Gene

KWMTBOMO13940

Annotation

reverse_transcriptase_[Bombyx_mori]

Location

Bomo_Chr23(+):14276668-14280045      View in EpiBrowser

Full name

Probable RNA-directed DNA polymerase from transposon BS       + More
Probable RNA-directed DNA polymerase from transposon X-element      
RNA-directed DNA polymerase from mobile element jockey      

Alternative Name

Reverse transcriptase

Location in the cell

Nuclear   Reliability : 1.851 PlasmaMembrane   Reliability : 1.315

CDS

ATGGTCAGGAACGACAGGCTCTCTGCTCGTGGTGGTGGTACCGTCATTTACTATAGAAGAGCCCTGCATTGCGTCCCACTCGATCCTCCCGCGCTCGCTAATATCGAAGCATCAGTGTGCCGAATCTCACTGACGGGACACGCGCCGATCGTTATCGCGTCCGTTTATCTTCCACCGGATAAGATCGTTCTAAGCAGTGATATCGAGGCGCTGCTCGGCATGGGGAGCTCTGTCATTCTGGCGGGCGACCTAAATTGTAAACACATTAGGTGGAACTCACACACCACAACCCCGAATGGCAGGCGGCTTGACGCGTTAGTCGATAATCTCGCCTTCGATATCGTCGCTCCGCTAATCCCGACTCACTACCCGCTAAATATCGCGCATCGCCCGGATATACTCGACATAGCGTTATTAAAAAACGTAACTCTGCGCTTACACTCGATCGAAGTAGTTTCAGAGTTAGATTCAGACCACCGTCCCGTCGTTATGAAGCTCGGTCGCGCTCCCGATTCCGTTCCCGTCACGAGGACTGTGGTGGATTGGCACACGCTGGGCATCAGCCTGGCTGAATCTGATCCACCATCGCTACCGTTTAGCCCGGACTCTACCCCGTCTCCTCAGGATACCGCTGAAGCCATAGACATCTTAACGTCACACATCACCTCGACATTAGATAGGTCATCGAAACAAGTTGTAGCGGAGGACTTCCTTCACCGCTTCAAATTGTCCGACGATATTAGGGAACTCCTTAGAGCTAAGAACGCCTCGATACGCGCCTACGACAGAAGGACTCGCGCCCTCCCAAAGGTCTTACTACCGCTTAGCTCGTACTCTCAAATCGGATACGGTAGTAACTATGCCCCCCTCGTAGGCCCCTCAGGCCGACTCACGGCGTTCGATGATGACGAAAAAGCAGAGCTGCTGGCCGATACATTGCAAACCCAGTGCACGCCCAGCACTCAATCCGTGGACCCTGTGCATGTAGAATTAGTAGACAGTGAGGTAGAACGCAGAGCCTCCTTGCCACCCTCTGATGTGTTACCACCCGTCACCCTGATGGAAGTTAAAGACTTGATCAAAGACCTACGTCCTCGCAAGGCTCCCGGTTCCGACGGTATATCCAACCGCGTTATTAAACTTCTACCCGTCCAACTCATCGTGATGTTGGCATCTATTTTCAATGCCGCTATGGCGAACTGTATCTTTCCCGCGGTGTGGAAAGAAGCGGACGTTATCGGCATACATAAACCCGGTAAACCAAAAAATCATCCGACGAGCTACCGCCCGATTAGCCTCCTCATGTCTCTAGGCAAACTGTATGAGCGTCTGCTCTACAAACGCCTCAGAGACTTCGTCTCATCCAAGGGCATTCTCATCGATGAACAATTCGGATTCCGTACAAATCACTCATGCGTTCAACAGGTGCACCGCCTCACGGAGCACATTCTTGTGGGGCTTAATCGACCAAAACCGTTATACACGGGAGCTCTCTTCTTCGACGTCGCAAAAGCGTTCGACAAAGTCTGGCACAACGGTTTGATTTTCAAACTATTCAACATGGGTGTGCCGGATAGTCTCGTGCTCATCATACGGGACTTTTTGTCGAACCGCTCTTTTCGATATCGAGTCGAGGGAACCCGCTCCTCCCCACGACCTCTCACAGCTGGAGTCCCGCAAGGCTCTGTCCTCTCACCCCTCCTATTTAGCTTATTCGTTAACGATATTCCCCGGTCGCCGCCGACCCATTTAGCTTTATTCGCCGACGACACGACTGTTTACTATTCCAGTAGAAACAAGTCCCTAATCGCGAAGAAGCTTCAGAGCGCAGCCCTAGCCCTAGGACAGTGGTTCCGAAAATGGCGCATAGACATCAACCCAGCGAAAAGTACTGCGGTGCTCTTTCAGAGGGGAAGCTCCACACGGATTTCCTCCCGTATTAGGAGGAGGAATCTCACACCCCCGATTACTCTCTTTAGTCAATCCATACCCTGGGCCAGGAAGGTCAAGTACCTGGGCGTTACCCTGGATGCATCGATGACATTCCGCCCGCATATAAAATCAGTCCGTGACCGTGCCGCGTTTATTCTCGGTAGACTCTACCCCATGATTTGTAAGCGGAGTAAAATGTCCCTTCGGAACAAGGTGACACTTTACAAAACTTGCATAAGGCCCGTCATGACTTACGCGAGTGTGGTGTTCGCTCACGCGGCCCGCACGCACATAGACACCCTTCAATCTCTACAATCCCGCTTTTGCAGGTTAGCCGTCGGAGCTCCGTGGTTCGTGAGGAACGTTGACCTACACGACGACCTGGGCCTCGAATCTATACAGAAATACATGAAGTCAGCGTCGGAACGGTATTTCGATAAGGCTATGCGTCATGATAATCGCCTTATCGTAGCCGCCGCTGACTACTCCCCGAATCCTGATCATGCAGGAGCCAGTCACCGTCGACGCCCTAGACACGTCCTTACGGATCCATCAGATCCAATAACCTTCGCACTAGACGCCTTCAGCTCTAGGAGCAGGCTTAGGGACCTCGGTAACCGTACTCGTCGAACTCGACAAAGAGTTCGCCGTGCAACCTAA

