Gene

KWMTBOMO13600  Validated by peptides from experiments

Pre Gene Modal

BGIBMGA010958

Annotation

Uncharacterized_protein_OBRU01_08225_[Operophtera_brumata]

Location

Bomo_Chr23(-):2495247-2497863      View in EpiBrowser

Full name

Nuclear pore complex protein       + More
Nuclear pore complex protein Nup107      

Alternative Name

Nucleoporin Nup107

Location in the cell

Cytoplasmic   Reliability : 2.173

CDS

ATGGATAATACTTTGCAACTACATTCAACACAGTATACTCCTTTAAGAAATAAGAGAAGCCGACATTTACTACAGAGAGAAGAGACGTTAAATGTTTCGCCTATTTTGAACGATACTTCTATTTTTAAAAACTTAAATGATTCGAGTTTACGGCATGTACTTGATGAATCTTCCATATTGGCGAATCCCAGTAGCACGGGAGATCATTTGAGCGAAGAATTCTTCGAGATAATACAAAGCAGTAGACCTAGCAGTGTTTTAGATACATTAGCAAGGTTAGCTCAGGTATGTTGTGATTCGTTAGAGTTAATCGAGCCATGGAACAGATATAACGTCCACAACTACTGGTTGGCAGAGGAAGCCAACACATGGAAACTAATACATTGCCTGTACGCAGATTCAATCTCAGAACATCCAGAGTCTTTGGAAAATTTAGTTACTGAAGCAACACTATCACAGCAGAGCTTAGTGAATGCTCTATTTAGAAGTGATTCTGAACTGAGACTGTTGCAGCTTCTGGTAGACTGGTTGGAAGCAACTGCTGCTTATCAAGAGGAAGCGACAAAAACTTCAGCACCTGTCATTGGAAATAACATACACTGGGGCAACACTTTACATGAACTGCTGATTGGAAATAGTCTATTCAACAAAGAAAAAAACAAGTCTCTAGTCACATGTATGGATCCAGATGCACCAAGAAGACAAAATAAATCTATACACTCTGATGATATGAAAGATGACAGCGATTTATGTAAACGCATATTTACTGAAGTCCGTTGTGGTAAATTTCAAGAAGCAGTCTCATTATGCATAAGTGCTGGTCAAGCATGGCGAGGAGCAGTACTACAAGGTTGGAAATTATTACATTATTTGCCCAAAGATGATCCAACTGATCCATTAGAAATTCAAGGGAATCCTTCAAGAGACCTTTGGAAATGGTGTGCCCTAGGAATTGCTAATTGTGCATCTGAAAATATCTACTACAGAGCGACAATTGGTATTTTGAGTGGCCACCTGCCTAGTGCACTTCTAGCTTGTCAAGGTAGCTGGGAAGACATTCTATGGGCTCATTTGAAAATACAAATAGAAGTTAGAGTTGACAAGTTTCTCCATGAACATCATTTAACTGTTGATGCTAACACTACACCTTCAGATGTGCTGGACCTATTACAAGCTGAATTTCAAACAGATGAAATATCTTTACAGCAAGTATTTAGTGCAGTAAAGTCTCTGATGGATGGAAAACGTGAATCGAACTATCAGTTGTGTCAGCGTTATTTAATGCTTGGTCAAGTAAGAACAATAATGTTAAATTCATTAGAATGGCTAGAAAATGCTAATGAGAGGTTTATTCGATTTTTAGCACATCTCATATTAGTATTGAGACAAATGGGTAAAGATCCTCAGCATGATGTTGGTGACCAAGTCTTGGAAAAGTATGTGACATTACTTACCATTAGATTGGTTGATGGATCTGTGGAGTCCCCAGAGCTTATAGCATATTACACTTCTACAGTTCCAGCCGAAAAACAAATCATTCTGTATGCAAACTTTATGGACCAAATTCACAAAAGTGATTATAGGCAAGGTGTTGTAAAAGCTGGGTTGGATGCTGGAATCGATGTTGGTGCATCAGCTCGCGTGGCTATTAAGAAAGCTATTGCAGATATACAACAAGGATATGGAAATGTAGAATTGAACTTCACACAGACAAGTGTTATAGAAAAGGATAAAACATTGATATCCAAAGTTATTTCTTCTTTAGAATGGTTGGCTTTAGTTGACAATCAGCTTGAAGAAGCACTATGGTTGAATAATGCAATGATCAGAACATTTATATTCATTGGAAACACTGATGCTGCCAATGCATGTCTGACTAGCTTCAACAAAATGTTTTCTAACTTTATAAACACAGTTGATTCAAGTACCTCTGAACTAAGAGAACATTTGTGTTTAAAAGCATACTTGGATGCTCTCGAGGGATTTGCAACTTGGTATAGACATTTTATAAGTGGACAACCTAAAGATGTGCAGCCATTACCACCAGATGCAACATTTTCTGATAAAGTATATCATGAACAGCAATGTGCACAAGTTGAAAAGAAGAAAGCAATATGGATTAATGCAGTTTCACATCAATCAAGACATACCAAAAGCTTACTATACAATGTTTTACTGTTTCCAGGAGGTTGGTTGCAAGATGAGAGTGATAGTACATCATCAGACAATTTCAACCAGGAAGAGAAAACAGAAAGATTAAAACAGTTGGACACCCTTAGACGACTTTGTGTGCCAGAAATTGTGATTTTATTACTAAAGATTTTACAGAGTAATGAGGATATTGAGAGTCACAAGGAAGCCATTAAATTGGGCAACTTAATTGCTGCAGAAAATAGAGCTCTATATCAAGTGTTCAACAGAAGTAAGCTGATGGAGATTTTGGAGAGGATCAAGGAGTCATCTCTGTTCCTTATGGAAAAAGGAACAGACATTTTAGGTTTTGAAATAAGGGAATAA

