Gene

KWMTBOMO13884  Validated by peptides from experiments

Pre Gene Modal

BGIBMGA011584

Annotation

iron-sulfur_cluster_assembly_scaffold_protein_IscU_[Papilio_polytes]

Location

Bomo_Chr23(+):12092118-12095351      View in EpiBrowser

Location in the cell

Cytoplasmic   Reliability : 1.827

CDS

ATGGCTTTTTTAATCAACGGAATTCGTCGATGTATGTGTCTTAAAGGCTTTGGAAGTCCTAATGTGATTCTTGCGGCACCTTATCATGCAAACGTCATTGACCATTACGAGAATCCTCGCAATGTTGGTTCATTGGATAAGAAAGATAAAAATGTAGGTACAGGCCTCGTTGGTGCACCTGCATGTGGAGACGTAATGAAGTTGCAAATCAAAGTGGACGAGAATGGAAAAATCGTTGATGCCAAATTTAAAACTTTTGGATGTGGTTCAGCTATAGCTTCAAGCTCTCTTGCCACTGAATGGGTTAAAGGAAAAACAGTTGATGAGGCACTAAAATTGAAGAACACAGATATTGCTAAAGAGCTGTCCTTACCACCAGTCAAGCTTCATTGCTCTATGCTTGCAGAAGACGCAATTAAAGCAGCGTTATCAGATTACAGAATCAAACAACAGACAGAAAATAAGGAGTAA

Protein

MAFLINGIRRCMCLKGFGSPNVILAAPYHANVIDHYENPRNVGSLDKKDKNVGTGLVGAPACGDVMKLQIKVDENGKIVDAKFKTFGCGSAIASSSLATEWVKGKTVDEALKLKNTDIAKELSLPPVKLHCSMLAEDAIKAALSDYRIKQQTENKE

Description

Scaffold protein for the de novo synthesis of iron-sulfur (Fe-S) clusters within mitochondria, which is required for maturation of both mitochondrial and cytoplasmic [2Fe-2S] and [4Fe-4S] proteins.

Similarity

Belongs to the NifU family.

Uniprot

A0A2H1X337   A0A2A4JH15   I4DN15   A0A194PKV7   A0A194RH43   A0A212FB06   + More
H9JPX9   D6WRQ6   A0A1W4WC34   A0A2H8TDT6   A0A2S2NBD4   A0A1Y1LCS5   V4A1W3   A0A151XGK8   A0A0L7LKE2   A0A3Q0IQ16   E2A9A1   A0A151JM64   A0A069DN60   E2BKN3   A0A0V0G3B5   A0A0J7KY26   A0A026WH78   A0A3L8DYX6   E0VHH1   C4WSY8   F4WYL8   W5MB61   A0A0P4VLE0   A0A158P3N1   A0A0C9R1H8   A0A1L8E126   A0A195BZ33   V5IAV0   A0A161MR49   A0A3Q1I3D1   A0A0L0BZX4   A0A164K803   A0A0P5ZND7   A0A0P6E9U9   A0A067RSW7   A0A0P6D0F3   A0A195F0Q6   A0A0K8TPA8   A0A3Q3X4X2   A0A232FE64   A0A023F5R2   A0A3P9H5S8   A0A3Q3AFS8   A0A0P5PNS6   A0A3Q1JD72   A0A0P5K622   A0A3Q3M5G6   A0A3Q3E2I7   J3RZT0   E9HF62   A0A3B4UF13   A0A3B3B7G3   A0A3B3B7D3   K7IMW0   A0A1L8EER9   A0A1Q3FZK3   J3JYL0   A0A3B5A0S4   A0A0B8RRD1   A0A1A9WGZ4   A0A1W7RGH6   A0A0K8RZY9   A0A087XXJ0   A0A3B3V566   W8BV31   A0A0A1XPG1   G3P202   A0A2D4J7N1   A0A1I8PNV3   A0A3P8UDG9   A0A2J7RBW0   A0A3Q1BDQ6   A0A2U9BV36   A0A3N0XHT3   A0A3S2MWA3   A0A2U9CFI1   A0A0P5EAK5   A0A023EGV5   I3K8Q6   A0A023EFH3   T1DKS3   A0A0K8U4Y3   A0A3Q2Y3W2   A0A3Q3JZ98   M4AUT6   A0A3B3XTL2   A0A1A7YPF5   G3P204   A0A3Q2EJ55   D3TNU8   A0A034WN21   B3P1W9   A0A3P8WDZ8   A0A0S7LSK8  

