Gene

KWMTBOMO13707  Validated by peptides from experiments

Pre Gene Modal

BGIBMGA011095

Annotation

Sarah_[Operophtera_brumata]

Location

Bomo_Chr23(+):7359945-7360782      View in EpiBrowser

Full name

Protein sarah      

Alternative Name

Protein nebula

Location in the cell

Nuclear   Reliability : 2.433

CDS

ATGGCACACCAAGAAGACTACGATCTATTTCCCGAAGAAAACGTTTACATAAATCCAGAAGATGGAATGCCTAATATTCATCCTAATATAGTTAATTTTGAACAAGAAAGTGATACTCAAGATGAAGTCGACAACTTTGATGACCTACCTAAATCTGTTATTGTAACAAACATTAATAGCATCGTTTTTTCTGATGAAAAATTGAAAAAAGAGATGGAAGACTTATTCCGTACATTTTCGGAAAATGTAACGTTTCAGTGGCTCCGCAGTTTCAAAAGATTACGCGTTAATTATGACAACCCCTTAGCTGCCGCAAATGCACGAATTCAATTACATCAATACCAATTTTATGATTCATGCATAAATTGCTATTTTGCCCAACCTGTGACACCAATTTCATTTAAGAATCTCAGACCCCCGGCGCCTGTTAAGCAATTTTTGATTTCACCTCCATCAAGTCCTCCAGTTGGCTGGGAGCCTCGAGAAGAAGGTGAACCCATTGTGAATCATGACCTTTTAGCGGCACTTGCAAGTTTATCTCCTGGTGAAAGTCGAGAGCTACACGCACCCACACCAACACAACCAGCCATTGTAGTGCACACTGCAATATCAGAGGTTTCTCCTCCGCCTGGTGCAAAAAAAATTCCTCACACTCGTTGTCCAGAATACTGA

Protein

MAHQEDYDLFPEENVYINPEDGMPNIHPNIVNFEQESDTQDEVDNFDDLPKSVIVTNINSIVFSDEKLKKEMEDLFRTFSENVTFQWLRSFKRLRVNYDNPLAAANARIQLHQYQFYDSCINCYFAQPVTPISFKNLRPPAPVKQFLISPPSSPPVGWEPREEGEPIVNHDLLAALASLSPGESRELHAPTPTQPAIVVHTAISEVSPPPGAKKIPHTRCPEY

Description

Required for elongation of meiosis I spindle. Critical for ovulation, meiotic progression in oocytes and female courtship behavior, including their postmating changes. Regulates female meiosis by controlling calcineurin activity in the germline. Has a role in calcium signaling during egg activation; bcd mRNA polyadenylation and translation in the oocyte.

Subunit

Interacts with Pp2B-14D, CanA-14F and CanB2.

Similarity

Belongs to the RCAN family.

Keywords

Behavior   Calcium   Cell cycle   Complete proteome   Developmental protein   Differentiation   Meiosis   Oogenesis   Phosphoprotein   Reference proteome  

Feature

chain  Protein sarah

Uniprot

H9JNJ1   A0A3S2N974   A0A2H1VCF1   A0A2A4J3X4   A0A0L7LRD8   A0A194QN50   + More
A0A194PN32   A0A212FJK8   S4P8Q7   A0A1B0C9K8   A0A1L8DJ75   A0A0M4EGQ4   A0A1I8N1F1   A0A1B0D351   A0A1A9WHP8   B4KA03   A0A1A9ZM61   D3TS45   A0A1A9XU93   A0A1B0BND5   A0A1A9VAZ4   A0A1I8PKR5   A0A0K8TRZ5   Q16EQ0   A0A1W4VG09   A0A1W4X9J2   B4QX66   B4HLC6   A0A0B4LHI3   Q9XZL8   B4PR28   A0A1B0GCT4   A0A0T6B3E3   A0A182Q8L1   A0A0P6J6E0   A0A182Y1E5   A0A1J1IHJ4   A0A0K8TVM4   A0A034VTG7   A0A182SRT6   A0A0A1XIY7   A0A182R2F1   B3MTV0   B3P0Z3   A0A084WSW4   A0A1W4X8A2   A0A1W7R6U7   A0A182UH50   A0A182PHS4   A0A182KNB2   Q5TQS6   A0A182I4R2   A0A182X4R3   A0A182N7R9   A0A182V3F5   A0A182MLD3   B4JG19   A0A182JZ67   V5IAC1   A0A1B6FWS4   B4GMJ8   B4LXZ9   Q294V8   W8C2K5   D6WAW5   B4NL00   A0A3B0JRL6   A0A1B6I9H3   A0A1B6LR81   A0A1B6KZ48   A0A1Y1M3Y4   A0A2M3ZC41   A0A0L0BNR4   A0A2M3ZIT4   A0A182FFR6   K7J5X4   A0A1Q3G1M7   A0A1Q3G1Z4   A0A232EJH7   A0A1B6DA33   A0A1B6EC88   A0A154PIS6   A0A1Q3G1W2   A0A2M4BWA7   A0A1Q3G1W5   W5JC49   A0A2M4AWZ6   E2C436   A0A151WP33   A0A158N908   J3JYQ2   A0A3L8DTY2   A0A0K8S3Z4   U4UM81   A0A151J381   A0A151K154   A0A0A9WH42   A0A026VSK6   F4WHK0   E2ALB7  

