Gene

KWMTBOMO13797  Validated by peptides from experiments

Pre Gene Modal

BGIBMGA011542

Annotation

dicer-2_[Bombyx_mori]

Location

Bomo_Chr23(+):9443494-9471298      View in EpiBrowser

Location in the cell

Cytoplasmic   Reliability : 1.633 Nuclear   Reliability : 2.058

CDS

ATGACTACAACAGAAGGAATACAGTATCACGAACAGAAAGCTCGCCCCTATCAAGCAATACTGGAAGAAATAGCAAGTTCAAAAAATACAATAATTCATTTGCCTACTGGTTCTGGAAAAACTTTTATTGCTCAGAGGCTTATAAAAAAGTTCCGTAACCAATTAAAAAAGCCTTGGGGAGAAGGTGGGAAACGCAGTTTCTTTCTTGTAAACACAGTTCCGTTAGTAAATCAACAGAAAAATGTAATTGAAATGATGTGTCCCGTCGACGGTGTTGGTGCCTATAGTAGCGAAGATGGGGTAGACTATTGGAAGAAAGCCGATTGGGACTCTGAATTGGCACGAAACCAGGTAATTGTAATGACCTCTCAGATATTAAGTGACATGCTTACACATGCATATATAAGAATCGAGGATATTAATCTGATTATATTTGATGAATGTCATCATGCTGTGGAAGACCATCCAATGAGAGTTATAATGAAGCACTTTTTGAATTGTAAAGCTCACGAACAGCCCAGAGTTCTAGGTTTAACGGCGACATTATTGAATGGGAATGTATCAATATCTAAGATCGAGGAAACACTTAAGCAGTTGGAAAACACGTTTCATGCAACCATCGCAACTGTTGATGATCTTGGTGAAGTTATGACTTACTCTACCAACCCCCAGGAGTTTATACAGTACTTCAGGAAGCCTCAAATGTCGGAAGCAGCTAAGGAAGCGATAAGTTTACTTAATACGCTACAAAATCTTGTGATGAGTGTTAAGTTGCCTGTCTCTCTGCCATCAAAAGATTTTAAAAAGACACCATGCCAACGAGATATTTCGAACGACCCTAACAAGATTGTGAAGGCGGTAAAAAATCTTATAGTAGGAATGATAACAAATCTCGAAGAGATGGGTTTGTATGGTGGATCTTTGGGTATTCTGGCGTACATTGTCTTGTTAGAAAGATTAAAACGTAAAGCATCAACAAAAGAGGAAAATTTGTTGTATTCAACTGTCATCACCCATTCCACAGAAGCTCGCATGATACTCTTGGACGCCATGGAAAACGAGACTGGGTACGATAAAATAATAAAACATTCATCGGAAAAGATTTTACAATTGATTGACTTGCTGAAGGAATATAACCCTTTGATATTGGAAAAGCCTGGAGAATTGTTGAAAGTAAACCACTCAAGAAAACCTCTCTGTGGAATAATTTTCACGAAACAAAGGTTTACTTCAAAGATTCTGTATAATATCTTAATGGACTTGAAAAAAGCTAGACCGGACGAGTTTGAATTTTTGAAACATGATTTTGTTGTCGGCTTCAGTATCAATCCTTTTAAAAGTACAAGGGAAGAACATTATTTAAAAAAATCATCCCAAAAAGCCATTTTGGGATTTAATAACGGAGACCTGAACTGTTTGATATCGACGAGCGTCATCGAAGAAGGCTTGGACATACCTCAGTGTGCGTTAGTTGTCCGATACGATGCGCCAACCGAATATCGATCTTATATCCAAAGCAAAGGTCGTGCAAGAAGTTCTGAAGCCAGTTTCGTTATACTCGTTGATATTGAAGACAAACAGTCGTTCTTAATAAAATACGACGCGTTCCAAAAAACCGAAGAACGTATTCGTAATCTCATAGTCGGCGATGACAGCCGCGCCGCTCCCACAACTCAAGACATTCATGAGAACTTGTATGATGACGACGAGGTTCCCCCATACGAAACGTCTAATGGCAATATATTATATTCCGTATCAGCAATTAGTTTACTAAGCCGGTATTGCTCGATTTTACCACACGATCAATTCACAACGATCACTCCGGTTTGGTTGCAAGAGGTGGTTGAAAACGGAGCTAAAAAACAGGTCACCGTCATACTTCCCATAGGATCCCCCGTCAAAGAAGAAATTAAGGGTGACCCGTACTCAAATACGAAAACCGCTAAACGCTCCGCTGCACTGAAGGCGTGCATTAAGCTACATGAATTGGGCGAACTTCATCCGTTAACATTACTCCCGTACAAATACGCGGAAGTTGATTACGAACGAGATGACATACGTGGCTGCTTTCCGAACTGGACTAAAGATTGCGAGACCGAGATCAAAGAGAATGTACCCAAGCCTGGTTCCAAGAAACGAAAACGAAAGCATAAAATACAGTTCCCGTCACACCTAGACGCAGTACCAGATAGTTCGGTATTCTATCTTCACGTAATAAAAATGGAGGCGGCATTCGAGAAACCCAACGATAATCGTGAAAAGGCTTTGTACGATTTTATAAAGAGAAACGAATGCTACGGGTTTTTGACGCAGAAGCCTTTGCCTAAACTGTGCGAGTTCCCAGCGTTCACGTCCGTTGGAGAAATCACCACGTCAATAGAAGTCAATTACGCAGTTATAAAACTGACCCCGATTATATTCGAGCTAGTGAAGCAATTCCATTATTTTCTATTCGACCAAATCTTGGCGATCAATAAGAAGTTTCTGATATTCGAGGGAACTAAAAACTGCATGTACGTTGTCCCGGTACTGGAACATAATGGATACAACATTGACTGGGCAACAATGCAGACTCACCACACGGTGCCACCGGTCGCCGCGCCTTCAGTTGAGGAAAGAAAATCGCTGGTAGTCACAGAAGAAAACTACACGAATTGCATTGTAACGCCCTGGTATCGCGGGACTATTCTACCTGAACGGTACGTCGTGACGAAGGTTCTCGAATACATGACGCCGAAATCTCAATTCGATGCTGACTGCTATGAATCGTATGCAAATTATTATGCAAACAACTATAACTTGGATATATTAGGAAGTGAAAGTCAACCACTGTTGGAGGTACGTAACATAAGCACGCGGATGAACTGCCTCCTACCCCGAGCAGCAACGCTCAAAGCGTTCACAGACAAGCAGCTGAAGATGATATCGATTGCGTTCGGCGACGATAAACCGAAGGGATTTGCAGAGATATTTATACCGGAATTCTGCATTAAATACGATTACCCAGGAGTACTGTGGTATAAGGCAACGCTACTGCCCAGTATTATTCACAGAGTTCACATGTTGTTAGTGGCACATGAATTGCTCGTGGAAATATCAAACGCCACTAAATACGGGCAACCAATTTTGAAAAAAACGGAATCATTTCAACCGATACAAGTGGACCGGTATATAGCCATAAATTCATTATTGTCCCAAGTTGAAGAACCACTTCATGTCCACACTATTGACAGAATACACAAAGGCACAGATGATTGTTTGAAGAAAGTTGTACCGTTAAAAAAGAGCTTATATAAACTGCAAAGAAAGAAAATCGACAAAGAGTACCCCTGGGATCAACGAATCGAACCCATCGACGTAGAGCGTAACTTGTCGACCATCACGTTAATGGACATAGAATGTTACGACGAGTTTGTGTCGGCTCCGATATCGTCTGCATCGAACAACCCTTGTTCCCCGCCGAGAATCGTTCCTAAGGCCCCAGCTATAGCACCGCCGCCCATCAAGTACGTTGATAAAATCGAAATATTAAAGAAGACGCCGACCGGGCGAGGTCCGGAACTGAGAGACGTGCTCGCCGCGCTCACCACGATCAACTCAAACGACACCTTCGATCTGGAGCGACCGGAGACACTGGGGGACTCGTTCTTGAAGTTCGCCGCCAGCCTGTACCTGCACCACAAGTTTCCGAACATGAACGAGGGTCAACTAACGAACATCAAGGGCAAGCTGATCAGTAACAGGAATTTATATTACGCTGGTGCGAAATTCAACTTGGGTGGACGCATGAAGGTGGAGCAGTTCAGCCCTAGAAGTGACTTCCTCGTCCCAGGTTTCTTTGCGCCCCCTAAATTGGAAGAATTTATTGAACAAAGACAACCTCGTTTGTATTCCGCGTAG