Protein

MVRNDRLSARGGGTVIYYRRALHCVPLDPPALANIEASVCRISLTGHAPIVIASVYLPPDKIVLSSDIEALLGMGSSVILAGDLNCKHIRWNSHTTTPNGRRLDALVDNLAFDIVAPLIPTHYPLNIAHRPDILDIALLKNVTLRLHSIEVVSELDSDHRPVVMKLGRAPDSVPVTRTVVDWHTLGISLAESDPPSLPFSPDSTPSPQDTAEAIDILTSHITSTLDRSSKQVVAEDFLHRFKLSDDIRELLRAKNASIRAYDRRTRALPKVLLPLSSYSQIGYGSNYAPLVGPSGRLTAFDDDEKAELLADTLQTQCTPSTQSVDPVHVELVDSEVERRASLPPSDVLPPVTLMEVKDLIKDLRPRKAPGSDGISNRVIKLLPVQLIVMLASIFNAAMANCIFPAVWKEADVIGIHKPGKPKNHPTSYRPISLLMSLGKLYERLLYKRLRDFVSSKGILIDEQFGFRTNHSCVQQVHRLTEHILVGLNRPKPLYTGALFFDVAKAFDKVWHNGLIFKLFNMGVPDSLVLIIRDFLSNRSFRYRVEGTRSSPRPLTAGVPQGSVLSPLLFSLFVNDIPRSPPTHLALFADDTTVYYSSRNKSLIAKKLQSAALALGQWFRKWRIDINPAKSTAVLFQRGSSTRISSRIRRRNLTPPITLFSQSIPWARKVKYLGVTLDASMTFRPHIKSVRDRAAFILGRLYPMICKRSKMSLRNKVTLYKTCIRPVMTYASVVFAHAARTHIDTLQSLQSRFCRLAVGAPWFVRNVDLHDDLGLESIQKYMKSASERYFDKAMRHDNRLIVAAADYSPNPDHAGASHRRRPRHVLTDPSDPITFALDAFSSRSRLRDLGNRTRRTRQRVRRAT

Catalytic Activity

a 2'-deoxyribonucleoside 5'-triphosphate + DNA(n) = diphosphate + DNA(n+1)

Cofactor

Mg(2+)
Mn(2+)

Miscellaneous

At least 30 copies of X-element are present in the genome and some elements are polymorphic between different strains.
Prefers poly(rC) and poly(rA) as template and activated DNA is not effective.

