Silkworm Genome Informatics Database

Gene

KWMTBOMO13796

Pre Gene Modal

BGIBMGA011469

Annotation

PREDICTED:_PRADC1-like_protein_isoform_X1_[Amyelois_transitella]

Location

Bomo_Chr23(-):9438698-9441493 View in EpiBrowser

Full name

Phosphatidylserine decarboxylase proenzyme, mitochondrial + More
PRADC1-like protein

Alternative Name

PAP21-like protein

Location in the cell

Cytoplasmic Reliability : 2.305

CDS

ATGCCTGGTGCTAATGATCTGCACTTTTATGATGGTTCCTCTACTGCAGATGTCATTGCAGGTGATTTCTTTTTTGAGATAATAGATCCACCGGAACTTGGATACTCATATAGAATAAGACCAGCAAAAGATTTCGGATCTGTATTTAATGAAACCCTACACTTCCACAAGGCTCGTTTAGTACCCACAGTGCCGTTGCATAGTTGTTCTGAGATAATCAACCATGAAGAAATAGTTGGGCACATTGCACTATCTGAGAGAGGAGAATGTTCCTTTGTTTTTAAAGCTACCAAAGCGCAACATGCTGGAGCTAGAGCTGTGATAATTACTGAATCAATTGATAGATGGGATGATTCTTTGGATCACCTTATAGAAATGGTTGATGATAAAATGGAGCTAGACGTAAACATTCCTGCAGCATTCCTTCTCGGCCGCAGTGGAGCCACGATACTGCGTACGCTGAGACGTTTAAAAAGAAAATATGCTATAGTCAATTTACCAGTTAATATGACTCATGTACCAATAAATAAAATGAATCAACCCCCCTGGGTAGCATGGTAA

Protein

MPGANDLHFYDGSSTADVIAGDFFFEIIDPPELGYSYRIRPAKDFGSVFNETLHFHKARLVPTVPLHSCSEIINHEEIVGHIALSERGECSFVFKATKAQHAGARAVIITESIDRWDDSLDHLIEMVDDKMELDVNIPAAFLLGRSGATILRTLRRLKRKYAIVNLPVNMTHVPINKMNQPPWVAW

Description

Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer). Plays a central role in phospholipid metabolism and in the interorganelle trafficking of phosphatidylserine.
May be involved in iversification of muscle cell fates.

Catalytic Activity

1,2-diacyl-sn-glycero-3-phospho-L-serine + H(+) = a 1,2-diacyl-sn-glycero-3-phosphoethanolamine + CO2

Cofactor

pyruvate

Subunit

Heterodimer of a large membrane-associated beta subunit and a small pyruvoyl-containing alpha subunit.

Similarity

Belongs to the phosphatidylserine decarboxylase family. PSD-B subfamily. Eukaryotic type I sub-subfamily.

Keywords

Complete proteome Glycoprotein Reference proteome Secreted Signal

Feature

chain PRADC1-like protein

Uniprot

H9JPL4 A0A2A4J2N0 A0A2A4J2L8 A0A2W1BI05 A0A0N1IN81 A0A1E1WCV8 + More
A0A194RPS6 A0A2H1V3B9 A0A212EN70 A0A3S2NSS9 B0X4Y2 T1E2C8 Q17CW9 A0A1Q3F8H4 W5JDJ3 A0A2M4AXB4 A0A2M4AXD5 A0A182FUI7 T1DRQ0 A0A2M4BZL5 A0A2M4BZP1 A0A2M4C0U5 A0A023EJU8 Q1HQE1 A0A1W4XBQ9 A0A2J7PEB9 A0A2J7PED4 A0A139WNM4 A0A084VKV1 A0A1Y1MX17 A0A2M3ZDT5 A0A2M3ZK06 A0A182VTA1 A0A1L8DPD1 A0A1B0CL84 A0A067RP51 A0A1B6MJ18 A0A182PJK8 A0A1B6JU68 A0A182UUM5 E0VBE6 A0A1B0DAH2 A0A1B6G3J5 A0A182WUS3 A0A3F2YYW7 A0A182LQ13 A0A1I8JT98 A0A1B6MEU9 A0A1W4XBH7 A0A182SLX6 A0A1I8NU65 A0A1I8MAG0 A0A182MYC0 A0A182TQ77 A0A1L8ED86 A0A0A9WSY9 A0A182YA18 A0A182JPX6 A0A182MLT2 A0A182RLR2 D3TP56 W8ALS6 A0A069DWF5 A0A2R7WNB8 A0A1A9UD65 A0A0L0CRM8 Q28WZ6 A0A1B0BVR9 A0A0P4WEF5 B3MEM1 B4LK23 A0A1W4VRQ8 A0A0K8WER8 B4MNM3 A0A0A1XC74 B4HBF1 A0A088AF48 A0A2A3ET69 V9IM66 B4QI36 B4I8E2 A0A034WBA0 A0A0P4VLI3 A0A0B4JCU5 Q9W1W9 B3NNZ1 A0A0U2T948 A0A0V0G403 A0A3B0IYQ8 B4P907 A0A0M8ZWE3 A0A2P2I472 A0A2P8XPI2 A0A0M4EVG5 A0A0L7QYM8 B4J4R3 A0A0K8TLN4 A0A2H8TPX9 B4KM18

