Gene

KWMTBOMO14012

Pre Gene Modal

BGIBMGA011254

Annotation

PREDICTED:_homeobox_protein_PKNOX2-like_[Bombyx_mori]

Location

Bomo_Chr23(-):15917100-15940858      View in EpiBrowser

Full name

Homeobox protein PKNOX2      

Alternative Name

Homeobox protein PREP-2
PBX/knotted homeobox 2

Transcription factor

Homeobox

Location in the cell

Nuclear   Reliability : 4.465

CDS

ATGCAGGGCGGTGGAGCGCCCGCCCCAGACGCCGACCAGGCACAGTTCGAAGCGGACAAACGCGCCGTCTACAAGCATCCTCTGTTTCCCCTACTCGCGCTGCTGTTGGAGCGATGTGAGCAGGCGACGGCGGGGGTCGAGCCCCCGGCCGCCGACGCCTTCGGGGCGGACCTGCAGGCCTTCGTGCAGCATCAGCGCAGGGACAGGAGGCCCTTCCTCGTCGACGACCCGGAGATTGACGGCCTTATGATTAAGAGCATACAGGTTCTGCGCATCCACCTGCTGGAGCTGGAGAAGGTACAAGAGCTGTGTCGCGACTTCTGCGGACGGTACATCGCGTGTCTCAAGACGAAGATGCAGAGCGAGAACCTGCTCAGGACCGACTACGGCTCAGGTGGCATGGAGAGCAACAACAACTTGTCGGGGTCCCTGGAGGAGCACTCCAGCACGTCCAACTCTCCCCAGTACCAGTCCCCGGGCGCGGCGCCGTACGTGCCCCCCGCGCCGCTCGCGCCCCCCGCGGCCCTCGCCGACCTGCCCTACGCACCCCGTGACCCGCCCCAGTCCCTGATCGTGCAGGGGACGACGCCGCTCGGGCAGATCGGGGCCGCGCTGCTGCCCGCGGACTCCTACACAGGAGGCAACTCTAACAACTCGTGCTCGTCGGTGTCGGGGTCGCCGCCCCCCGACGACGACGCGGAGGAGGGCTCCAAGCGCGGAGTGCTGCCCCGCCACGCCACGCAGGCTATGCGGGCCTGGCTCTTCCAGCACCTCGTGCACCCCTACCCCACGGAGGAGGAGAAGCGGTCCCTCGCGGCGCAGACCCGCCTCACGCTCCTGCAGGTCAACAACTGGTTCATCAACGCCAGACGCCGCATCCTGCAGCCCATGCTGGACTGCTCCGACAAGCCTGGTGGAAAGAAGAGCAGGAGTGGCTCCGGCGCGAGCAGGCGGCACTGGAGCGACGCGCTGTCCAGCCCGCAGCTCGCGGCCGGTCGGTCTCCCTTCTCTATATAA

Protein

MQGGGAPAPDADQAQFEADKRAVYKHPLFPLLALLLERCEQATAGVEPPAADAFGADLQAFVQHQRRDRRPFLVDDPEIDGLMIKSIQVLRIHLLELEKVQELCRDFCGRYIACLKTKMQSENLLRTDYGSGGMESNNNLSGSLEEHSSTSNSPQYQSPGAAPYVPPAPLAPPAALADLPYAPRDPPQSLIVQGTTPLGQIGAALLPADSYTGGNSNNSCSSVSGSPPPDDDAEEGSKRGVLPRHATQAMRAWLFQHLVHPYPTEEEKRSLAAQTRLTLLQVNNWFINARRRILQPMLDCSDKPGGKKSRSGSGASRRHWSDALSSPQLAAGRSPFSI

Similarity

Belongs to the TALE/MEIS homeobox family.

Keywords

Complete proteome   DNA-binding   Homeobox   Nucleus   Reference proteome   Alternative splicing   Polymorphism  

Feature

chain  Homeobox protein PKNOX2
splice variant  In isoform 2.
sequence variant  In dbSNP:rs34936365.

