Gene

KWMTBOMO13712  Validated by peptides from experiments

Pre Gene Modal

BGIBMGA011009

Annotation

PREDICTED:_LOW_QUALITY_PROTEIN:_E3_UFM1-protein_ligase_1_homolog_[Bombyx_mori]

Location

Bomo_Chr23(-):7434076-7442114      View in EpiBrowser

Full name

E3 UFM1-protein ligase 1 homolog      

Alternative Name

E3 UFM1-protein transferase 1 homolog
UFM1 specific ligase 1

Location in the cell

Cytoplasmic   Reliability : 1.993 Nuclear   Reliability : 2.256

CDS

ATGGCTCCAGCTACTGATTGGGACGAAATTAAAAGGCTAGCAGCTGATTTTCAAAAAGCTCAATTGAGTACTACAGCTCAAAGATTATCAGAACGAAACTGTATTGAGATCGTCACAAAATTAATTGAACTTAAATTAATAGATGTTATTTTTACAAATGATGGCAAAGAATATCTCACTTCGCTCCAACTTATAAAGGAAATGAAAGATGAGTTGTATGTGCATGGAGGCCGAATAAACACTGTTGATTTAGCCAAAGAGTTAAATGTGGATTTTAACCACATTACAACGCACATTCCGGAAATTGTAAAAGGCAAAGATGTTCAGTTGATATCTGGTTATTTGATTACAAATTATTATTTGGAAAAAATTGCCAGAGAAGTAAACGAAAAGTTACAGCTTCAAGGCTACATATCTGTTGGGGAATTAACCTTGCATTATGATTTACCAGCAGATTTGATCCAGCATAGTGTTCTTGAAAAGTTTTTGGGTAAAATCATCATTGGAAAGCAAGATCCATCTGAGCCCAGAACCTTTTACACTGATGAATACATAACCAGGACAAAAGCTAAGATAAGGGGTGCATTAATGGGACTCTTAAAACCAACTCCAATTGCTGTTATAGTAAATCATTGCAATTTATCTGACCGTTTGTTCTTGTCACTTTTTGATCAATTAAATGCTCCTGGTGTATTAACAGGCAAGCAAGCTGGAGCTATTTATGTGCCATCTAGTTACACAAAGTCACAAAATGATTGGGTAATAAATTTCTACAAACAGAACAACTACCTTGAATATGATGCTCTCTCAAGATTAGGAGTTTCAGATCCAAAAGGATATGTTAAAAGGATTATTTTAAATGAAGAGCTCACATTTCTTAGCAGCTGTGTAATTGGATCACAGATTAAAGAGCAATTGGAAACCGCACTAGAAGAATGCATAGCATCTAAAAGTTATTTAGATGTTGTCACTTTGTTGCCATCAATTTTTTCAGATAGTGATATTGAAAGCATTTTAGATGAGTTATTGAGAAACAATGTTAAATCAACAGTTCTCTTTGAAAACACTGTATTCAGCTGTCATTATATTGAAGATTTGAAACAGACTTGCATGCCAATAACGCAAAAAAATGCAGAGGCTTTGGTTAAATCTGGTAGATATCAACAGTTTTATCTTGAGAAGCAGCTTTCTAAAAACTTTGATATGGTACAATCAGGTCCTGCTGATCACAAAGCAGAGAGAAGGGAAGAACGCAGAAGAAAGGCTGCTTCAGGTAAAGGTGGCGGTGGAACTCAGGGTAGAGAAACTAAAACCAAGACTGTTAAAAAGCACAACAGGTCAAAACAGGTAGTCCAGGATTCAGATTCTGATGATGGACATGCAGTTTCAAGAAAACCAGCACATTTAGAAGTAGTTTCAGTGGAAGATATAGAAAAAGTAATTAAAGAACCATTGGAAAATGAAGGTCTAGATGACCTAGTTACTAGGATTGCAGAACATCTACAAGGAAGCCTCAATCAAATTGGTCTGGCTATTGCCAAAGAAACGGCCGAAAAATTGCTTCAAGATTCAACACAAAACAGGAAACAAACTCATTCATCAGCTCAGGACAAAATTAATATCTTAGTGAACGATATAAAACTATATGAAAAAGGAATAAAGACCTTTGCAGCTGAGCAACAAGCACCCTTTATTAAATATTTATTAAAATCTTTAGGAGGTGACATACTATCTGAGTTTTGCAAATATGCTGCGAGTCAGTGTAATCTTTCTATGCAAAACGAAACTCTCTCAATTGAACAGAGGAACAAAATAATAAATGACGTTACTGAGGAATTCAAGAAACCATTAACAATATTAAGTGCGTCTATAAATGAACAAAGCATGGAATCATTTTTTCAAGCTATTGATGTTGCTTTATCTGACTTTGGGATGATATTGAAAAAGGTGGATAAGAAGAAAGACAAGATGCTAGTGCAAAATCATAGAGAGAAATTAATTTCGGAGTTGGAAAACTGTGATGACCCAGCACTGTGCCTGCACATGGCTGTGTTATCGATATTCACAATTGTCACTCAAACCATGTTACATGCATCTGGCAGACAAGTTGCTGTTATTATTAATTATTTGAAAAACCACATAAGAGAGGAAGATTTTGAAAAATTACACTCATATCATGAATTAGTTACCAAGTTTTTGACTTCAAATGGAGATGACAGAACGGAAATTGAAGATAAGTTAAGAAGTGAATTGACAACTTTAAAAAATGTTGTTCACGACATCAAGAAGTACAAATAA