Protein

MDNTLQLHSTQYTPLRNKRSRHLLQREETLNVSPILNDTSIFKNLNDSSLRHVLDESSILANPSSTGDHLSEEFFEIIQSSRPSSVLDTLARLAQVCCDSLELIEPWNRYNVHNYWLAEEANTWKLIHCLYADSISEHPESLENLVTEATLSQQSLVNALFRSDSELRLLQLLVDWLEATAAYQEEATKTSAPVIGNNIHWGNTLHELLIGNSLFNKEKNKSLVTCMDPDAPRRQNKSIHSDDMKDDSDLCKRIFTEVRCGKFQEAVSLCISAGQAWRGAVLQGWKLLHYLPKDDPTDPLEIQGNPSRDLWKWCALGIANCASENIYYRATIGILSGHLPSALLACQGSWEDILWAHLKIQIEVRVDKFLHEHHLTVDANTTPSDVLDLLQAEFQTDEISLQQVFSAVKSLMDGKRESNYQLCQRYLMLGQVRTIMLNSLEWLENANERFIRFLAHLILVLRQMGKDPQHDVGDQVLEKYVTLLTIRLVDGSVESPELIAYYTSTVPAEKQIILYANFMDQIHKSDYRQGVVKAGLDAGIDVGASARVAIKKAIADIQQGYGNVELNFTQTSVIEKDKTLISKVISSLEWLALVDNQLEEALWLNNAMIRTFIFIGNTDAANACLTSFNKMFSNFINTVDSSTSELREHLCLKAYLDALEGFATWYRHFISGQPKDVQPLPPDATFSDKVYHEQQCAQVEKKKAIWINAVSHQSRHTKSLLYNVLLFPGGWLQDESDSTSSDNFNQEEKTERLKQLDTLRRLCVPEIVILLLKILQSNEDIESHKEAIKLGNLIAAENRALYQVFNRSKLMEILERIKESSLFLMEKGTDILGFEIRE

Description

Functions as a component of the nuclear pore complex (NPC).
Plays a role in nuclear pore complex (NPC) assembly and maintenance (PubMed:20547758). Required for nuclear import of Mad (PubMed:20547758). Plays a role in double strand break repair by relocalizing the heterochromatic double strain breaks (DSBs) to the nuclear periphery as part of the homologous recombination (HR) repair process (PubMed:26502056). Regulates cytokinesis during spermatocyte meiosis by maintaining type-B lamin Lam localization to the spindle envelope (PubMed:27402967). Regulates female gonad development and oogenesis (PubMed:26485283).

