Gene

KWMTBOMO13728  Validated by peptides from experiments

Pre Gene Modal

BGIBMGA011511

Annotation

PREDICTED:_cullin-5_[Papilio_machaon]

Location

Bomo_Chr23(+):7703285-7708484      View in EpiBrowser

Location in the cell

Cytoplasmic   Reliability : 2.489 Nuclear   Reliability : 1.904

CDS

ATGCTTAAGGAAAAAGGACAGATCACTTTTGAGGACAAATGGCCATCAATGCGTCCTATAGTTTTAAAGCTATTAAAGCAAGAGACTGTTACACAAACCGAATGGCAAGATCTTTTTGGTGCAGTACATTCAGTATGTTTGTGGGATGAGAGAGGACCGTACAAATTAAGAGACTCGCTTCAACAAGATATTACAATGTACATAAAACAAGCCCAAGTTCGCGTTTTAGCTCAACGGGAAGATCAAGCACTCTTGAAAGCCTATATTGCGGATTCACAGAAAAAGAATAACAATAACAACATTGAAGATAGTTTAGTACGGAAACTAATGTTGGATTCATGGAATCAAAGTATCTTTGTGGATATCAAGGAGAGATTACAGGACTCTGCAATGAAACTTGTACAAGCTGAAAGAAATGGTGAATCATTTGATTCTCAGCTTGTAATAGGAGTAAGAGAGTCATATGTTAATTTGTGCTCAAACACAATAGATAAATTGCAAATCTACAGAGAGAATTTTGAAGCTGCATATATGCAAGCCACAGAAGAATTTTATAAATTGAAAGCAAGTGAACATTTGCTTGCCAATGGAGTTCAGTCATATATGAAGTATGCTGATCAACGTCTCAAAGAAGAAGAGGCTCGTGCTCACCGATATTTGGAGCCAGGAAGTGGTAGTGTAGCTGCATTAACTCAATGTTGTGAAAGAGTACTTATTGGAGAGCATCTTCCAACACTTTTAGCTGAAAGTGCTACATTGATTAAAGCTGGTGAGACAGAAAAGTTGCAACTTATGTTTCGTTTATTGGATAGGGTCCCAGAAGGAGTCGTGCCGATATTGAGAGATTTAGAAGCCCATATAGTATCTGCAGGCTTAGCTGACATGGTTGCATCAGCAGATATCATAACAACAGACTCTGAAAAGTATGTAGAGCGTTTGTTGGATTTATTCAGAAAATTTAGTATGTTAGTTAAAGATGCCTTCTTGGATGATCCAAGGTTTTTAACTGCCAGGGACAAGGCCTATAAATGCGTGGTAAATGATACAACTGTTTTTAAACTTGAGTTGCCTTCATCAACTCTTGCCCGTGGTAGTAAAGGTACAGCTCCTGAAAGCAAGTGCCCTGAACTTCTCGCTAACTATTGTGATATGTTATTACGAAAAACACCGCTAAGTAAAAGATTAACTAGTGAACAGATAGAAATAAGATTAAGAGACGTTTTGTTAGTTTTGAAATATATTGAAAACAAAGATGTATTTATGAGGTATCATAAGGTTCATTTAACAAGAAGATTGATATTAGACTCAAGTGCGGACTCTGAAAAAGAAGAGGATATGGTAGAGTGGTTACGTGAAGTAGGTATGCCTGCAGACTATGTAAATAAATTAGCACGAATGTTTCAAGATGTAAAAGTAAGTGAGGATCTGAATACACAATTTAGGGCAGACACAACTCGTCATGATGCCATCAATATTAAAATACTCAATGCTGGAGCTTGGGCCCGTGGATCTGAAAGAGTAACAGTAAGTCTGCCACTAGAATTAGAAGACTATATTCCTGAAGTTGAAGAGTTTTATAAAAAAAAGCATTCAGGTAGAAAATTGCAGTGGTATCATCACATGAGCAATGGCACTATAACATTTGCTAATTCAGTAGGTCGTTTTGACTTGGATGTTACAACTTTTCAAATGGCAGTGCTATTTGCATGGAATCAAAGACCTATGGAAAAAATAAGTTATGAAAATTTGAGATTAGCAACAGAACTTCCAGACCCTGAACTGAGAAGGACTTTATGGTCTCTTGTGGCTTTCCCAAAATTAAAAAGGCAATTGTTGTGCTATGATCCATTGATTCAAAATCCTAAAGACTTTGTCCAGAATACAATATTTTGGGTAAATCAGGAATTTGCGCTTATTAAGAATGGAAAACCACAACGTAGGGGTAAAATAAATTTGATTGGAAGACTTCAGTTGAGTACAGAGAGATCTCAAATAGAAGATAATCATTCCATTGTGCAGCTAAGAATATTGAGGACTCAAGAGGCAATCATAAAAATACTAAAGATGAGGAAACGCATTACAAACACAGCACTTCAGAGCGAGCTGGTAGAGATTCTAAAAAATATGTTTCTACCATCGAAGAAAATGATAAAAGAGCAATTAGAATGGCTTATTGAACATAAATATATGCGTCGCGACGACGAAGATATTAACACGTTTATATACATGGCCTAA