Keywords

Nucleotidyltransferase   RNA-directed DNA polymerase   Transferase   Transposable element  

Feature

chain  Probable RNA-directed DNA polymerase from transposon BS

Uniprot

Q93137   Q9XXW0   Q9BPQ0   A0A0N1PFV1   O96546   A0A1Y1NA23   + More
V5GNJ2   A0A023EYS8   A0A2S2PPK8   A0A2S2QEE0   X1WNI2   A0A2J7QR37   K7IN67   A0A2J7PU96   J9LC21   A0A2J7QY69   A0A2J7PBY3   A0A224XB44   X1WZH0   A0A023EZE6   A0A2J7R7D0   J9M522   A0A0A9YJ00   A0A2J7Q6J2   A0A2S2N814   A0A2S2Q383   A0A0A9YU04   A0A224X6Q4   A0A2J7PQB5   Q95SX7   A0A224X6U5   A0A2S2NGV8   A0A224XI99   A0A224XJI0   J9KPF1   A0A224X6S1   A0A0J7MYU2   J9LFC9   Q9NBX4   A0A2S2R9D4   A0A224X6T4   A0A2H8TF37   A0A2S2PJG2   J9JS95   A0A2J7QB68   A0A2M4CV52   A0A2J7PVX3   A0A2A4K918   A0A087UGF5   A0A2S2PX53   A0A352X8G4   A0A2M4CV42   A0A1Y1KFR3   A0A224X746   A0A2S2P698   A0A2M4BD67   X1WIX8   A0A2M4BDV6   A0A2S2N6Q7   A0A2J7RE85   A0A2S2NPJ7   A0A023F069   A0A2S2P7B2   A0A2S2Q352   A0A224X6W2   A0A2H8TKI9   A0A2M4BD66   A0A3N5Z7I3   A0A142LX26   A0A2M4BDA5   A0A0V0G5B6   A0A2M4BD62   A0A224X724   A0A2S2PHL7   P21328   J9KLB1   A0A224XIB0   A0A069DZL8   J9KSK5   X1WTA1   A0A069DX78   Q07995   A0A2M4BD83   A0A2S2P6S3   A0A224X6R6  

EC Number

2.7.7.49

Pubmed

10333566    26354079    10380107    28004739    25474469    20075255    + More
25401762    7753626    12537569    11405632    30148503    30086797    25527032    2463954    3040362    1714378    26334808    8387152   

EMBL

U07847    AAA17752.1    AB018558    BAA76304.1    AB055391    BAB21761.1    + More
KQ459265    KPJ02064.1    AF081103    AAC72921.1    GEZM01008457    JAV94772.1    GALX01005299    JAB63167.1    GBBI01004395    JAC14317.1    GGMR01018716    MBY31335.1    GGMS01006359    MBY75562.1    ABLF02008153    ABLF02008462    ABLF02008464    NEVH01011985    PNF31054.1    NEVH01021205    PNF19912.1    ABLF02036316    ABLF02036319    ABLF02048663    ABLF02066977    NEVH01009134    PNF33528.1    NEVH01027074    PNF13841.1    GFTR01008262    JAW08164.1    ABLF02034467    GBBI01004571    JAC14141.1    NEVH01006736    PNF36716.1    ABLF02024246    GBHO01010547    GBHO01010546    JAG33057.1    JAG33058.1    NEVH01017470    PNF24199.1    GGMR01000676    MBY13295.1    GGMS01002992    MBY72195.1    GBHO01021814    GBHO01010549    JAG21790.1    JAG33055.1    GFTR01008279    JAW08147.1    NEVH01022639    PNF18527.1    AY060438    AAL25477.1    GFTR01008251    JAW08175.1    GGMR01003407    MBY16026.1    GFTR01008256    JAW08170.1    GFTR01008257    JAW08169.1    ABLF02041767    GFTR01008271    JAW08155.1    LBMM01013518    KMQ85605.1    ABLF02023911    AF237761    AAF81411.1    GGMS01017365    MBY86568.1    GFTR01008261    JAW08165.1    GFXV01000908    MBW12713.1    GGMR01016905    MBY29524.1    ABLF02028535    ABLF02028545    NEVH01016302    PNF25823.1    GGFL01004957    MBW69135.1    NEVH01020940    PNF20481.1    NWSH01000032    PCG80496.1    KK119692    KFM76444.1    GGMS01000737    MBY69940.1    DNOY01000259    HBE18313.1    GGFL01005012    MBW69190.1    GEZM01084969    JAV60363.1    GFTR01008151    JAW08275.1    GGMR01012305    MBY24924.1    GGFJ01001858    MBW50999.1    ABLF02017874    ABLF02027031    GGFJ01001857    MBW50998.1    GGMR01000226    MBY12845.1    NEVH01005277    PNF39135.1    GGMR01006491    MBY19110.1    GBBI01003810    JAC14902.1    GGMR01012676    MBY25295.1    GGMS01002955    MBY72158.1    GFTR01008260    JAW08166.1    GFXV01002840    MBW14645.1    GGFJ01001844    MBW50985.1    RPOV01000134    RPJ78669.1    KU543673    AMS38352.1    GGFJ01001842    MBW50983.1    GECL01003538    JAP02586.1    GGFJ01001843    MBW50984.1    GFTR01008169    JAW08257.1    GGMR01016296    MBY28915.1    M22874    M38643    ABLF02040174    ABLF02040183    ABLF02055266    GFTR01008246    JAW08180.1    GBGD01000415    JAC88474.1    ABLF02014118    ABLF02014121    ABLF02054790    ABLF02037660    GBGD01000389    JAC88500.1    S59870    AAB26437.2    GGFJ01001822    MBW50963.1    GGMR01012443    MBY25062.1    GFTR01008269    JAW08157.1   

