SGID Silkworm Genome Informatics Database
Gene
KWMTBOMO13668  Validated by peptides from experiments
Pre Gene Modal
BGIBMGA011029
Annotation
PREDICTED:_acetyl-CoA_acetyltransferase?_mitochondrial_[Papilio_polytes]
Location
Bomo_Chr23(-):5364410-5366800      View in EpiBrowser
Location in the cell
Cytoplasmic   Reliability : 1.23 Mitochondrial   Reliability : 1.529
 

Sequence

CDS
ATGAAGCCAATATTTACAGCAATGGCAGCATTCTCGACCAAAGTTTCCCTCAACGAAGTAGTAATTGCATCAGCAGTTAGAACTCCTATGGGTTCTTTCCGAGGGAGCTTATCTAGTTTATCAGCATCAGAATTAGGCGCTGTCGCTGTTAACGCGGCAATCGAAAGAGCCGGTATTCCTAAAGAAGAAATAAAAGAGGTCTACATTGGCAATGTTTGTTCTGCAAATTTGGGCCAAGCACCTGCAAGACAAGCTGTAATATTTGCAGGTTTGCCAAAAAGTACCATATGTACAACTGTAAACAAAGTATGTGCCTCTGGCATGAAATCTATAATGTTGGCAGCACAAGGTCTACAAACTGGAGCCCAAGATATAATACTTGCTGGTGGGATGGAATCTATGTCAAATGTACCTTTTTATTTGAAGAGAGGTGAAACTTCATATGGAGGAATGCAGTTAGTTGATGGAATAGTGTTTGATGGGCTCACAGATGTGTACAACAAATTTCACATGGGAAATTGTGCTGAAAACACAGCAAAAAAATTACAAATTACTAGACAAGATCAAGATGAATATGCTGTCAATAGTTACAAGAGAAGTGCAGCTGCTTATGAAGCTAAAGCTTTTGTTGATGAACTTGTACCAGTACCCGTTCCACAGAAAAGAGGGGCTCCTGTAATATTTGCTGAAGATGAAGAGTATAAAAGAGTTAATTTTGAAAAGTTTACAAAATTGTCTACGGTATTCCAAAAGGAAAATGGCACTGTTACTGCAGGCAATGCTTCAACATTAAATGATGGAGCTGCAGCTTTAGTGTTAATGACGGCTGATGCCGCTAAAAGATTAAATGTCAAGCCGATTGCCCGAATTGTTGGATTTGCTGATGGGGAATGTGATCCCATTGACTTCCCAATAGCACCAGCGGTTGCCATTCCTAAATTATTAGAGAAGACTGGTGTCAGGAAGGAAGATGTTGCATTGTGGGAGATAAATGAAGCTTTCAGTGTTGTTGCTGTTGCAAATCAAAAATTATTAGGATTAGATCCATCAAAAATTAATGTACATGGTGGAGCTGTCAGTTTGGGTCATCCAATTGGTATGTCTGGAGCTCGCATTGTTGTACATCTGTGCCATGCTTTAAAAAAAGGAGAAAAGGGAGTTGCTTCAATTTGTAATGGTGGAGGTGGTGCATCATCTGTAATGATTGAAAAAATAGCCGAAACTCCAGAAGAGCTACCGGTTTTGACATTTTATACCAAAGATCCATGTGGTCTCTGTGATTTAGTTATGGAAGACCTTGAACCATATAAAAAGAGACTTATCATACAAAAAATTGATATCACTCAAAAAGAAAATTTGCGGTGGTTACGCCTTTATAGACTTGAAATACCAGTCTTATTCTTGAATGGACATTTTTTATGTAAACATAAGTTAAACAAAGATCTTCTTGAGAAAAAGTTGACATTAATTGAAATAGAAAAAAAACAAACATCATAA
Protein
MKPIFTAMAAFSTKVSLNEVVIASAVRTPMGSFRGSLSSLSASELGAVAVNAAIERAGIPKEEIKEVYIGNVCSANLGQAPARQAVIFAGLPKSTICTTVNKVCASGMKSIMLAAQGLQTGAQDIILAGGMESMSNVPFYLKRGETSYGGMQLVDGIVFDGLTDVYNKFHMGNCAENTAKKLQITRQDQDEYAVNSYKRSAAAYEAKAFVDELVPVPVPQKRGAPVIFAEDEEYKRVNFEKFTKLSTVFQKENGTVTAGNASTLNDGAAALVLMTADAAKRLNVKPIARIVGFADGECDPIDFPIAPAVAIPKLLEKTGVRKEDVALWEINEAFSVVAVANQKLLGLDPSKINVHGGAVSLGHPIGMSGARIVVHLCHALKKGEKGVASICNGGGGASSVMIEKIAETPEELPVLTFYTKDPCGLCDLVMEDLEPYKKRLIIQKIDITQKENLRWLRLYRLEIPVLFLNGHFLCKHKLNKDLLEKKLTLIEIEKKQTS