Subunit

Part of the nuclear pore complex (NPC).

Similarity

Belongs to the nucleoporin Nup84/Nup107 family.

Keywords

Chromosome   Complete proteome   Cytoplasm   Cytoskeleton   DNA damage   DNA repair   Membrane   mRNA transport   Nuclear pore complex   Nucleus   Protein transport   Reference proteome   Translocation   Transport  

Feature

chain  Nuclear pore complex protein Nup107

Uniprot

H9JN55   A0A2W1BT20   A0A2A4JCM5   A0A2H1WXB2   A0A0L7LHG2   A0A3S2PLP7   + More
S4NSF9   A0A212EYN4   A0A0N1INM9   A0A194PSC0   K7JA46   A0A232EMD0   A0A2A3EQE4   A0A088A7R5   A0A310SRX9   E2BC48   A0A0C9PQC7   A0A2J7QXA4   A0A026VZ78   A0A195FX98   A0A151WVV9   A0A151IUU3   A0A067RFT9   A0A195CXE7   A0A0L7RBR0   A0A158P0P6   E2AED4   A0A195B240   E9IYK0   F4X7K9   A0A1J1J708   B0WA49   A0A1Q3EW91   W8BN05   A0A182NRX1   A0A182Q2M3   A0A1B6K5W1   A0A182VZJ0   A0A2S2QGG2   A0A182JZH8   A0A182U7Z2   A0A182PSM0   A0A182R8V4   A0A182WSQ1   A0A182LA06   A0A182V3D2   A0NGZ4   A0A0J7L0L7   A0A182HLK3   A0A182Y3P9   A0A182M125   A0A182GA99   A0A182JEH1   A0A182SF30   A0A1S4F613   Q17E59   A0A034V3E5   A0A1I8MAU6   A0A2H8U0C3   A0A182FNG4   A0A0K8VMV4   A0A1I8QF24   A0A0A1WLX2   W5LFP9   W5NH37   A0A1Y1MF97   W5JL65   A0A3B1IUE3   E0VBQ0   Q5RGI2   A0A084VVU0   J9K298   D6X0X5   A1YK63   A1YK61   Q9V466   A1YK65   A1YK58   H2T401   A0A1A9WZW9   A1YK60   A1YK62   A0JMB3   A1YK57   A1YK54   A2RV69   A1YK69   A0A3B3QJN2   W5U6G6   A0A3B3QKM2   A1YK66   A0A1A9Z7S7   G3N7X8   G3N7X6   A1YK71   A0A3Q3W9F1   A1YK68   A0A3P9A276   A0A3Q3W9E7   A1YK72  

Pubmed

19121390    28756777    26227816    23622113    22118469    26354079    + More
20075255    28648823    20798317    24508170    30249741    24845553    21347285    21282665    21719571    24495485    20966253    12364791    14747013    17210077    25244985    26483478    17510324    25348373    25315136    25830018    25329095    28004739    20920257    23761445    20566863    23594743    24438588    18362917    19820115    17056646    10731132    12537572    10731138    18562695    20547758    26485283    26502056    27402967    21551351    27762356    29240929    23127152    25069045    17994087    22936249   

