Gene

KWMTBOMO13882  Validated by peptides from experiments

Pre Gene Modal

BGIBMGA011438

Annotation

glutathione_peroxidase_[Bombyx_mori]

Location

Bomo_Chr23(-):12070745-12073157      View in EpiBrowser

Full name

Glutathione peroxidase       + More
Epoxide hydrolase      

Location in the cell

Cytoplasmic   Reliability : 2.832

CDS

ATGACATCGAATCCGGATTATAAAGCTGCGACATCCATTCACGAATTTACAGTCAAAAACATTAAAGGTGAAGACGTGAAGCTGGATGTCTACAAAGGCCATGTTTGTATCATTGTGAATGTTGCTTCTCAGTGCGGCCTTACTGCGAACAATTACAAACAATTGAATGAGCTCTATGAACAATACGGAGAGAGCAAAGGTCTCCGCATTCTGGCTTTCCCTTGTAATCAGTTTGCTGGTCAAGAGCCTGGCAATCCAGAAGAGATAGTTTGCTTTGCCTCTGAGCGTAAAGTCAAATTCGATTTGTTTGAGAAAGTTGATGTCAATGGAGACAATGCCAGTCCACTGTGGAAGTATTTGAAGCATAAGCAAGGAGGCACCCTTGGTAGCTTCATCAAGTGGAACTTTACCAAGTTCATCATAAACAAGGATGGAGTTCCAGTTGAACGCCACGGCCCCAATACTGACCCGTTGGATTTGGTCAAATCACTTGAAAAATATTGGTGA

Protein

MTSNPDYKAATSIHEFTVKNIKGEDVKLDVYKGHVCIIVNVASQCGLTANNYKQLNELYEQYGESKGLRILAFPCNQFAGQEPGNPEEIVCFASERKVKFDLFEKVDVNGDNASPLWKYLKHKQGGTLGSFIKWNFTKFIINKDGVPVERHGPNTDPLDLVKSLEKYW

Description

Catalyzes juvenile hormone hydrolysis.

Catalytic Activity

1-(4-methoxyphenyl)-N-methyl-N-[(3-methyloxetan-3-yl)methyl]methanamine + H2O = 2-{[(4-methoxybenzyl)(methyl)amino]methyl}-2-methylpropane-1,3-diol
cis-stilbene oxide + H2O = (1R,2R)-hydrobenzoin

Similarity

Belongs to the glutathione peroxidase family.
Belongs to the peptidase S33 family.

Feature

chain  Glutathione peroxidase

Uniprot

Q4H1F9   A0A088MG62   A0A2H1X308   A0A2A4JGZ0   H9BEW1   A0A2A4JHU3   + More
S4PDQ5   A0A3S2L9A5   A0A0A7BZ16   A0A2Z4N449   A0A194RHV3   A0A194PSG7   I4DLC3   A0A2J7R5F7   A0A2J7R5G6   A0A232FFV5   K7JNW5   A0A067RG32   A0A1L7LQG4   A0A3G6INN4   A0A195BE04   D6WGA1   E2C8G6   Q7YXM2   A0A151XG54   A0A088A7Z8   A0A195CLD7   B1GSA2   A0A151K0F7   V9IF25   D6MT66   E2DTL7   D6WG99   C3VVL8   A0A0C9R9F9   V9IFL3   A0A151JLD5   A0A026W843   E9I8E8   A0A154PNT3   E2A7C1   A0A1W4WYJ8   A0A0L7RBB1   A0A0C9RXB4   A0A0M8ZZC7   A0A1B6MMQ3   J3JU39   A0A1W4WMR2   A0A1Y1LZV2   A0A1Y1LXU9   A0A224XM64   V5YLT2   U5ETL1   V5YML2   A0A0V0G575   J7FQF4   N6TWK5   R4G379   A0A069DPQ5   E0VSA7   A0A1J1J0E1   A0A1B6GFE3   T1IFD9   A0A1B6H3F7   J3JUA0   A0A1B6KHP3   A0A1B6MRQ9   A0A1B6LLR7   A0A1L8E4R6   A0A1B6FCX6   A0A1B0CW59   A0A0L7LKC4   A0A1B6HLI0   A0A0N0PD06   A0A2S2R9A7   V5YNH0   A0A336MDZ9   A0A336M1Z1   A0A336M5U6   A0A336M1R2   A0A0P0ELB6   A0A161MQ76   A0A1V0M8A5   H9JWT0   A0A194PYB3   A0A2H1VS44   A0A2S2PKU2   C6KWM7   A0A2W1BCV7   A0A182N103   A0A1S3CVB6   A0A182QK16   T1E958   A0A1Y1KVB2   A0A1Y1KW73   A0A182YEZ1   A0A088M9L0   A0A182RJ05   A0A1W4WMT2   A0A212FEM4  