Summary

Similarity
Belongs to the thiolase-like superfamily. Thiolase family.
Uniprot
A0A194PSL1   A0A212EV98   A0A194R9U5   A0A2H1V442   A0A088M985   A0A0L7K3X0   + More
A0A1Q3G5I6   H9JNC6   A5A797   D6WAN7   U4UXZ8   S4PX78   A0A026WB42   A0A0L7RB84   E2A7A4   A0A232F866   I4DNZ9   A0A195CZR7   A0A1V0M897   A0A151X3E1   A0A084WCJ7   A0A195ERW0   A0A182Y6Z9   A0A182J461   E2BF82   A0A195BR39   W5JHX2   A0A154PGM7   A0A182H3Q8   A0A182QXB2   A0A182SRZ0   A0A182FTX4   A0A2A4JWV9   A0A182N3D0   A0A182RLJ8   A0A182ML35   A0A182W1L8   A0A291P161   A0A291P121   A0A2H4UZK2   A0A088A7V7   A0A182U9K0   A0A1B6J2A8   A0A182HY56   A0A182WXI1   A0A182UML4   A0A182LHA8   B0XJ38   A0A182P2N2   A0A195EF02   A0A067QU33   A0A1B6D1S8   A0A336LLV7   A0A2A3EPK3   A0A1J1J5R4   A0A1L8DYX1   A0A1L8DZ47   K7ISJ1   A0A023ETB1   I1VJ17   A0A1L8DZ78   A0A1L8DYQ0   F4WQU2   A0A158NRR5   A0A1W4XE81   A0A0H4IRH6   A0A0M8ZZA5   A0A0C9QQV1   A0A1Y1M1H4   Q56CY6   A0A2M3ZH75   A0A2M3ZH66   A0A2H1V0U2   A0A1V0M8A0   A0A0P6H5P3   A0A2M4ADC3   A0A2M4BPR8   A0A0P5IFM7   A0A0P6D8S6   A0A2M4ADB4   Q175J7   A0A1B6GLL4   A0A0P5QQV0   A0A0P5XC51   A0A1S4FE42   T1E9X1   A0A2M4AD81   A0A0P5IJ91   A0A1B6FXX3   A0A0P0DZ45   A0A0L0BRE9   A0A1B6E2E7   A0A1B6J834   A0A1A9X5A9   A0A2M4BPJ3   A0A0P5GAD7   A0A0P5X6I4   A0A0P5GQD5   U5ETW3   T1PDZ7  
Pubmed
26354079    22118469    26385554    26227816    19121390    17628279    + More
18362917    19820115    23537049    23622113    24508170    30249741    20798317    28648823    22651552    28349297    24438588    25244985    20920257    23761445    26483478    28986331    29185447    20966253    24845553    20075255    24945155    22516182    21719571    21347285    26899871    28004739    17510324    26445454    26108605    25315136   
EMBL
KQ459600    KPI94110.1    AGBW02012218    OWR45428.1    KQ460473    KPJ14412.1    + More
ODYU01000581    SOQ35615.1    KJ579206    AIN34682.1    JTDY01011334    KOB56897.1    GEYN01000174    JAV44815.1    BABH01019456    AB274988    BAF62106.1    KQ971312    EEZ97970.1    KB632410    ERL95190.1    GAIX01005513    JAA87047.1    KK107347    QOIP01000007    EZA52249.1    RLU20939.1    KQ414617    KOC68080.1    GL437329    EFN70601.1    NNAY01000759    OXU26649.1    AK403218    BAM19639.1    KQ977041    KYN06116.1    KU755506    ARD71216.1    KQ982562    KYQ54912.1    ATLV01022681    KE525335    KFB47941.1    KQ981993    KYN30916.1    GL447952    EFN85668.1    KQ976424    KYM88603.1    ADMH02001457    ETN62505.1    KQ434899    KZC11011.1    JXUM01107962    JXUM01107963    JXUM01107964    JXUM01107965    JXUM01107966    JXUM01107967    JXUM01107968    KQ565188    KXJ71243.1    AXCN02001111    NWSH01000423    PCG76497.1    AXCM01006132    MF706171    ATJ44598.1    MF687639    ATJ44565.1    KY971766    AUA18033.1    GECU01014391    JAS93315.1    APCN01004493    DS233428    EDS29933.1    KQ978983    KYN26818.1    KK853270    KDR09162.1    GEDC01017649    JAS19649.1    UFQS01000042    UFQT01000042    SSW98319.1    SSX18705.1    KZ288203    PBC33434.1    CVRI01000073    CRL07747.1    GFDF01002414    JAV11670.1    GFDF01002385    JAV11699.1    GAPW01001060    JAC12538.1    JQ855638    AFI45001.1    GFDF01002492    JAV11592.1    GFDF01002491    JAV11593.1    GL888275    EGI63455.1    ADTU01024274    KP689334    AKO63316.1    KQ435793    KOX74160.1    GBYB01006109    JAG75876.1    GEZM01042666    JAV79742.1    AY966010    AAX78436.1    GGFM01007037    MBW27788.1    GGFM01007027    MBW27778.1    ODYU01000159    SOQ34458.1    KU755503    ARD71213.1    