Pubmed

22651552    26354079    22118469    19121390    18362917    19820115    + More
28004739    23254933    26227816    20798317    26334808    24508170    30249741    20566863    21719571    27129103    21347285    26108605    24845553    26369729    28648823    25474469    17554307    23025625    21292972    29451363    20075255    22516182    23537049    25476704    26358130    25727380    24495485    25830018    24945155    26483478    25186727    23758969    23542700    20353571    25348373    17994087    24487278   

EMBL

ODYU01013068    SOQ59741.1    NWSH01001408    PCG71347.1    AK402683    BAM19305.1    + More
KQ459601    KPI94066.1    KQ460205    KPJ17143.1    AGBW02009400    OWR50907.1    BABH01015505    KQ971354    EFA07066.1    GFXV01000458    MBW12263.1    GGMR01001840    MBY14459.1    GEZM01064072    JAV68837.1    KB202953    ESO87291.1    KQ982174    KYQ59350.1    JTDY01000782    KOB75900.1    GL437750    EFN69982.1    KQ978943    KYN27411.1    GBGD01003391    JAC85498.1    GL448819    EFN83731.1    EFN83732.1    GECL01003534    JAP02590.1    LBMM01001979    KMQ95452.1    KK107207    EZA55417.1    QOIP01000002    RLU25644.1    DS235170    EEB12827.1    ABLF02017351    AK340390    BAH71008.1    GL888453    EGI60706.1    AHAT01005112    GDKW01003145    JAI53450.1    ADTU01008278    GBYB01010004    JAG79771.1    GFDF01001812    JAV12272.1    KQ976394    KYM93178.1    GALX01000550    JAB67916.1    GEMB01001882    JAS01289.1    JRES01001097    KNC25536.1    LRGB01003375    KZS03032.1    GDIP01041926    JAM61789.1    GDIQ01065728    JAN29009.1    KK852482    KDR22914.1    GDIQ01085920    JAN08817.1    KQ981880    KYN33946.1    GDAI01001419    JAI16184.1    NNAY01000352    OXU28975.1    GBBI01002198    JAC16514.1    GDIQ01131303    JAL20423.1    GDIQ01190330    JAK61395.1    JU174863    GBEX01001665    AFJ50389.1    JAI12895.1    GL732633    EFX69636.1    GFDG01001655    JAV17144.1    GFDL01002044    JAV33001.1    APGK01025214    BT128339    KB740577    KB631756    AEE63297.1    ENN80191.1    ERL85826.1    GBSH01001386    JAG67640.1    GDAY02001186    JAV50241.1    GBKD01001072    JAG46546.1    AYCK01007730    GAMC01003523    JAC03033.1    GBXI01001495    JAD12797.1    IACK01154259    LAA92467.1    NEVH01005889    PNF38322.1    CP026251    AWP07092.1    RJVU01073043    ROI27803.1    CM012445    RVE68262.1    CP026258    AWP15248.1    GDIP01144813    JAJ78589.1    JXUM01053997    GAPW01005527    KQ561800    JAC08071.1    KXJ77486.1    AERX01032119    GAPW01005526    JAC08072.1    GAAZ01001178    GBKC01001749    JAA96765.1    JAG44321.1    GDHF01031558    GDHF01030904    GDHF01011334    JAI20756.1    JAI21410.1    JAI40980.1    HADX01010295    SBP32527.1    EZ423100    ADD19376.1    GAKP01002894    GAKP01002893    JAC56059.1    CH954181    EDV49857.1    GBYX01151334    JAO92433.1   