Protein

MAPATDWDEIKRLAADFQKAQLSTTAQRLSERNCIEIVTKLIELKLIDVIFTNDGKEYLTSLQLIKEMKDELYVHGGRINTVDLAKELNVDFNHITTHIPEIVKGKDVQLISGYLITNYYLEKIAREVNEKLQLQGYISVGELTLHYDLPADLIQHSVLEKFLGKIIIGKQDPSEPRTFYTDEYITRTKAKIRGALMGLLKPTPIAVIVNHCNLSDRLFLSLFDQLNAPGVLTGKQAGAIYVPSSYTKSQNDWVINFYKQNNYLEYDALSRLGVSDPKGYVKRIILNEELTFLSSCVIGSQIKEQLETALEECIASKSYLDVVTLLPSIFSDSDIESILDELLRNNVKSTVLFENTVFSCHYIEDLKQTCMPITQKNAEALVKSGRYQQFYLEKQLSKNFDMVQSGPADHKAERREERRRKAASGKGGGGTQGRETKTKTVKKHNRSKQVVQDSDSDDGHAVSRKPAHLEVVSVEDIEKVIKEPLENEGLDDLVTRIAEHLQGSLNQIGLAIAKETAEKLLQDSTQNRKQTHSSAQDKINILVNDIKLYEKGIKTFAAEQQAPFIKYLLKSLGGDILSEFCKYAASQCNLSMQNETLSIEQRNKIINDVTEEFKKPLTILSASINEQSMESFFQAIDVALSDFGMILKKVDKKKDKMLVQNHREKLISELENCDDPALCLHMAVLSIFTIVTQTMLHASGRQVAVIINYLKNHIREEDFEKLHSYHELVTKFLTSNGDDRTEIEDKLRSELTTLKNVVHDIKKYK

Description

E3 UFM1-protein ligase that mediates ufmylation of target proteins.

Subunit

Interacts with Ufc1.

Similarity

Belongs to the UFL1 family.

Keywords

Complete proteome   Reference proteome   Transferase   Ubl conjugation pathway   Alternative splicing  

Feature

chain  E3 UFM1-protein ligase 1 homolog
splice variant  In isoform B.

Uniprot

A0A2A4J353   A0A1E1WEN3   A0A2H1VZ84   H9JNA6   A0A3S2NUF9   A0A194PL37   + More
A0A194QP79   A0A212FJK4   A0A0L7LML8   A0A2K7P693   Q0IG18   A0A182H921   A0A023EW51   A0A1L8DB94   A0A1L8DAU7   B0WU24   A0A1B0C9L2   A0A1Q3F735   A0A0A1XHR6   A0A0A1X755   A0A1W4WYX7   A0A182IMR2   A0A182QHX1   U5EZ64   A0A034WCI6   A0A0K8WBJ6   A0A182NTH3   A0A1J1IFV6   A0A336LPR7   A0A182F668   W8B914   A0A2M4BEN7   A0A2M4BEE1   A0A182TUR5   A0A2M4A6A8   A0A2M4A6E3   A0A0M4EMZ7   A0A2M3Z3A3   A0A182XZS5   A0A084WHE4   A0A2P8ZCH7   A0A182L2Q7   A0A182VEP3   A0A182X1D8   W5JR38   A0A182RJD1   A0A182W7K3   Q7Q373   A0A182IEB8   A0A0K8TMS3   A0A2J7RMS1   B4I4N0   B4QYZ3   A0A182LV14   A0A0B4K6K7   Q9VI55   A0A182PCX5   B3P2S2   A0A182JQL8   A0A1W4USC0   B4JV25   N6UEX2   A0A1B6D5T8   B4KDK5   B3LYC0   B4PS24   A0A067RHQ6   U4U460   A0A0J7KUS1   A0A026WAF0   F4WSX5   B4GEL3   A0A195F7F9   A0A232ERP4   Q296V2   K7ITI0   A0A3B0KK81   A0A0L0BYJ0   A0A195AYW7   B4LZW7   E2ALF3   A0A0L7RFK4   A0A1I8PFY6   B4NAB3   A0A069DX29   A0A0N7Z9K7   A0A1B0BM19   A0A1A9W1K1   A0A1A9YAW7   R4G486   A0A1A9VGU3   A0A310SQJ9   A0A146M262   A0A0A9WC89   A0A0K8SRL7   A0A210QUX3   Q9VI55-2   A0A0C9PQD5  

