Gene

KWMTBOMO13954

Pre Gene Modal

BGIBMGA011319

Annotation

PREDICTED:_integrator_complex_subunit_7_[Bombyx_mori]

Location

Bomo_Chr23(+):14653688-14659462      View in EpiBrowser

Full name

Integrator complex subunit 7      

Location in the cell

Mitochondrial   Reliability : 1.641

CDS

ATGATTGGTGTTAAAATGAATACATTCAACGACAATTCGGCGGAGCCTGAACAAGATGCAAATTCAGCATTGACCGAGCTCGATAAAGGCCTACGGTCGTGCAAAGTAGGAGAGCAATGTGAAGCCATCGTCCGGTTCCCTCGTCTTTTCGAAAAATATCCTTTCCCTATATTAATTAATTCATCTTTTCTTAAATTGTCTGACGTTTTTCGTATGGGTAACAATTTTTTGAGACTCTGGGTTTTGAGAGTCTGTCAACAAAGCGAAAAGCACCTAGATAAGATTCTGAACGTAGACGAGTTCTTAAGGAGGATCTTTAGTGTTCTACACTCAAACGATCCGGTGGCTAGGGCTCTCGCTCTGAGAACGCTTGGTGCAGTAGCAGGTATTATCCCAGAGCGCCAGAATGTACATCACGCAATCCGAAGGGGCTTGGATAGCCATGACAATGTTGAAGTTGATGCTGCTATATATGCTACTACTAGATTTGCTGCCCACTCCAATTCATTCGCAGTAGCCATGTGCAATAAGCTATCAGATATGGTGGAAAGTGAGGGCACTGCTGCTGAGAGACGAGCAAAACTTGTCAGAGCCCTGAGGACCGTTCATGGTGGAGCAATCAGAGCACAAGGAGTTTTGAAATTATTGAGATCATTGTTAGACAAGTTTCCTTCGTCAAGTTCGGTGCGAGCTTCAATCACTGCACTCACACATATAGCTTCAGATACAGTGGTTCATGTTCCTGATCAGGTTGAACTACTGCTAAATATAGCCATGAATGACGCCCGATCAGCCGTACGTCGTTCCGCACTGCTTGGCCTCAAGAAGTTGGCTGAGAATGCAGCTCTCTGGCCCGCACACTGTATACAGAACCTGGTCAGAGCCGCTAGCGATAGTCGAGACACTGACCACACTATGCTGTGCCTTCGAGTAATGCAGATTCTGGTGCAGTGCCCAGCAGTGTGCGCCACGGCAGGGTGTCCTCAGCGCGGCGAGTACAGTGCCCTGAGGCAGTACTGCAGTGAAGCCGCTCTCAGTGCTGACTTGAAGCAAGCCGCAACCGCTGCGGATGTCCTCACCAGGATCGTTGTTCATTGCTATGAAGAATGTCTTCCGGTGGAAGGTTCAGATCTGATGCTGGCTCTGGAGTCCCTGGTGATAGCGGCAGGGGCTGATAATGGGCAGAATATAAAGTCACTCAGGGTTGCGCTTAGGTGTTTGGTCCAGCTGAGCACTGCAGAACCCACAGTTTACGCTCCACGGACGGCATCGGTGCTTGCTGGACAACTGGCTACCAGTAGCTGGGCCAACCCTGGCCCGAGGGAGGCCTCGATCCTGGAAGCCCTGGGCGCGTTAGGTGGTGGAACCTACTGTCCCATGTCGGTGGCACCAGCGTTGCCCGCACTGCATCAAGCGTTGGAAGCCATGCAGAGAGAAAATGCGATAGCAAATCCGTCAGACGAAGGTAACGCTCTGGTGCTTCTCTGCACGGTGCTTTTCCAAGAACGGGCCGGGAAAGCGTTGACCTTTACCATCAGCAACGACTGGTGCACGAAGATCTTGGACGCGGTCCAAGTGGCTGACGGTTGGGTGCGATACAGAGTCGCCAGGGCCGCCTTGAGGTACGGGCATCACCACCTGGCCGCGGAGCTGCTGGTCCGGCTGGCGGCGCAGGCCCCCAGCGAGGCGGCTCAGCGCTGGCTGGCGGCGCTGCACCGGGCCGCCGCCGCCGACGCCAAGCTCGCCATCGACGGTAACGAGCTTATGTATATTATCCGTACACGCAGACAACTAGCGGACTAA

