Gene

KWMTBOMO13597  Validated by peptides from experiments

Pre Gene Modal

BGIBMGA010959

Annotation

transmembrane_emp24_protein_transport_domain_containing_9_precursor_[Bombyx_mori]

Location

Bomo_Chr23(-):2489353-2491993      View in EpiBrowser

Full name

Transmembrane emp24 domain-containing protein eca      

Alternative Name

Protein eclair

Location in the cell

Cytoplasmic   Reliability : 1.091 Extracellular   Reliability : 1.588

CDS

ATGGAGCTTATTAAATTATCTTCACTATTAGTGATAGCATTGCTTGCCGACTGTGCTTCAGCTTTGTACTTCCACATAGCAGAAGGAGAACGAAAATGTTTTATAGAAGAAATACCTGACGATACCACAGTTATAGTAAATTACAAAGTCGAGTTATACGATCCGAAATCTGGCGGATTCATGCAAACAACACCGGGCATAGGCATGCACGTTGAAGTCCGCGATCCGAATGATAGAATACTGTTGTCTCGAGTCTATTCGTTGGAAGGAATGATCTCATTCACATCCAGCACTCCTGGTGAACATGTAATATGCATGTACTCTAATAGCACTTCATGGTTCAGTGGTTCACAGTTAAGAGTTCATCTTGACATTCAAGTTGGTGAGCATGCTGTAGACTATGCAAATGTTGCACAAAAGGAAAAACTGACCGAACTTCAACTCAGGATTAGACAGTTGCTGGATCAAGTACACCAGATCACAAAGGAGCAGGCTTACCAGAGGCAAAGAGAAGAGCGTTTTCGACAAACATCAGAAAGCACAAACCAGCGAGTGCTCTGGTGGAGTTTGCTACAGACAGGTGTCCTTGTCATCATCGGTTACTGGCAGATGAGACATCTCAAGAGCTTTTTTGAGGCTAAGAAACTAGTGTAA

Protein

MELIKLSSLLVIALLADCASALYFHIAEGERKCFIEEIPDDTTVIVNYKVELYDPKSGGFMQTTPGIGMHVEVRDPNDRILLSRVYSLEGMISFTSSTPGEHVICMYSNSTSWFSGSQLRVHLDIQVGEHAVDYANVAQKEKLTELQLRIRQLLDQVHQITKEQAYQRQREERFRQTSESTNQRVLWWSLLQTGVLVIIGYWQMRHLKSFFEAKKLV

Description

Eca and bai are essential, though not redundant, for dorsoventral patterning of the embryo. Specifically required during early embryogenesis for the activity of maternal tkv, while the zygotic tkv is not affected. Involved in Golgi organization (By similarity).
Eca and bai are essential, though not redundant, for dorsoventral patterning of the embryo. Specifically required during early embryogenesis for the activity of maternal tkv, while the zygotic tkv is not affected. Involved in Golgi organization.
Eca and bai are essential, though not redundant, for dorsoventral patterning of the embryo. Specifically required during early embryogenesis for the activity of maternal tkv, while the zygotic tkv is not affected (By similarity).

Similarity

Belongs to the EMP24/GP25L family.

Keywords

Coiled coil   Complete proteome   Developmental protein   Endoplasmic reticulum   Membrane   Reference proteome   Signal   Transmembrane   Transmembrane helix  

Feature

chain  Transmembrane emp24 domain-containing protein eca

Uniprot

H9JN56   Q1HPQ2   A0A2A4JCN9   A0A2W1BZP9   A0A2H1WXB8   A0A0N1INF2   + More
I4DJD2   A0A1E1WGL2   S4PH18   A0A3S2MAV2   A0A023EJU6   Q17PC5   A0A1B0CIA4   B0WIW6   A0A1J1HQS7   T1PFU6   A0A1Q3FFE8   A0A1I8Q7K9   A0A1L8DUK7   A0A182PH49   A0A1L8EH76   A0A182R1B3   A0A023EJW6   A0A232EF15   T1DNY4   A0A2M3ZE05   A0A182S6W0   A0A182VS02   K7IXG7   W5JU51   A0A1W4VMP4   A0A2M4BZ91   B4NKL0   A0A2P8YKL6   A0A182MA66   A0A0C9R9A1   A0A1A9WRT1   B3NZM5   B6DE49   A0A182Y7F4   A0A182HZ86   Q5TT51   B4PVC6   A0A067QZG4   A0A182KXF5   B4JG34   A0A0L7LI10   A0A1D2N005   B4QWH9   A0A1A9X6H8   B4HJV5   A0A1A9ZCD7   U5EYW2   A0A0M5J4J5   A0A0K8VH47   A0A084VB09   A0A034WPT5   A0A1A9UIH2   D3TQM6   A0A1L8E9Y5   A0A3B0K2L6   B4GMC3   Q295B2   Q9I7K5   V5G3R8   B4KB41   A0A0L0BYF5   D6WAK8   A0A182J1V2   W8C7B1   A0A2M4A701   B3MTS8   B4LYB8   F4WRB6   A0A087TYQ0   A0A151IS72   A0A195BBI1   A0A158NUP9   A0A151WRB9   A0A151IG88   A0A1W4X6D8   E2A3C1   E2C7M8   A0A026WUH1   A0A154PNP2   A0A1W7RAK0   A0A0L7QVL3   A0A162PC44   A0A336MSZ2   A0A1B6GFM4   A0A336MNP2   A0A0P5NWG3   A0A0P5PJC8   E9G297   A0A0J7K846   A0A0P6FRH2   A0A0P5PMZ4   A0A0P6H799   A0A182WVV2   A0A182V8W3  

Pubmed

19121390    28756777    26354079    22651552    23622113    24945155    + More
26483478    17510324    25315136    28648823    20075255    20920257    23761445    17994087    29403074    19178717    25244985    12364791    14747013    17210077    24845553    20966253    26227816    27289101    24438588    25348373    20353571    15632085    10731132    12537572    12537569    15327786    21383842    26108605    18362917    19820115    24495485    21719571    21347285    20798317    24508170    21292972   

EMBL

BABH01033318    DQ443350    ABF51439.1    NWSH01002102    PCG69192.1    KZ149909    + More
PZC78196.1    ODYU01011769    SOQ57701.1    KQ461153    KPJ08642.1    AK401400    KQ459595    BAM18022.1    KPI95865.1    GDQN01004935    JAT86119.1    GAIX01005965    JAA86595.1    RSAL01000002    RVE55005.1    RVE55058.1    JXUM01002517    GAPW01004242    KQ560140    JAC09356.1    KXJ84212.1    CH477193    EAT48506.1    AJWK01013122    DS231953    EDS28792.1    CVRI01000018    CRK90323.1    KA647544    AFP62173.1    GFDL01008774    JAV26271.1    GFDF01003965    JAV10119.1    GFDG01000758    JAV18041.1    AXCN02000233    GAPW01004243    JAC09355.1    NNAY01005198    OXU16902.1    GAMD01002455    JAA99135.1    GGFM01005991    MBW26742.1    AAZX01005305    ADMH02000081    ETN67877.1    GGFJ01009256    MBW58397.1    CH964272    EDW85182.1    PYGN01000528    PSN44795.1    AXCM01001479    GBYB01012969    JAG82736.1    CH954181    EDV49735.1    EU934418    ACI30196.1    APCN01005504    AAAB01008888    EAL40586.3    CM000160    EDW96699.1    KK852811    KDR15945.1    CH916369    EDV93601.1    JTDY01001053    KOB75004.1    LJIJ01000339    ODM98627.1    CM000364    EDX13583.1    CH480815    EDW42839.1    GANO01001778    JAB58093.1    CP012526    ALC45711.1    GDHF01014121    JAI38193.1    ATLV01004843    KE524243    KFB35153.1    GAKP01003205    GAKP01003204    JAC55748.1    CCAG010020272    EZ423728    ADD20004.1    GFDG01003261    JAV15538.1    OUUW01000014    SPP88474.1    CH479185    EDW37997.1    CM000070    EAL28800.1    AE014297    AY051693    AAG22137.2    AAK93117.1    GALX01003796    JAB64670.1    CH933806    EDW15745.1    JRES01001243    KNC24304.1    KQ971312    EEZ97984.1    GAMC01003709    JAC02847.1    GGFK01003189    MBW36510.1    CH902623    EDV30209.1    CH940650    EDW66914.1    GL888284    EGI63333.1    KK117351    KFM70239.1    KQ981085    KYN09588.1    KQ976532    KYM81582.1    ADTU01026661    KQ982806    KYQ50449.1    KQ977739    KYN00236.1    GL436364    EFN72065.1    GL453386    EFN76055.1    KK107109    EZA59321.1    KQ434980    KZC13084.1    GFAH01000209    JAV48180.1    KQ414726    KOC62655.1    LRGB01000512    KZS18720.1    UFQS01002486    UFQT01002486    SSX14146.1    SSX33562.1    GECZ01008517    JAS61252.1    UFQS01001753    UFQT01001753    SSX12218.1    SSX31670.1    GDIQ01141198    JAL10528.1    GDIQ01127553    JAL24173.1    GL732530    EFX86206.1    LBMM01012043    KMQ86454.1    GDIQ01043986    JAN50751.1    GDIQ01147097    JAL04629.1    GDIQ01033384    JAN61353.1   

