Silkworm Genome Informatics Database

Gene

KWMTBOMO13674

Pre Gene Modal

BGIBMGA011028

Annotation

PREDICTED:_apaf-1_protein_isoform_X1_[Bombyx_mori]

Location

Bomo_Chr23(-):5409353-5441440 View in EpiBrowser

Location in the cell

Cytoplasmic Reliability : 1.358 Nuclear Reliability : 2.002

CDS

ATGGATCTCAAGAACAGGAAGCTGCTGCAGCACAATCAGCAGGCTATCATCAAAGATCTAGATGTTCAGTACATTCTAGACGAACTTTACACGAAACAAGCTATATCTTCAGAGGTGTACGAACATATCGCTAATCTGGTCATAGTTAAAAATCGAGTCGAAGGCGTCAGGTATTTGATAGATTGCCTCCTAAGGTATGGCACGAATCAGGCCTACGAAGCATTCGTTGATAGCCTTGCCAAAGATTACAACTGGCTCTGGGAGAAGTTTGCTACACAATCCAACGGGCCAATGTTTAACGACAGCTTCGAGGACAGCCTTAGCAAAGGCGACGTGCCAAGGCTTCCCGAACACCATGTCAGGAGAAAGGCTGTGGAAACTGAAGTCCTATCCAAGATTAAAGAGTTGACCCGTCACAAGATACTGGTGCTTCACGGTATGCTTGGCAGCGGAAAGACCTGCGTCGCCATCAACGTACTCCGGGACAACCCCGAACTCATAACGAACAATTTCAATGATATTGTCTTTTGGATGAACTTTGCGAATTGCAAGACCGATGACGACATCATCGCTCAACAGAATACCCATTCGCTCTCCTACTACGATCGCACGTGGAACGACTTCAGAGACAGACTGAAGAACCTATTCTCGGAGCCCCCGCTGAAGGAAGGTTTGCTCGTAATGGACGAAGTCAACGATCGGAAATGCGTCGAAGCGTTCGATATCGGTTGCAAGATACTGATCACGACCAGAGATACGGACGTTGTGGCTAATTATCACCCGCAAATCGTTACGGTGGAGAACAGTTTCACAGAGAGGGAGTCCCTAGAACTGTTTGCTTCTTGCTTAGACGAACCTGTATCGAAACTTCCATCGTATGCGAAAGAGCTCAACGAATTATGCAAAGGAAGCCCCTTCCACGTGGCCCTGATCGGTGCCCAGCTCGCAGAAGACAGGGAGAGACTGAAACACGATCGAAGTCATTGGAAATATTACTTGAAGAAATTAAAAAAGAATTTCTTTTCTGTGTGGAAAACGAACAACGATAACCCGATGAAAACTATACAAGTGTGTATAAACTCGTTGAACCCCAACACGCTTGCGATGTTCATGAAACTGGCAGTGCTTCCGGACAGCGTCAAAGTCACCGCTCAAGTCTACAGCAAACTGTGGAACGTAGACGTCAACGAAGTCGAAAACATAACGAAGAAACTCAAGAGCAAGTCTCTGATCATAAAGAACTACGATAGAGATCAAAAAAAGTATTTATACGAAGTGCACGATCTCATAATGAACTATCTAAGGTCTTGTACGCACGAAGAGGAAATGAAGAAGCTACACGACGAACTGTTGAACAGTTACAGATATGATAGCGAAACTGCACCAACGGAGATAGTCGATGACGGATACATAGCCTTCTACATAGGATTTCACATTTTGAAAACGAAAAATTTGCACCAGAAATGGAGTTTGTTCAGTAAGCTGTATTTAGATTTGAGGTTTCTAGGGAATAAAGTCAGACTGACCGGACCGGACGATGTCATGCTGGATCTGCAGAAATACGAAAATTATATTGTGAGAGATGAAATCGACAGAAACTTAGTGTACAGTATAAAAGCGTTTCTAAGCACGCACGGCACAGACCTGCACCACTACCCCTGCACGAACATTGTGCAAAGTATAATACAACACGAAACGAAAGGAATATTGTGTTGTAAGGCTTCGTTAATAGCACGGGATAACTGCGTAAACAACGAATTGTATTTTGAGTTTATGCACGAACATGATGTAGAAGAAATTAAACATTCAACTATCGACGTTAAGGAAGTTATCAAATCTGTTTGCTTCTTGAGAAATTATGTAATTGTTGGGACGTCCAATGGCTTGATAAAGTTCTTCAACATAGAAACTAATAAGCAGAAGAAGGAACTAAAGGGCACCGGTGCCGCCATTAAATGGATAGGCGTCGCGTGCACTAAAGACACGACTATTGTAGCCGCTCTGTCGACGGACGGATATCTCAAACTTTGGTTCGTCGATGACTTCGATGATGACGACAACGCTAATAATCTCGTCGAAGAAGAACCGAACGATGCCTACAACAACTATCCCAGTCCGTTAACATTTGAACCCAAACTGGGACCGATACTAAACTGTCGTTGGACGACCAGCGAAGACTTGTTAATAACTCACACGTCACAAATGATTATACTGTACCGTCCCAAAGGCGCCGAGTATGACGTCATAAGTGAGTTCGACAGGGAACAGAAGCTGCTATGCTGCGTCCCCTGTAACAACGACAAATACATTGCTGTAGCTAGTTTCAACGCCGTATACAGAGTGGACTTGATCGACATTAGAACTAAGCAGAAAGTTGTTTATTTCGAAGAAACAGGTGCCATATTGGATATGCTTGTTGTTCCTGGTACCAATAAAATAATAACGCTGAAACAAAACGAGATAATGGCACACGAGTTCCGGGTAAAGCCTGCTTCGATAAACAGAGGCGGGACGGTTATCGATAGCGGTGCGGTCAAAGCGGATGTCCGGTTCGCGGCGATGGCCGTCAACAACTCGGGCTCGCTGCTGTTCGCGGCCACGGACGATAGCCGGGTCGTTTGTGTCGACTTGAAAACTAACTCAAGAGTTTTCGATATCGAGAACAGAAGGGGCAATGTGGTGTCAATGGCGGTGAGCGAAGTGCTGATGTGGGATGAATTCGAACCGAGCTCCGACGTACTTCTAACCGGTACTGATAGTACCGAAAATTCTGCCAAAGTTTGGTATTTAGACGCTTCATACGTGTCGCAGACTGCACAAAGAAAAGGAAAAGTTCGTCTAACAAGTAAATTCGACGTGAGTTTCCTAAACGCGACAACGCCAACATCTCCGAGCGCCTCGCCTCTGAACAGCGGCGTGGAAACAGTTCACAACCCTCTAAAATCACACCAGTCGTTCACGAACAAGGACCCAGTAAAGAAACCGATTAAAACTACCATGAGCTTGGACAGGAATACATTGAAACCGCTCAATCTCAAAGGAATATGCAACAACAATGAAGGGCTCATACACCCATTACTGGCTGTCGTCGATGATATGAACAATATACAGGTGATGCGTGGTAAGAAAGTCCTAACCGAGATCTTAGAGAAATCTGATGAGAAGATAACAGCCGTCAAGGTATCGCCGTGCAATCACTACATCATGTACGGGCTCAAGTCGGGAAAAGTCAAGAGATACACATTGAGAACCAAGGAGATGACAACTATAATGCACGTTAACAGTCCGGTGCAATACCTGAACTACATCAACAACAGGTTGATGCTGGTCGCGTGGAAGAACCGATGTCTAATGTCGTATAAACTGGGCCACGAGGAGACCTGGAAGACTGAAATGCTACAGGCCGGTAACACGCACCTCGGCTCGCAAGAATCGCAGCTAGGAAGCGATTGGCAGAGTATGAAAATAAGGAACGGCCACTCCGACTTGTCGACGTCGAGCAGCGAGGCCAGCGTGAGCTCCCGCGAGAACCGACTGTTCCACGGCGGGGAGATGAAGGAGCTGTACAAACAGAGCGACCTCGTCGACTGCTTCTGGGTCGCGGACACCGGCCTCATCACGGTCGAGTCGAACGCGGCCATCAAACTGTGGAACAAAGACTGCAAAGTCTCAACCATATTGAACGCGAGGCAAATGGATACTTACATCACGTGCGCCGCTTTCCAGAACAACGTTCTCGTTATATGCGATAGTGAAAACAAAGGATTTCAGTCGTACGAACTAAAATTCGACAACACAATAGATTTGTGCCTCATCCAAGAGTACAAACTGAACAATGTGGTGACGTCATGCGATATCACATCCGACGGCTACATACTAGCGATGGGACTAGACTGTGGTAATGTTGTGCTTTGGAACGTAAAAGGGAAGCGTCAAATCAGTTTACTCAAACACCACAACTCGAGAGTGCAGGCGTGCTCGTTCTCGCCGGTACCGGACCGACTGTACCGGAGCTCCGTGCACTCGCCCGGTGTGACGTCACCGGCGGACGCCGTCGCCGACGACCAGCCTCCACTGGTCCTGGTCACGATGGCTTCAGAGATAGTCTGGTGGAACATCACGTACGTCATACGGATACGAGCGAGTAATAAGTCATTGTGGAGGAGCGGACTCAATGTTATATCGCCAATTGGAACGCCATTAGAGAATCGAGCTGAGAATCACCAGACGACAGAAAATTCGGGCAACGTTAATACCAATTTCTTCTTCAGAGATATGTTCGCAGATAGACATTGTTGGAAGAACATTTGGAAAGGAAAAACATGTAAAGAAGGGTCGAAACGCAAAGAAATATTGGCGTGTATAAAACTATCGGGTATAAACGCGACGAGGTTGTGCCACGACGAGAATTTCTCGTGCTTCGTGACCGTGGACAATCCGGGCCACGTCCACATCATGAACGTTATGAGGGATCTTTGTACGTAG