EC Number

3.3.2.9

Pubmed

19121390    25191834    23622113    26354079    22651552    28648823    + More
20075255    24845553    26760975    28076409    18362917    19820115    20798317    11932240    16139867    18348209    20226266    24508170    30249741    21282665    22516182    23537049    28004739    26334808    20566863    26227816    26445454    28349297    20622465    28756777    25244985    26385554    22118469   

EMBL

BABH01015503    AB221014    BAE07196.1    KJ995802    AIN39485.1    ODYU01013068    + More
SOQ59740.1    NWSH01001408    PCG71345.1    JQ009330    AFC98365.1    PCG71346.1    GAIX01003566    JAA88994.1    RSAL01000081    RVE48557.1    KC966930    AHV85204.1    MG431818    AWX63641.1    KQ460205    KPJ17142.1    KQ459601    KPI94065.1    AK402091    BAM18713.1    NEVH01006994    PNF36074.1    PNF36072.1    NNAY01000305    OXU29338.1    KK852527    KDR22003.1    FX983171    BAV93789.1    MH024448    AZA04939.1    KQ976513    KYM82400.1    KQ971329    EFA01372.1    GL453666    EFN75696.1    AY329359    AAP93585.1    KQ982179    KYQ59278.1    KQ977642    KYN00899.1    AM492682    CAM34513.1    KQ981298    KYN43069.1    JR040745    AEY59272.1    GQ438844    KZ288203    ADG21870.1    PBC33389.1    GU207870    ACZ66012.1    EFA01370.1    FJ895870    FJ895871    ACP44070.1    GBYB01003426    JAG73193.1    JR040744    AEY59271.1    KQ979014    KYN26619.1    KK107347    QOIP01000007    EZA52230.1    RLU20107.1    GL761538    EFZ23176.1    KQ434977    KZC12880.1    GL437329    EFN70618.1    KQ414617    KOC68154.1    GBYB01012536    JAG82303.1    KQ435793    KOX74205.1    GEBQ01002832    JAT37145.1    APGK01008500    APGK01058242    BT126751    KB741288    KB737708    KB631818    AEE61713.1    ENN70635.1    ENN82954.1    ERL86536.1    GEZM01045098    JAV77920.1    GEZM01045097    JAV77921.1    GFTR01002851    JAW13575.1    AB872500    AB872502    BAO18465.1    GANO01002730    JAB57141.1    AB872501    BAO18464.1    GECL01003013    JAP03111.1    JQ762261    AFP50153.1    APGK01058333    KB632322    ENN70682.1    ERL92328.1    GAHY01001921    JAA75589.1    GBGD01003218    JAC85671.1    DS235748    EEB16263.1    CVRI01000063    CRL04878.1    GECZ01008622    JAS61147.1    ACPB03001635    GECZ01000582    JAS69187.1    BT126813    AEE61775.1    GEBQ01029042    JAT10935.1    GEBQ01027312    GEBQ01001381    JAT12665.1    JAT38596.1    GEBQ01015379    JAT24598.1    GFDF01000549    JAV13535.1    GECZ01021956    GECZ01017483    JAS47813.1    JAS52286.1    AJWK01031790    JTDY01000782    KOB75897.1    GECU01032205    GECU01024988    JAS75501.1    JAS82718.1    KQ460417    KPJ14867.1    GGMS01017321    MBY86524.1    AB872496    AB872499    BAO18461.1    UFQT01000433    SSX24258.1    SSX24255.1    SSX24259.1    SSX24256.1    KT261710    ALJ30250.1    GEMB01002580    JAS00609.1    KU755500    ARD71210.1    BABH01018608    KQ459588    KPI97739.1    ODYU01004100    SOQ43618.1    GGMR01009298    GGMR01017440    MBY21917.1    MBY30059.1    AB293556    BAH97090.1    KZ150476    PZC70740.1    AXCN02001376    GAMD01001627    JAA99963.1    GEZM01076785    JAV63655.1    GEZM01076784    JAV63656.1    KJ579233    AIN34709.1    AGBW02008912    OWR52199.1   