Pubmed

19121390    26227816    26354079    22118469    23622113    25315136    + More
17994087    18057021    20353571    26369729    17510324    10731132    12537568    12537572    12537573    12537574    16110336    17569856    17569867    12537569    15611177    16860743    16860744    22421435    17550304    26999592    25244985    25348373    25830018    24438588    20966253    12364791    14747013    17210077    15632085    24495485    18362917    19820115    28004739    26108605    20075255    28648823    20920257    23761445    20798317    21347285    22516182    30249741    23537049    25401762    26823975    24508170    21719571   

EMBL

BABH01019613    RSAL01000184    RVE44859.1    ODYU01001804    SOQ38507.1    NWSH01003372    + More
PCG66436.1    JTDY01000250    KOB78063.1    KQ461195    KPJ06784.1    KQ459600    KPI94144.1    AGBW02008253    OWR53914.1    GAIX01007187    JAA85373.1    AJWK01002451    AJWK01002452    GFDF01007578    JAV06506.1    CP012526    ALC45358.1    AJVK01023278    AJVK01023279    CH933806    EDW15651.1    KRG01654.1    EZ424247    ADD20523.1    JXJN01017337    GDAI01000672    JAI16931.1    CH478619    EAT32710.1    CM000364    EDX12720.1    CH480815    EDW41946.1    AE014297    AHN57360.1    AF147700    AY061194    CM000160    EDW97350.1    CCAG010002227    LJIG01016177    KRT81383.1    AXCN02000584    GDUN01000116    JAN95803.1    CVRI01000047    CRK97921.1    GDHF01033986    JAI18328.1    GAKP01013233    GAKP01013232    JAC45719.1    GBXI01002998    JAD11294.1    CH902623    EDV30231.1    CH954181    EDV49112.1    ATLV01026739    KE525418    KFB53308.1    GEHC01000763    JAV46882.1    AAAB01008960    EAL40138.3    APCN01002346    AXCM01001108    CH916369    EDV92558.1    GALX01001445    JAB67021.1    GECZ01015170    JAS54599.1    CH479185    EDW38072.1    CH940650    EDW66865.1    CM000070    EAL28855.2    GAMC01010591    JAB95964.1    KQ971312    EEZ99190.2    CH964272    EDW84203.1    OUUW01000008    SPP83653.1    GECU01024149    JAS83557.1    GEBQ01013784    JAT26193.1    GEBQ01023260    JAT16717.1    GEZM01041321    GEZM01041320    JAV80519.1    GGFM01005328    MBW26079.1    JRES01001582    KNC21730.1    GGFM01007703    MBW28454.1    GFDL01001365    JAV33680.1    GFDL01001223    JAV33822.1    NNAY01003995    OXU18519.1    GEDC01016155    GEDC01014739    GEDC01008450    JAS21143.1    JAS22559.1    JAS28848.1    GEDC01027792    GEDC01001791    JAS09506.1    JAS35507.1    KQ434926    KZC11703.1    GFDL01001262    JAV33783.1    GGFJ01008215    MBW57356.1    GFDL01001255    JAV33790.1    ADMH02001932    ETN60460.1    GGFK01011998    MBW45319.1    GL452364    EFN77422.1    KQ982907    KYQ49455.1    ADTU01009013    BT128382    AEE63340.1    QOIP01000004    RLU23359.1    GBRD01017835    GBRD01017834    JAG47992.1    KB632275    ERL91115.1    KQ980290    KYN16915.1    KQ981229    KYN44339.1    GBHO01039439    GBHO01039438    GDHC01011144    JAG04165.1    JAG04166.1    JAQ07485.1    KK108326    EZA46753.1    GL888161    EGI66354.1    GL440589    EFN65764.1   

