Gene

KWMTBOMO13750

Pre Gene Modal

BGIBMGA011490

Annotation

PREDICTED:_DNA_mismatch_repair_protein_Msh2_isoform_X2_[Bombyx_mori]

Location

Bomo_Chr23(-):8311319-8330454      View in EpiBrowser

Full name

DNA mismatch repair protein      

Location in the cell

Cytoplasmic   Reliability : 2.198 Nuclear   Reliability : 1.657

CDS

ATGGGAGTGGAACCTAACCGCCTCGATTACTTAGTACTTTCAAAGGGAAACTTTGAAATTCTCATTAAGAAACTGTTATTGGTGAGACGTTACAGAGTCGAAATATACGTTGCCGATGGATCAATAAAAGGCTGCGATTGGTCACTCAAGTACAAAGGCTCACCGGGATATCTGACGCAATTAGAAGAAGTGCTTGGCGAAGGTTTAGGCGGTTCGGACGAGAACACGCCATGCTTGATGGCGGTTAATATAAAAACCGACCCGGTTTCAAAGGGTAAGCTCCTGGGAGTGGCTTGCGTCGTCGCTGCTGACTATCAAATGTCGGTCTCAGAATTCACCGACGACGATCTGCTGACACAACTTGAAACAATAACCGTCCAAACGGCGCCTTCGGAATGTCTTATACCGTTCTCTGATAATGATGACTACAAAGCTTTGAAGAAAGTAATGGATCGCACCAACGTGACCGTAACGAAACTGAAGAGAGTCGACTTCTCGACCGAAGGTCTCGTGCAGGACCTGAACAGATTGTTAAACTTCAAGGAAGATCAACAGCAGGACGCTAACGCCTTCCCGGAGACGAGGAAAGACTTGGCCATGACTAGTTTAGCGGCCACGATAAAGTACAGTGCTTTACTAAACGAAAGTACGAACTTCGGCAGATTTCGTCTGTCCACAATACGAACGGACTGCTTCCTACACTTGGACGCGGCGGCGCTGACGGCTCTCAACATACTACCGGAGCTGGGCGACAATTCGAACTCGCCTTCTAGAAGCTTGTTCGGTTTACTGGACAGGTGTCGGACTCAGCACGGCAAAAGGTTGCTGGCTCAATGGCTGCGACAGCCGCTCCGCGACATTAACCTAATCAACGAGCGGCTAGACGTTGTGGAACTGCTCATGAACAACTCCCAGCTGAGGCTTCAATTGCACGAGGACCACTTGCGGCGCATACCGGACCTACAGGCCCTGACCAGACGACTGGCCAGAAAGAAAGCTAATTTACATGACTGCTATAAGATATATCAGGCAATCAAGAGGTTACCGTCTTTGTTACAATGTCTGACTGAAGCAGAAAATACGACAGTGCATTCGTCACTCACTGAGCCCATCTCGGAGCTGAACGATGACCTCGACAAGTTCCAGCAAATGATAGAAGCTACACTTGACATGGGTGCTGTAGAAAGAGGCGATTTCCTAGTTAAGCCCTCCTTCGACGAACAACTGCAGAGTCTGAACGAACAACTGGAACGTTTGCAGTCGTCTGCGGAGAGGGAGCTGGGGAAGGCCGCGAGGGACTTGGGACTCGATGCAGGCAAAACTATTAAACTAGAAAATAATACGCAGAATGGATTTTGTTTCAGGATTACTCTGAAAGAAGAACGAAATTTACGAGGCGATAAGAAATATAAAATAATCGACGCCGTCAAAAGCGGTGTTAGATTCAGAACGAATACATTGGAATCAATTAATGAAGAGTACACGCAAGCCAAGACCGACTACGAGAAAGAACAAGATAAAGTCGTTAAAGAAATCGTCAGTATAGCTGGTGGATATTCAGAATGTTTGTTCTGTCTATCTCACATACTGTCGCGTCTAGACGTCTTGGTGTCTTTCGCTGTTGCCGCTTCATCAGCTCCGTACCCGTACTGCAGGCCCGTGGTCACGGAGTCCATCGACGAACTCATCCTGAAGGATGTGAGGCATCCGTGTCTGGAGGTGCAGGAGGGCGTGTCCTATATACCAAACGACGTAGAATTTAAAAGAGGCTCGGTGATGCTGCACATAGTGACCGGCGCGAACATGGGCGGCAAGTCGACGTGGATGCGGTCGGTGGGCGCGAGCGCGGTGCTGGCGCAGGCGGGCTGCCCCGTGCCCGCCGCCGCCGCGCGCCTGCCCCGCCTCGCCGCGCTGTGCGCCCGCATCGGCGCCGCGGACTGCGAGCGCAGGGGACTCAGCACCTTCATGACGGAGATGATCGAGTGTGCCGCCATCCTTAAGACGGCGACACCGAACTCTTTGGTACTAATTGACGAGCTGGGACGGGGTACGTCTACGTATGAAGGCTGCGGCATAGCGTGGGCTATAGCGGAACAATTAGCGAACGAGTGCAAATGTTTCTGTTTGTTCGCGACCCATTATCACGAGTTGACGCGTTTGGCGAGCATTCACCCGAACGTGATAGTGAACTCGCACGCGGCAGCTTCGGTTGTCGATGGACAGCTGGTACTGCTGCACAAGATCCTTCCGGGGCCGGCCGCGCGCTCACTCGGCTTGCACGTCGCCAGGCTCGCCGACCTCCCGGATTCGATTATCGAGTATGCAGAAGCGAAACAAGCGGAGCTAGAAACGAATTTATACGAAGTTGAAGCGGCTATGGAATCGAATGAAACAGCAGAGGGTCAGAAGCTTATTAAAGAATTCTTGAAAAAATGCAAAGAAATTCAAGCATCTGCCAGTAGTGATGATAAAATGATGCAAGAGATCAAGCTTTTAAAACAAGAATTGTTAACTTGTGACAACAAATATGTCCAAACTCTAATATTGTGA