EMBL

BABH01033319    KZ149909    PZC78199.1    NWSH01002102    PCG69190.1    ODYU01011769    + More
SOQ57703.1    JTDY01001053    KOB75003.1    RSAL01000002    RVE55007.1    RVE55060.1    GAIX01014112    JAA78448.1    AGBW02011467    OWR46602.1    KQ461153    KPJ08644.1    KQ459595    KPI95863.1    AAZX01009429    NNAY01003398    OXU19478.1    KZ288203    PBC33359.1    KQ759879    OAD62237.1    GL447255    EFN86724.1    GBYB01003413    GBYB01005209    JAG73180.1    JAG74976.1    NEVH01009382    PNF33216.1    KK107545    QOIP01000010    EZA49072.1    RLU18091.1    KQ981200    KYN45051.1    KQ982691    KYQ52023.1    KQ980943    KYN11260.1    KK852714    KDR17897.1    KQ977141    KYN05331.1    KQ414617    KOC68273.1    ADTU01005685    GL438828    EFN68186.1    KQ976667    KYM78269.1    GL767018    EFZ14395.1    GL888862    EGI57538.1    CVRI01000070    CRL07254.1    DS231869    EDS40878.1    GFDL01015472    JAV19573.1    GAMC01006368    JAC00188.1    AXCN02000252    GECU01000871    JAT06836.1    GGMS01007646    MBY76849.1    AAAB01008987    EAU75643.3    LBMM01001513    KMQ96166.1    APCN01000909    AXCM01000138    JXUM01155894    KQ572328    KXJ68046.1    CH477285    EAT44760.1    GAKP01022687    JAC36265.1    GFXV01007805    MBW19610.1    GDHF01012131    JAI40183.1    GBXI01014238    JAD00054.1    AHAT01008861    GEZM01033229    JAV84333.1    ADMH02001124    ETN64043.1    DS235035    EEB10806.1    BX897665    ATLV01017297    KE525161    KFB42084.1    ABLF02022012    KQ971372    EFA09537.1    EF057986    ABL84921.1    EF057984    EF057987    ABL84919.1    ABL84922.1    AE014134    AF160938    AAD46878.1    EF057988    ABL84923.1    EF057981    ABL84916.1    EF057983    ABL84918.1    EF057985    ABL84920.1    BC125812    AAI25813.1    EF057980    ABL84915.1    EF057977    ABL84912.1    BC133201    CM004471    AAI33202.1    OCT87487.1    EF057992    ABL84927.1    JT406389    AHH37571.1    EF057989    ABL84924.1    EF057994    ABL84929.1    EF057991    ABL84926.1    EF057995    EF057997    EF057998    CM000361    CM002910    ABL84930.1    ABL84932.1    ABL84933.1    EDX04596.1    KMY89612.1   

Proteomes

UP000005204    UP000218220    UP000037510    UP000283053    UP000007151    UP000053240    + More
UP000053268    UP000002358    UP000215335    UP000242457    UP000005203    UP000008237    UP000235965    UP000053097    UP000279307    UP000078541    UP000075809    UP000078492    UP000027135    UP000078542    UP000053825    UP000005205    UP000000311    UP000078540    UP000007755    UP000183832    UP000002320    UP000075884    UP000075886    UP000075920    UP000075881    UP000075902    UP000075885    UP000075900    UP000076407    UP000075882    UP000075903    UP000007062    UP000036403    UP000075840    UP000076408    UP000075883    UP000069940    UP000249989    UP000075880    UP000075901    UP000008820    UP000095301    UP000069272    UP000095300    UP000018467    UP000018468    UP000000673    UP000009046    UP000000437    UP000030765    UP000007819    UP000007266    UP000000803    UP000005226    UP000091820    UP000186698    UP000261540    UP000092445    UP000007635    UP000261620    UP000265140    UP000000304   

PRIDE

H9JN55    A1YK63    A1YK61    Q9V466    A1YK65    A1YK58    + More
A1YK60    A1YK62    A0JMB3    A1YK57    A1YK54   

Pfam

PF04121   Nup84_Nup100        + More
PF01395   PBP_GOBP
PF05018   DUF667

Interpro

IPR007252   Nup84/Nup107        + More
IPR006170   PBP/GOBP       
IPR036728   PBP_GOBP_sf       
IPR007714   CFA20_dom       

