCTGCAGGCTGCACAGAAAATTGGATTCCCCGTTATGATCAAGGCGTCGGAAGGCGGCGGCGGCAAGGGTATAAGGAAAGTCGAGAATCCGGATGACTTCAACAACATGTTTAGACAGGTCCAAGCCGAGGTCCCGGGCTCCCCTATATTCGTGATGAAGCTCGCGAAGTCCGCCCGCCACTTGGAGGTGCAGCTCCTCGCAGACCAGTACGGTAACGCGATATCGCTCTTCGGGCGCGACTGCTCCATCCAGCGTCGCCATCAGAAGATCATCGAGGAAGCACCGGCCGCCGTCGCGAAGCCTGATGTCTTCATCGAGATGGAGAAGGCCGCGGTGCGTCTGGCCAAGATGGTGGGCTACGTTAGCGCGGGAACAGTGGAATACCTGTACGATCCCTCGAGCGGCTCCTACTACTTCCTAGAGCTGAACCCTCGACTCCAGGTGGAGCATCCCTGCACAGAGATGGTGGCGGACGTGAATCTACCGGCCGCACAACTTCAGATTGCTATGGGTCTCCCTCTGTATCACATAAAAGATATACGTCTTCTATACGGAGAGTCGCCGTGGGGCATGACCCAGATCGATTTTGACGAGCCGAAGCAGCGACCCTCGCCCTGGGGCCACGTCATCGCCGCCAGGATCACCTCGGAAAATCCGGACGAAGGTTTCAAGCCTTCTTCCGGAACGGTCCAGGAGCTGAACTTCAGGTCCTCGAAGAACGTGTGGGGCTACTTCAGCGTGGCGGCGTCCGGCGGCCTGCACGAGTTCGCGGACTCGCAGTTCGGACACTGCTTCTCCTGGGGCGAGACCCGGGAGCAGGCCAGAGAAAACCTGGTGATAGCCCTCAAGGAGCTGAGCATACGGGGCGACTTCCGAACGACCGTGGAGTACCTCATCACATTGCTGGAGACGACCTCCTTCCAGGAGAACAACATCGACACCAGCTGGCTGGACGCTCTTATTGCGGAGAGGATGCAATCGGAGAAGCCGGACATCATGCTGGGCGTCATATGCGGCTCGATTCTGATCGCCGACAGCATCATCACGGCCAACTTCCAGGAGTTCAAGAGCGCGCTCGAGAAAGGTCAGATCCAAGGGTCGAGCCAGCTGTCGAACACGGTGGAGGTGGAGCTCATCCACAGCGGCCACAAGTACAAGGTGTCGGCGACCAAGTCCGGCCTTACGTCCTACTTCCTGGCCATGAACGGCAGCTTCAAGGAGCTGGAGGTGCACAAGCTGACCGACGGCGGTACCCTCTTATCGGTGGACGGCGCCTCCTTCACGACCTACTTGAAAGACGAAGTTGACAAATACAGGATAGTCATAGGAAACCAGACGGTGGTCTTCGAGAAGGAGAAGGACCCTTCGAGTCTGAGGGCCCCTTCAGCGGGGAAGCTGATCAACACGCTGGTGGAAGACGGAGGGCACGTCGACAAGGGACAGCCCTACGCTGAGATCGAGGTGATGAAAATGGTGATGACGCTGTCCGCCCCGGAATCCGGCAAGGTCACGTGGAATCTGCGGCCCGGAGCGGTCCTGGACATGGGCTCCCTGATCGGGACTCTGGGTAGGTGGGGGCAGCCGGGGGACGCGGCCACGCCAACGGTTTCGTCCGGACTGGAGATCATGAGACATCCGCCTCAAGTCTCAAGGTTGTCCACAGACTGTGGTAACCATTAA