EC Number

4.1.1.65

Pubmed

19121390 28756777 26354079 22118469 24330624 17510324 + More
20920257 23761445 24945155 17204158 18362917 19820115 24438588 28004739 24845553 20566863 12364791 20966253 25315136 25401762 26823975 25244985 20353571 24495485 26334808 26108605 15632085 17994087 25830018 22936249 25348373 27129103 10731132 12537568 12537572 12537573 12537574 16110336 17569856 17569867 12537569 14550529 26621068 17550304 29403074 26369729

EMBL

BABH01015299 NWSH01003946 PCG65643.1 PCG65642.1 KZ150192 PZC72390.1 + More
KQ459037 KPJ04292.1 GDQN01006236 JAT84818.1 KQ459833 KPJ19858.1 ODYU01000475 SOQ35327.1 AGBW02013730 OWR42901.1 RSAL01000242 RVE43634.1 DS232359 EDS40597.1 GALA01000849 JAA94003.1 CH477303 EAT44204.1 EJY57531.1 GFDL01011232 JAV23813.1 ADMH02001479 ETN62422.1 GGFK01011917 MBW45238.1 GGFK01011937 MBW45258.1 GAMD01000550 JAB01041.1 GGFJ01009376 MBW58517.1 GGFJ01009372 MBW58513.1 GGFJ01009789 MBW58930.1 GAPW01004273 GEHC01000600 JAC09325.1 JAV47045.1 DQ440503 ABF18536.1 NEVH01026101 PNF14686.1 PNF14687.1 KQ971311 KYB29477.1 ATLV01014308 KE524956 KFB38595.1 GEZM01018502 JAV90183.1 GGFM01005849 MBW26600.1 GGFM01008156 MBW28907.1 GFDF01005762 JAV08322.1 AJWK01017031 KK852508 KDR22400.1 GEBQ01004063 JAT35914.1 GECU01004977 JAT02730.1 DS235028 EEB10702.1 AJVK01029070 GECZ01012886 JAS56883.1 AAAB01008933 APCN01005572 GEBQ01005546 JAT34431.1 GFDG01002260 JAV16539.1 GBHO01032690 GBRD01006558 GDHC01015539 JAG10914.1 JAG59263.1 JAQ03090.1 AXCM01000338 EZ423208 ADD19484.1 GAMC01016840 GAMC01016839 JAB89715.1 GBGD01003225 JAC85664.1 KK855141 PTY21116.1 JRES01000018 KNC34872.1 CM000071 EAL26520.1 JXJN01021454 GDRN01040980 JAI67125.1 CH902619 EDV37641.1 CH940648 EDW60612.1 GDHF01002775 JAI49539.1 CH963848 EDW73712.1 GBXI01005742 JAD08550.1 CH479252 EDW38693.1 KZ288185 PBC34880.1 JR053056 AEY61847.1 CM000362 CM002911 EDX08290.1 KMY95934.1 CH480824 EDW56867.1 GAKP01007537 JAC51415.1 GDKW01003081 JAI53514.1 AE013599 ADV37239.1 AY071051 CH954179 EDV56724.1 KT755414 ALS05248.1 GECL01003337 JAP02787.1 OUUW01000001 SPP73294.1 CM000158 EDW92247.1 KQ435821 KOX72297.1 IACF01003198 LAB68822.1 PYGN01001579 PSN33913.1 CP012524 ALC41862.1 KQ414688 KOC63666.1 CH916367 EDW00609.1 GDAI01002768 JAI14835.1 GFXV01004421 MBW16226.1 CH933808 EDW10807.2