Protein

MLKEKGQITFEDKWPSMRPIVLKLLKQETVTQTEWQDLFGAVHSVCLWDERGPYKLRDSLQQDITMYIKQAQVRVLAQREDQALLKAYIADSQKKNNNNNIEDSLVRKLMLDSWNQSIFVDIKERLQDSAMKLVQAERNGESFDSQLVIGVRESYVNLCSNTIDKLQIYRENFEAAYMQATEEFYKLKASEHLLANGVQSYMKYADQRLKEEEARAHRYLEPGSGSVAALTQCCERVLIGEHLPTLLAESATLIKAGETEKLQLMFRLLDRVPEGVVPILRDLEAHIVSAGLADMVASADIITTDSEKYVERLLDLFRKFSMLVKDAFLDDPRFLTARDKAYKCVVNDTTVFKLELPSSTLARGSKGTAPESKCPELLANYCDMLLRKTPLSKRLTSEQIEIRLRDVLLVLKYIENKDVFMRYHKVHLTRRLILDSSADSEKEEDMVEWLREVGMPADYVNKLARMFQDVKVSEDLNTQFRADTTRHDAINIKILNAGAWARGSERVTVSLPLELEDYIPEVEEFYKKKHSGRKLQWYHHMSNGTITFANSVGRFDLDVTTFQMAVLFAWNQRPMEKISYENLRLATELPDPELRRTLWSLVAFPKLKRQLLCYDPLIQNPKDFVQNTIFWVNQEFALIKNGKPQRRGKINLIGRLQLSTERSQIEDNHSIVQLRILRTQEAIIKILKMRKRITNTALQSELVEILKNMFLPSKKMIKEQLEWLIEHKYMRRDDEDINTFIYMA

Similarity

Belongs to the cullin family.

Uniprot

H9JPQ6   A0A2A4J8T7   A0A2H1VHL8   A0A3S2NDQ5   A0A212FJP3   A0A0L7L6T4   + More
A0A194RR53   A0A1B0D6C7   A0A1B0GJX2   A0A1Y1LKZ9   A0A336MIF7   A0A1L8DX62   A0A1Q3G1Y8   Q172K9   A0A182H143   A0A1Q3G278   A0A182H0R4   D6WA57   A0A1W4X5U7   A0A1J1ID04   A0A1B6GWT9   A0A067RQL3   A0A224X7X5   A0A023F5R5   A0A146KX50   A0A0A9YZV8   A0A2J7PBI7   A0A1B6CY52   A0A146KRJ7   A0A0A9WIF2   A0A088AUS4   A0A087UQN4   A0A154PIQ3   E0VD80   E2C437   A0A0C9RQ35   A0A1B6L9H9   A0A182UXC1   A0A2A3E675   A0A182LFC8   A0A182Q3U3   A0A1Y9GK92   A0A182XI81   A0A182P706   A0A084VSD1   A0A182IVP0   Q7PR00   A0A182NA68   A0A3R7PGY3   A0A182VX69   A0A182YKG7   A0A182K693   A0A182MB48   A0A232EJN1   A0A1S3DLX9   A0A0M8ZUH0   A0A182R3M1   A0A151IBJ9   A0A151WNL0   A0A158N906   F4WHK1   A0A3L8DSF6   T1IY43   J9K1Q5   A0A2H8TWU2   A0A182FKX1   A0A151J384   A0A2M4AIG0   A0A2R5LJG0   V5I354   W5JH47   A0A2S2PYS7   A0A131YJY0   A0A0L7QL33   A0A0P5P2L0   A0A0P6BJU8   A0A1S3IZ68   A0A151P7B7   E9H0V9   A0A026VV98   W5MIC5   Q0D2D8   A0A1W4Y3Q9   A0A1S3RND2   U3FZM2   A0A218VAI8   A0A226NX48   A0A3Q2YTN3   A0A151K0Z8   K7FS97   H9GB36   A0A2R8QBE5   A0A2K6BW71   G1T087   G3SHP7   A0A2I3HAT7   I3LFR2   A0A0D9S2E9   A0A2Y9DWC6   A0A2K5CZ44  