SUPFAM

SSF47565   SSF47565       

Gene 3D

1.10.238.20    

ProteinModelPortal

H9JN55   A0A2W1BT20   A0A2A4JCM5   A0A2H1WXB2   A0A0L7LHG2   A0A3S2PLP7   + More
S4NSF9   A0A212EYN4   A0A0N1INM9   A0A194PSC0   K7JA46   A0A232EMD0   A0A2A3EQE4   A0A088A7R5   A0A310SRX9   E2BC48   A0A0C9PQC7   A0A2J7QXA4   A0A026VZ78   A0A195FX98   A0A151WVV9   A0A151IUU3   A0A067RFT9   A0A195CXE7   A0A0L7RBR0   A0A158P0P6   E2AED4   A0A195B240   E9IYK0   F4X7K9   A0A1J1J708   B0WA49   A0A1Q3EW91   W8BN05   A0A182NRX1   A0A182Q2M3   A0A1B6K5W1   A0A182VZJ0   A0A2S2QGG2   A0A182JZH8   A0A182U7Z2   A0A182PSM0   A0A182R8V4   A0A182WSQ1   A0A182LA06   A0A182V3D2   A0NGZ4   A0A0J7L0L7   A0A182HLK3   A0A182Y3P9   A0A182M125   A0A182GA99   A0A182JEH1   A0A182SF30   A0A1S4F613   Q17E59   A0A034V3E5   A0A1I8MAU6   A0A2H8U0C3   A0A182FNG4   A0A0K8VMV4   A0A1I8QF24   A0A0A1WLX2   W5LFP9   W5NH37   A0A1Y1MF97   W5JL65   A0A3B1IUE3   E0VBQ0   Q5RGI2   A0A084VVU0   J9K298   D6X0X5   A1YK63   A1YK61   Q9V466   A1YK65   A1YK58   H2T401   A0A1A9WZW9   A1YK60   A1YK62   A0JMB3   A1YK57   A1YK54   A2RV69   A1YK69   A0A3B3QJN2   W5U6G6   A0A3B3QKM2   A1YK66   A0A1A9Z7S7   G3N7X8   G3N7X6   A1YK71   A0A3Q3W9F1   A1YK68   A0A3P9A276   A0A3Q3W9E7   A1YK72  

PDB

5A9Q     E-value=2.03693e-89,     Score=842

KEGG

101743073    K14301 nuclear pore complex protein Nup107 | (RefSeq) nuclear pore complex protein Nup107

PATHWAY

03013    RNA transport - Bombyx mori (domestic silkworm)

GO

GO:0006406   GO:0000973   GO:0031965   GO:0017056   GO:0031080   GO:0006606   GO:0005549   GO:0051292   GO:0005635   GO:0000724   GO:0007112   GO:0048137   GO:0007110   GO:1900182   GO:0016363   GO:0005694   GO:0005737   GO:0005819   GO:0008585   GO:0030703   GO:0005643   GO:0006810   GO:0006520   GO:0006508   GO:0008237   GO:0008152   GO:0016787   GO:0003676   GO:0016491   GO:0015930  