EC Number

2.3.2.-

Pubmed

19121390    26354079    22118469    26227816    17510324    26483478    + More
24945155    25830018    25348373    24495485    25244985    24438588    29403074    20966253    20920257    23761445    12364791    26369729    17994087    10731132    12537568    12537572    12537573    12537574    16110336    17569856    17569867    12537569    26872069    23537049    24845553    24508170    30249741    21719571    28648823    15632085    20075255    26108605    20798317    26334808    27129103    26823975    25401762    28812685   

EMBL

NWSH01003372    PCG66431.1    GDQN01005606    JAT85448.1    ODYU01005373    SOQ46145.1    + More
BABH01019626    BABH01019627    RSAL01000184    RVE44852.1    KQ459600    KPI94151.1    KQ461195    KPJ06780.1    AGBW02008253    OWR53916.1    JTDY01000577    KOB76604.1    CH477274    JXUM01030313    JXUM01030314    KQ560880    KXJ80505.1    GAPW01000252    JAC13346.1    GFDF01010490    JAV03594.1    GFDF01010491    JAV03593.1    DS232099    AJWK01002457    AJWK01002458    AJWK01002459    AJWK01002460    AJWK01002461    GFDL01011670    JAV23375.1    GBXI01003790    JAD10502.1    GBXI01007722    JAD06570.1    AXCN02000703    GANO01001358    JAB58513.1    GAKP01005686    JAC53266.1    GDHF01003783    JAI48531.1    CVRI01000047    CRK97918.1    UFQS01000045    UFQT01000045    SSW98435.1    SSX18821.1    GAMC01013006    GAMC01013003    GAMC01013002    GAMC01013000    GAMC01012995    GAMC01012992    JAB93563.1    GGFJ01002280    MBW51421.1    GGFJ01002279    MBW51420.1    GGFK01002949    MBW36270.1    GGFK01002971    MBW36292.1    CP012526    ALC46915.1    GGFM01002222    MBW22973.1    ATLV01023808    KE525346    KFB49638.1    PYGN01000105    PSN54204.1    ADMH02000676    ETN65365.1    AAAB01008964    APCN01005200    GDAI01001951    JAI15652.1    NEVH01002552    PNF42125.1    CH480821    CM000364    AXCM01001390    AE014297    AFH06276.1    AY051887    CH954181    CH916374    APGK01037946    KB740949    ENN77202.1    GEDC01016258    JAS21040.1    CH933806    CH902617    CM000160    KK852463    KDR23401.1    KB631923    ERL87133.1    LBMM01003030    KMQ94051.1    KK107295    QOIP01000003    EZA53035.1    RLU24365.1    GL888331    EGI62679.1    CH479182    KQ981768    KYN36004.1    NNAY01002582    OXU20997.1    CM000070    AAZX01003331    OUUW01000008    SPP84178.1    JRES01001243    KNC24334.1    KQ976701    KYM77230.1    CH940650    GL440604    EFN65758.1    KQ414605    KOC69630.1    CH964232    GBGD01000533    JAC88356.1    GDKW01000275    JAI56320.1    JXJN01016644    GAHY01000991    JAA76519.1    KQ760123    OAD61859.1    GDHC01004751    JAQ13878.1    GBHO01038180    GBHO01038179    JAG05424.1    JAG05425.1    GBRD01009827    JAG55997.1    NEDP02001786    OWF52506.1    GBYB01003423    JAG73190.1   