Uniprot

H9JP00   A0A2H1V7B2   A0A2A4JPF5   A0A194RHY7   A0A194PTJ6   A0A212F1U8   + More
A0A2W1BCJ0   D6WYT8   A0A2R7VX38   A0A0A9YRR7   T1IS95   A0A1B6LPB0   A0A1B6JPN7   A0A1B6KKU2   A0A131YXC6   A0A2R5LE29   N6TYF5   U4U9H1   H3B7Z6   A0A1S3HK24   A0A151N3K1   F6T8R3   A0A384A898   B2GU80   A0A341B4T8   A0A2Y9M4U3   F1S778   A0A1L8FL76   A0A1U7U138   A0A2U3X4P2   A0A3Q7SHF6   S7N3F2   D4ACG5   B7ZAF3   A0A2Y9DQZ2   H9G439   L5KG81   A0A2Y9ER97   L8IM07   E1BCL1   I3LK60   F6ZFA5   A0A341B1C3   A0A1U8CYT2   A0A1S3EM44   W5PP21   E2R867   A0A2Y9HK28   A0A2Y9KHC6   A0A3Q7SEV7   A0A2Y9MAF5   F6Z692   G1R795   Q8BG99   A0A2K5DHL8   A0A0D9S4D8   A0A3Q7WI48   A0A384BWF4   D2HNK9   A0A2U3X4N9   A0A3Q7QUW7   A0A2K6EY11   K7BFH4   Q96KN3   A0A2K5RCP1   A0A0G2JYQ2   A0A2K6ADK1   A0A2R9CF88   A0A2K5MSF1   A0A2K5J553   H2NFS2   G1TU50   I3M3T9   M3Y4Z3   A0A091DM76   A0A2K6CLS7   G7PPL8   A0A1U7UB01   G7NCW8   H0WLI8   A0A2K6SI10   B7Z3G7   A0A2Y9DR43   A0A3B4E7G2   A0A286X926   G5APE6   Q5R6L1   A0A340XQN0   R7UQU2   G3WWV9   K7FSQ9   F7D6U6   A0A1S2ZKC3   R4G981   A0A340XU21   A0A3Q3DUT9   A0A3Q1M9I7   A0A340XQP9   A0A096MJK1   B7Z9N6  

Pubmed

19121390    26354079    22118469    28756777    18362917    19820115    + More
25401762    26830274    23537049    9215903    22293439    20431018    27762356    15057822    21881562    23258410    22751099    19393038    19892987    20809919    16341006    25243066    12412021    16141072    15489334    24813606    20010809    16136131    14702039    17974005    16554811    11549286    11972344    22722832    21993624    22002653    17431167    25319552    21993625    23254933    21709235    17381049    17495919   