Protein

MTTTEGIQYHEQKARPYQAILEEIASSKNTIIHLPTGSGKTFIAQRLIKKFRNQLKKPWGEGGKRSFFLVNTVPLVNQQKNVIEMMCPVDGVGAYSSEDGVDYWKKADWDSELARNQVIVMTSQILSDMLTHAYIRIEDINLIIFDECHHAVEDHPMRVIMKHFLNCKAHEQPRVLGLTATLLNGNVSISKIEETLKQLENTFHATIATVDDLGEVMTYSTNPQEFIQYFRKPQMSEAAKEAISLLNTLQNLVMSVKLPVSLPSKDFKKTPCQRDISNDPNKIVKAVKNLIVGMITNLEEMGLYGGSLGILAYIVLLERLKRKASTKEENLLYSTVITHSTEARMILLDAMENETGYDKIIKHSSEKILQLIDLLKEYNPLILEKPGELLKVNHSRKPLCGIIFTKQRFTSKILYNILMDLKKARPDEFEFLKHDFVVGFSINPFKSTREEHYLKKSSQKAILGFNNGDLNCLISTSVIEEGLDIPQCALVVRYDAPTEYRSYIQSKGRARSSEASFVILVDIEDKQSFLIKYDAFQKTEERIRNLIVGDDSRAAPTTQDIHENLYDDDEVPPYETSNGNILYSVSAISLLSRYCSILPHDQFTTITPVWLQEVVENGAKKQVTVILPIGSPVKEEIKGDPYSNTKTAKRSAALKACIKLHELGELHPLTLLPYKYAEVDYERDDIRGCFPNWTKDCETEIKENVPKPGSKKRKRKHKIQFPSHLDAVPDSSVFYLHVIKMEAAFEKPNDNREKALYDFIKRNECYGFLTQKPLPKLCEFPAFTSVGEITTSIEVNYAVIKLTPIIFELVKQFHYFLFDQILAINKKFLIFEGTKNCMYVVPVLEHNGYNIDWATMQTHHTVPPVAAPSVEERKSLVVTEENYTNCIVTPWYRGTILPERYVVTKVLEYMTPKSQFDADCYESYANYYANNYNLDILGSESQPLLEVRNISTRMNCLLPRAATLKAFTDKQLKMISIAFGDDKPKGFAEIFIPEFCIKYDYPGVLWYKATLLPSIIHRVHMLLVAHELLVEISNATKYGQPILKKTESFQPIQVDRYIAINSLLSQVEEPLHVHTIDRIHKGTDDCLKKVVPLKKSLYKLQRKKIDKEYPWDQRIEPIDVERNLSTITLMDIECYDEFVSAPISSASNNPCSPPRIVPKAPAIAPPPIKYVDKIEILKKTPTGRGPELRDVLAALTTINSNDTFDLERPETLGDSFLKFAASLYLHHKFPNMNEGQLTNIKGKLISNRNLYYAGAKFNLGGRMKVEQFSPRSDFLVPGFFAPPKLEEFIEQRQPRLYSA

Similarity

Belongs to the helicase family. Dicer subfamily.

Uniprot

D7UT11   A0A2P1DM58   V9VKP3   A0A2W1BBL1   A0A212EN27   A0A3S2TEC9   + More
A0A0N0P9Y9   A0A2A4J292   A0A194RR37   K0JC91   A0A232F391   K7J5H5   D6WA66   A0A2J7PPP9   A0A2J7PPT2   A0A1W4X5J6   A0A0B5G8Z8   A0A1B6DNE2   A0A386QX51   K9LIV6   A0A2P1DM78   A0A3L8DUT7   A0A0H4SZH3   A0A069DXQ4   A0A1Y1MHP6   A0A154PHY9   A0A023F657   L7Z6F8   A0A195ESA7   A0A151X4G5   A0A2P1DM48   A0A2I6PIZ5   A0A158NDW6   A0A088ABX2   A0A195D7X2   A0A195BR89   A0A0T6B8D4   A0A1B6I9V0   U4UQA5   A0A1B6I6C5   N6UUA9   A0A060H2K4   T1IC52   A0A2R7VQG7   A0A140H4W2   A0A2A3E7Y1   A0A0A7DVT8   A0A0H4T2N5   A0A1B6MLA0   A0A0K8S5D2   A0A0A9YBL6   A0A0A9Y1K7   A0A146M220   A0A1L3A5U6   A0A1Y1MF64   A0A067RAS1   N6TTD5   A0A0C9RZ40   Q174T8   Q49LL4   A0A0M8ZTS6   A0A182PBR4   Q7Q073   A0A182HQ29   A0A1L7NZN0   A0A182KSN9   A0A182XD68   A0A182JTE0   A0A182UVJ5   A0A195C4Z1   A0A026WZU4   A0A182MYJ8   A0A1W7HGU9   W5JN74   A0A182Y1T1   A0A182MEF3   H2BNM7   A0A2J7PPP3   H2BNN1   A0A182HE85   A0A182W963   B0WTP2   A0A1Q3FBT5   A0A182T437   A0A182FU44   A0A1Q3FBL4   H2BNN0   A0A182PZN5   W4VRF8   A0A1W7HGU4   M1G4Y8   A0A2J7PPR2   W5ZSP5   A0A034VRN2   A0A182J388   A0A2H8TDA5   A0A084WHW5   A0A0C9QFQ7  