PANTHER

PTHR13003  

Subcellular location

Nucleus  
Nuclear pore complex  
Nucleus membrane  
Nucleus envelope   Located on both the cytoplasmic and nuclear sides of the NPC core structure (By similarity). During syncytial embryo and larval neuroblast mitosis localizes to the nuclear envelope in interphase, accumulates in the nucleus in prometaphase, localizes to the spindle envelope in metaphase and then to condensing chromatin in telophase (PubMed:18562695). In spermatocytes, detected in the nuclear matrix by the nuclear envelope in metaphase I, and in the spindle envelope in premeiotic nuclei and during anaphase I (PubMed:27402967). Colocalizes with type-B lamin Lam throughout meiosis I (PubMed:27402967). Unlike in mammals, does not localize to kinetochore (PubMed:18562695, PubMed:27402967).   With evidence from 1 publications.
Cytoplasm   Located on both the cytoplasmic and nuclear sides of the NPC core structure (By similarity). During syncytial embryo and larval neuroblast mitosis localizes to the nuclear envelope in interphase, accumulates in the nucleus in prometaphase, localizes to the spindle envelope in metaphase and then to condensing chromatin in telophase (PubMed:18562695). In spermatocytes, detected in the nuclear matrix by the nuclear envelope in metaphase I, and in the spindle envelope in premeiotic nuclei and during anaphase I (PubMed:27402967). Colocalizes with type-B lamin Lam throughout meiosis I (PubMed:27402967). Unlike in mammals, does not localize to kinetochore (PubMed:18562695, PubMed:27402967).   With evidence from 1 publications.
Cytoskeleton   Located on both the cytoplasmic and nuclear sides of the NPC core structure (By similarity). During syncytial embryo and larval neuroblast mitosis localizes to the nuclear envelope in interphase, accumulates in the nucleus in prometaphase, localizes to the spindle envelope in metaphase and then to condensing chromatin in telophase (PubMed:18562695). In spermatocytes, detected in the nuclear matrix by the nuclear envelope in metaphase I, and in the spindle envelope in premeiotic nuclei and during anaphase I (PubMed:27402967). Colocalizes with type-B lamin Lam throughout meiosis I (PubMed:27402967). Unlike in mammals, does not localize to kinetochore (PubMed:18562695, PubMed:27402967).   With evidence from 1 publications.
Spindle   Located on both the cytoplasmic and nuclear sides of the NPC core structure (By similarity). During syncytial embryo and larval neuroblast mitosis localizes to the nuclear envelope in interphase, accumulates in the nucleus in prometaphase, localizes to the spindle envelope in metaphase and then to condensing chromatin in telophase (PubMed:18562695). In spermatocytes, detected in the nuclear matrix by the nuclear envelope in metaphase I, and in the spindle envelope in premeiotic nuclei and during anaphase I (PubMed:27402967). Colocalizes with type-B lamin Lam throughout meiosis I (PubMed:27402967). Unlike in mammals, does not localize to kinetochore (PubMed:18562695, PubMed:27402967).   With evidence from 1 publications.
Chromosome   Located on both the cytoplasmic and nuclear sides of the NPC core structure (By similarity). During syncytial embryo and larval neuroblast mitosis localizes to the nuclear envelope in interphase, accumulates in the nucleus in prometaphase, localizes to the spindle envelope in metaphase and then to condensing chromatin in telophase (PubMed:18562695). In spermatocytes, detected in the nuclear matrix by the nuclear envelope in metaphase I, and in the spindle envelope in premeiotic nuclei and during anaphase I (PubMed:27402967). Colocalizes with type-B lamin Lam throughout meiosis I (PubMed:27402967). Unlike in mammals, does not localize to kinetochore (PubMed:18562695, PubMed:27402967).   With evidence from 1 publications.
Nucleus matrix   Located on both the cytoplasmic and nuclear sides of the NPC core structure (By similarity). During syncytial embryo and larval neuroblast mitosis localizes to the nuclear envelope in interphase, accumulates in the nucleus in prometaphase, localizes to the spindle envelope in metaphase and then to condensing chromatin in telophase (PubMed:18562695). In spermatocytes, detected in the nuclear matrix by the nuclear envelope in metaphase I, and in the spindle envelope in premeiotic nuclei and during anaphase I (PubMed:27402967). Colocalizes with type-B lamin Lam throughout meiosis I (PubMed:27402967). Unlike in mammals, does not localize to kinetochore (PubMed:18562695, PubMed:27402967).   With evidence from 1 publications.

Length:

838

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.00776999999999999

Exp number, first 60 AAs:

0

Total prob of N-in:

0.00012

outside

1  -  838

 

 

Pi

209.99186

Theta

223.092634

Tajima's D

-0.344145

CLR

7.58345

CSRT

0.28133593320334

Interpretation

Uncertain