SGID Silkworm Genome Informatics Database
Gene
KWMTBOMO13871
Pre Gene Modal
BGIBMGA011579
Annotation
gustatory_receptor_[Helicoverpa_armigera]
Full name
Gustatory receptor       + More
Gustatory and odorant receptor 22      
Gustatory and odorant receptor 21a      
Location in the cell
PlasmaMembrane   Reliability : 4.916
 

Sequence

CDS
ATGTTCGTGATCTTTCTTAATTTTCAAATCAAGGATATCTACGGACCAGAGATAACGGATAAAGATGGAGCGCTTTTGGATAAGCACGACAGCTTTTATTTGAATACGAAGAGTTTACTTGTACTCTTCCAGATAATGGGTGTGATGCCGATTATGAGAGTTCCAAAAAGTGCTCAAACAACAAGAAGAACAACCTATAATTGGATATCAAAAGCCACTCTGTGGGCTTACTTAGTCTGGGGTCTTGAATGCATTATTGTTGTTAAAGTTGGACAAGAGCGTTTGGCTAACTTCCAGATCGGCTCTAATAAGCGTTTTGATGAGGTTATTTACAACATCATATTTCTGAGTATACTTATACCGCACTTCCTTCTGCCTATCGCTTCTTGGAGGCACGGCCCTCAAGTGGCAATCTTTAAGAATATGTGGACCCACTATCAGTTGAAATACTTAAAGATCACCGGAAAACCCATAGTTTTTCCGAATCTGTACATCTTGACATGGGGTTTGTGTATATTCTCATGGGTTCTAAGCTTCGCAGTCGTGCTGTCGCAGCATTATTTACAAGACGACTTCGAACTATGGCATTCTTTTGCCTACTACCACATCATTGCGATGTTGGATGGATTTTGTTCTCTTTGGTAA
Protein
MFVIFLNFQIKDIYGPEITDKDGALLDKHDSFYLNTKSLLVLFQIMGVMPIMRVPKSAQTTRRTTYNWISKATLWAYLVWGLECIIVVKVGQERLANFQIGSNKRFDEVIYNIIFLSILIPHFLLPIASWRHGPQVAIFKNMWTHYQLKYLKITGKPIVFPNLYILTWGLCIFSWVLSFAVVLSQHYLQDDFELWHSFAYYHIIAMLDGFCSLW

Summary

Description
Gustatory receptor which mediates acceptance or avoidance behavior, depending on its substrates.
Gustatory receptor which mediates acceptance or avoidance behavior, depending on its substrates. GPRgr22 and GPRgr24 together are sufficient for olfactory carbon dioxide-chemosensation.
Gustatory and odorant receptor which mediates acceptance or avoidance behavior, depending on its substrates. Gr21a and Gr63a together are sufficient for carbon dioxide detection and avoidance behavior. It is possible that the CO(2) receptors Gr63a and Gr21a activate the TRPC channels through Galpha49B and Plc21C. This innate olfactory avoidance behavior can be inhibited by inhibitory interactions of the odors such as 1-hexanol and 2,3-butanedione with Gr21a and Gr63a.
Subunit
Gr21a and Gr63a probably form a heterodimer that responds to CO(2).
Similarity
Belongs to the insect chemoreceptor superfamily. Gustatory receptor (GR) family.
Belongs to the insect chemoreceptor superfamily. Gustatory receptor (GR) family. Gr21a subfamily.
Keywords
Behavior   Cell membrane   Complete proteome   Glycoprotein   Membrane   Olfaction   Receptor   Reference proteome   Sensory transduction   Transducer   Transmembrane   Transmembrane helix  
Feature
chain  Gustatory and odorant receptor 22
EMBL
BABH01015478    BABH01015479    ODYU01001951    SOQ38863.1    NWSH01002509    PCG68108.1    + More
KF768713    AIG51907.1    KX585385    ARO70278.1    KY225526    ARO70538.1    KU664806    AMZ01260.1    AGBW02013022    OWR44079.1    JTDY01001430    KOB73874.1    MG546656    AYD42279.1    MG820649    AXF48820.1    RSAL01000081    RVE48553.1    KY283683    AST36342.1    GCVX01000098    JAI18132.1    GDKB01000001    JAP38495.1    KY283762    AST36421.1    DS231934    EDS27619.1    AXCM01000378    AJWK01022645    CH477240    EAT46439.1    DQ989011    AAAB01008980    ABK97612.1    EAA13882.2    APCN01001656    UFQT01001534    SSX30943.1    AXCN02001961    ATLV01016136    KE525057    KFB40998.1    JXJN01006781    KU291872    AOE48122.1    CCAG010023722    JXUM01015690    KQ560437    KXJ82421.1    JQ365177    AFH96948.1    FX985939    BBD43474.1    KP743664    AKI28980.1    ADMH02002089    ETN59386.1    CVRI01000055    CRL01286.1    CH963920    EDW77683.1    CM000157    EDW87177.2    CH933807    EDW13068.1    AE014134    AGB92378.1    CH480829    EDW45437.1    DQ989014    BT025007    CH902620    EDV30784.1    CM002910    KMY87364.1    CM000361    EDX03258.1    CH954177    EDV57268.2    JQ365174    AFH96947.1    JRES01001455    KNC22794.1    CH916368    EDW03447.1    KJ702098    AID61252.1    CH940649    EDW65020.1    OUUW01000004    SPP79745.1    CH379060    EDY70253.1    CH479187    EDW39577.1    CP012523    ALC38447.1    KM251699    AKC58580.2    AM292331    AM292360    CAL23143.2    CAL23172.3    KQ971354    EFA07594.2    UFQS01002860    UFQT01002860    SSX14789.1    SSX34180.1    KQ459601    KPI94062.1    KB466104    RLZ02222.1    KQ460205    KPJ17139.1    CAQQ02391247    GABX01000030    JAA74489.1    KB632188    ERL89794.1    APGK01045842    KB741039    ENN74545.1    KY817104    AVH87320.1    ATLV01013869    KE524905    KFB38231.1    JXUM01055865    KQ561887    KXJ77253.1    APCN01002105   
Pfam
PF08395   7tm_7
Interpro
IPR013604   7TM_chemorcpt       

Ontologies

Topology

Subcellular location
Cell membrane  
Length:
214
Number of predicted TMHs:
4
Exp number of AAs in TMHs:
85.5575
Exp number, first 60 AAs:
16.92192
Total prob of N-in:
0.36583
POSSIBLE N-term signal
sequence
outside
1  -  31
TMhelix
32  -  54
inside
55  -  65
TMhelix
66  -  88
outside
89  -  107
TMhelix
108  -  130
inside
131  -  159
TMhelix
160  -  182
outside
183  -  214
 
 

Population Genetic Test Statistics

Pi
254.584206
Theta
191.91869
Tajima's D
1.03961
CLR
0.091675
CSRT
0.668316584170791
Interpretation
Uncertain
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