Pubmed

19121390    22118469    26227816    26354079    28004739    17510324    + More
26483478    18362917    19820115    24845553    25474469    26823975    25401762    20566863    20798317    20966253    24438588    12364791    25244985    28648823    21347285    21719571    30249741    25765539    20920257    23761445    26830274    22293439    21292972    24508170    20431018    23915248    24621616    17381049    21881562    23594743    21993624    22398555    30723633   

EMBL

BABH01015152    NWSH01002449    PCG68279.1    ODYU01002594    SOQ40306.1    RSAL01000184    + More
RVE44836.1    AGBW02008253    OWR53929.1    JTDY01002630    KOB71059.1    KQ459833    KPJ19790.1    AJVK01012034    AJVK01012035    AJWK01022430    GEZM01055619    GEZM01055618    JAV73000.1    UFQS01000617    UFQT01000617    SSX05448.1    SSX25808.1    GFDF01003078    JAV11006.1    GFDL01001197    JAV33848.1    CH477435    EAT40955.1    JXUM01102436    KQ564727    KXJ71822.1    GFDL01001196    JAV33849.1    JXUM01101739    KQ564671    KXJ71929.1    KQ971312    EEZ98589.1    CVRI01000047    CRK98120.1    GECZ01002914    JAS66855.1    KK852482    KDR22920.1    GFTR01007970    JAW08456.1    GBBI01002199    JAC16513.1    GDHC01017578    JAQ01051.1    GBHO01006463    JAG37141.1    NEVH01027088    PNF13705.1    GEDC01018896    GEDC01001914    JAS18402.1    JAS35384.1    GDHC01019518    JAP99110.1    GBHO01038999    JAG04605.1    KK121072    KFM79673.1    KQ434926    KZC11702.1    DS235072    EEB11336.1    GL452364    EFN77423.1    GBYB01009286    JAG79053.1    GEBQ01019641    JAT20336.1    KZ288356    PBC27210.1    AXCN02000217    APCN01000420    ATLV01015920    KE525044    KFB40875.1    AAAB01008859    EAA08065.6    QCYY01002983    ROT66175.1    AXCM01000752    NNAY01003995    OXU18518.1    KQ435883    KOX69759.1    KQ978095    KYM97022.1    KQ982907    KYQ49454.1    ADTU01009012    GL888161    EGI66355.1    QOIP01000004    RLU23360.1    JH431669    ABLF02039783    GFXV01005833    MBW17638.1    KQ980290    KYN16916.1    GGFK01007249    MBW40570.1    GGLE01005515    MBY09641.1    GANP01002245    JAB82223.1    ADMH02001206    ETN63687.1    GGMS01001350    MBY70553.1    GEDV01010191    JAP78366.1    KQ414934    KOC59305.1    GDIQ01140967    JAL10759.1    GDIP01013818    JAM89897.1    AKHW03000640    KYO44928.1    GL732582    EFX74526.1    KK108326    EZA46754.1    AHAT01003064    AHAT01003065    AAMC01039068    AAMC01039069    AAMC01039070    BC121941    AAI21942.1    GAEP01000391    JAB54430.1    MUZQ01000019    OWK62949.1    AWGT02000295    OXB72346.1    KQ981229    KYN44340.1    AGCU01089226    AGCU01089227    AAWZ02031579    AAWZ02031580    AAWZ02031581    BX324225    AAGW02009201    AAGW02009202    AAGW02009203    CABD030081437    CABD030081438    CABD030081439    CABD030081440    CABD030081441    CABD030081442    ADFV01056334    ADFV01056335    ADFV01056336    ADFV01056337    ADFV01056338    ADFV01056339    AEMK02000070    DQIR01100713    HDA56189.1    AQIB01092915    AQIB01092916    AQIB01092917    AQIB01092918    AQIB01092919    AQIB01092920    AQIB01092921    AQIB01092922    AQIB01092923    AQIB01092924   

Proteomes

UP000005204    UP000218220    UP000283053    UP000007151    UP000037510    UP000053240    + More
UP000092462    UP000092461    UP000008820    UP000069940    UP000249989    UP000007266    UP000192223    UP000183832    UP000027135    UP000235965    UP000005203    UP000054359    UP000076502    UP000009046    UP000008237    UP000075903    UP000242457    UP000075882    UP000075886    UP000075840    UP000076407    UP000075885    UP000030765    UP000075880    UP000007062    UP000075884    UP000283509    UP000075920    UP000076408    UP000075881    UP000075883    UP000215335    UP000079169    UP000053105    UP000075900    UP000078542    UP000075809    UP000005205    UP000007755    UP000279307    UP000007819    UP000069272    UP000078492    UP000000673    UP000053825    UP000085678    UP000050525    UP000000305    UP000053097    UP000018468    UP000008143    UP000192224    UP000087266    UP000197619    UP000198419    UP000264820    UP000078541    UP000007267    UP000001646    UP000000437    UP000233120    UP000001811    UP000001519    UP000001073    UP000008227    UP000029965    UP000248480    UP000233020   

