Silkworm Genome Informatics Database

Gene

KWMTBOMO13990

Pre Gene Modal

BGIBMGA011269

Annotation

PREDICTED:_tyrosine-protein_phosphatase_non-receptor_type_14_[Papilio_machaon]

Location

Bomo_Chr23(-):15375711-15389436 View in EpiBrowser

Location in the cell

Nuclear Reliability : 2.832

CDS

ATGCCTTTTAAGTTGAAGTTGAAGAAAACTCGGCAATACAACGTCGCTTCGAAGAGTTTATTCGTGATCAGCGTCGAACTTCTAGATGGAGGTGTGGCGGACTGTACGCTGTCCGTGGACAGCTCTGGACAGGAGTGCTTGGATAACGTGTGTCAGCGACAGGCGATAAACCAGCCTGAATTTTTTGGTCTTCGGTATGTCAACAGGAATCAGCAGGCTCGATGGGTACAGCTAGACAGGCCGCTCAAACGTCAGCTAGAGAAACATGCGTCCTCCCACCAACTATACCTACGCGTCATGTACTATGTGATCAATGGGACCAATTTAATCACAGATGAAGTTACTCGGTACCACTATTTTTTACAGTTGAAAAATGATCTGATTGAAGGACGTTTGATCTGCGACTGTCAGCAAGCCGTTATATTAGCATCATATAGTAGACAAGCTGAGTATGGCAATCATGATAGAGAGAGGCATACAGTGGAGTATTTAAAGAATCTGTTAACATTTCCAAAGCAAATTGTCGATGGAGGACAGATTATTGACGGCAGCACTCTAGCTGAGACGGGGAGGTTAGAGTGGCTAACAGAAGCTGTAATTCAACAACATATAGCCCTACATAATATGTCCCAAGCTCAAGCCGAAGAGGGGTTCATCACGACGTGCCAACAGCTACGGGGCTACGGCCAAGAGCTGTACACAGCGAAGGATCCACTTGGACAGAAGGAGGTCACCGTTGCCATATCTTTGACCGGTATCACTGTGCTGGTCGATAATTCTGATACACCTCATTTTTACAGGTGGATGGACATAACGAACGTAATCAACCACAAGCGGACGTTCAGCATCGAGTGCCAGCGGCAGACTGAGAGCGCGACCTTCACGCTCGCCAGCCCCGAGGACGGGAAGTACGTGTGGCGCATGTGCGTGCTGCAGCACACCTTCTACATGCAGCACCGCGCCGCGCTCAGTGACCACAAGCCGCCGCGACCCGACCACCGCATTCATTTCCAGGAGCACGGTCTGTCAGAGAGCCGCGAGGAGTTGGACGTTCGAGAAGCGGGCAGCGTGTCCCGCCTGGAGCCGCTGACGAACGCACACCGAGCGCATTCCACCTCCTGCCTCGAGCTGGCAGAGAACCACCCTCAGCCCCACCCCCTGCAGAGGAACAGAGCGCTCTTACCGTCGTACCGGCCGGCTCCAGACTACGAGACGGCCATTCAACAAAAATACGCCCAGCAAAGGGCCGAAGCACAGCTCCGATACCAAAACCACCACGCGCACACGCAGCTAGTCACCGCCACCGCCAAACCGCTCATATACGGGTCGCACCCCGACATACACCGGGTACACTACCCTGACGTCACCAGGCACACCCTCACGCAGGGGGTGGCTGCCACTGACGACTATGCCTACGGCTTGAAATTCGTCGGCCCGAACTACCCCTTCGCAGTCAATCCTAACGTGCAGACGGATTTAAATCAATTACATTTCGTCAACGTTTACAAACCGCCCCCTCCTTACCCTTCCAACGGCTTGGCTTCCAATTCCACTCCGGACCTGGCGGCCGCAAGTCAAGCCTTAAATTACCACCGGGGGTACATCAACTCCCACGTTTCTGGTTCTAGTCCTGATCTGGTGTCCACCAGAACGGCGTTAAACAGGCAGTATTTAGCGTATCTGAACAACACCCACGTGAACTACGGCAGGGTGCTGCCTGGGGCCCACGGCACTTACAACAACTTGACGTCGGTGCTAGACCCCAAACCCCACATCATCATGGACCCGCACCACATTTCAGATAATATCCAAAAAGTTTATGACGAAAGAGGGAACATCATGTACTCCATGCCGATGCACAGACTGCCCTACCAGAGACATTTAGTTTTACCTCAGCAGCAAGTCAGCAGCAACGCCCAGGAACCGATCTACGAAAACGTCCCCCTGCCCTGGCAGAGCGATGGCCAAGTCGTTCGGGACAGGGCCCAGAGTCTGACCACTACGGACGAGATAGCGCGTCTCAACGAACGCAACAGCAGACGTCCGACGCTGAACCACGGGAACTTGTCCAAGAACGCCCCCAACGTGCCCAACTACGTACCCGTGAACGTGGACAACCCGGACGGCCACTACGTCAACGCTCAGATCATAAGTCGGGTCAAAGAAACGAGCGGCTCTAAAGAAATCGACACGTTAACAAAAACCGACGAATTGGAGAACGTCACAGGGTCGGTGGACCGGCTGTCGCTCCAGCACGACCAGCCCTACGACGAGACGCCCTACCAAAGTCTGTCCACGCACAAGCTGTCCAACAACAACACGAGCAGCAAACCGAACGACAACGTCACCTCGATATCCGTGCCCGACGTGCGGCCAGACGACACCGCACTCTCGCACGCCAGTGCTGGCTCCAGTTCCATCATGAACTCGACCTACAGCACTGTGGAAACTGAGAAGAACAGCAGCGTCAGCAGCAAGGAGAAGAAGAGGAGGAGATGGGGAGTGTTCATGGGCCGGGCGAGCAAGGCCGCGGACGTGAAGAGCGCGACGCTGGGCCGCGACCGCGCCAAGGGGCCGCACCCCGCCAACAAGCACCGCTGGTCCACGGGGCTGCCCAAGTGTCAGCCCTTGCCGCCCAGCATCACCAAAGAAACTATGTGCCAAATCTTAGAACGGAAAATGTCCGACGAGCAGCTCGCGTTCGCATACGAACAGATCCCGAAGGGGCGGGAGGCCGGCGCGGAGTGCGACACGGCCCTCCTGGCGAACAACTACAGTCTCAACTCGCGAGCCGAGACCCTGCCCTACGAGGACAACAGGGTCAAGCTGCAGCCCTCTCCCGGCAACCCGCTGGGCTACGTCAACGCGTCGCACGTGACGATGACAGTGGGCAGCAGCCAACGTTTCTACGTGGTGGGAGCCCTGAGCCCGGGCTGCGGTCCGGCGCTGTGGGAGGCGGTGTGGCGCGTGGGGGCACGGCTGCTGGTCGTGCTGGACCACCCCGACGCCTGTCTGCCGCCCGAGAACTCCTCCAGGGAGTACGGGAAGCTGGAGGTGTGGTGCGGCCGCTGGTCCCGCACGGCGTGGGGGGGCTCGGCTCGCGTGCGGGTGGGCGCCACGGGCGGGCGGCCCCCCCGGCACCTGTGGCACGTGCACTACCGGGCCTGGACGGCGCAGCACGTGCCCGAGCACCTGCACGACTTCTTAGATTTCCTGTCAGAGATCAAAGCCCTCCGTCTGGCGGGGGAGGCGGAGGGCAGTCCGCTGGTGGGCGGCGCCTGCCCCGCGTGGTACTGCTGCGGGGAGGGAGCCGGCCGCAGCGGCACGGCGCTGGCTGCCGACCTGCTCACCGACATACTGGACCACAACCAGGAGCTGGACATCCCCCGCACAATAAGCATGCTGCACCAGCAGAGAGCGAATCTCATACAGAACGTTCATCAATACAAGTTCCTCCACCAAGTTCTGCTACAATATCTGAAACATTCTAGACTCATTTAG