GDIQ01036854    JAN57883.1    GGFK01005401    MBW38722.1    GGFJ01005861    MBW55002.1    GDIQ01214056    GDIQ01109284    JAK37669.1    GDIQ01081802    JAN12935.1    GGFK01005391    MBW38712.1    CH477399    EAT41757.1    GECZ01006479    JAS63290.1    GDIQ01131134    JAL20592.1    GDIP01074264    LRGB01000115    JAM29451.1    KZS20723.1    GAMD01001528    JAB00063.1    GGFK01005425    MBW38746.1    GDIQ01214057    JAK37668.1    GECZ01014721    GECZ01003669    JAS55048.1    JAS66100.1    KT261712    ALJ30252.1    JRES01001480    KNC22563.1    GEDC01005219    JAS32079.1    GECU01034670    GECU01018604    GECU01012360    JAS73036.1    JAS89102.1    JAS95346.1    GGFJ01005864    MBW55005.1    GDIQ01247346    JAK04379.1    GDIP01088713    JAM15002.1    GDIQ01241102    JAK10623.1    GANO01002599    JAB57272.1    KA646977    AFP61606.1   
Proteomes
UP000053268    UP000007151    UP000053240    UP000037510    UP000005204    UP000007266    + More
UP000030742    UP000053097    UP000279307    UP000053825    UP000000311    UP000215335    UP000078542    UP000075809    UP000030765    UP000078541    UP000076408    UP000075880    UP000008237    UP000078540    UP000000673    UP000076502    UP000069940    UP000249989    UP000075886    UP000075901    UP000069272    UP000218220    UP000075884    UP000075900    UP000075883    UP000075920    UP000005203    UP000075902    UP000075840    UP000076407    UP000075903    UP000075882    UP000002320    UP000075885    UP000078492    UP000027135    UP000242457    UP000183832    UP000002358    UP000007755    UP000005205    UP000192223    UP000053105    UP000008820    UP000076858    UP000037069    UP000091820    UP000095301   
PRIDE
H9JNC6    A5A797   
Pfam
PF05768   DUF836        + More
PF02803   Thiolase_C
PF00108   Thiolase_N
Interpro
IPR002155   Thiolase        + More
IPR020613   Thiolase_CS       
IPR020610   Thiolase_AS       
IPR020616   Thiolase_N       
IPR016039   Thiolase-like       
IPR020615   Thiolase_acyl_enz_int_AS       
IPR036249   Thioredoxin-like_sf       
IPR008554   Glutaredoxin-like       
IPR020617   Thiolase_C       
IPR002109   Glutaredoxin       
SUPFAM
SSF53901   SSF53901        + More
SSF52833   SSF52833       
Gene 3D
3.40.47.10    
CDD
cd00751  thiolase
ProteinModelPortal
A0A194PSL1   A0A212EV98   A0A194R9U5   A0A2H1V442   A0A088M985   A0A0L7K3X0   + More
A0A1Q3G5I6   H9JNC6   A5A797   D6WAN7   U4UXZ8   S4PX78   A0A026WB42   A0A0L7RB84   E2A7A4   A0A232F866   I4DNZ9   A0A195CZR7   A0A1V0M897   A0A151X3E1   A0A084WCJ7   A0A195ERW0   A0A182Y6Z9   A0A182J461   E2BF82   A0A195BR39   W5JHX2   A0A154PGM7   A0A182H3Q8   A0A182QXB2   A0A182SRZ0   A0A182FTX4   A0A2A4JWV9   A0A182N3D0   A0A182RLJ8   A0A182ML35   A0A182W1L8   A0A291P161   A0A291P121   A0A2H4UZK2   A0A088A7V7   A0A182U9K0   A0A1B6J2A8   A0A182HY56   A0A182WXI1   A0A182UML4   A0A182LHA8   B0XJ38   A0A182P2N2   A0A195EF02   A0A067QU33   A0A1B6D1S8   A0A336LLV7   A0A2A3EPK3   A0A1J1J5R4   A0A1L8DYX1   A0A1L8DZ47   K7ISJ1   A0A023ETB1   I1VJ17   A0A1L8DZ78   A0A1L8DYQ0   F4WQU2   A0A158NRR5   A0A1W4XE81   A0A0H4IRH6   A0A0M8ZZA5   A0A0C9QQV1   A0A1Y1M1H4   Q56CY6   A0A2M3ZH75   A0A2M3ZH66   A0A2H1V0U2   A0A1V0M8A0   A0A0P6H5P3   A0A2M4ADC3   A0A2M4BPR8   A0A0P5IFM7   A0A0P6D8S6   A0A2M4ADB4   Q175J7   A0A1B6GLL4   A0A0P5QQV0   A0A0P5XC51   A0A1S4FE42   T1E9X1   A0A2M4AD81   A0A0P5IJ91   A0A1B6FXX3   A0A0P0DZ45   A0A0L0BRE9   A0A1B6E2E7   A0A1B6J834   A0A1A9X5A9   A0A2M4BPJ3   A0A0P5GAD7   A0A0P5X6I4   A0A0P5GQD5   U5ETW3   T1PDZ7  
PDB
2IBY     E-value=5.6798e-135,     Score=1233

