Gene

KWMTBOMO13948

Pre Gene Modal

BGIBMGA011291

Annotation

PREDICTED:_cAMP_and_cAMP-inhibited_cGMP_3'?5'-cyclic_phosphodiesterase_10A-like_[Bombyx_mori]

Location

Bomo_Chr23(-):14374373-14377257      View in EpiBrowser

Full name

Phosphodiesterase      

Location in the cell

Cytoplasmic   Reliability : 1.338 Extracellular   Reliability : 1.753

CDS

ATGAAGCTCCACCTGAAACCCTGTCGGCATGACGTCGAGGAACTGATGGAGACCAACGGCATTCTGCTGCCGCCTAGTAACTTCCGGACTTATGATTACGACATCAGCGAAGGGAACAGGGAGGAGATGGCGGGCCTGGTGTGCTACATGTTCAAGGAGACGTTTGCCGATCGTAATTTCGAGCGACAGCAGCTAGCGGAGTTCGTGTTATCCGTCCTCAGCTGTTACAGGGACAACCCGTACCACAACGCGCAGCACGCCTTCACGTTCACCCACACGATGTTCATGATATTAGTCAACAATACTGGCTACTTTGAGTTCGCTGAAGTGGCGGCCCTAATGATATCGGGTCTCTGTCACGACCTGGACCATCCCGGGTACAACAACAACTTCCTGATGCTCTGCAAGCACCCACTGGCCCTCATGTACAAGACGTCGATACTCGAGAATCATCATTATTTTCTCGCCAAGAAGATCGTTGAGGATAAACAAATATTCAGCAAGTTACCGATAGTCGATCAAGAACGAATATTGGAGGAGATGAAATACGCCATACTGTGCACCGACCTGGCGGTGTACTTCCAGCTGAGGGCGCAGCTGGCGCCGCTCATCGCCGACCAGACCTTCGATTGGAACGACAACCAGCACAGGAAACTACTCAAGGTACACTGCCGACCTTTTCTGCTCTTTGCGAAGTGA

Protein

MKLHLKPCRHDVEELMETNGILLPPSNFRTYDYDISEGNREEMAGLVCYMFKETFADRNFERQQLAEFVLSVLSCYRDNPYHNAQHAFTFTHTMFMILVNNTGYFEFAEVAALMISGLCHDLDHPGYNNNFLMLCKHPLALMYKTSILENHHYFLAKKIVEDKQIFSKLPIVDQERILEEMKYAILCTDLAVYFQLRAQLAPLIADQTFDWNDNQHRKLLKVHCRPFLLFAK

Cofactor

a divalent metal cation

Similarity

Belongs to the cyclic nucleotide phosphodiesterase family.

Uniprot

H9JP37   A0A212F6Z3   A0A2A4K8V9   A0A194QJR4   L7X1I8   A0A2H1W6A6   + More
A0A0L7KN15   A0A139WM40   A0A1B6C6H2   A0A1B6CZB4   A0A1B6HGB4   A0A1B6GPX3   U4TTY5   U4UNK2   A0A1B6F756   A0A139WNG7   A0A1B6HPV1   A0A1B6LGV0   N6UE16   A0A067RGF4   B3RPP8   A0A1Y1KVY5   A0A1L8DL06   T1ID25   A0A0S7H156   A0A069DZ88   A0A224XC52   A0A2J7PWX3   A0A0L8I5L8   A0A1S3NDF0   A0A0P4VS35   A0A1S3NE72   A0A2R7WGW2   A0A0S7GXH9   A0A2P8Y691   A0A1B0CY76   M3ZTL5   A0A023F0G6   A0A1W4WN66   A0A1W4WYY5   A0A1W4WN57   A0A1S3Q7C1   A0A224X8R1   A0A3B5QMD8   A0A0S7H1T1   A0A3B5Q9T3   A0A0R4IJT4   A5PMD9   A0A0V0GAE4   F1QJC2   Q7ZW87   A0A3B5QYP5   A0A2J7PWY0   A0A0P4WRR5   W5K950   A0A2P4T170   A0A3B3RXT8   A0A3B3RX38   A7RVE3   A0A369SEH1   A0A3B3RXA8   T1HID7   A0A3B3XQY9   A0A087YDX5   A0A3B3XQY4   A0A3B3YY50   A0A3P9QJ34   A0A3P9QJZ9   A0A3P9QJ54   A0A2D0QKC9   B3RXL9   A0A315VRF0   A0A3B3V1V5   W6A375   A0A2D0QN85   A0A2D0QKM7   A0A2D0QKY9   A0A3B4DAI9   A0A2J7PWX5   K7E6Z8   A0A2U4CPT5   G3SP09   A0A3B4YNW7   A0A3Q1M418   A0A3B4YP55   F6URL1   K7FFY5   F1SBW6   A0A341CXC5   A0A1A8QT04   A0A2Y9M4C0   A0A1B6CTP1   R7UJM9   A0A2I2UWU4   A0A2Y9M3B8   A0A1Q3FNA8  

