Gene

KWMTBOMO14057  Validated by peptides from experiments

Pre Gene Modal

BGIBMGA011230

Annotation

PREDICTED:_putative_tRNA_pseudouridine_synthase_Pus10_[Papilio_polytes]

Location

Bomo_Chr23(-):17011210-17019382      View in EpiBrowser

Full name

Putative tRNA pseudouridine synthase Pus10      

Alternative Name

Coiled-coil domain-containing protein 139 homolog
tRNA pseudouridine 55 synthase
tRNA pseudouridylate synthase
tRNA-uridine isomerase

Location in the cell

Nuclear   Reliability : 3.034

CDS

ATGGACAATAAAGCCATCGTTAAATTCTGTAAAGAGGTAGGGTGTTGCGATATATGCTGCCTGCGTTATTTAGGGCTTAAGAACCCGGCAACTTACGAAAACTACAAAGAATACATACATAAATATACAGAAAGCGGTGTAGAAGTAGAAAATAATTCAGAAGAACAACAAATCACTAGCAATCCAGTAGACAATATAAATGGCAATAAAGATGTCAATGGCTGTGATGATGAACCACCGAAAAAGAAAAAGAAGATATCGATATGCGTAAGCTGTTTAGGTATACTCCAGGAAGAGAACTGGTCTGAATGCTTTAATATGGTCAAAGAGACTTTGGAGAAAAAACGTTACGAATGCTCAACTTTTGCATGTGCACTCTCTGCTCCGATCGCTACATTATTACGAGATAAAGCCATAATCCTACACCTGAGTGATGCCTTTAAAGATTATAAAGAAGATACCTTAACACCACTGAAGGAAGCATGGAAATGGACGTTTGGTGTCAAACTTGCCGAACAAATAGGTATGACACTAGATTCCGGAGCCATTTCACCGTTACTGATTACACTTAATATGGAGTATCCTGATGAACCACAGGAACTAGAAATCTTAAAGAAATTATCACCATCATTGTTCCAAGAGAGACAGAAGCAGAGAAGGAGGTTCACGGTTGAGTTTACCCGGCCATCAGTAGAACAGGCCATGGACAAGATTAGTCTTGAGCAGTTGAAGGGTGTCGATAAGTGGAATAAAATTCCATCGGTGGACATTGAAGCTAAGTGTGTCAGTGCTATGTGCGTGCATGCCCCTTCTTATCTGGGGGGTAGGTATATAAAATTGAGCAGAGAGCTTCCGCAGACGCCCTGGCTGATCAAGGGCAAGAGGATGATGGAATCATCCGTCCAGGAGATCTTATTCGAACCCATAGCAAAAGTATTTGACTTGACACCTGAAGACGTGGACCACAGATTGAAGTTCATGTCGGCTGGACGCGAAGACGTGGACGTGAGGTGTCTCGGTGATGGTAGACCCTTCGCTATCGAAATCACAGACCCGAGAAGAGACCTCACCGGTGACGAGCTGAAGAGGGTCTGCAAGGAGATTTCGAAAGGTGGCCAAGTGATCGTTCAGAAACTAATGCATGTCTCCAGGAACGAGTTGTCGGAACTTAAAAAGGGGGAAGAGACGAAATGCAAGACTTACGAAGCTCTGTGCATAAAGCTCGGAAATGAGAACGCTGAACCGAATATTCTGAATGGAAAAACGCCTGTCGCCGTCACCGAGGAGGACATCCAGAGGATAAACGAGTACAGGAACACCGAGGCAGGGGACGAGGCCAGGATCGTGGTGAAACAGAGAACCCCGATCCGAGTGCTGCACAGGCGCCCGCTGCTCACCAGGACCCGGAGGATATATGACGTAGTGGCCAGGAGGGTGCCTGACTACCCGCAATTGTTCACCCTCACAATCCGCACGGAAGCGGGCACGTACGTGAAGGAGTGGTGCCACGGGGAGTTCGGTCGCACCACGCCGAGCCTCCGCGACGCCGCGGGCTTCCGGGCCGACATACTGGCGCTCGACGTCACCGCGGTGCTGCTCGACTGGCCGCGACCCCAATAA