PRIDE

H9JPQ6    I3LFR2   

Pfam

PF10557   Cullin_Nedd8        + More
PF00888   Cullin
PF00293   NUDIX
PF07258   COMM_domain
PF03690   UPF0160

Interpro

IPR016159   Cullin_repeat-like_dom_sf        + More
IPR016158   Cullin_homology       
IPR036317   Cullin_homology_sf       
IPR019559   Cullin_neddylation_domain       
IPR016157   Cullin_CS       
IPR001373   Cullin_N       
IPR036388   WH-like_DNA-bd_sf       
IPR036390   WH_DNA-bd_sf       
IPR004827   bZIP       
IPR020476   Nudix_hydrolase       
IPR015797   NUDIX_hydrolase-like_dom_sf       
IPR000086   NUDIX_hydrolase_dom       
IPR003226   Met-dep_prot_hydro       
IPR037354   Commd2       
IPR017920   COMM       

SUPFAM

SSF74788   SSF74788        + More
SSF46785   SSF46785       
SSF75632   SSF75632       
SSF55811   SSF55811       

Gene 3D

1.10.10.10    

CDD

cd04750  Commd2

ProteinModelPortal

H9JPQ6   A0A2A4J8T7   A0A2H1VHL8   A0A3S2NDQ5   A0A212FJP3   A0A0L7L6T4   + More
A0A194RR53   A0A1B0D6C7   A0A1B0GJX2   A0A1Y1LKZ9   A0A336MIF7   A0A1L8DX62   A0A1Q3G1Y8   Q172K9   A0A182H143   A0A1Q3G278   A0A182H0R4   D6WA57   A0A1W4X5U7   A0A1J1ID04   A0A1B6GWT9   A0A067RQL3   A0A224X7X5   A0A023F5R5   A0A146KX50   A0A0A9YZV8   A0A2J7PBI7   A0A1B6CY52   A0A146KRJ7   A0A0A9WIF2   A0A088AUS4   A0A087UQN4   A0A154PIQ3   E0VD80   E2C437   A0A0C9RQ35   A0A1B6L9H9   A0A182UXC1   A0A2A3E675   A0A182LFC8   A0A182Q3U3   A0A1Y9GK92   A0A182XI81   A0A182P706   A0A084VSD1   A0A182IVP0   Q7PR00   A0A182NA68   A0A3R7PGY3   A0A182VX69   A0A182YKG7   A0A182K693   A0A182MB48   A0A232EJN1   A0A1S3DLX9   A0A0M8ZUH0   A0A182R3M1   A0A151IBJ9   A0A151WNL0   A0A158N906   F4WHK1   A0A3L8DSF6   T1IY43   J9K1Q5   A0A2H8TWU2   A0A182FKX1   A0A151J384   A0A2M4AIG0   A0A2R5LJG0   V5I354   W5JH47   A0A2S2PYS7   A0A131YJY0   A0A0L7QL33   A0A0P5P2L0   A0A0P6BJU8   A0A1S3IZ68   A0A151P7B7   E9H0V9   A0A026VV98   W5MIC5   Q0D2D8   A0A1W4Y3Q9   A0A1S3RND2   U3FZM2   A0A218VAI8   A0A226NX48   A0A3Q2YTN3   A0A151K0Z8   K7FS97   H9GB36   A0A2R8QBE5   A0A2K6BW71   G1T087   G3SHP7   A0A2I3HAT7   I3LFR2   A0A0D9S2E9   A0A2Y9DWC6   A0A2K5CZ44  

PDB

3DQV     E-value=6.17599e-158,     Score=1433

KEGG

101741088    K10612 cullin 5 | (RefSeq) cullin-5

PATHWAY

04120    Ubiquitin mediated proteolysis - Bombyx mori (domestic silkworm)

GO

GO:0006511   GO:0031461   GO:0031625   GO:0003700   GO:0019005   GO:0031466   GO:0031146   GO:0043161   GO:0016787   GO:0005515   GO:0000287   GO:0016620   GO:0003676   GO:0016491   GO:0015930  

Length:

744

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.00256

Exp number, first 60 AAs:

0

Total prob of N-in:

0.00012

outside

1  -  744

 

 

Pi

240.930313

Theta

187.759314

Tajima's D

0.644826

CLR

0.203353

CSRT

0.550772461376931

Interpretation

Uncertain