SGID Silkworm Genome Informatics Database
Gene
KWMTBOMO13768  Validated by peptides from experiments
Pre Gene Modal
BGIBMGA011480
Annotation
PREDICTED:_ribonuclease_H2_subunit_A-like_[Plutella_xylostella]
Full name
Ribonuclease      
Location in the cell
Nuclear   Reliability : 1.525
 

Sequence

CDS
ATGAACTCACTACAAGAATTACAGGCAATTATTAAATCCAAAGATAATTTCACTAAATTTGTCATAAATTCTGAAGTACCGGCTGTCTGCAAAAATGAACCTTGCATGCTCGGAGTGGATGAAGCAGGCCGTGGTCCTGTGCTCGGACCTATGGTGTATGGAGTATCCTACTGCCCTCTAAATCGAAAGAGTATTTTGGAGGAATTGGGCTGTGCTGACTCTAAAGCTCTTACGGAAGCTAAAAGGGATGAAATATTCACAAAGATGTTGACTGAGGAAGACAGCCTCAATAATGTTGGCTGGGCTGTTGAAGTCATATCACCTAATTACATTTCCAATTCAATGTACAGACGAGCCAAATGTTCATTAAATGAAGTGTCAATGAATTCTGCAATAGATTTAATTAAGAAAGCTGCAGAAAGTGGTGTCAATATTACAGAAGTTTATGTGGACACAGTGGGGCCTCCAGAGAAATATCAAACAAAATTATCTGAAATATTTCCTTCTTACAAAATAACTGTGGCGAAAAAGGCCGACTCCATCTATCCCATAGTATCAGCAGCAAGTATTGTGGCTAAAGTAACCAGAGATCATGCACTAAAAGTATGGCATTTTAATGAGGGACTACAATTGGATCACACAGAATTTGGCAGTGGATATCCGGGAGATCCATTAACAAAGAAATTCATACGCGATCGAATCGATAACGTTTTTGGATATCCGCTTTTGGTACGGTTCAGCTGGTCGACAGCAGAACTCATGCTGCAAGAGAAAGCGGCAGCGTGCACGTTTGAAGACGTAGACGACCCTGGCAAAGGAAAAATCGCGATCGATGGCGATAACTTCCTTCGGGCGGTAGCTAAATTTACAATCGGCAAAATGTTGTTTCGGTATTGTGCTGCTTTACTGGCGCTCGCCGTTTGCGCCTCCGCGATAGTAGCCCCGAATAACGTTACCAAGACTGATACGCTGAAAGCAGATTCATATTTGGCCGCCTATTCAAAATCACGGATAGAAGCAGAAAAGGCAAAACAAGGCGTTATCATAGTGACCGCGAAAGACGGCGAAAAGAAAATATCGAATCGTGACGACAGTTCGTCTGGATATGATTATTCTCCACCGAGCGACAGTTTCAGTTCATCAGGATCGTCAAGTTTCTCCGGACCATCCAGTTACTCGCCATCTCCGAGTTACGGAACGCCAGTAAAATTCGAACCTGAAATTACCTATGACACTCCCCCTAATACTTATGGCCCTCCGTCCCCTAATTATGGTCCACCAAGCCATTCGTATGGACCTCCGGCACAAACATATGGCCCGCCGGCTCAGACATACGGACCACCGACTCAGTCGTATGGGCCACCGATTTACAAACCCATACTCCCAGTCTACGGACCGCCCCCGAAACCATCTTACGGTGTACCGTATGGCATGGCCGGTTTTAATTTCTTCGACAAACTGTCTTTGAAATTAGACATCCTAACGATTGCAAAGGTGCTCCTCAAATTTCTAATATTCAAGAAGATAGTGACAATGCTGGCTGTAGTTTGTATGTTGCTTGTGATACCAAAGCTAATCAATTTCAAAAAAGACGACGCTGTTAATAAGGATGAAGAGGACCGGAGCTATGGAGCTAGAAACGTGGTGCAGTTAACATCAGCGCAGCAGTTGTTGGAACGCGCAATCCTTGTCTACGGAAGGCAGGAACCTTCGTGTGGCGTTATTTGTCGAATGCGCAGAGTCGTCGACGACATTTACGAATTCCAACCTTATACTAGAAGTAACAATGTTGGCTCGTTGTTGTCATTATAA
Protein
MNSLQELQAIIKSKDNFTKFVINSEVPAVCKNEPCMLGVDEAGRGPVLGPMVYGVSYCPLNRKSILEELGCADSKALTEAKRDEIFTKMLTEEDSLNNVGWAVEVISPNYISNSMYRRAKCSLNEVSMNSAIDLIKKAAESGVNITEVYVDTVGPPEKYQTKLSEIFPSYKITVAKKADSIYPIVSAASIVAKVTRDHALKVWHFNEGLQLDHTEFGSGYPGDPLTKKFIRDRIDNVFGYPLLVRFSWSTAELMLQEKAAACTFEDVDDPGKGKIAIDGDNFLRAVAKFTIGKMLFRYCAALLALAVCASAIVAPNNVTKTDTLKADSYLAAYSKSRIEAEKAKQGVIIVTAKDGEKKISNRDDSSSGYDYSPPSDSFSSSGSSSFSGPSSYSPSPSYGTPVKFEPEITYDTPPNTYGPPSPNYGPPSHSYGPPAQTYGPPAQTYGPPTQSYGPPIYKPILPVYGPPPKPSYGVPYGMAGFNFFDKLSLKLDILTIAKVLLKFLIFKKIVTMLAVVCMLLVIPKLINFKKDDAVNKDEEDRSYGARNVVQLTSAQQLLERAILVYGRQEPSCGVICRMRRVVDDIYEFQPYTRSNNVGSLLSL

Summary

Description
Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
Catalytic Activity
Endonucleolytic cleavage to 5'-phosphomonoester.
Similarity
Belongs to the RNase HII family.
EC Number
3.1.26.4
Pfam
PF01351   RNase_HII
Interpro
IPR036397   RNaseH_sf        + More
IPR023160   RNase_HII_hlx-loop-hlx_cap_dom       
IPR001352   RNase_HII/HIII       
IPR024567   RNase_HII/HIII_dom       
IPR012337   RNaseH-like_sf       
IPR004649   RNase_H2_suA       
SUPFAM
SSF53098   SSF53098       
Gene 3D
PDB
3P5J     E-value=2.93069e-75,     Score=719

Ontologies

Topology

Length:
603
Number of predicted TMHs:
1
Exp number of AAs in TMHs:
36.53703
Exp number, first 60 AAs:
0.00162
Total prob of N-in:
0.08269
outside
1  -  508
TMhelix
509  -  528
inside
529  -  603
 
 

Population Genetic Test Statistics

Pi
164.022316
Theta
174.217825
Tajima's D
-0.888147
CLR
4.469949
CSRT
0.155442227888606
Interpretation
Uncertain
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