Protein

MDNKAIVKFCKEVGCCDICCLRYLGLKNPATYENYKEYIHKYTESGVEVENNSEEQQITSNPVDNINGNKDVNGCDDEPPKKKKKISICVSCLGILQEENWSECFNMVKETLEKKRYECSTFACALSAPIATLLRDKAIILHLSDAFKDYKEDTLTPLKEAWKWTFGVKLAEQIGMTLDSGAISPLLITLNMEYPDEPQELEILKKLSPSLFQERQKQRRRFTVEFTRPSVEQAMDKISLEQLKGVDKWNKIPSVDIEAKCVSAMCVHAPSYLGGRYIKLSRELPQTPWLIKGKRMMESSVQEILFEPIAKVFDLTPEDVDHRLKFMSAGREDVDVRCLGDGRPFAIEITDPRRDLTGDELKRVCKEISKGGQVIVQKLMHVSRNELSELKKGEETKCKTYEALCIKLGNENAEPNILNGKTPVAVTEEDIQRINEYRNTEAGDEARIVVKQRTPIRVLHRRPLLTRTRRIYDVVARRVPDYPQLFTLTIRTEAGTYVKEWCHGEFGRTTPSLRDAAGFRADILALDVTAVLLDWPRPQ

Description

Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

Catalytic Activity

uridine(55) in tRNA = pseudouridine(55) in tRNA

Similarity

Belongs to the pseudouridine synthase Pus10 family.

Keywords

Coiled coil   Complete proteome   Isomerase   Reference proteome   tRNA processing  

Feature

chain  Putative tRNA pseudouridine synthase Pus10

Uniprot

H9JNX6   A0A2H1W737   A0A194PU88   A0A2W1B7M0   A0A194RN45   A0A212EVT9   + More
A0A212FD27   A0A1Y1NEJ9   A0A0P4VQJ0   E0VC88   T1IET3   A0A2P8YXZ2   A0A0V0GCK4   A0A2J7R5R5   A0A023F1C6   A0A0P5UN82   A0A0P5VMG4   A0A0P5THR2   A0A0N8CQF7   A0A0P5QCS6   A0A0N8CJP9   A0A0P6BZS9   A0A0N8BVC1   A0A067QIG3   A0A088A116   A0A0P4XL53   A0A0P5D9R3   A0A0P5T5T9   A0A2C9LBZ3   A0A0M9A7V8   A0A0N8CHR3   A0A2A3ENK5   A0A131YTX1   A0A210QXC8   A0A0K8SL69   A0A0A9XA35   A0A0K2SW20   A0A224Z8T0   A0A0L7QUG7   A0A0N8BYD3   A0A1B6E3L2   Q16T84   A0A3L8DGS4   A0A1Y1Y3W1   A0A182HD50   A0A2R5LC42   B4Q5N1   B4ICS7   A0A1B6HWQ8   A0A182GY00   A0A158NQG7   A0A195ET53   F4X4U5   G3MHB3   T1J968   Q9VPK7   A0A084W4F3   A0A151HYG8   A0A151X633   A0A1U7UW97   A0A3B3RTB8   A0A182LXM9   A0A336MFF3   A0A2T7NC28   A0A1W4V331   A0A182RMR3   A0A1E1XG78   B3MUD0   D6W8D0   A0A182IQ80   A0A0L8HXZ6   A0A0A1WRW9   A0A091CUA5   G5C1Z8   A0A226EQW2   G1REG8   M3ZC52   A0A2J8XCI8   E2R061   A0A3Q7RRM1   A0A3Q2SQW1   A0A034V6E1   A0A182Q9H7   A0A0D9RPN6   A0A250YJP2   G7PM98   M3W8T7   A0A147A231   A0A182XFR1   A0A2R8ZVY3   A0A151IC49   A0A096NQX3   A0A2K5P869   F6U5F7   A0A2I3S2F4   A0A3B3BLK7   A0A2I3LIC8   A0A2K5P8D6   A0A2R8ZQ34  