Protein

MIGVKMNTFNDNSAEPEQDANSALTELDKGLRSCKVGEQCEAIVRFPRLFEKYPFPILINSSFLKLSDVFRMGNNFLRLWVLRVCQQSEKHLDKILNVDEFLRRIFSVLHSNDPVARALALRTLGAVAGIIPERQNVHHAIRRGLDSHDNVEVDAAIYATTRFAAHSNSFAVAMCNKLSDMVESEGTAAERRAKLVRALRTVHGGAIRAQGVLKLLRSLLDKFPSSSSVRASITALTHIASDTVVHVPDQVELLLNIAMNDARSAVRRSALLGLKKLAENAALWPAHCIQNLVRAASDSRDTDHTMLCLRVMQILVQCPAVCATAGCPQRGEYSALRQYCSEAALSADLKQAATAADVLTRIVVHCYEECLPVEGSDLMLALESLVIAAGADNGQNIKSLRVALRCLVQLSTAEPTVYAPRTASVLAGQLATSSWANPGPREASILEALGALGGGTYCPMSVAPALPALHQALEAMQRENAIANPSDEGNALVLLCTVLFQERAGKALTFTISNDWCTKILDAVQVADGWVRYRVARAALRYGHHHLAAELLVRLAAQAPSEAAQRWLAALHRAAAADAKLAIDGNELMYIIRTRRQLAD

Description

Component of the Integrator complex, a complex involved in the small nuclear RNAs (snRNA) U1 and U2 transcription and in their 3'-box-dependent processing. May play a role in DNA damage response (DDR) signaling during the S phase.

Subunit

Belongs to the multiprotein complex Integrator.

Similarity

Belongs to the Integrator subunit 7 family.

Keywords

Chromosome   Complete proteome   DNA damage   Nucleus   Reference proteome  

Feature

chain  Integrator complex subunit 7

Uniprot

H9JP65   A0A437BHS9   A0A2A4K3G7   A0A2A4K2F8   A0A2H1WHS8   L7X0U3   + More
C3PPH1   A0A212FCZ7   A0A194RED4   A0A194QIC2   A0A2J7QT39   A0A1Y1NF75   A0A0L7QRY9   A0A0N0BFT0   E2ACI1   A0A151WNM2   A0A154P6S6   A0A088ALP4   A0A2A3ES99   A0A158N920   E0VNN0   E2BBN0   A0A0A9W714   A0A026W7V3   A0A146KV74   A0A151J7N6   N6TTR7   A0A195FU03   F4WHI4   T1H929   A0A151I6Y2   A0A195BVR4   A0A023EXU1   D6W9C5   A0A1B6HNP3   A0A139WMM3   A0A232F331   A0A1B6DJT3   K7J5H3   A0A0L0BTF0   A0A182HNR4   A0A1I8Q617   A0A182PUS5   A0A1I8NII0   A0A182SHY3   A0A1S4H6J2   Q7PMY5   A0A182LPS7   A0A182TQH5   A0A1Q3G3H8   A0A182YD83   A0A182KC86   A0A182XEB8   A0A182UWD8   A0A182Q2U1   A0A182RQT5   A0A182MBG1   A0A182MY85   A0A2G9P923   A0A182WG16   A0A336MZS9   A0A336MB09   J9JLK9   A0A1B0AR59   A0A084WB03   A0A1A9XGS7   W5JMI8   H0YY53   K7FYG8   U3KD91   A0A452HS34   A0A3L8SQV3   A0A151P3K7   A0A1U7SBD5   G1KFM6   A0A151P3Y6   A0A226MUR7   A0A151P3T9   G1NBV1   Q5ZL91   A0A226NY60   A0A0P5P4V4   A0A093QKI1   A0A218V3U7   A0A1A9ZG24   A0A091G180   D3DT96   A0A0A1WYV2   A0A2I0US64   A0A182FVR6  