Protein

MGVEPNRLDYLVLSKGNFEILIKKLLLVRRYRVEIYVADGSIKGCDWSLKYKGSPGYLTQLEEVLGEGLGGSDENTPCLMAVNIKTDPVSKGKLLGVACVVAADYQMSVSEFTDDDLLTQLETITVQTAPSECLIPFSDNDDYKALKKVMDRTNVTVTKLKRVDFSTEGLVQDLNRLLNFKEDQQQDANAFPETRKDLAMTSLAATIKYSALLNESTNFGRFRLSTIRTDCFLHLDAAALTALNILPELGDNSNSPSRSLFGLLDRCRTQHGKRLLAQWLRQPLRDINLINERLDVVELLMNNSQLRLQLHEDHLRRIPDLQALTRRLARKKANLHDCYKIYQAIKRLPSLLQCLTEAENTTVHSSLTEPISELNDDLDKFQQMIEATLDMGAVERGDFLVKPSFDEQLQSLNEQLERLQSSAERELGKAARDLGLDAGKTIKLENNTQNGFCFRITLKEERNLRGDKKYKIIDAVKSGVRFRTNTLESINEEYTQAKTDYEKEQDKVVKEIVSIAGGYSECLFCLSHILSRLDVLVSFAVAASSAPYPYCRPVVTESIDELILKDVRHPCLEVQEGVSYIPNDVEFKRGSVMLHIVTGANMGGKSTWMRSVGASAVLAQAGCPVPAAAARLPRLAALCARIGAADCERRGLSTFMTEMIECAAILKTATPNSLVLIDELGRGTSTYEGCGIAWAIAEQLANECKCFCLFATHYHELTRLASIHPNVIVNSHAAASVVDGQLVLLHKILPGPAARSLGLHVARLADLPDSIIEYAEAKQAELETNLYEVEAAMESNETAEGQKLIKEFLKKCKEIQASASSDDKMMQEIKLLKQELLTCDNKYVQTLIL

Description

Component of the post-replicative DNA mismatch repair system (MMR).

Similarity

Belongs to the DNA mismatch repair MutS family.
Belongs to the actin family.

Uniprot

H9JPN5   A0A2A4IYK1   A0A2W1BI74   A0A212FG45   A0A2J7QQ47   A0A2J7QQ55   + More
A0A0L7RBS8   A0A087ZMT5   E2A7C6   A0A2A3E1V0   A0A1B6KJA7   A0A154PGD5   E9J531   A0A291S6W0   A0A2J7QQ67   A0A067QJK6   A0A1B6C2N8   A0A146KK08   A0A0J7L994   A0A1B6EFL7   A0A151IM29   A0A3L8DI31   A0A1B6FWF4   E2C8G1   A0A195BRD0   F4X1S5   A0A195D7Z9   A0A026W837   A0A195ERE7   A0A069DXF4   A0A151X4X9   A0A1Y1KJK4   A0A310SLH7   A0A0L8HX88   W5L927   A0A1W4XGX3   W5UE85   A0A210Q1X3   U5EW91   T1IP55   A0A2T7P402   K7J5F8   F1QEP5   A0A224XJP4   A0A3B4DMJ9   Q803R6   A0A146L782   A0A093GYS9   B2GSY7   Q90XA7   K1Q4X8   G1N0T4   A0A091XIC9   A0A087VC71   A0A091IT29   A0A0T6B8K5   F1NV33   A0A3Q0GQS9   A0A091HD19   Q76FQ4   A0A091Q8J1   A0A087REA1   A0A1V4KDU0   A0A093IHY8   A0A0Q3MHM9   A0A091QH68   A0A091VB76   A0A093NCZ2   R0LY83   A0A151NWV2   R7VRL3   A0A182G5N7   V9KCK0   A0A1S3HMF8   A0A1B0CAD0   A0A2I0LVK5   A0A099Z354   S9WXW1   A0A091VND9   T1IET7   C3XTK2   A0A0D9RM92   A0A093G5M1   A0A093H746   A0A1S3AFR0   A0A0A0A2Z0   A0A3S1BJM4   K7GCJ6   W5NHL1   A0A1A8R4C9   D3K5K3   A0A384ARU3   W5NHL4   A0A1A8C6E5   A0A1A8IAW8   A0A091HJX5   A0A340XLZ3  

Pubmed

19121390    28756777    22118469    20798317    21282665    28992199    + More
24845553    26823975    30249741    21719571    24508170    26334808    28004739    25329095    23127152    28812685    20075255    23594743    15488992    22992520    20838655    15592404    22293439    23371554    26483478    24402279    23149746    18563158    17381049   