Proteomes

UP000005204    UP000283053    UP000218220    UP000037510    UP000053240    UP000053268    + More
UP000007151    UP000092461    UP000092553    UP000095301    UP000092462    UP000091820    UP000009192    UP000092445    UP000092443    UP000092460    UP000078200    UP000095300    UP000008820    UP000192221    UP000192223    UP000000304    UP000001292    UP000000803    UP000002282    UP000092444    UP000075886    UP000076408    UP000183832    UP000075901    UP000075900    UP000007801    UP000008711    UP000030765    UP000075902    UP000075885    UP000075882    UP000007062    UP000075840    UP000076407    UP000075884    UP000075903    UP000075883    UP000001070    UP000075881    UP000008744    UP000008792    UP000001819    UP000007266    UP000007798    UP000268350    UP000037069    UP000069272    UP000002358    UP000215335    UP000076502    UP000000673    UP000008237    UP000075809    UP000005205    UP000279307    UP000030742    UP000078492    UP000078541    UP000053097    UP000007755    UP000000311   

PRIDE

H9JNJ1    Q9XZL8   

Pfam

PF04847   Calcipressin        + More
PF10168   Nup88

Interpro

IPR035979   RBD_domain_sf        + More
IPR012677   Nucleotide-bd_a/b_plait_sf       
IPR006931   Calcipressin       
IPR037700   NUP88/NUP82       
IPR019321   Nucleoporin_Nup88       
IPR000618   Insect_cuticle       

SUPFAM

SSF54928   SSF54928       

Gene 3D

3.30.70.330    

ProteinModelPortal

H9JNJ1   A0A3S2N974   A0A2H1VCF1   A0A2A4J3X4   A0A0L7LRD8   A0A194QN50   + More
A0A194PN32   A0A212FJK8   S4P8Q7   A0A1B0C9K8   A0A1L8DJ75   A0A0M4EGQ4   A0A1I8N1F1   A0A1B0D351   A0A1A9WHP8   B4KA03   A0A1A9ZM61   D3TS45   A0A1A9XU93   A0A1B0BND5   A0A1A9VAZ4   A0A1I8PKR5   A0A0K8TRZ5   Q16EQ0   A0A1W4VG09   A0A1W4X9J2   B4QX66   B4HLC6   A0A0B4LHI3   Q9XZL8   B4PR28   A0A1B0GCT4   A0A0T6B3E3   A0A182Q8L1   A0A0P6J6E0   A0A182Y1E5   A0A1J1IHJ4   A0A0K8TVM4   A0A034VTG7   A0A182SRT6   A0A0A1XIY7   A0A182R2F1   B3MTV0   B3P0Z3   A0A084WSW4   A0A1W4X8A2   A0A1W7R6U7   A0A182UH50   A0A182PHS4   A0A182KNB2   Q5TQS6   A0A182I4R2   A0A182X4R3   A0A182N7R9   A0A182V3F5   A0A182MLD3   B4JG19   A0A182JZ67   V5IAC1   A0A1B6FWS4   B4GMJ8   B4LXZ9   Q294V8   W8C2K5   D6WAW5   B4NL00   A0A3B0JRL6   A0A1B6I9H3   A0A1B6LR81   A0A1B6KZ48   A0A1Y1M3Y4   A0A2M3ZC41   A0A0L0BNR4   A0A2M3ZIT4   A0A182FFR6   K7J5X4   A0A1Q3G1M7   A0A1Q3G1Z4   A0A232EJH7   A0A1B6DA33   A0A1B6EC88   A0A154PIS6   A0A1Q3G1W2   A0A2M4BWA7   A0A1Q3G1W5   W5JC49   A0A2M4AWZ6   E2C436   A0A151WP33   A0A158N908   J3JYQ2   A0A3L8DTY2   A0A0K8S3Z4   U4UM81   A0A151J381   A0A151K154   A0A0A9WH42   A0A026VSK6   F4WHK0   E2ALB7  

PDB

1WEY     E-value=1.17185e-15,     Score=200

KEGG

101740260    no KO assigned | (RefSeq) protein sarah

GO

GO:0003676   GO:0019722   GO:0007143   GO:0007005   GO:0030431   GO:0035039   GO:0070884   GO:0046008   GO:0005634   GO:0005759   GO:0007343   GO:0007616   GO:0008355   GO:0004721   GO:0048477   GO:0051321   GO:0045924   GO:0005737   GO:0007275   GO:0000055   GO:0017056   GO:0005623   GO:0000056   GO:0008597   GO:0042302   GO:0000166   GO:0022857   GO:0005515   GO:0000287   GO:0016620   GO:0016787   GO:0016491   GO:0015930  

PANTHER

PTHR10300   PTHR13257  

Length:

223

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.00052

Exp number, first 60 AAs:

0.00011

Total prob of N-in:

0.04473

outside

1  -  223

 

 

Pi

303.664459

Theta

219.961582

Tajima's D

1.177144

CLR

0.020045

CSRT

0.705314734263287

Interpretation

Uncertain