Pubmed

19121390    23674305    22118469    26354079    28004739    20798317    + More
21347285    20566863    25401762    24508170    26823975    23537049    21719571    25474469    18362917    19820115    28648823    20075255    26108605    25315136    12364791    20966253    25244985    24438588    20920257    23761445    20360741    17381049    28562605    30282656    22293439    20838655    15642098    24621616    11181995    25830018   

EMBL

BABH01009595    BABH01009596    RSAL01000054    RVE49984.1    NWSH01000204    PCG78444.1    + More
PCG78445.1    ODYU01008749    SOQ52618.1    KC469894    AGC92734.1    CU681835    CAY54144.1    AGBW02009117    OWR51625.1    KQ460297    KPJ16193.1    KQ458761    KPJ05144.1    NEVH01011202    PNF31746.1    GEZM01005376    JAV96198.1    KQ414775    KOC61271.1    KQ435794    KOX73792.1    GL438528    EFN68847.1    KQ982907    KYQ49464.1    KQ434827    KZC07629.1    KZ288189    PBC34577.1    ADTU01009036    ADTU01009037    DS235341    EEB14986.1    GL447128    EFN86907.1    GBHO01039362    GBHO01039361    GBHO01039360    GBHO01039359    JAG04242.1    JAG04243.1    JAG04244.1    JAG04245.1    KK107372    EZA51721.1    GDHC01019104    GDHC01011811    JAP99524.1    JAQ06818.1    KQ979640    KYN20028.1    APGK01052548    KB741213    ENN72625.1    KQ981268    KYN43938.1    GL888161    EGI66338.1    ACPB03003465    KQ978451    KYM93935.1    KQ976405    KYM91886.1    GBBI01004896    JAC13816.1    KQ971312    EEZ98480.1    GECU01031402    JAS76304.1    KYB29182.1    NNAY01001170    OXU24898.1    GEDC01012572    GEDC01011357    JAS24726.1    JAS25941.1    JRES01001494    KNC22489.1    APCN01001971    AAAB01008966    EAA13050.5    GFDL01000687    JAV34358.1    AXCN02002037    AXCM01001977    KV922615    PIN99400.1    UFQT01003664    SSX35191.1    UFQT01000832    SSX27465.1    ABLF02025798    JXJN01002265    ATLV01022298    KE525331    KFB47397.1    ADMH02000621    ETN65592.1    ABQF01123290    AGCU01167073    AGCU01167074    AGCU01167075    AGCU01167076    AGTO01020510    QUSF01000008    RLW06890.1    AKHW03001146    KYO43638.1    KYO43639.1    MCFN01000449    OXB58749.1    KYO43640.1    AJ719843    AWGT02000284    OXB72434.1    GDIQ01133568    JAL18158.1    KL761277    KFW89066.1    MUZQ01000055    OWK60664.1    KL447600    KFO75106.1    CH471100    EAW93401.1    GBXI01010496    JAD03796.1    KZ505644    PKU48893.1   

Proteomes

UP000005204    UP000283053    UP000218220    UP000007151    UP000053240    UP000053268    + More
UP000235965    UP000053825    UP000053105    UP000000311    UP000075809    UP000076502    UP000005203    UP000242457    UP000005205    UP000009046    UP000008237    UP000053097    UP000078492    UP000019118    UP000078541    UP000007755    UP000015103    UP000078542    UP000078540    UP000007266    UP000215335    UP000002358    UP000037069    UP000075840    UP000095300    UP000075885    UP000095301    UP000075901    UP000007062    UP000075882    UP000075902    UP000076408    UP000075881    UP000076407    UP000075903    UP000075886    UP000075900    UP000075883    UP000075884    UP000075920    UP000007819    UP000092460    UP000030765    UP000092443    UP000000673    UP000007754    UP000007267    UP000016665    UP000291020    UP000276834    UP000050525    UP000189705    UP000001646    UP000198323    UP000001645    UP000000539    UP000198419    UP000053258    UP000197619    UP000092445    UP000053760    UP000069272   