Protein

MADDSVQLPQEQRSSSESDNFEKIDSDEGRNVEPTFIVGDESDPGLDDGPAHEGRDLFPNAPPANIRRMLTPAQQLALAEKRSRLRPSMSQGTVVHSQRFQEKDFTVATPEEFVRRFQGTKPINKVLIANNGIGAVKCMRSIRRWSYEMFKNERAVRFVVMVTPEDLKANAEYIKMADHYVPVPGGSNNNNYANVELIVDIAVRTQVQAVWAGWGHASENPKLPELLHRAGVVFIGPPEKAMWALGDKIASSIVAQTADIPTLPWSGSKLKAEYNSKKIKISSELFSKGCVSSPEHGLQAAQKIGFPVMIKASEGGGGKGIRKVENPDDFNNMFRQVQAEVPGSPIFVMKLAKSARHLEVQLLADQYGNAISLFGRDCSIQRRHQKIIEEAPAAVAKPDVFIEMEKAAVRLAKMVGYVSAGTVEYLYDPSSGSYYFLELNPRLQVEHPCTEMVADVNLPAAQLQIAMGLPLYHIKDIRLLYGESPWGMTQIDFDEPKQRPSPWGHVIAARITSENPDEGFKPSSGTVQELNFRSSKNVWGYFSVAASGGLHEFADSQFGHCFSWGETREQARENLVIALKELSIRGDFRTTVEYLITLLETTSFQENNIDTSWLDALIAERMQSEKPDIMLGVICGSILIADSIITANFQEFKSALEKGQIQGSSQLSNTVEVELIHSGHKYKVSATKSGLTSYFLAMNGSFKELEVHKLTDGGTLLSVDGASFTTYLKDEVDKYRIVIGNQTVVFEKEKDPSSLRAPSAGKLINTLVEDGGHVDKGQPYAEIEVMKMVMTLSAPESGKVTWNLRPGAVLDMGSLIGTLGRWGQPGDAATPTVSSGLEIMRHPPQVSRLSTDCGNH

Cofactor

biotin

Uniprot

A0A1V0M8C1   A0A0P0E5H9   H9JNW8   A0A2A4JQ91   A0A2A4JRH1   A0A0U3ATI3   + More
A0A068FK83   A0A2H1VWY0   A0A1W4XJA7   A0A1W5YLK9   A0A1Y1NDF1   D2A5X8   A0A0P4VXP9   A0A1Y1NG63   A0A0A9YFN2   A0A0A9Y5I5   A0A1W4X8U7   A0A1W4XJ22   A0A1W4X8M9   A0A224XHG0   A0A1B6DY08   A0A1B6CV39   A0A1B6M3V6   A0A1B6FL65   A0A1L8E0J6   A0A1B6LC21   A0A1L8E123   A0A1B6EF06   A0A1B6DHE3   A0A0R1DTL4   A0A0R1DM72   A0A0R1DLY0   A0A336MKR9   W4VRL7   A0A0P8XR56   B3MGC4   A0A0R1DUE2   A0A336ME20   Q7PQ11   A0A1Y9GKD4   A0A2M4CME3   A0A182LBJ6   A0A1Y9GLJ0   A0A1Y9GLJ1   A0A182V1C3   A0A2M4CMG2   A0A2M4CMA2   A0A1Y9H2E2   A0A2M4CMD9   A0A0Q5WL21   A0A0Q5WIM4   A0A0Q5WL54   A0A0J9R7W5   B4HRH5   A0A0Q5WP93   Q7JV23   A0A1I8MTZ7   A0A1I8MU01   A0A1Y9H1X3   A1Z784   A0A1Y9H1X8   A0A0J9TVV5   A0A0J9R7N5   A0A0J9R903   A0A2M3ZF48   T1PCN5   A0A084W2B0   A0A1W4VYW2   A0A0M4EUE5   B4MPP4   A0A3L8DPH9   A0A158NHP1   A0A1W4WAM9   A0A0R3NM35   A0A026WBM2   W8B0Q2   A0A0R3NLY6   A0A0R3NUF3   W8AF13   A0A1B6D1J6   A0A0Q9WGB0   A0A0Q9WG93   A0A0Q9W4U4   A0A0A9Y9M3   A0A195E2E3   A0A0A1WQB2   A0A1B0CTV1   T1ICG7   A0A195D4D1   U4UM60   F4WVP2   A0A195FW55   A0A151XFJ0   N6U7G4   Q176P0   A0A3B0J262   A0A1B6L389   A0A0G3YJ61   A0A336MSU0   A0A336KN71  

Pubmed

28349297    26445454    19121390    26385554    28004739    18362917    + More
19820115    27129103    25401762    17994087    17550304    12364791    14747013    17210077    20966253    18057021    22936249    10731132    12537568    12537572    12537573    12537574    16110336    17569856    17569867    26109357    26109356    25315136    24438588    30249741    21347285    15632085    24508170    24495485    25830018    23537049    21719571    17510324    25702953   