Protein

MDLKNRKLLQHNQQAIIKDLDVQYILDELYTKQAISSEVYEHIANLVIVKNRVEGVRYLIDCLLRYGTNQAYEAFVDSLAKDYNWLWEKFATQSNGPMFNDSFEDSLSKGDVPRLPEHHVRRKAVETEVLSKIKELTRHKILVLHGMLGSGKTCVAINVLRDNPELITNNFNDIVFWMNFANCKTDDDIIAQQNTHSLSYYDRTWNDFRDRLKNLFSEPPLKEGLLVMDEVNDRKCVEAFDIGCKILITTRDTDVVANYHPQIVTVENSFTERESLELFASCLDEPVSKLPSYAKELNELCKGSPFHVALIGAQLAEDRERLKHDRSHWKYYLKKLKKNFFSVWKTNNDNPMKTIQVCINSLNPNTLAMFMKLAVLPDSVKVTAQVYSKLWNVDVNEVENITKKLKSKSLIIKNYDRDQKKYLYEVHDLIMNYLRSCTHEEEMKKLHDELLNSYRYDSETAPTEIVDDGYIAFYIGFHILKTKNLHQKWSLFSKLYLDLRFLGNKVRLTGPDDVMLDLQKYENYIVRDEIDRNLVYSIKAFLSTHGTDLHHYPCTNIVQSIIQHETKGILCCKASLIARDNCVNNELYFEFMHEHDVEEIKHSTIDVKEVIKSVCFLRNYVIVGTSNGLIKFFNIETNKQKKELKGTGAAIKWIGVACTKDTTIVAALSTDGYLKLWFVDDFDDDDNANNLVEEEPNDAYNNYPSPLTFEPKLGPILNCRWTTSEDLLITHTSQMIILYRPKGAEYDVISEFDREQKLLCCVPCNNDKYIAVASFNAVYRVDLIDIRTKQKVVYFEETGAILDMLVVPGTNKIITLKQNEIMAHEFRVKPASINRGGTVIDSGAVKADVRFAAMAVNNSGSLLFAATDDSRVVCVDLKTNSRVFDIENRRGNVVSMAVSEVLMWDEFEPSSDVLLTGTDSTENSAKVWYLDASYVSQTAQRKGKVRLTSKFDVSFLNATTPTSPSASPLNSGVETVHNPLKSHQSFTNKDPVKKPIKTTMSLDRNTLKPLNLKGICNNNEGLIHPLLAVVDDMNNIQVMRGKKVLTEILEKSDEKITAVKVSPCNHYIMYGLKSGKVKRYTLRTKEMTTIMHVNSPVQYLNYINNRLMLVAWKNRCLMSYKLGHEETWKTEMLQAGNTHLGSQESQLGSDWQSMKIRNGHSDLSTSSSEASVSSRENRLFHGGEMKELYKQSDLVDCFWVADTGLITVESNAAIKLWNKDCKVSTILNARQMDTYITCAAFQNNVLVICDSENKGFQSYELKFDNTIDLCLIQEYKLNNVVTSCDITSDGYILAMGLDCGNVVLWNVKGKRQISLLKHHNSRVQACSFSPVPDRLYRSSVHSPGVTSPADAVADDQPPLVLVTMASEIVWWNITYVIRIRASNKSLWRSGLNVISPIGTPLENRAENHQTTENSGNVNTNFFFRDMFADRHCWKNIWKGKTCKEGSKRKEILACIKLSGINATRLCHDENFSCFVTVDNPGHVHIMNVMRDLCT