PRIDE

H9JP65    Q5ZL91    D3DT96   

Pfam

PF00787   PX

Interpro

IPR033060   INTS7        + More
IPR016024   ARM-type_fold       
IPR011989   ARM-like       
IPR001611   Leu-rich_rpt       
IPR001683   Phox       
IPR037904   Nischarin_PX       
IPR036871   PX_dom_sf       
IPR032675   LRR_dom_sf       

SUPFAM

SSF48371   SSF48371        + More
SSF64268   SSF64268       

Gene 3D

1.25.10.10     3.30.1520.10     3.80.10.10    

CDD

cd06875  PX_IRAS

ProteinModelPortal

H9JP65   A0A437BHS9   A0A2A4K3G7   A0A2A4K2F8   A0A2H1WHS8   L7X0U3   + More
C3PPH1   A0A212FCZ7   A0A194RED4   A0A194QIC2   A0A2J7QT39   A0A1Y1NF75   A0A0L7QRY9   A0A0N0BFT0   E2ACI1   A0A151WNM2   A0A154P6S6   A0A088ALP4   A0A2A3ES99   A0A158N920   E0VNN0   E2BBN0   A0A0A9W714   A0A026W7V3   A0A146KV74   A0A151J7N6   N6TTR7   A0A195FU03   F4WHI4   T1H929   A0A151I6Y2   A0A195BVR4   A0A023EXU1   D6W9C5   A0A1B6HNP3   A0A139WMM3   A0A232F331   A0A1B6DJT3   K7J5H3   A0A0L0BTF0   A0A182HNR4   A0A1I8Q617   A0A182PUS5   A0A1I8NII0   A0A182SHY3   A0A1S4H6J2   Q7PMY5   A0A182LPS7   A0A182TQH5   A0A1Q3G3H8   A0A182YD83   A0A182KC86   A0A182XEB8   A0A182UWD8   A0A182Q2U1   A0A182RQT5   A0A182MBG1   A0A182MY85   A0A2G9P923   A0A182WG16   A0A336MZS9   A0A336MB09   J9JLK9   A0A1B0AR59   A0A084WB03   A0A1A9XGS7   W5JMI8   H0YY53   K7FYG8   U3KD91   A0A452HS34   A0A3L8SQV3   A0A151P3K7   A0A1U7SBD5   G1KFM6   A0A151P3Y6   A0A226MUR7   A0A151P3T9   G1NBV1   Q5ZL91   A0A226NY60   A0A0P5P4V4   A0A093QKI1   A0A218V3U7   A0A1A9ZG24   A0A091G180   D3DT96   A0A0A1WYV2   A0A2I0US64   A0A182FVR6  

KEGG

101743087    K13144 integrator complex subunit 7 | (RefSeq) integrator complex subunit 7

GO

GO:0016180   GO:0032039   GO:0034472   GO:0005694   GO:0016604   GO:0000077   GO:0005737   GO:0071479   GO:0006974   GO:0035091   GO:0005178   GO:0005488   GO:0004930   GO:0007186   GO:0016021   GO:0004888   GO:0007166   GO:0016020   GO:0004713   GO:0016491   GO:0015930  

PANTHER

PTHR13322  

Subcellular location

Nucleus  
Chromosome  

Length:

600

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.0342

Exp number, first 60 AAs:

0.00389

Total prob of N-in:

0.00196

outside

1  -  600

 

 

Pi

303.976618

Theta

203.47201

Tajima's D

1.447059

CLR

0.200689

CSRT

0.771761411929404

Interpretation

Uncertain