EC Number

3.1.4.-

Pubmed

19121390    22118469    26354079    23674305    26227816    18362917    + More
19820115    23537049    24845553    18719581    28004739    26334808    27129103    29403074    23542700    25474469    23594743    25329095    29240929    17615350    30042472    29703783    23127152    18464734    19393038    17381049    23254933    17975172   

EMBL

BABH01009575    AGBW02009949    OWR49512.1    NWSH01000057    PCG80102.1    KQ458761    + More
KPJ05155.1    KC469894    AGC92726.1    ODYU01006306    SOQ48034.1    JTDY01008626    KOB64476.1    KQ971312    KYB29098.1    GEDC01028206    JAS09092.1    GEDC01018499    JAS18799.1    GECU01034004    JAS73702.1    GECZ01005310    JAS64459.1    KB630069    ERL83373.1    KB632376    ERL94053.1    GECZ01023769    JAS46000.1    KQ971311    KYB29482.1    GECU01031007    JAS76699.1    GEBQ01017056    JAT22921.1    APGK01031393    APGK01031394    APGK01031395    APGK01031396    APGK01031397    APGK01031398    APGK01031399    APGK01031400    APGK01031401    APGK01031402    KB740809    ENN78871.1    KK852480    KDR22951.1    DS985242    EDV27675.1    GEZM01075016    JAV64340.1    GFDF01006952    JAV07132.1    ACPB03013655    GBYX01448133    JAO33341.1    GBGD01001065    JAC87824.1    GFTR01006459    JAW09967.1    NEVH01020867    PNF20836.1    KQ416482    KOF96818.1    GDKW01001345    JAI55250.1    KK854805    PTY18892.1    GBYX01448122    JAO33352.1    PYGN01000878    PSN39765.1    AJWK01035539    GBBI01004268    JAC14444.1    GFTR01007679    JAW08747.1    GBYX01448127    JAO33347.1    BX323866    CABZ01035960    CR854838    GECL01001192    JAP04932.1    BC049532    AAH49532.1    PNF20837.1    GDRN01039842    JAI67178.1    PPHD01012981    POI30106.1    DS469543    EDO44626.1    NOWV01000017    RDD45317.1    ACPB03009364    ACPB03009365    AYCK01002113    DS985245    EDV24450.1    NHOQ01001229    PWA25693.1    JT405942    AHI50401.1    PNF20838.1    AGCU01201845    AGCU01201846    AGCU01201847    AGCU01201848    AGCU01201849    AGCU01201850    AEMK02000001    HAEG01014102    SBR96716.1    GEDC01020705    JAS16593.1    AMQN01007429    KB300677    ELU06420.1    AANG04000169    GFDL01005974    JAV29071.1   