Ontologies

KEGG
100101202    K00626 acetyl-CoA C-acetyltransferase [EC:2.3.1.9] | (RefSeq) Aact, Aact_bm; acetoacetyl-CoA thiolas
PATHWAY
00071    Fatty acid degradation - Bombyx mori (domestic silkworm)
00072    Synthesis and degradation of ketone bodies - Bombyx mori (domestic silkworm)
00280    Valine, leucine and isoleucine degradation - Bombyx mori (domestic silkworm)
00310    Lysine degradation - Bombyx mori (domestic silkworm)
00380    Tryptophan metabolism - Bombyx mori (domestic silkworm)
00620    Pyruvate metabolism - Bombyx mori (domestic silkworm)
00630    Glyoxylate and dicarboxylate metabolism - Bombyx mori (domestic silkworm)
00640    Propanoate metabolism - Bombyx mori (domestic silkworm)
00650    Butanoate metabolism - Bombyx mori (domestic silkworm)
00900    Terpenoid backbone biosynthesis - Bombyx mori (domestic silkworm)
01100    Metabolic pathways - Bombyx mori (domestic silkworm)
01200    Carbon metabolism - Bombyx mori (domestic silkworm)
01212    Fatty acid metabolism - Bombyx mori (domestic silkworm)
GO
GO:0016747   GO:0003985   GO:0006635   GO:0005739   GO:0003988   GO:0005623   GO:0009055   GO:0045454   GO:0015035   GO:0003824   GO:0008152   GO:0051276   GO:0016491   GO:0016620   GO:0016787   GO:0003676   GO:0015930  

Topology

Length:
498
Number of predicted TMHs:
0
Exp number of AAs in TMHs:
0.0883599999999999
Exp number, first 60 AAs:
0.05946
Total prob of N-in:
0.00492
outside
1  -  498
 
 