Proteomes

UP000053268    UP000007819    UP000235965    UP000002358    UP000036403    UP000218220    + More
UP000054359   

PRIDE

Q93137    Q9XXW0    Q9BPQ0    Q95SX7    Q9NBX4    P21328    + More

Pfam

PF00078   RVT_1        + More
PF14529   Exo_endo_phos_2
PF07530   PRE_C2HC
PF03372   Exo_endo_phos

Interpro

IPR036691   Endo/exonu/phosph_ase_sf        + More
IPR005135   Endo/exonuclease/phosphatase       
IPR000477   RT_dom       
IPR006579   Pre_C2HC_dom       

SUPFAM

SSF56219   SSF56219       

Gene 3D

3.60.10.10    

ProteinModelPortal

Q93137   Q9XXW0   Q9BPQ0   A0A0N1PFV1   O96546   A0A1Y1NA23   + More
V5GNJ2   A0A023EYS8   A0A2S2PPK8   A0A2S2QEE0   X1WNI2   A0A2J7QR37   K7IN67   A0A2J7PU96   J9LC21   A0A2J7QY69   A0A2J7PBY3   A0A224XB44   X1WZH0   A0A023EZE6   A0A2J7R7D0   J9M522   A0A0A9YJ00   A0A2J7Q6J2   A0A2S2N814   A0A2S2Q383   A0A0A9YU04   A0A224X6Q4   A0A2J7PQB5   Q95SX7   A0A224X6U5   A0A2S2NGV8   A0A224XI99   A0A224XJI0   J9KPF1   A0A224X6S1   A0A0J7MYU2   J9LFC9   Q9NBX4   A0A2S2R9D4   A0A224X6T4   A0A2H8TF37   A0A2S2PJG2   J9JS95   A0A2J7QB68   A0A2M4CV52   A0A2J7PVX3   A0A2A4K918   A0A087UGF5   A0A2S2PX53   A0A352X8G4   A0A2M4CV42   A0A1Y1KFR3   A0A224X746   A0A2S2P698   A0A2M4BD67   X1WIX8   A0A2M4BDV6   A0A2S2N6Q7   A0A2J7RE85   A0A2S2NPJ7   A0A023F069   A0A2S2P7B2   A0A2S2Q352   A0A224X6W2   A0A2H8TKI9   A0A2M4BD66   A0A3N5Z7I3   A0A142LX26   A0A2M4BDA5   A0A0V0G5B6   A0A2M4BD62   A0A224X724   A0A2S2PHL7   P21328   J9KLB1   A0A224XIB0   A0A069DZL8   J9KSK5   X1WTA1   A0A069DX78   Q07995   A0A2M4BD83   A0A2S2P6S3   A0A224X6R6  

KEGG

105842121    no KO assigned | (RefSeq) uncharacterized LOC105842121

GO

GO:0003964   GO:0004519   GO:0006313  

Length:

863

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

3.2566

Exp number, first 60 AAs:

0.05444

Total prob of N-in:

0.05054

outside

1  -  863

 

 

Pi

0

Theta

0

Tajima's D

0

CLR

32.780956

CSRT

0

Interpretation

Uncertain