EMBL

KU755518    ARD71228.1    KT261731    ALJ30271.1    BABH01009813    BABH01009814    + More
BABH01009815    NWSH01000786    PCG74207.1    PCG74204.1    KR140280    ALS92678.1    KJ622074    AID66639.1    ODYU01004635    SOQ44714.1    KX147663    ARI45067.1    GEZM01005808    JAV95901.1    KQ971345    EFA05436.2    GDKW01001157    JAI55438.1    GEZM01005809    JAV95900.1    GBHO01015291    GBHO01015289    GBHO01015287    GBRD01015639    GBRD01015638    JAG28313.1    JAG28315.1    JAG28317.1    JAG50187.1    GBHO01015292    GBHO01015286    GBHO01015282    JAG28312.1    JAG28318.1    JAG28322.1    GFTR01008955    JAW07471.1    GEDC01006738    JAS30560.1    GEDC01019899    JAS17399.1    GEBQ01009397    JAT30580.1    GECZ01018837    JAS50932.1    GFDF01001890    JAV12194.1    GEBQ01018767    JAT21210.1    GFDF01001889    JAV12195.1    GEDC01000781    JAS36517.1    GEDC01012204    JAS25094.1    CM000157    KRJ98339.1    KRJ98344.1    KRJ98343.1    UFQS01000700    UFQT01000700    SSX06284.1    SSX26638.1    GANO01001823    JAB58048.1    CH902619    KPU77051.1    EDV37827.2    KRJ98340.1    KRJ98342.1    SSX06283.1    SSX26637.1    AAAB01008900    EAA09449.5    EDO64101.1    APCN01002864    GGFL01002257    MBW66435.1    GGFL01002277    MBW66455.1    GGFL01002278    MBW66456.1    GGFL01002275    MBW66453.1    CH954177    KQS70907.1    KQS70901.1    KQS70904.1    KQS70905.1    CM002911    KMY92156.1    CH480816    EDW46857.1    KQS70903.1    KQS70906.1    AE013599    AY119502    AAF59156.2    AAM50156.1    ABV53726.1    AHN55975.1    AHN55976.1    AAF59155.2    KMY92151.1    KMY92155.1    KMY92152.1    KMY92157.1    KMY92154.1    GGFM01006425    MBW27176.1    KA646501    AFP61130.1    ATLV01019578    ATLV01019579    ATLV01019580    ATLV01019581    ATLV01019582    ATLV01019583    ATLV01019584    ATLV01019585    KE525275    KFB44354.1    CP012524    ALC41032.1    CH963849    EDW74083.1    QOIP01000005    RLU22271.1    ADTU01015825    ADTU01015826    CM000071    KRT01975.1    KK107293    EZA53363.1    GAMC01019734    JAB86821.1    KRT01976.1    KRT01974.1    GAMC01019735    JAB86820.1    GEDC01017744    JAS19554.1    CH940648    KRF80078.1    KRF80075.1    KRF80076.1    GBHO01015290    GBHO01015283    GBHO01000038    JAG28314.1    JAG28321.1    JAG43566.1    KQ979763    KYN19246.1    GBXI01013501    JAD00791.1    AJWK01028013    AJWK01028014    AJWK01028015    ACPB03025489    KQ976870    KYN07737.1    KB632409    ERL95164.1    GL888393    EGI61712.1    KQ981208    KYN44890.1    KQ982194    KYQ59050.1    APGK01036619    APGK01036620    KB740941    ENN77580.1    CH477385    EAT42106.1    OUUW01000001    SPP75175.1    GEBQ01021847    JAT18130.1    KM507094    AKM28418.1    UFQS01002460    UFQT01002460    SSX14095.1    SSX33512.1    SSX06286.1    SSX26640.1   

Proteomes

UP000005204    UP000218220    UP000192223    UP000007266    UP000002282    UP000007801    + More
UP000007062    UP000075840    UP000075882    UP000075903    UP000075884    UP000008711    UP000001292    UP000000803    UP000095301    UP000030765    UP000192221    UP000092553    UP000007798    UP000279307    UP000005205    UP000001819    UP000053097    UP000008792    UP000078492    UP000092461    UP000015103    UP000078542    UP000030742    UP000007755    UP000078541    UP000075809    UP000019118    UP000008820    UP000268350   

PRIDE

H9JNW8    Q7JV23    A1Z784   

Pfam

PF02785   Biotin_carb_C        + More
PF00289   Biotin_carb_N
PF08326   ACC_central
PF01039   Carboxyl_trans
PF02786   CPSase_L_D2
PF00364   Biotin_lipoyl
PF03645   Tctex-1

Interpro

IPR000089   Biotin_lipoyl        + More
IPR005479   CbamoylP_synth_lsu-like_ATP-bd       
IPR029045   ClpP/crotonase-like_dom_sf       
IPR011762   COA_CT_N       
IPR005482   Biotin_COase_C       
IPR011054   Rudment_hybrid_motif       
IPR016185   PreATP-grasp_dom_sf       
IPR001882   Biotin_BS       
IPR034733   AcCoA_carboxyl       
IPR011761   ATP-grasp       
IPR005481   BC-like_N       
IPR013815   ATP_grasp_subdomain_1       
IPR011764   Biotin_carboxylation_dom       
IPR011053   Single_hybrid_motif       
IPR011763   COA_CT_C       
IPR013537   AcCoA_COase_cen       
IPR038586   Tctex-1-like_sf       
IPR005334   Tctex-1-like       

SUPFAM

SSF52096   SSF52096        + More
SSF51230   SSF51230       
SSF52440   SSF52440       
SSF51246   SSF51246       

Gene 3D

3.30.1490.20     3.30.1140.40    

ProteinModelPortal

A0A1V0M8C1   A0A0P0E5H9   H9JNW8   A0A2A4JQ91   A0A2A4JRH1   A0A0U3ATI3   + More
A0A068FK83   A0A2H1VWY0   A0A1W4XJA7   A0A1W5YLK9   A0A1Y1NDF1   D2A5X8   A0A0P4VXP9   A0A1Y1NG63   A0A0A9YFN2   A0A0A9Y5I5   A0A1W4X8U7   A0A1W4XJ22   A0A1W4X8M9   A0A224XHG0   A0A1B6DY08   A0A1B6CV39   A0A1B6M3V6   A0A1B6FL65   A0A1L8E0J6   A0A1B6LC21   A0A1L8E123   A0A1B6EF06   A0A1B6DHE3   A0A0R1DTL4   A0A0R1DM72   A0A0R1DLY0   A0A336MKR9   W4VRL7   A0A0P8XR56   B3MGC4   A0A0R1DUE2   A0A336ME20   Q7PQ11   A0A1Y9GKD4   A0A2M4CME3   A0A182LBJ6   A0A1Y9GLJ0   A0A1Y9GLJ1   A0A182V1C3   A0A2M4CMG2   A0A2M4CMA2   A0A1Y9H2E2   A0A2M4CMD9   A0A0Q5WL21   A0A0Q5WIM4   A0A0Q5WL54   A0A0J9R7W5   B4HRH5   A0A0Q5WP93   Q7JV23   A0A1I8MTZ7   A0A1I8MU01   A0A1Y9H1X3   A1Z784   A0A1Y9H1X8   A0A0J9TVV5   A0A0J9R7N5   A0A0J9R903   A0A2M3ZF48   T1PCN5   A0A084W2B0   A0A1W4VYW2   A0A0M4EUE5   B4MPP4   A0A3L8DPH9   A0A158NHP1   A0A1W4WAM9   A0A0R3NM35   A0A026WBM2   W8B0Q2   A0A0R3NLY6   A0A0R3NUF3   W8AF13   A0A1B6D1J6   A0A0Q9WGB0   A0A0Q9WG93   A0A0Q9W4U4   A0A0A9Y9M3   A0A195E2E3   A0A0A1WQB2   A0A1B0CTV1   T1ICG7   A0A195D4D1   U4UM60   F4WVP2   A0A195FW55   A0A151XFJ0   N6U7G4   Q176P0   A0A3B0J262   A0A1B6L389   A0A0G3YJ61   A0A336MSU0   A0A336KN71  

PDB

6G2I     E-value=0,     Score=2855

KEGG

101738903    K11262 acetyl-CoA carboxylase / biotin carboxylase 1 [EC:6.4.1.2 6.3.4.14 2.1.3.15] | (RefSeq) acety

PATHWAY

00061    Fatty acid biosynthesis - Bombyx mori (domestic silkworm)
00620    Pyruvate metabolism - Bombyx mori (domestic silkworm)
00640    Propanoate metabolism - Bombyx mori (domestic silkworm)
01100    Metabolic pathways - Bombyx mori (domestic silkworm)
01212    Fatty acid metabolism - Bombyx mori (domestic silkworm)

GO

GO:0005524   GO:0003989   GO:0006633   GO:0046872   GO:0016021   GO:0016874   GO:0004075   GO:0000902   GO:0071329   GO:0005977   GO:0005737   GO:0019432   GO:0009744   GO:0003824   GO:0030246   GO:0019829   GO:0005507   GO:0004713   GO:0016491   GO:0015930  

Length:

856

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.08867

Exp number, first 60 AAs:

0

Total prob of N-in:

0.00017

outside

1  -  856

 

 

Pi

241.574982

Theta

167.910706

Tajima's D

1.657351

CLR

0.352877

CSRT

0.820858957052147

Interpretation

Uncertain