Proteomes

UP000005204    UP000007151    UP000218220    UP000053268    UP000037510    UP000007266    + More
UP000030742    UP000019118    UP000027135    UP000009022    UP000015103    UP000235965    UP000053454    UP000087266    UP000245037    UP000092461    UP000002852    UP000192223    UP000000437    UP000018467    UP000261540    UP000001593    UP000253843    UP000261480    UP000028760    UP000242638    UP000221080    UP000261500    UP000261440    UP000002279    UP000245320    UP000007646    UP000261360    UP000009136    UP000007267    UP000008227    UP000252040    UP000248483    UP000014760    UP000011712   

PRIDE

H9JP37    F1SBW6   

Pfam

PF01590   GAF        + More
PF00233   PDEase_I

Interpro

IPR023174   PDEase_CS        + More
IPR003018   GAF       
IPR023088   PDEase       
IPR002073   PDEase_catalytic_dom       
IPR029016   GAF-like_dom_sf       
IPR003607   HD/PDEase_dom       
IPR036971   PDEase_catalytic_dom_sf       

Gene 3D

1.10.1300.10     3.30.450.40    

CDD

cd00077  HDc

ProteinModelPortal

H9JP37   A0A212F6Z3   A0A2A4K8V9   A0A194QJR4   L7X1I8   A0A2H1W6A6   + More
A0A0L7KN15   A0A139WM40   A0A1B6C6H2   A0A1B6CZB4   A0A1B6HGB4   A0A1B6GPX3   U4TTY5   U4UNK2   A0A1B6F756   A0A139WNG7   A0A1B6HPV1   A0A1B6LGV0   N6UE16   A0A067RGF4   B3RPP8   A0A1Y1KVY5   A0A1L8DL06   T1ID25   A0A0S7H156   A0A069DZ88   A0A224XC52   A0A2J7PWX3   A0A0L8I5L8   A0A1S3NDF0   A0A0P4VS35   A0A1S3NE72   A0A2R7WGW2   A0A0S7GXH9   A0A2P8Y691   A0A1B0CY76   M3ZTL5   A0A023F0G6   A0A1W4WN66   A0A1W4WYY5   A0A1W4WN57   A0A1S3Q7C1   A0A224X8R1   A0A3B5QMD8   A0A0S7H1T1   A0A3B5Q9T3   A0A0R4IJT4   A5PMD9   A0A0V0GAE4   F1QJC2   Q7ZW87   A0A3B5QYP5   A0A2J7PWY0   A0A0P4WRR5   W5K950   A0A2P4T170   A0A3B3RXT8   A0A3B3RX38   A7RVE3   A0A369SEH1   A0A3B3RXA8   T1HID7   A0A3B3XQY9   A0A087YDX5   A0A3B3XQY4   A0A3B3YY50   A0A3P9QJ34   A0A3P9QJZ9   A0A3P9QJ54   A0A2D0QKC9   B3RXL9   A0A315VRF0   A0A3B3V1V5   W6A375   A0A2D0QN85   A0A2D0QKM7   A0A2D0QKY9   A0A3B4DAI9   A0A2J7PWX5   K7E6Z8   A0A2U4CPT5   G3SP09   A0A3B4YNW7   A0A3Q1M418   A0A3B4YP55   F6URL1   K7FFY5   F1SBW6   A0A341CXC5   A0A1A8QT04   A0A2Y9M4C0   A0A1B6CTP1   R7UJM9   A0A2I2UWU4   A0A2Y9M3B8   A0A1Q3FNA8  

PDB

3HR1     E-value=3.44835e-33,     Score=351

KEGG

101742652    K18438 cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10 [EC:3.1.4.17 3.1.4.35] | (RefS

GO

GO:0046872   GO:0007165   GO:0004114   GO:0030552   GO:0010754   GO:0004118   GO:0016021   GO:0016787   GO:0010738   GO:0043949   GO:0008081   GO:0006418   GO:0004814   GO:0006420   GO:0004713   GO:0016491   GO:0015930  

Length:

232

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

1.51245

Exp number, first 60 AAs:

0

Total prob of N-in:

0.14086

outside

1  -  232

 

 

Pi

243.580533

Theta

175.755476

Tajima's D

1.757767

CLR

0.384573

CSRT

0.84000799960002

Interpretation

Uncertain