Population Genetic Test Statistics

Pi
278.925506
Theta
208.942146
Tajima's D
1.168368
CLR
0
CSRT
0.703414829258537
Interpretation
Uncertain
Peptides ×
Source Sequence Identity Evalue
26280517 AGIPKEEIK 96.30 8e-12
26822097 IVVHICHAIK 100.00 4e-10
26280517 IVGCVQDHAR 100.00 4e-10
25044914 IVGENITIQGNIDPQDIYK 100.00 4e-10
28467696 IVGEINPIATSTDIVITITK 100.00 4e-10
28556443 IVGFADGECDPIDFPIAPAVAIPK 100.00 4e-10
28556443 INVHGGAVSLGHPIGMSGAR 100.00 4e-10
28556443 INVHGGAVSLGHPIGMSGAR 100.00 4e-10
28556443 INVHGGAVSLGHPIGMSGAR 100.00 4e-10
26280517 EEIISMSIGK 95.45 2e-08
25044914 EEIIYVVCVRPNK 95.45 2e-08
28467696 EEIGITDSIVR 95.45 2e-08
28556443 INVHGGAVSLGHPIGMSGAR 100.00 6e-08
28556443 INVHGGAVSLGHPIGM 100.00 6e-08
28556443 GVASICNGGGGASSVMIEK 100.00 6e-08
28556443 INVHGGAVSLGHPIGM 100.00 6e-08
26280517 KCESGYDVNYKQDK 95.45 9e-08
25044914 KEDINFESK 95.45 9e-08
28556443 EVYIGNVCSANLGQAPAR 100.00 3e-06
28556443 EVYIGNVCSANLGQAPAR 100.00 3e-06
28556443 ENGTVTAGNASTLNDGAAALVLMTADAAK 100.00 3e-06
28556443 EVYIGNVCSANLGQAPAR 100.00 3e-06
28556443 ENGTVTAGNASTLNDGAAALVLMTADAAK 100.00 3e-06
28556443 ENGTVTAGNASTLNDGAAALVLMTADAAK 100.00 3e-06
26280517 GTNINDSGDNAAQNDVTK 100.00 1e-05
28467696 GVARPPPAPTSTPGGRPR 100.00 1e-05
28556443 GVASICNGGGGASSVMIEK 100.00 1e-05
28556443 GVASICNGGGGASSVMIEK 100.00 1e-05
28556443 GSLSSLSASELGAVAVNAAIER 100.00 1e-05
28556443 GVASICNGGGGASSVMIEK 100.00 1e-05
28556443 GSLSSLSASELGAVAVNAAIER 100.00 1e-05
28556443 GSLSSLSASELGAVAVNAAIER 100.00 1e-05
28556443 GVASICNGGGGASSVMIEK 100.00 3e-05
28556443 GVASICNGGGGASSVMIEK 100.00 3e-05
26280517 RGAECGAVGHCTATVWEK 100.00 2e-04
26280517 STFSGYSNIEVR 100.00 3e-04
28556443 ENGTVTAGNASTLNDGAAALVLMTADAAK 100.00 4e-04
28556443 AFVDELVPVPVPQK 100.00 4e-04
28556443 AFVDELVPVPVPQK 100.00 4e-04
28556443 AFVDELVPVPVPQK 100.00 4e-04
28556443 GGMESMSNVPFYLK 100.00 8e-04
28556443 GAPVIFAEDEEYKR 100.00 8e-04
28556443 GAPVIFAEDEEYKR 100.00 8e-04
28556443 LLGLDPSK 100.00 8e-04
26280517 FECISDGICIPR 100.00 0.002
26280517 QDGESEPYAEEAR 100.00 0.003
28467696 QDQDEYAVNSYK 100.00 0.003
26822097 STICTTVNK 100.00 0.003
26280517 GAPPIIDVASIIAR 100.00 0.003
27102218 AFVDEIVPVPVPQKR 100.00 0.003
28467696 GAPNMINTFWEQSTVDIAR 100.00 0.003
28556443 GAPVIFAEDEEYKR 100.00 0.003
28556443 GAPVIFAEDEEYK 100.00 0.003
28556443 EVYIGNVCSANLGQAPAR 100.00 0.003
28556443 EVYIGNVCSANLGQAPAR 100.00 0.003
26822097 GAPVIFAEDEEYKR 100.00 0.006
26280517 FCAQGCSAIADTGTSIIAGPSK 100.00 0.006
25044914 FHISVSDDNSGR 100.00 0.006
28556443 EVYIGNVCSANLGQAPAR 100.00 0.006
28556443 GAPVIFAEDEEYK 100.00 0.006
28556443 AFVDELVPVPVPQK 100.00 0.009
28556443 AFVDELVPVPVPQK 100.00 0.009
28556443 AFVDELVPVPVPQK 100.00 0.009
28556443 AFVDELVPVPVPQK 100.00 0.009
28556443 AFVDELVPVPVPQK 100.00 0.009
28556443 QDQDEYAVNSYK 100.00 0.009
28556443 AFVDELVPVPVPQK 100.00 0.009
28556443 AFVDELVPVPVPQK 100.00 0.009
28556443 AFVDELVPVPVPQK 100.00 0.009
28556443 AFVDELVPVPVPQK 100.00 0.009
28556443 GGMESMSNVPFYLK 100.00 0.009
28556443 VFNTWMGDPGK 100.00 0.009
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