Pubmed

28756777    22118469    26354079    22562088    28648823    20075255    + More
18362917    19820115    25541004    30261185    30249741    26334808    28004739    25474469    23029445    29267401    21347285    23537049    24391810    26864546    25401762    26823975    24845553    17510324    12364791    28034629    20966253    24508170    20920257    23761445    25244985    26483478    23396108    25348373    24438588   

EMBL

AB566386    BAJ11655.1    MG225431    AVK59442.1    KF717092    AHC98017.1    + More
KZ150192    PZC72388.1    AGBW02013730    OWR42902.1    RSAL01000242    RVE43636.1    KQ459037    KPJ04293.1    NWSH01003946    PCG65644.1    KQ459833    KPJ19859.1    HE647851    CCF23094.1    NNAY01001170    OXU24897.1    KQ971312    EEZ99277.1    NEVH01022647    PNF18314.1    PNF18316.1    KP036490    AJF15703.1    GEDC01010135    JAS27163.1    MH170281    AYE54589.1    JQ037907    AFK73581.1    MG225447    AVK59458.1    QOIP01000004    RLU23508.1    KP230552    AKQ00041.1    GBGD01000076    JAC88813.1    GEZM01034249    JAV83855.1    KQ434899    KZC10938.1    GBBI01002022    JAC16690.1    JX023531    AGE12616.1    KQ981993    KYN30787.1    KQ982548    KYQ55277.1    MG225418    AVK59429.1    MG266019    AUM60046.1    ADTU01013055    KQ981153    KYN08971.1    KQ976424    KYM88476.1    LJIG01009215    KRT83525.1    GECU01024018    JAS83688.1    KB632314    ERL92210.1    GECU01025228    JAS82478.1    APGK01013717    KB739085    ENN82392.1    KF740508    AIC07485.1    ACPB03017886    KK854024    PTY09636.1    KT191018    AMN92163.1    KZ288338    PBC27815.1    KF986375    AIY24625.1    KP230553    AKQ00042.1    GEBQ01003332    JAT36645.1    GBRD01017340    JAG48487.1    GBHO01016669    JAG26935.1    GBHO01016667    JAG26937.1    GDHC01018418    GDHC01005150    JAQ00211.1    JAQ13479.1    KU053335    APF46959.1    GEZM01034723    JAV83648.1    KK852818    KDR15730.1    APGK01019652    KB740115    ENN81333.1    GBYB01013321    GBYB01013322    JAG83088.1    JAG83089.1    CH477406    EAT41563.1    AY713296    AAW48725.1    KQ435851    KOX70787.1    AAAB01008986    EAA00264.4    APCN01003290    LC194137    BAW35366.1    KQ978251    KYM95939.1    KK107054    EZA61552.1    LC194140    BAX36479.1    ADMH02001044    ETN64340.1    AXCM01005461    JF819820    JF819821    AEX31247.1    AEX31248.1    PNF18317.1    JF819824    AEX31250.1    JXUM01035324    JXUM01035325    JXUM01035326    KQ561055    KXJ79846.1    DS232090    EDS34500.1    GFDL01010009    JAV25036.1    GFDL01010095    JAV24950.1    JF819823    AEX31249.1    AXCN02001041    GANO01003802    JAB56069.1    LC194144    BAX36483.1    JX870425    AFZ74931.1    PNF18315.1    KF704245    AHI44612.1    GAKP01013828    JAC45124.1    GFXV01000286    MBW12091.1    ATLV01023892    KE525347    KFB49809.1    GBYB01013323    JAG83090.1   

Proteomes

UP000007151    UP000283053    UP000053268    UP000218220    UP000053240    UP000215335    + More
UP000002358    UP000007266    UP000235965    UP000192223    UP000279307    UP000076502    UP000078541    UP000075809    UP000005205    UP000005203    UP000078492    UP000078540    UP000030742    UP000019118    UP000015103    UP000242457    UP000027135    UP000008820    UP000053105    UP000075885    UP000007062    UP000075840    UP000075882    UP000076407    UP000075881    UP000075903    UP000078542    UP000053097    UP000075884    UP000000673    UP000076408    UP000075883    UP000069940    UP000249989    UP000075920    UP000002320    UP000075901    UP000069272    UP000075886    UP000075880    UP000030765   