EMBL

BABH01009706    BABH01009707    ODYU01001032    SOQ36686.1    NWSH01000978    PCG73290.1    + More
KQ460152    KPJ17443.1    KQ459593    KPI96298.1    AGBW02010789    OWR47709.1    KZ150299    PZC71544.1    KQ971357    EFA08393.1    KK854143    PTY12074.1    GBHO01007898    GBHO01007897    GBHO01007896    JAG35706.1    JAG35707.1    JAG35708.1    JH431426    GEBQ01014452    JAT25525.1    GECU01022814    GECU01006527    JAS84892.1    JAT01180.1    GEBQ01027914    JAT12063.1    GEDV01005397    JAP83160.1    GGLE01003664    MBY07790.1    APGK01056079    APGK01056080    KB741274    ENN71332.1    KB632130    ERL88973.1    AFYH01032080    AFYH01032081    AFYH01032082    AFYH01032083    AFYH01032084    AFYH01032085    AFYH01032086    AFYH01032087    AFYH01032088    AFYH01032089    AKHW03004084    KYO31362.1    AAMC01071055    AAMC01071056    AAMC01071057    AAMC01071058    AAMC01071059    AAMC01071060    AAMC01071061    AAMC01071062    AAMC01071063    AAMC01071064    BC166172    AAI66172.1    AEMK02000070    CM004478    OCT72327.1    KE163022    EPQ10565.1    AABR07073386    AK316268    BAH14639.1    AAWZ02026254    AAWZ02026255    AAWZ02026256    AAWZ02026257    AAWZ02026258    AAWZ02026259    AAWZ02026260    KB030791    ELK09786.1    JH880993    ELR57356.1    AMGL01061292    AMGL01061293    AMGL01061294    AMGL01061295    AMGL01061296    AMGL01061297    AAEX03003389    GAMS01002685    GAMR01010214    GAMR01010213    GAMR01010212    GAMR01010211    GAMQ01003371    GAMP01009945    GAMP01009944    GAMP01009943    JAB20451.1    JAB23718.1    JAB38480.1    JAB42810.1    ADFV01057512    ADFV01057513    ADFV01057514    ADFV01057515    AF487460    AB086817    AK082952    BC050865    AQIB01089469    AQIB01089470    AQIB01089471    ACTA01179063    ACTA01187061    GL193090    EFB15963.1    AACZ04006713    GABC01005679    GABF01009291    GABE01003773    NBAG03000239    JAA05659.1    JAA12854.1    JAA40966.1    PNI65647.1    AK298999    BX648615    AP000708    AP001007    AP003061    AP003069    BC045626    AB065001    AJ417081    AJFE02068394    AJFE02068395    AJFE02068396    ABGA01177259    ABGA01177260    ABGA01177261    ABGA01177262    ABGA01177263    ABGA01177264    ABGA01177265    ABGA01177266    ABGA01177267    ABGA01177268    NDHI03003374    PNJ75334.1    AAGW02009643    AGTP01102079    AGTP01102080    AGTP01102081    AGTP01102082    AGTP01102083    AGTP01102084    AGTP01102085    AGTP01102086    AGTP01102087    AGTP01102088    AEYP01027083    AEYP01027084    AEYP01027085    AEYP01027086    AEYP01027087    AEYP01027088    AEYP01027089    AEYP01027090    AEYP01027091    AEYP01027092    KN122286    KFO31385.1    AQIA01022586    AQIA01022587    AQIA01022588    AQIA01022589    AQIA01022590    CM001289    EHH56887.1    JSUE03013613    JSUE03013614    JSUE03013615    JSUE03013616    JU320907    CM001266    AFE64663.1    EHH23571.1    AAQR03130541    AAQR03130542    AAQR03130543    AAQR03130544    AK295857    BAH12203.1    AAKN02024652    AAKN02024653    AAKN02024654    AAKN02024655    JH166336    EHA98906.1    CR860477    AMQN01007710    KB301235    ELU05786.1    AEFK01116214    AEFK01116215    AEFK01116216    AEFK01116217    AEFK01116218    AEFK01116219    AGCU01080836    AGCU01080837    AGCU01080838    AGCU01080839    AGCU01080840    AGCU01080841    AGCU01080842    AGCU01080843    AGCU01080844    AGCU01080845    AK316001    BAH14372.1   

Proteomes

UP000005204    UP000218220    UP000053240    UP000053268    UP000007151    UP000007266    + More
UP000019118    UP000030742    UP000008672    UP000085678    UP000050525    UP000008143    UP000261681    UP000252040    UP000248483    UP000008227    UP000186698    UP000189704    UP000245340    UP000286640    UP000002494    UP000248480    UP000001646    UP000010552    UP000009136    UP000002281    UP000189706    UP000081671    UP000002356    UP000002254    UP000248481    UP000248482    UP000008225    UP000001073    UP000000589    UP000233020    UP000029965    UP000286642    UP000261680    UP000291021    UP000008912    UP000286641    UP000233160    UP000002277    UP000005640    UP000233040    UP000233140    UP000240080    UP000233060    UP000233080    UP000001595    UP000001811    UP000005215    UP000000715    UP000028990    UP000233120    UP000009130    UP000233100    UP000006718    UP000005225    UP000233220    UP000261440    UP000005447    UP000006813    UP000265300    UP000014760    UP000007648    UP000007267    UP000002280    UP000079721    UP000264820   

