Gene

KWMTBOMO13998

Pre Gene Modal

BGIBMGA011263

Annotation

PREDICTED:_zinc_finger_C4H2_domain-containing_protein_[Bombyx_mori]

Location

Bomo_Chr23(-):15674583-15683901      View in EpiBrowser

Full name

Zinc finger C4H2 domain-containing protein      

Alternative Name

Hepatocellular carcinoma-associated antigen 127 homolog
Hepatocellular carcinoma-associated antigen 127-like

Location in the cell

Nuclear   Reliability : 4.431

CDS

ATGACCGCTGAAAACGAAAGAGAGATATATCACAAGCTGGAGGCGATGAAGGAAATAAGGAACAAAACTATAACCCTGGAGAGACTAAAGCGCAGCATCATGACGGAGGTGCGCAGCGGTGATCAAGAGGGGCGTTGTCTAGCTCAGTACAAACGCGAGATGGAGCTGCTGCAGCAGGAGAAGATGAGCCATGTGGAGGAACTTCGACAGATACATGCCGATATTAATGCAATGGAAACAGTAATAAAGCAGACAGAAGAGAGCATGACCCGCAAGTTGTCGAGCGCGTCCCGTCTACACGAGGAGTATCGACCGTTGAAGGCTGAGGTGGACCTGCTGCGGAGACAGTACCTGGGCCTGGAGCGACTCCCCGACCTGCACGAGGAGGACGGCAGCCCCATCACGCCGGACCGGTTCCCGCGCGCCGTGCCGCCGCCCCCGCCGCGCGGCTGCTTCCCCCCGCTGGCGAGCCGCAAGCCGCCCCCGCCCCCCGCCGCCTTCAGGTCTGCTCTAGAACAAGATTTCATTACCGTCTCGCTGAGACAGCAGCCGCCGCCGATGAAGTCGTGTCTGTCGTGCCACCAGCAGATACACCGGAACGCGCCGATCTGTCCGCTCTGCAAGGCCAAGAGTCGCTCCAGGAATCCCAAGAAACCCAAGAAGAAATAG

Protein

MTAENEREIYHKLEAMKEIRNKTITLERLKRSIMTEVRSGDQEGRCLAQYKREMELLQQEKMSHVEELRQIHADINAMETVIKQTEESMTRKLSSASRLHEEYRPLKAEVDLLRRQYLGLERLPDLHEEDGSPITPDRFPRAVPPPPPRGCFPPLASRKPPPPPAAFRSALEQDFITVSLRQQPPPMKSCLSCHQQIHRNAPICPLCKAKSRSRNPKKPKKK

Description

Plays a role in GABAergic and V2 interneurons differentiation (PubMed:26056227). Involved in motoneuron development and in neuromuscular junction formation (PubMed:23623388).

Keywords

Cell junction   Cell membrane   Coiled coil   Complete proteome   Cytoplasm   Developmental protein   Differentiation   Membrane   Metal-binding   Nucleus   Postsynaptic cell membrane   Reference proteome   Synapse   Zinc   Zinc-finger  

Feature

chain  Zinc finger C4H2 domain-containing protein

Uniprot

A0A2H1VUV8   A0A212FHT0   A0A1W4WLF5   A0A2P8Z9P9   T1JMR9   A0A195C5T9   + More
A0A2J7Q0A1   W5NBJ5   V5HBM9   B7PYR5   H9GK37   A0A0P7XAY8   A0A1V4KXY1   G1MQ05   A0A151NPE4   A0A3L8SJ90   A0A218V3H8   K7GFJ3   U3I7S9   U3JNW9   A0A0Q3X9S7   A0A1U7SAL4   H0YXB4   H0W5U1   A0A1E1X5K8   Q7T3I0   A0A1W4Y6A6   A0A023GGK6   G3T4Y5   A0A1S3AKR2   A0A2Y9IG46   M3YGP8   A0A224Z0A1   A0A131Z167   L7M5N8   A0A1S3GLJ0   G3ICB7   I3MUZ0   A0A1U7QL27   A0A250YCY0   B1WC48   G5C7V9   A0A2K6E8M9   G1T5B2   A0A2I3GEZ6   A0A2K5YE81   A0A0D9RHR0   A0A3Q7NFJ5   A0A2R9C0I7   A0A2K5DUV8   A0A2K6RKD6   A0A2I2UTC5   A0A2K5MLD6   A0A1U7UL73   A0A2U3WKX6  

Pubmed

22118469    29403074    25765539    21881562    20838655    22293439    + More
30282656    17381049    20360741    21993624    28503490    15256591    23594743    23623388    26056227    28797301    26830274    25576852    21804562    28087693    15489334    15057822    21993625    22722832    25362486    17975172   