PRIDE

D7UT11   

Pfam

PF00636   Ribonuclease_3        + More
PF02170   PAZ
PF00271   Helicase_C
PF03368   Dicer_dimer
PF04851   ResIII
PF00270   DEAD
PF00035   dsrm

Interpro

IPR005034   Dicer_dimerisation_dom        + More
IPR000999   RNase_III_dom       
IPR038248   Dicer_dimer_sf       
IPR006935   Helicase/UvrB_N       
IPR027417   P-loop_NTPase       
IPR003100   PAZ_dom       
IPR014001   Helicase_ATP-bd       
IPR001650   Helicase_C       
IPR011907   RNase_III       
IPR014720   dsRBD_dom       
IPR036389   RNase_III_sf       
IPR036085   PAZ_dom_sf       
IPR011545   DEAD/DEAH_box_helicase_dom       
IPR018247   EF_Hand_1_Ca_BS       

SUPFAM

SSF69065   SSF69065        + More
SSF52540   SSF52540       
SSF101690   SSF101690       

Gene 3D

1.10.1520.10     3.30.160.380    

CDD

cd00079  HELICc
cd00593  RIBOc
cd00048  DSRM

ProteinModelPortal

D7UT11   A0A2P1DM58   V9VKP3   A0A2W1BBL1   A0A212EN27   A0A3S2TEC9   + More
A0A0N0P9Y9   A0A2A4J292   A0A194RR37   K0JC91   A0A232F391   K7J5H5   D6WA66   A0A2J7PPP9   A0A2J7PPT2   A0A1W4X5J6   A0A0B5G8Z8   A0A1B6DNE2   A0A386QX51   K9LIV6   A0A2P1DM78   A0A3L8DUT7   A0A0H4SZH3   A0A069DXQ4   A0A1Y1MHP6   A0A154PHY9   A0A023F657   L7Z6F8   A0A195ESA7   A0A151X4G5   A0A2P1DM48   A0A2I6PIZ5   A0A158NDW6   A0A088ABX2   A0A195D7X2   A0A195BR89   A0A0T6B8D4   A0A1B6I9V0   U4UQA5   A0A1B6I6C5   N6UUA9   A0A060H2K4   T1IC52   A0A2R7VQG7   A0A140H4W2   A0A2A3E7Y1   A0A0A7DVT8   A0A0H4T2N5   A0A1B6MLA0   A0A0K8S5D2   A0A0A9YBL6   A0A0A9Y1K7   A0A146M220   A0A1L3A5U6   A0A1Y1MF64   A0A067RAS1   N6TTD5   A0A0C9RZ40   Q174T8   Q49LL4   A0A0M8ZTS6   A0A182PBR4   Q7Q073   A0A182HQ29   A0A1L7NZN0   A0A182KSN9   A0A182XD68   A0A182JTE0   A0A182UVJ5   A0A195C4Z1   A0A026WZU4   A0A182MYJ8   A0A1W7HGU9   W5JN74   A0A182Y1T1   A0A182MEF3   H2BNM7   A0A2J7PPP3   H2BNN1   A0A182HE85   A0A182W963   B0WTP2   A0A1Q3FBT5   A0A182T437   A0A182FU44   A0A1Q3FBL4   H2BNN0   A0A182PZN5   W4VRF8   A0A1W7HGU4   M1G4Y8   A0A2J7PPR2   W5ZSP5   A0A034VRN2   A0A182J388   A0A2H8TDA5   A0A084WHW5   A0A0C9QFQ7  

PDB

6BUA     E-value=3.32423e-133,     Score=1222

KEGG

100499206    K11592 endoribonuclease Dicer [EC:3.1.26.-] | (RefSeq) dcr-2; dicer-2

GO

GO:0003677   GO:0006396   GO:0003723   GO:0004525   GO:0016075   GO:0005524   GO:0031047   GO:0016021   GO:0016891   GO:0031054   GO:0005634   GO:0005737   GO:0006309   GO:0004530   GO:0030422   GO:0016442   GO:0004386   GO:0005515   GO:0016787   GO:0004713   GO:0016491   GO:0015930  

Length:

1299

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.957499999999998

Exp number, first 60 AAs:

0.00311

Total prob of N-in:

0.04141

outside

1  -  1299

 

 

Pi

244.811009

Theta

175.43466

Tajima's D

1.10558

CLR

0.183903

CSRT

0.687315634218289

Interpretation

Uncertain