Protein

MPFKLKLKKTRQYNVASKSLFVISVELLDGGVADCTLSVDSSGQECLDNVCQRQAINQPEFFGLRYVNRNQQARWVQLDRPLKRQLEKHASSHQLYLRVMYYVINGTNLITDEVTRYHYFLQLKNDLIEGRLICDCQQAVILASYSRQAEYGNHDRERHTVEYLKNLLTFPKQIVDGGQIIDGSTLAETGRLEWLTEAVIQQHIALHNMSQAQAEEGFITTCQQLRGYGQELYTAKDPLGQKEVTVAISLTGITVLVDNSDTPHFYRWMDITNVINHKRTFSIECQRQTESATFTLASPEDGKYVWRMCVLQHTFYMQHRAALSDHKPPRPDHRIHFQEHGLSESREELDVREAGSVSRLEPLTNAHRAHSTSCLELAENHPQPHPLQRNRALLPSYRPAPDYETAIQQKYAQQRAEAQLRYQNHHAHTQLVTATAKPLIYGSHPDIHRVHYPDVTRHTLTQGVAATDDYAYGLKFVGPNYPFAVNPNVQTDLNQLHFVNVYKPPPPYPSNGLASNSTPDLAAASQALNYHRGYINSHVSGSSPDLVSTRTALNRQYLAYLNNTHVNYGRVLPGAHGTYNNLTSVLDPKPHIIMDPHHISDNIQKVYDERGNIMYSMPMHRLPYQRHLVLPQQQVSSNAQEPIYENVPLPWQSDGQVVRDRAQSLTTTDEIARLNERNSRRPTLNHGNLSKNAPNVPNYVPVNVDNPDGHYVNAQIISRVKETSGSKEIDTLTKTDELENVTGSVDRLSLQHDQPYDETPYQSLSTHKLSNNNTSSKPNDNVTSISVPDVRPDDTALSHASAGSSSIMNSTYSTVETEKNSSVSSKEKKRRRWGVFMGRASKAADVKSATLGRDRAKGPHPANKHRWSTGLPKCQPLPPSITKETMCQILERKMSDEQLAFAYEQIPKGREAGAECDTALLANNYSLNSRAETLPYEDNRVKLQPSPGNPLGYVNASHVTMTVGSSQRFYVVGALSPGCGPALWEAVWRVGARLLVVLDHPDACLPPENSSREYGKLEVWCGRWSRTAWGGSARVRVGATGGRPPRHLWHVHYRAWTAQHVPEHLHDFLDFLSEIKALRLAGEAEGSPLVGGACPAWYCCGEGAGRSGTALAADLLTDILDHNQELDIPRTISMLHQQRANLIQNVHQYKFLHQVLLQYLKHSRLI

Catalytic Activity

H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate

Uniprot

H9JP15 A0A0N0PBN9 A0A2H1VTE3 A0A194QHS3 A0A212FHT4 A0A0L7KW11 + More
A0A1Y1NET6 A0A1B0CB99

Pubmed

19121390 26354079 22118469 26227816 28004739

EMBL

BABH01009641 BABH01009642 BABH01009643 KQ460880 KPJ11525.1 ODYU01004315 + More
SOQ44058.1 KQ458761 KPJ05103.1 AGBW02008466 OWR53288.1 JTDY01005242 KOB67209.1 GEZM01007074 JAV95420.1 AJWK01004930 AJWK01004931 AJWK01004932 AJWK01004933

Proteomes

UP000005204 UP000053240 UP000053268 UP000007151 UP000037510 UP000092461 + More

PRIDE

H9JP15

Pfam

PF00102   Y_phosphatase        + More
PF00373   FERM_M
PF09380   FERM_C
PF09379   FERM_N

Interpro

IPR000299   FERM_domain        + More
IPR029071   Ubiquitin-like_domsf
IPR000242   PTPase_domain
IPR041782   PTPN14/21_FERM_C
IPR018980   FERM_PH-like_C
IPR019748   FERM_central
IPR011993   PH-like_dom_sf
IPR000387   TYR_PHOSPHATASE_dom
IPR018979   FERM_N
IPR019747   FERM_CS
IPR035963   FERM_2
IPR019749   Band_41_domain
IPR029021   Prot-tyrosine_phosphatase-like
IPR014352   FERM/acyl-CoA-bd_prot_sf
IPR003595   Tyr_Pase_cat
IPR016130   Tyr_Pase_AS

SUPFAM

SSF52799   SSF52799        + More
SSF54236   SSF54236
SSF47031   SSF47031

Gene 3D

1.20.80.10 2.30.29.30 3.90.190.10

CDD

cd14473 FERM_B-lobe
cd13188 FERM_C_PTPN14_PTPN21

ProteinModelPortal

H9JP15 A0A0N0PBN9 A0A2H1VTE3 A0A194QHS3 A0A212FHT4 A0A0L7KW11 + More
A0A1Y1NET6 A0A1B0CB99

PDB

2BZL E-value=1.29689e-32, Score=354

KEGG

101735618 K18025 tyrosine-protein phosphatase non-receptor type 14/21 [EC:3.1.3.48] | (RefSeq) tyrosine-protei

GO

GO:0005856 GO:0004725 GO:0006470 GO:0016311 GO:0016791 GO:0007166 GO:0016020 GO:0004713 GO:0016491 GO:0015930

Length:

1166

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.0464600000000001

Exp number, first 60 AAs:

0.01787

Total prob of N-in:

0.00200

outside

1 - 1166

Pi

268.03041

Theta

195.824694

Tajima's D

1.246101

CLR

0.07635

CSRT

0.725513724313784

Interpretation

Uncertain

Sequence

Summary

Ontologies

Topology

Population Genetic Test Statistics