Proteomes

UP000218220    UP000005204    UP000283053    UP000053268    UP000053240    UP000007151    + More
UP000037510    UP000008820    UP000069940    UP000249989    UP000002320    UP000092461    UP000192223    UP000075880    UP000075886    UP000075884    UP000183832    UP000069272    UP000075902    UP000092553    UP000076408    UP000030765    UP000245037    UP000075882    UP000075903    UP000076407    UP000000673    UP000075900    UP000075920    UP000007062    UP000075840    UP000235965    UP000001292    UP000000304    UP000075883    UP000000803    UP000075885    UP000008711    UP000075881    UP000192221    UP000001070    UP000019118    UP000009192    UP000007801    UP000002282    UP000027135    UP000030742    UP000036403    UP000053097    UP000279307    UP000007755    UP000008744    UP000078541    UP000215335    UP000001819    UP000002358    UP000268350    UP000037069    UP000078540    UP000008792    UP000000311    UP000053825    UP000095300    UP000007798    UP000092460    UP000091820    UP000092443    UP000078200    UP000242188   

PRIDE

H9JNA6    B0WU24    Q7Q373    B4I4N0    B4QYZ3    Q9VI55    + More
B3P2S2    B3LYC0    B4PS24    B4GEL3    Q296V2    B4NAB3   

Pfam

PF09743   E3_UFM1_ligase        + More
PF00631   G-gamma
PF07690   MFS_1
PF05405   Mt_ATP-synt_B

Interpro

IPR018611   E3_UFM1_ligase_1        + More
IPR036284   GGL_sf       
IPR015898   G-protein_gamma-like_dom       
IPR020846   MFS_dom       
IPR011701   MFS       
IPR036259   MFS_trans_sf       
IPR008688   ATP_synth_Bsub_B/MI25       

SUPFAM

SSF48670   SSF48670        + More
SSF103473   SSF103473       

Gene 3D

4.10.260.10    

CDD

cd00068  GGL
cd06174  MFS

ProteinModelPortal

A0A2A4J353   A0A1E1WEN3   A0A2H1VZ84   H9JNA6   A0A3S2NUF9   A0A194PL37   + More
A0A194QP79   A0A212FJK4   A0A0L7LML8   A0A2K7P693   Q0IG18   A0A182H921   A0A023EW51   A0A1L8DB94   A0A1L8DAU7   B0WU24   A0A1B0C9L2   A0A1Q3F735   A0A0A1XHR6   A0A0A1X755   A0A1W4WYX7   A0A182IMR2   A0A182QHX1   U5EZ64   A0A034WCI6   A0A0K8WBJ6   A0A182NTH3   A0A1J1IFV6   A0A336LPR7   A0A182F668   W8B914   A0A2M4BEN7   A0A2M4BEE1   A0A182TUR5   A0A2M4A6A8   A0A2M4A6E3   A0A0M4EMZ7   A0A2M3Z3A3   A0A182XZS5   A0A084WHE4   A0A2P8ZCH7   A0A182L2Q7   A0A182VEP3   A0A182X1D8   W5JR38   A0A182RJD1   A0A182W7K3   Q7Q373   A0A182IEB8   A0A0K8TMS3   A0A2J7RMS1   B4I4N0   B4QYZ3   A0A182LV14   A0A0B4K6K7   Q9VI55   A0A182PCX5   B3P2S2   A0A182JQL8   A0A1W4USC0   B4JV25   N6UEX2   A0A1B6D5T8   B4KDK5   B3LYC0   B4PS24   A0A067RHQ6   U4U460   A0A0J7KUS1   A0A026WAF0   F4WSX5   B4GEL3   A0A195F7F9   A0A232ERP4   Q296V2   K7ITI0   A0A3B0KK81   A0A0L0BYJ0   A0A195AYW7   B4LZW7   E2ALF3   A0A0L7RFK4   A0A1I8PFY6   B4NAB3   A0A069DX29   A0A0N7Z9K7   A0A1B0BM19   A0A1A9W1K1   A0A1A9YAW7   R4G486   A0A1A9VGU3   A0A310SQJ9   A0A146M262   A0A0A9WC89   A0A0K8SRL7   A0A210QUX3   Q9VI55-2   A0A0C9PQD5  

KEGG

101745790    K22755 E3 UFM1-protein ligase 1 [EC:2.3.2.-] | (RefSeq) E3 UFM1-protein ligase 1 homolog

GO

GO:0007186   GO:0016874   GO:0055085   GO:0016021   GO:0016740   GO:0000276   GO:0015078   GO:0015986   GO:0034976   GO:0071568   GO:0032434   GO:0005789   GO:1990592   GO:0012505  

Length:

765

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.34031

Exp number, first 60 AAs:

0.00019

Total prob of N-in:

0.00204

outside

1  -  765

 

 

Pi

26.216834

Theta

197.443365

Tajima's D

-1.716118

CLR

0.968931

CSRT

0.0374481275936203

Interpretation

Possibly Positive selection