EMBL

BABH01015206    BABH01015207    BABH01015208    BABH01015209    NWSH01005465    PCG64193.1    + More
KZ150075    PZC73981.1    AGBW02008723    OWR52693.1    NEVH01012087    PNF30702.1    PNF30703.1    KQ414617    KOC68387.1    GL437329    EFN70623.1    KZ288725    PBC25109.1    GEBQ01028444    JAT11533.1    KQ434899    KZC10857.1    GL768123    EFZ12092.1    MF432996    ATL75347.1    PNF30713.1    KK853270    KDR09158.1    GEDC01029517    JAS07781.1    GDHC01021715    JAP96913.1    LBMM01000177    KMR04605.1    GEDC01000571    JAS36727.1    KQ977074    KYN05940.1    QOIP01000007    RLU20104.1    GECZ01015232    JAS54537.1    GL453666    EFN75691.1    KQ976424    KYM88516.1    GL888551    EGI59582.1    KQ981153    KYN09015.1    KK107347    EZA52225.1    KQ981993    KYN30830.1    GBGD01000383    JAC88506.1    KQ982548    KYQ55320.1    GEZM01084869    JAV60450.1    KQ764145    OAD54587.1    KQ417087    KOF93822.1    JT407546    AHH38022.1    NEDP02005224    OWF42758.1    GANO01001528    JAB58343.1    JH431244    PZQS01000006    PVD28152.1    BX511072    GFTR01008185    JAW08241.1    BC044370    AAH44370.1    GDHC01015184    JAQ03445.1    KK379641    KFV47653.1    BC165693    AAI65693.1    AF412833    AAL04169.1    JH817066    EKC26394.1    KK735175    KFR12901.1    KL487829    KFO10213.1    KK500820    KFP10590.1    LJIG01009134    KRT83688.1    AADN05000006    KL530313    KFO92585.1    AB104853    BAC82442.1    KK690785    KFQ16552.1    KL226333    KFM11805.1    LSYS01003573    OPJ82555.1    KK589524    KFV99226.1    LMAW01002113    KQK81967.1    KK697968    KFQ25551.1    KK422581    KFQ86938.1    KL224621    KFW62051.1    KB742580    EOB06795.1    AKHW03001657    KYO41213.1    KB375593    EMC84169.1    JXUM01044046    JXUM01044047    JXUM01044048    JXUM01044049    JXUM01044050    JXUM01044051    JXUM01044052    KQ561386    KXJ78751.1    JW862948    AFO95465.1    AJWK01003658    AKCR02000082    PKK21451.1    KL887792    KGL75245.1    KB017094    EPY80324.1    KL411166    KFR03948.1    ACPB03001344    GG666463    EEN68628.1    AQIB01038544    AQIB01038545    AQIB01038546    AQIB01038547    AQIB01038548    KL214842    KFV62074.1    KL205829    KFV75245.1    KL870340    KGL87793.1    RQTK01002007    RUS68800.1    AGCU01102692    AGCU01102693    AGCU01102694    AGCU01102695    AHAT01001676    AHAT01001677    AHAT01001678    HAEH01014753    SBS00925.1    GU373681    ADC38881.1    HADZ01010455    SBP74396.1    HAED01008329    SBQ94541.1    KL217566    KFO96608.1   

Proteomes

UP000005204    UP000218220    UP000007151    UP000235965    UP000053825    UP000005203    + More
UP000000311    UP000242457    UP000076502    UP000027135    UP000036403    UP000078542    UP000279307    UP000008237    UP000078540    UP000007755    UP000078492    UP000053097    UP000078541    UP000075809    UP000053454    UP000018467    UP000192223    UP000221080    UP000242188    UP000245119    UP000002358    UP000000437    UP000261440    UP000005408    UP000001645    UP000053605    UP000053119    UP000000539    UP000189705    UP000053286    UP000190648    UP000051836    UP000054081    UP000050525    UP000069940    UP000249989    UP000085678    UP000092461    UP000053872    UP000053641    UP000053283    UP000015103    UP000001554    UP000029965    UP000053875    UP000053584    UP000079721    UP000053858    UP000271974    UP000007267    UP000018468    UP000261681    UP000054308    UP000265300   

PRIDE

H9JPN5    D3K5K3   

Pfam

PF05190   MutS_IV        + More
PF05188   MutS_II
PF01624   MutS_I
PF05192   MutS_III
PF00488   MutS_V
PF00646   F-box
PF00022   Actin
PF00086   Thyroglobulin_1
PF18635   EpCAM_N

Interpro

IPR027417   P-loop_NTPase        + More
IPR007860   DNA_mmatch_repair_MutS_con_dom       
IPR007695   DNA_mismatch_repair_MutS-lik_N       
IPR016151   DNA_mismatch_repair_MutS_N       
IPR036187   DNA_mismatch_repair_MutS_sf       
IPR000432   DNA_mismatch_repair_MutS_C       
IPR036678   MutS_con_dom_sf       
IPR011184   DNA_mismatch_repair_Msh2       
IPR032642   Msh2       
IPR007861   DNA_mismatch_repair_MutS_clamp       
IPR007696   DNA_mismatch_repair_MutS_core       
IPR001810   F-box_dom       
IPR036047   F-box-like_dom_sf       
IPR004000   Actin       
IPR036857   Thyroglobulin_1_sf       
IPR000716   Thyroglobulin_1       
IPR041630   EpCAM_N       

SUPFAM

SSF52540   SSF52540        + More
SSF48334   SSF48334       
SSF53150   SSF53150       
SSF81383   SSF81383       
SSF57610   SSF57610       