Proteomes

UP000218220    UP000053268    UP000053240    UP000007151    UP000005204    UP000007266    + More
UP000192223    UP000030746    UP000075809    UP000037510    UP000079169    UP000000311    UP000078492    UP000008237    UP000036403    UP000053097    UP000279307    UP000009046    UP000007819    UP000007755    UP000018468    UP000005205    UP000078540    UP000265040    UP000037069    UP000076858    UP000027135    UP000078541    UP000261620    UP000215335    UP000265200    UP000264800    UP000261640    UP000261660    UP000000305    UP000261420    UP000261560    UP000002358    UP000019118    UP000030742    UP000261400    UP000091820    UP000028760    UP000261500    UP000007635    UP000095300    UP000265080    UP000235965    UP000257160    UP000246464    UP000069940    UP000249989    UP000005207    UP000264820    UP000261600    UP000002852    UP000261480    UP000265020    UP000008711    UP000265120   

PRIDE

H9JPX9   

Pfam

PF01592   NifU_N

Interpro

IPR002871   NIF_FeS_clus_asmbl_NifU_N        + More
IPR011339   ISC_FeS_clus_asmbl_IscU       

CDD

cd06664  IscU_like

ProteinModelPortal

A0A2H1X337   A0A2A4JH15   I4DN15   A0A194PKV7   A0A194RH43   A0A212FB06   + More
H9JPX9   D6WRQ6   A0A1W4WC34   A0A2H8TDT6   A0A2S2NBD4   A0A1Y1LCS5   V4A1W3   A0A151XGK8   A0A0L7LKE2   A0A3Q0IQ16   E2A9A1   A0A151JM64   A0A069DN60   E2BKN3   A0A0V0G3B5   A0A0J7KY26   A0A026WH78   A0A3L8DYX6   E0VHH1   C4WSY8   F4WYL8   W5MB61   A0A0P4VLE0   A0A158P3N1   A0A0C9R1H8   A0A1L8E126   A0A195BZ33   V5IAV0   A0A161MR49   A0A3Q1I3D1   A0A0L0BZX4   A0A164K803   A0A0P5ZND7   A0A0P6E9U9   A0A067RSW7   A0A0P6D0F3   A0A195F0Q6   A0A0K8TPA8   A0A3Q3X4X2   A0A232FE64   A0A023F5R2   A0A3P9H5S8   A0A3Q3AFS8   A0A0P5PNS6   A0A3Q1JD72   A0A0P5K622   A0A3Q3M5G6   A0A3Q3E2I7   J3RZT0   E9HF62   A0A3B4UF13   A0A3B3B7G3   A0A3B3B7D3   K7IMW0   A0A1L8EER9   A0A1Q3FZK3   J3JYL0   A0A3B5A0S4   A0A0B8RRD1   A0A1A9WGZ4   A0A1W7RGH6   A0A0K8RZY9   A0A087XXJ0   A0A3B3V566   W8BV31   A0A0A1XPG1   G3P202   A0A2D4J7N1   A0A1I8PNV3   A0A3P8UDG9   A0A2J7RBW0   A0A3Q1BDQ6   A0A2U9BV36   A0A3N0XHT3   A0A3S2MWA3   A0A2U9CFI1   A0A0P5EAK5   A0A023EGV5   I3K8Q6   A0A023EFH3   T1DKS3   A0A0K8U4Y3   A0A3Q2Y3W2   A0A3Q3JZ98   M4AUT6   A0A3B3XTL2   A0A1A7YPF5   G3P204   A0A3Q2EJ55   D3TNU8   A0A034WN21   B3P1W9   A0A3P8WDZ8   A0A0S7LSK8  

PDB

6NZU     E-value=2.32912e-57,     Score=557

KEGG

101739286    K22068 iron-sulfur cluster assembly enzyme ISCU, mitochondrial | (RefSeq) iron-sulfur cluster assemb

GO

GO:0016226   GO:0051536   GO:0005506   GO:0051537   GO:0005737   GO:0005759   GO:0006879   GO:0008198   GO:0051539   GO:1990221   GO:0006412   GO:0005515   GO:0005524   GO:0016787   GO:0004713   GO:0016491   GO:0015930  

PANTHER

PTHR10093  

Length:

156

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.03641

Exp number, first 60 AAs:

0.03384

Total prob of N-in:

0.13503

outside

1  -  156

 

 

Pi

278.500341

Theta

212.795665

Tajima's D

0.957608

CLR

0.391835

CSRT

0.64166791660417

Interpretation

Uncertain