EMBL

ODYU01004593    SOQ44631.1    AGBW02008466    OWR53295.1    PYGN01000136    PSN53214.1    + More
JH431533    KQ978292    KYM95546.1    NEVH01019993    PNF22009.1    AHAT01015623    AHAT01015624    GANP01003618    JAB80850.1    ABJB010167120    ABJB010187109    ABJB010491298    ABJB010597974    ABJB010673708    DS821669    EEC11737.1    AAWZ02026469    AAWZ02026470    JARO02002092    KPP73552.1    LSYS01001150    OPJ89309.1    AKHW03002524    KYO38335.1    QUSF01000018    RLW02566.1    MUZQ01000059    OWK60499.1    AGCU01172685    AGCU01172686    AGTO01000775    LMAW01000147    KQL60428.1    ABQF01018351    ABQF01018352    AAKN02052843    AAKN02052844    GFAC01004674    JAT94514.1    AY648796    CR812469    BC053110    GBBM01002409    JAC33009.1    AEYP01103559    AEYP01103560    AEYP01103561    AEYP01103562    GFPF01008346    MAA19492.1    GEDV01004015    JAP84542.1    GACK01005862    JAA59172.1    JH001906    EGW12681.1    AGTP01082009    AGTP01082010    AGTP01082011    GFFW01003379    JAV41409.1    AABR07038957    BC162002    AAI62002.1    JH173714    GEBF01003797    EHB17620.1    JAN99835.1    AAGW02057254    ADFV01072477    ADFV01072478    AQIB01144580    AQIB01144581    AQIB01144582    AQIB01144583    AJFE02057738    AJFE02057739    AANG04000501   

Proteomes

UP000007151    UP000192223    UP000245037    UP000078542    UP000235965    UP000018468    + More
UP000001555    UP000001646    UP000034805    UP000190648    UP000001645    UP000050525    UP000276834    UP000197619    UP000007267    UP000016665    UP000051836    UP000189705    UP000007754    UP000005447    UP000000437    UP000192224    UP000007646    UP000079721    UP000248482    UP000000715    UP000081671    UP000001075    UP000005215    UP000189706    UP000002494    UP000006813    UP000233120    UP000001811    UP000001073    UP000233140    UP000029965    UP000286641    UP000240080    UP000233020    UP000233200    UP000011712    UP000233060    UP000189704    UP000245340   

PRIDE

G3ICB7   

Pfam

PF10146   zf-C4H2

Interpro

IPR018482   Znf-C4H2       

ProteinModelPortal

A0A2H1VUV8   A0A212FHT0   A0A1W4WLF5   A0A2P8Z9P9   T1JMR9   A0A195C5T9   + More
A0A2J7Q0A1   W5NBJ5   V5HBM9   B7PYR5   H9GK37   A0A0P7XAY8   A0A1V4KXY1   G1MQ05   A0A151NPE4   A0A3L8SJ90   A0A218V3H8   K7GFJ3   U3I7S9   U3JNW9   A0A0Q3X9S7   A0A1U7SAL4   H0YXB4   H0W5U1   A0A1E1X5K8   Q7T3I0   A0A1W4Y6A6   A0A023GGK6   G3T4Y5   A0A1S3AKR2   A0A2Y9IG46   M3YGP8   A0A224Z0A1   A0A131Z167   L7M5N8   A0A1S3GLJ0   G3ICB7   I3MUZ0   A0A1U7QL27   A0A250YCY0   B1WC48   G5C7V9   A0A2K6E8M9   G1T5B2   A0A2I3GEZ6   A0A2K5YE81   A0A0D9RHR0   A0A3Q7NFJ5   A0A2R9C0I7   A0A2K5DUV8   A0A2K6RKD6   A0A2I2UTC5   A0A2K5MLD6   A0A1U7UL73   A0A2U3WKX6  

KEGG

101736418    no KO assigned | (RefSeq) zinc finger C4H2 domain-containing protein

GO

GO:0045666   GO:0045211   GO:0005634   GO:0005737   GO:0030054   GO:0007399   GO:0046872   GO:0048666   GO:0021522   GO:0007528   GO:0048665  

PANTHER

PTHR31058  

Subcellular location

Nucleus  
Cytoplasm  
Cell junction  
Synapse  
Postsynaptic cell membrane  

Length:

222

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0

Exp number, first 60 AAs:

0

Total prob of N-in:

0.29135

outside

1  -  222

 

 

Pi

211.091589

Theta

162.685761

Tajima's D

0.257046

CLR

0.643728

CSRT

0.447227638618069

Interpretation

Possibly Positive selection