Silkworm Genome Informatics Database

Gene

KWMTBOMO13980

Pre Gene Modal

BGIBMGA011333

Annotation

E3_ubiquitin-protein_ligase_Mdm2-like_[Bombyx_mori]

Location

Bomo_Chr23(+):15246357-15255411 View in EpiBrowser

Location in the cell

Nuclear Reliability : 4.49

CDS

ATGAACACAACATTTTGTTCAGAAACTTCAGTAAGCCGACGATGTTCGACTGAGACAATCTACAGCATACAAGGAAAAGAAACAGATTTCGCGCGAGACACCAGCGACACAGATGCAAGTATATTCGATACAGACGCCGAGATCGAGTTCGAGCCGGCCTCTGATGATGAAGAGGACCAGGCGCCGGTGGACGAGGACACGTCGGCGTCTTTCACTGATGGTGAAATAATAAAGACCAAAGTGCTAGAGGTGAGCGTGGGCGACGACGGCGACCTGCAGCTCGCGGACTCTGAGCAGACTGACTCGCAGGACAGCGACAGCGAGATCGACCTGTACGACTTCTGGCATTGCATCAAGTGCAGAGCCGAGAACAACGTTCCGTTTTATAGATATTGTCAGAAGTGCTTTCAGGTCCGCAAAAACTTCTTTCCTCCGCGGCCGAAACGTAAACGCAAACGCGGCACGACGGTCACCCCGGAGCTGGACGCGGTGCCCAGGACTCTGTCACAGGACTCCGGCATCCAGTCCGTGCACAGTCAAGAACTGTTCAACAGCCAGGACGCGACCCACGGTGAGGGCACTTCGCGAGACGTTGACAGTAGCGCTGAGTTCACAGGTCGAGCGAGGAAGAGACGCGCCCGGTCGGTCGACGGCGGCTCCAAGCGAACGAAGCTCGCCTCTGCCTCCGGATCCGGATCCGACTCCGACTCTGGAGGCAACTCGGAGTCCCTGACCAAGTCCGTCAGCGATCCGTCCGTGGCGATCGACGAGCCGCTGAAAATGACGAAAAAAGTAATATCGGATAGGATCAAACAAAAGCTAGACAAGGAGCTGTGCATCGTGTGCGACTCCGAACCCAAGACCGGCGTGTTCGTGCACGGGCACCTCGCGCACATCTGCTGCTGCTACAAGTGCGCCGTCAAGGTGTGGGCGCGCGCCCGCCGCTGCCCCGTCTGCAACCGCAGGGTCAGCAACGTGCTGCGCGCCGTCGTGCTATAG

Protein

MNTTFCSETSVSRRCSTETIYSIQGKETDFARDTSDTDASIFDTDAEIEFEPASDDEEDQAPVDEDTSASFTDGEIIKTKVLEVSVGDDGDLQLADSEQTDSQDSDSEIDLYDFWHCIKCRAENNVPFYRYCQKCFQVRKNFFPPRPKRKRKRGTTVTPELDAVPRTLSQDSGIQSVHSQELFNSQDATHGEGTSRDVDSSAEFTGRARKRRARSVDGGSKRTKLASASGSGSDSDSGGNSESLTKSVSDPSVAIDEPLKMTKKVISDRIKQKLDKELCIVCDSEPKTGVFVHGHLAHICCCYKCAVKVWARARRCPVCNRRVSNVLRAVVL

Similarity

Belongs to the MDM2/MDM4 family.

Uniprot

H9JP79 U3N2H7 A0A2A4JJ97 A0A2A4JJS1 A0A2H1WUF3 A0A1E1WHW1 + More
A0A212FHV9 A0A0N1ICZ6 A0A1B6CGP3 A0A139WMU9 A0A0C9RFT5 A0A194QJM5 A0A0C9QYX6 A0A2U9B352 H2T886

Pubmed

19121390 22118469 26354079 18362917 19820115 21551351 + More

EMBL

BABH01009629 JF507604 AEE43922.1 KF201646 AGW21579.1 NWSH01001330 + More
PCG71664.1 PCG71663.1 ODYU01011140 SOQ56699.1 GDQN01006235 GDQN01004469 JAT84819.1 JAT86585.1 AGBW02008465 OWR53319.1 KQ460880 KPJ11511.1 GEDC01024700 GEDC01014714 JAS12598.1 JAS22584.1 KQ971312 KYB29262.1 GBYB01005881 JAG75648.1 KQ458761 KPJ05115.1 GBYB01005882 JAG75649.1 CP026244 AWO98297.1

Proteomes

UP000005204 UP000218220 UP000007151 UP000053240 UP000007266 UP000053268 + More
UP000246464 UP000005226

PRIDE

H9JP79 U3N2H7

Pfam

PF02201 SWIB

Interpro

IPR013083   Znf_RING/FYVE/PHD        + More
IPR036443   Znf_RanBP2_sf
IPR016495   p53_neg-reg_MDM_2/4
IPR001876   Znf_RanBP2
IPR015459   MDM2_E3_ligase
IPR001841   Znf_RING
IPR036885   SWIB_MDM2_dom_sf
IPR003121   SWIB_MDM2_domain

SUPFAM

SSF90209 SSF90209 + More
SSF47592 SSF47592

Gene 3D

3.30.40.10 1.10.245.10

ProteinModelPortal

H9JP79 U3N2H7 A0A2A4JJ97 A0A2A4JJS1 A0A2H1WUF3 A0A1E1WHW1 + More
A0A212FHV9 A0A0N1ICZ6 A0A1B6CGP3 A0A139WMU9 A0A0C9RFT5 A0A194QJM5 A0A0C9QYX6 A0A2U9B352 H2T886

PDB

5MNJ E-value=5.32393e-07, Score=127

KEGG

101745393 K06643 E3 ubiquitin-protein ligase Mdm2 [EC:2.3.2.27] | (RefSeq) E3 ubiquitin-protein ligase Mdm2-li

PATHWAY

04068    FoxO signaling pathway - Bombyx mori (domestic silkworm)
04120    Ubiquitin mediated proteolysis - Bombyx mori (domestic silkworm)
04144    Endocytosis - Bombyx mori (domestic silkworm)

GO

GO:0016567 GO:0000122 GO:0043066 GO:0046872 GO:0005634 GO:0016874 GO:0071157 GO:0008270 GO:0003735 GO:0005840 GO:0006412 GO:0004888 GO:0007166 GO:0016020 GO:0004713 GO:0016491 GO:0015930

PANTHER

PTHR13844:SF15

Length:

332

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.0255

Exp number, first 60 AAs:

0

Total prob of N-in:

0.03290

outside

1 - 332

Pi

202.240202

Theta

178.169932

Tajima's D

0.296282

CLR

0.820865

CSRT

0.452777361131943

Interpretation

Uncertain

Sequence

Summary

Ontologies

Topology

Population Genetic Test Statistics