EC Number

5.4.99.25

Pubmed

19121390    26354079    28756777    22118469    28004739    27129103    + More
20566863    29403074    25474469    24845553    15562597    26830274    28812685    25401762    28797301    17510324    30249741    26483478    17994087    22936249    21347285    21719571    22216098    10731132    12537572    12537569    24438588    29240929    28503490    18362917    19820115    25830018    21993625    16341006    25348373    28087693    22002653    17975172    22722832    17431167    16136131    29451363   

EMBL

BABH01009782    BABH01009783    BABH01009784    ODYU01006767    SOQ48915.1    KQ459593    + More
KPI96319.1    KZ150714    PZC70364.1    KQ460152    KPJ17421.1    AGBW02012126    OWR45599.1    AGBW02009108    OWR51656.1    GEZM01005649    JAV96008.1    GDKW01001317    JAI55278.1    DS235049    EEB10994.1    ACPB03014909    PYGN01000293    PSN49117.1    GECL01001026    JAP05098.1    NEVH01006990    PNF36171.1    GBBI01003896    JAC14816.1    GDIP01110621    JAL93093.1    GDIP01098054    LRGB01000311    JAM05661.1    KZS19858.1    GDIP01131896    JAL71818.1    GDIP01108991    JAL94723.1    GDIQ01116152    GDIP01140510    JAL35574.1    JAL63204.1    GDIP01125055    JAL78659.1    GDIP01008130    JAM95585.1    GDIQ01141291    JAL10435.1    KK853541    KDR06864.1    GDIP01239837    JAI83564.1    GDIP01164499    JAJ58903.1    GDIP01130544    JAL73170.1    KQ435716    KOX79040.1    GDIP01130543    JAL73171.1    KZ288215    PBC32621.1    GEDV01006150    JAP82407.1    NEDP02001369    OWF53363.1    GBRD01011768    JAG54056.1    GBHO01029639    JAG13965.1    HACA01000354    CDW17715.1    GFPF01012875    MAA24021.1    KQ414735    KOC62260.1    GDIQ01132795    JAL18931.1    GEDC01004790    JAS32508.1    CH477658    EAT37670.1    QOIP01000009    RLU19068.1    MCFE01000269    ORX92575.1    JXUM01033969    KQ561007    KXJ80059.1    GGLE01002903    MBY07029.1    CM000361    CM002910    EDX03181.1    KMY87250.1    CH480829    EDW45353.1    GECU01028641    JAS79065.1    JXUM01096545    KQ564272    KXJ72497.1    ADTU01023318    KQ981993    KYN31092.1    GL888679    EGI58518.1    JO841264    AEO32881.1    JH431970    AE014134    AY069446    ATLV01020330    KE525298    KFB45097.1    KQ976730    KYM76432.1    KQ982491    KYQ55760.1    AXCM01001492    UFQS01000836    UFQT01000836    SSX07180.1    SSX27523.1    PZQS01000014    PVD18724.1    GFAC01000925    JAT98263.1    CH902624    EDV33459.2    KQ971307    EFA10881.1    KQ417037    KOF94087.1    GBXI01013032    JAD01260.1    KN124472    KFO21180.1    JH172942    GEBF01006669    EHB15559.1    JAN96963.1    LNIX01000002    OXA59434.1    ADFV01009950    ADFV01009951    ADFV01009952    ADFV01009953    ADFV01009954    ADFV01009955    ABGA01395332    ABGA01395333    ABGA01395334    ABGA01395335    ABGA01395336    ABGA01395337    ABGA01395338    NDHI03003368    PNJ79750.1    PNJ79753.1    AAEX03007551    GAKP01020076    JAC38876.1    AXCN02001803    AQIB01041624    AQIB01041625    GFFW01001029    JAV43759.1    CM001288    EHH55593.1    AANG04002548    GCES01014101    JAR72222.1    AJFE02109096    AJFE02109097    AJFE02109098    AJFE02109099    AJFE02109100    AJFE02109101    KQ978069    KYM97355.1    AHZZ02005464    AHZZ02005465    JSUE03010979    JSUE03010980    JSUE03010981    CM001265    EHH22144.1    AACZ04063513   