Proteomes

UP000005204 UP000218220 UP000053268 UP000053240 UP000007151 UP000283053 + More
UP000002320 UP000008820 UP000000673 UP000069272 UP000192223 UP000235965 UP000007266 UP000030765 UP000075920 UP000092461 UP000027135 UP000075885 UP000075903 UP000009046 UP000092462 UP000076407 UP000075882 UP000075840 UP000075901 UP000095300 UP000095301 UP000075884 UP000075902 UP000076408 UP000075881 UP000075883 UP000075900 UP000078200 UP000037069 UP000001819 UP000092460 UP000007801 UP000008792 UP000192221 UP000007798 UP000008744 UP000005203 UP000242457 UP000000304 UP000001292 UP000000803 UP000008711 UP000268350 UP000002282 UP000053105 UP000245037 UP000092553 UP000053825 UP000001070 UP000009192

PRIDE

H9JPL4 Q9W1W9

Pfam

PF02225   PA        + More
PF02666   PS_Dcarbxylase
PF01229   Glyco_hydro_39

Interpro

IPR003137   PA_domain        + More
IPR037323   PRADC1-like_PA
IPR003817   PS_Dcarbxylase
IPR033661   PSD_type1_euk
IPR033177   PSD
IPR017853   Glycoside_hydrolase_SF
IPR000514   Glyco_hydro_39
IPR013783   Ig-like_fold

SUPFAM

SSF51445 SSF51445

Gene 3D

2.60.40.10

CDD

cd02127 PA_hPAP21_like

ProteinModelPortal

H9JPL4 A0A2A4J2N0 A0A2A4J2L8 A0A2W1BI05 A0A0N1IN81 A0A1E1WCV8 + More
A0A194RPS6 A0A2H1V3B9 A0A212EN70 A0A3S2NSS9 B0X4Y2 T1E2C8 Q17CW9 A0A1Q3F8H4 W5JDJ3 A0A2M4AXB4 A0A2M4AXD5 A0A182FUI7 T1DRQ0 A0A2M4BZL5 A0A2M4BZP1 A0A2M4C0U5 A0A023EJU8 Q1HQE1 A0A1W4XBQ9 A0A2J7PEB9 A0A2J7PED4 A0A139WNM4 A0A084VKV1 A0A1Y1MX17 A0A2M3ZDT5 A0A2M3ZK06 A0A182VTA1 A0A1L8DPD1 A0A1B0CL84 A0A067RP51 A0A1B6MJ18 A0A182PJK8 A0A1B6JU68 A0A182UUM5 E0VBE6 A0A1B0DAH2 A0A1B6G3J5 A0A182WUS3 A0A3F2YYW7 A0A182LQ13 A0A1I8JT98 A0A1B6MEU9 A0A1W4XBH7 A0A182SLX6 A0A1I8NU65 A0A1I8MAG0 A0A182MYC0 A0A182TQ77 A0A1L8ED86 A0A0A9WSY9 A0A182YA18 A0A182JPX6 A0A182MLT2 A0A182RLR2 D3TP56 W8ALS6 A0A069DWF5 A0A2R7WNB8 A0A1A9UD65 A0A0L0CRM8 Q28WZ6 A0A1B0BVR9 A0A0P4WEF5 B3MEM1 B4LK23 A0A1W4VRQ8 A0A0K8WER8 B4MNM3 A0A0A1XC74 B4HBF1 A0A088AF48 A0A2A3ET69 V9IM66 B4QI36 B4I8E2 A0A034WBA0 A0A0P4VLI3 A0A0B4JCU5 Q9W1W9 B3NNZ1 A0A0U2T948 A0A0V0G403 A0A3B0IYQ8 B4P907 A0A0M8ZWE3 A0A2P2I472 A0A2P8XPI2 A0A0M4EVG5 A0A0L7QYM8 B4J4R3 A0A0K8TLN4 A0A2H8TPX9 B4KM18

KEGG

101746641 no KO assigned | (RefSeq) PRADC1-like protein

GO

GO:0016021 GO:0008233 GO:0016540 GO:0004609 GO:0005739 GO:0006646 GO:0031305 GO:0004553 GO:0005975 GO:0007521 GO:0005576

PANTHER

PTHR10067

Subcellular location

Mitochondrion inner membrane Anchored to the mitochondrial inner membrane through its interaction with the integral membrane beta chain. With evidence from 1 publications.
Secreted

Length:

186

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.18882

Exp number, first 60 AAs:

0.00517

Total prob of N-in:

0.03372

outside

1 - 186

Pi

254.621269

Theta

199.953013

Tajima's D

0.845158

CLR

0.993623

CSRT

0.618569071546423

Interpretation

Uncertain

Sequence

Summary

Ontologies

Topology

Population Genetic Test Statistics