PRIDE

H9JP00    F1S778    D4ACG5    B7ZAF3    I3LK60    Q8BG99    + More
Q96KN3    Q5R6L1   

Pfam

PF05920   Homeobox_KN        + More
PF16493   Meis_PKNOX_N

Interpro

IPR032453   PKNOX/Meis_N        + More
IPR009057   Homeobox-like_sf       
IPR008422   Homeobox_KN_domain       
IPR001356   Homeobox_dom       

SUPFAM

SSF46689   SSF46689       

CDD

cd00086  homeodomain

ProteinModelPortal

H9JP00   A0A2H1V7B2   A0A2A4JPF5   A0A194RHY7   A0A194PTJ6   A0A212F1U8   + More
A0A2W1BCJ0   D6WYT8   A0A2R7VX38   A0A0A9YRR7   T1IS95   A0A1B6LPB0   A0A1B6JPN7   A0A1B6KKU2   A0A131YXC6   A0A2R5LE29   N6TYF5   U4U9H1   H3B7Z6   A0A1S3HK24   A0A151N3K1   F6T8R3   A0A384A898   B2GU80   A0A341B4T8   A0A2Y9M4U3   F1S778   A0A1L8FL76   A0A1U7U138   A0A2U3X4P2   A0A3Q7SHF6   S7N3F2   D4ACG5   B7ZAF3   A0A2Y9DQZ2   H9G439   L5KG81   A0A2Y9ER97   L8IM07   E1BCL1   I3LK60   F6ZFA5   A0A341B1C3   A0A1U8CYT2   A0A1S3EM44   W5PP21   E2R867   A0A2Y9HK28   A0A2Y9KHC6   A0A3Q7SEV7   A0A2Y9MAF5   F6Z692   G1R795   Q8BG99   A0A2K5DHL8   A0A0D9S4D8   A0A3Q7WI48   A0A384BWF4   D2HNK9   A0A2U3X4N9   A0A3Q7QUW7   A0A2K6EY11   K7BFH4   Q96KN3   A0A2K5RCP1   A0A0G2JYQ2   A0A2K6ADK1   A0A2R9CF88   A0A2K5MSF1   A0A2K5J553   H2NFS2   G1TU50   I3M3T9   M3Y4Z3   A0A091DM76   A0A2K6CLS7   G7PPL8   A0A1U7UB01   G7NCW8   H0WLI8   A0A2K6SI10   B7Z3G7   A0A2Y9DR43   A0A3B4E7G2   A0A286X926   G5APE6   Q5R6L1   A0A340XQN0   R7UQU2   G3WWV9   K7FSQ9   F7D6U6   A0A1S2ZKC3   R4G981   A0A340XU21   A0A3Q3DUT9   A0A3Q1M9I7   A0A340XQP9   A0A096MJK1   B7Z9N6  

PDB

1X2N     E-value=3.52629e-23,     Score=267

KEGG

101747000    no KO assigned | (RefSeq) homeobox protein PKNOX2-like

GO

GO:0003677   GO:0006355   GO:0005634   GO:0045171   GO:0003785   GO:0005737   GO:0005654   GO:0015630   GO:0051015   GO:0015629   GO:0006357   GO:0000977   GO:0043565   GO:0000981   GO:0016021   GO:0004930   GO:0007186   GO:0016020   GO:0004713   GO:0016491   GO:0015930  

Subcellular location

Nucleus  

Length:

338

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.00125

Exp number, first 60 AAs:

0.00015

Total prob of N-in:

0.00384

outside

1  -  338

 

 

Pi

182.073811

Theta

147.493203

Tajima's D

1.077811

CLR

0.411384

CSRT

0.68331583420829

Interpretation

Uncertain