Proteomes

UP000005204    UP000053268    UP000053240    UP000007151    UP000009046    UP000015103    + More
UP000245037    UP000235965    UP000076858    UP000027135    UP000005203    UP000076420    UP000053105    UP000242457    UP000242188    UP000053825    UP000008820    UP000279307    UP000193498    UP000069940    UP000249989    UP000000304    UP000001292    UP000005205    UP000078541    UP000007755    UP000000803    UP000030765    UP000078540    UP000075809    UP000189704    UP000261540    UP000075883    UP000245119    UP000192221    UP000075900    UP000007801    UP000007266    UP000075880    UP000053454    UP000028990    UP000006813    UP000198287    UP000001073    UP000001595    UP000002254    UP000286640    UP000265000    UP000075886    UP000029965    UP000009130    UP000011712    UP000076407    UP000240080    UP000078542    UP000028761    UP000233060    UP000006718    UP000002277    UP000261560   

PRIDE

H9JNX6    G3MHB3    Q9VPK7   

Interpro

IPR039894   Pus10-like        + More
IPR020103   PsdUridine_synth_cat_dom_sf       
IPR013087   Znf_C2H2_type       

SUPFAM

SSF55120   SSF55120       

ProteinModelPortal

H9JNX6   A0A2H1W737   A0A194PU88   A0A2W1B7M0   A0A194RN45   A0A212EVT9   + More
A0A212FD27   A0A1Y1NEJ9   A0A0P4VQJ0   E0VC88   T1IET3   A0A2P8YXZ2   A0A0V0GCK4   A0A2J7R5R5   A0A023F1C6   A0A0P5UN82   A0A0P5VMG4   A0A0P5THR2   A0A0N8CQF7   A0A0P5QCS6   A0A0N8CJP9   A0A0P6BZS9   A0A0N8BVC1   A0A067QIG3   A0A088A116   A0A0P4XL53   A0A0P5D9R3   A0A0P5T5T9   A0A2C9LBZ3   A0A0M9A7V8   A0A0N8CHR3   A0A2A3ENK5   A0A131YTX1   A0A210QXC8   A0A0K8SL69   A0A0A9XA35   A0A0K2SW20   A0A224Z8T0   A0A0L7QUG7   A0A0N8BYD3   A0A1B6E3L2   Q16T84   A0A3L8DGS4   A0A1Y1Y3W1   A0A182HD50   A0A2R5LC42   B4Q5N1   B4ICS7   A0A1B6HWQ8   A0A182GY00   A0A158NQG7   A0A195ET53   F4X4U5   G3MHB3   T1J968   Q9VPK7   A0A084W4F3   A0A151HYG8   A0A151X633   A0A1U7UW97   A0A3B3RTB8   A0A182LXM9   A0A336MFF3   A0A2T7NC28   A0A1W4V331   A0A182RMR3   A0A1E1XG78   B3MUD0   D6W8D0   A0A182IQ80   A0A0L8HXZ6   A0A0A1WRW9   A0A091CUA5   G5C1Z8   A0A226EQW2   G1REG8   M3ZC52   A0A2J8XCI8   E2R061   A0A3Q7RRM1   A0A3Q2SQW1   A0A034V6E1   A0A182Q9H7   A0A0D9RPN6   A0A250YJP2   G7PM98   M3W8T7   A0A147A231   A0A182XFR1   A0A2R8ZVY3   A0A151IC49   A0A096NQX3   A0A2K5P869   F6U5F7   A0A2I3S2F4   A0A3B3BLK7   A0A2I3LIC8   A0A2K5P8D6   A0A2R8ZQ34  

PDB

2V9K     E-value=5.76085e-56,     Score=552

KEGG

101738094    K07583 tRNA pseudouridine synthase 10 [EC:5.4.99.25] | (RefSeq) putative tRNA pseudouridine synthase

GO

GO:0009982   GO:0003723   GO:0001522   GO:0008033   GO:0106029   GO:0031119   GO:0009451   GO:0006812   GO:0019829   GO:0005507   GO:0004713   GO:0016491   GO:0015930  

PANTHER

PTHR21568  

Length:

539

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.0690099999999998

Exp number, first 60 AAs:

0.00137

Total prob of N-in:

0.00703

outside

1  -  539

 

 

Pi

197.31171

Theta

129.247114

Tajima's D

0.857205

CLR

1.323146

CSRT

0.619719014049298

Interpretation

Uncertain