Uniprot

A0A2A4JWY0 A0A194RAV4 A0A3S2TKT6 A0A023J7Q5 A0A3G1ZL41 A0A194PN06 + More
A0A212EVA7 A0A1Y1N3Z0

Pubmed

26354079 22118469 28004739

EMBL

NWSH01000423 PCG76501.1 KQ460473 KPJ14415.1 RSAL01000076 RVE48846.1 + More
KC588901 KF318722 AHB86312.1 AHH02583.1 MG735332 AYM00395.1 KQ459600 KPI94114.1 AGBW02012218 OWR45425.1 GEZM01013424 JAV92574.1

Proteomes

UP000218220 UP000053240 UP000283053 UP000053268 UP000007151

Pfam

PF00619   CARD        + More
PF17908   APAF1_C
PF00931   NB-ARC
PF00400   WD40

Interpro

IPR001315   CARD        + More
IPR036388   WH-like_DNA-bd_sf
IPR015943   WD40/YVTN_repeat-like_dom_sf
IPR041452   APAF1_C
IPR011047   Quinoprotein_ADH-like_supfam
IPR001680   WD40_repeat
IPR011029   DEATH-like_dom_sf
IPR002182   NB-ARC
IPR027417   P-loop_NTPase
IPR036322   WD40_repeat_dom_sf
IPR019775   WD40_repeat_CS
IPR017986   WD40_repeat_dom

SUPFAM

SSF52540   SSF52540        + More
SSF47986   SSF47986
SSF50998   SSF50998
SSF50978   SSF50978

Gene 3D

1.10.10.10 2.130.10.10

ProteinModelPortal

A0A2A4JWY0 A0A194RAV4 A0A3S2TKT6 A0A023J7Q5 A0A3G1ZL41 A0A194PN06 + More
A0A212EVA7 A0A1Y1N3Z0

PDB

5WVE E-value=3.23422e-36, Score=386

KEGG

100529085 K02084 apoptotic protease-activating factor | (RefSeq) Apaf-1; Apaf-1 protein

PATHWAY

04214 Apoptosis - fly - Bombyx mori (domestic silkworm)
04215 Apoptosis - multiple species - Bombyx mori (domestic silkworm)

GO

GO:0043531 GO:0042981 GO:0008233 GO:0005515 GO:0051276 GO:0016491 GO:0016620 GO:0016787 GO:0003676 GO:0015930

Length:

1494

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.21143

Exp number, first 60 AAs:

5e-05

Total prob of N-in:

0.00516

outside

1 - 1494

Pi

279.923009

Theta

186.222498

Tajima's D

1.600495

CLR

0.305282

CSRT

0.808159592020399

Interpretation

Uncertain

Sequence

Summary

Ontologies

Topology

Population Genetic Test Statistics