Proteomes

UP000005204    UP000218220    UP000283053    UP000053240    UP000053268    UP000235965    + More
UP000215335    UP000002358    UP000027135    UP000078540    UP000007266    UP000008237    UP000075809    UP000005203    UP000078542    UP000078541    UP000242457    UP000078492    UP000053097    UP000279307    UP000076502    UP000000311    UP000192223    UP000053825    UP000053105    UP000019118    UP000030742    UP000009046    UP000183832    UP000015103    UP000092461    UP000037510    UP000075884    UP000079169    UP000075886    UP000076408    UP000075900    UP000007151   

PRIDE

Q4H1F9    H9JWT0    C6KWM7   

Pfam

PF00255   GSHPx        + More
PF01222   ERG4_ERG24
PF06441   EHN

Interpro

IPR029759   GPX_AS        + More
IPR036249   Thioredoxin-like_sf       
IPR000889   Glutathione_peroxidase       
IPR029760   GPX_CS       
IPR001171   Ergosterol_biosynth_ERG4_ERG24       
IPR010497   Epoxide_hydro_N       
IPR029058   AB_hydrolase       
IPR016292   Epoxide_hydrolase       

SUPFAM

SSF52833   SSF52833        + More
SSF53474   SSF53474       

Gene 3D

3.40.50.1820    

CDD

cd00340  GSH_Peroxidase

ProteinModelPortal

Q4H1F9   A0A088MG62   A0A2H1X308   A0A2A4JGZ0   H9BEW1   A0A2A4JHU3   + More
S4PDQ5   A0A3S2L9A5   A0A0A7BZ16   A0A2Z4N449   A0A194RHV3   A0A194PSG7   I4DLC3   A0A2J7R5F7   A0A2J7R5G6   A0A232FFV5   K7JNW5   A0A067RG32   A0A1L7LQG4   A0A3G6INN4   A0A195BE04   D6WGA1   E2C8G6   Q7YXM2   A0A151XG54   A0A088A7Z8   A0A195CLD7   B1GSA2   A0A151K0F7   V9IF25   D6MT66   E2DTL7   D6WG99   C3VVL8   A0A0C9R9F9   V9IFL3   A0A151JLD5   A0A026W843   E9I8E8   A0A154PNT3   E2A7C1   A0A1W4WYJ8   A0A0L7RBB1   A0A0C9RXB4   A0A0M8ZZC7   A0A1B6MMQ3   J3JU39   A0A1W4WMR2   A0A1Y1LZV2   A0A1Y1LXU9   A0A224XM64   V5YLT2   U5ETL1   V5YML2   A0A0V0G575   J7FQF4   N6TWK5   R4G379   A0A069DPQ5   E0VSA7   A0A1J1J0E1   A0A1B6GFE3   T1IFD9   A0A1B6H3F7   J3JUA0   A0A1B6KHP3   A0A1B6MRQ9   A0A1B6LLR7   A0A1L8E4R6   A0A1B6FCX6   A0A1B0CW59   A0A0L7LKC4   A0A1B6HLI0   A0A0N0PD06   A0A2S2R9A7   V5YNH0   A0A336MDZ9   A0A336M1Z1   A0A336M5U6   A0A336M1R2   A0A0P0ELB6   A0A161MQ76   A0A1V0M8A5   H9JWT0   A0A194PYB3   A0A2H1VS44   A0A2S2PKU2   C6KWM7   A0A2W1BCV7   A0A182N103   A0A1S3CVB6   A0A182QK16   T1E958   A0A1Y1KVB2   A0A1Y1KW73   A0A182YEZ1   A0A088M9L0   A0A182RJ05   A0A1W4WMT2   A0A212FEM4  

PDB

2OBI     E-value=9.79088e-48,     Score=474

KEGG

692548    no KO assigned | (RefSeq) Gpx; glutathione peroxidase

GO

GO:0006979   GO:0004602   GO:0016021   GO:0004601   GO:0016787   GO:0016740   GO:0005789   GO:0019439   GO:0033961   GO:0016925   GO:0006412   GO:0005515   GO:0005524   GO:0004713   GO:0016491   GO:0015930   GO:0055114  

PANTHER

PTHR11592  

Subcellular location

Endoplasmic reticulum membrane  

Length:

168

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.03655

Exp number, first 60 AAs:

0.03581

Total prob of N-in:

0.27477

outside

1  -  168

 

 

Pi

279.696775

Theta

207.585811

Tajima's D

1.092151

CLR

0

CSRT

0.687315634218289

Interpretation

Uncertain