Gene 3D

3.30.420.110     3.40.1170.10     4.10.800.10    

CDD

cd00191  TY

ProteinModelPortal

H9JPN5   A0A2A4IYK1   A0A2W1BI74   A0A212FG45   A0A2J7QQ47   A0A2J7QQ55   + More
A0A0L7RBS8   A0A087ZMT5   E2A7C6   A0A2A3E1V0   A0A1B6KJA7   A0A154PGD5   E9J531   A0A291S6W0   A0A2J7QQ67   A0A067QJK6   A0A1B6C2N8   A0A146KK08   A0A0J7L994   A0A1B6EFL7   A0A151IM29   A0A3L8DI31   A0A1B6FWF4   E2C8G1   A0A195BRD0   F4X1S5   A0A195D7Z9   A0A026W837   A0A195ERE7   A0A069DXF4   A0A151X4X9   A0A1Y1KJK4   A0A310SLH7   A0A0L8HX88   W5L927   A0A1W4XGX3   W5UE85   A0A210Q1X3   U5EW91   T1IP55   A0A2T7P402   K7J5F8   F1QEP5   A0A224XJP4   A0A3B4DMJ9   Q803R6   A0A146L782   A0A093GYS9   B2GSY7   Q90XA7   K1Q4X8   G1N0T4   A0A091XIC9   A0A087VC71   A0A091IT29   A0A0T6B8K5   F1NV33   A0A3Q0GQS9   A0A091HD19   Q76FQ4   A0A091Q8J1   A0A087REA1   A0A1V4KDU0   A0A093IHY8   A0A0Q3MHM9   A0A091QH68   A0A091VB76   A0A093NCZ2   R0LY83   A0A151NWV2   R7VRL3   A0A182G5N7   V9KCK0   A0A1S3HMF8   A0A1B0CAD0   A0A2I0LVK5   A0A099Z354   S9WXW1   A0A091VND9   T1IET7   C3XTK2   A0A0D9RM92   A0A093G5M1   A0A093H746   A0A1S3AFR0   A0A0A0A2Z0   A0A3S1BJM4   K7GCJ6   W5NHL1   A0A1A8R4C9   D3K5K3   A0A384ARU3   W5NHL4   A0A1A8C6E5   A0A1A8IAW8   A0A091HJX5   A0A340XLZ3  

PDB

2O8E     E-value=0,     Score=1652

KEGG

101743378    K08735 DNA mismatch repair protein MSH2 | (RefSeq) DNA mismatch repair protein Msh2

PATHWAY

03430    Mismatch repair - Bombyx mori (domestic silkworm)

GO

GO:0032300   GO:0030983   GO:0006298   GO:0005524   GO:0016021   GO:0003677   GO:0000166   GO:0006281   GO:0032301   GO:0043570   GO:0032137   GO:0045910   GO:0032302   GO:0042771   GO:0006310   GO:0002204   GO:0008094   GO:0005634   GO:0000406   GO:0006301   GO:0032405   GO:0043531   GO:0008022   GO:0032143   GO:0042803   GO:0003682   GO:0000400   GO:0008340   GO:0032181   GO:0032142   GO:0048298   GO:0019237   GO:0071168   GO:0051096   GO:0030183   GO:0016887   GO:0007050   GO:0006119   GO:0007281   GO:0000287   GO:0008584   GO:0010224   GO:0043524   GO:0016446   GO:0048304   GO:0031573   GO:0032357   GO:0006302   GO:0003697   GO:0019901   GO:0045190   GO:0010165   GO:0001701   GO:0005515   GO:0016620   GO:0016787   GO:0003676   GO:0016491   GO:0015930  

PANTHER

PTHR11361:SF35  

Subcellular location

Nucleus  

Length:

849

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.00724

Exp number, first 60 AAs:

0.00022

Total prob of N-in:

0.00018

outside

1  -  849

 

 

Pi

267.789189

Theta

163.746279

Tajima's D

1.814117

CLR

0.498856

CSRT

0.851957402129893

Interpretation

Uncertain