Proteomes

UP000005204    UP000218220    UP000053240    UP000053268    UP000283053    UP000069940    + More
UP000249989    UP000008820    UP000092461    UP000002320    UP000183832    UP000095301    UP000095300    UP000075885    UP000075886    UP000215335    UP000075901    UP000075920    UP000002358    UP000000673    UP000192221    UP000007798    UP000245037    UP000075883    UP000091820    UP000008711    UP000076408    UP000075840    UP000007062    UP000002282    UP000027135    UP000075882    UP000001070    UP000037510    UP000094527    UP000000304    UP000092443    UP000001292    UP000092445    UP000092553    UP000030765    UP000078200    UP000092444    UP000268350    UP000008744    UP000001819    UP000000803    UP000009192    UP000037069    UP000007266    UP000075880    UP000007801    UP000008792    UP000007755    UP000054359    UP000078492    UP000078540    UP000005205    UP000075809    UP000078542    UP000192223    UP000000311    UP000008237    UP000053097    UP000076502    UP000053825    UP000076858    UP000000305    UP000036403    UP000076407    UP000075903   

PRIDE

H9JN56    Q1HPQ2    B4NKL0    B3NZM5    B4PVC6    B4QWH9    + More
B4HJV5    B4GMC3    Q295B2    Q9I7K5    B4KB41    B3MTS8    B4LYB8   

Pfam

PF01105   EMP24_GP25L        + More
PF00856   SET

Interpro

IPR015720   TMP21-related        + More
IPR009038   GOLD_dom       
IPR001214   SET_dom       

ProteinModelPortal

H9JN56   Q1HPQ2   A0A2A4JCN9   A0A2W1BZP9   A0A2H1WXB8   A0A0N1INF2   + More
I4DJD2   A0A1E1WGL2   S4PH18   A0A3S2MAV2   A0A023EJU6   Q17PC5   A0A1B0CIA4   B0WIW6   A0A1J1HQS7   T1PFU6   A0A1Q3FFE8   A0A1I8Q7K9   A0A1L8DUK7   A0A182PH49   A0A1L8EH76   A0A182R1B3   A0A023EJW6   A0A232EF15   T1DNY4   A0A2M3ZE05   A0A182S6W0   A0A182VS02   K7IXG7   W5JU51   A0A1W4VMP4   A0A2M4BZ91   B4NKL0   A0A2P8YKL6   A0A182MA66   A0A0C9R9A1   A0A1A9WRT1   B3NZM5   B6DE49   A0A182Y7F4   A0A182HZ86   Q5TT51   B4PVC6   A0A067QZG4   A0A182KXF5   B4JG34   A0A0L7LI10   A0A1D2N005   B4QWH9   A0A1A9X6H8   B4HJV5   A0A1A9ZCD7   U5EYW2   A0A0M5J4J5   A0A0K8VH47   A0A084VB09   A0A034WPT5   A0A1A9UIH2   D3TQM6   A0A1L8E9Y5   A0A3B0K2L6   B4GMC3   Q295B2   Q9I7K5   V5G3R8   B4KB41   A0A0L0BYF5   D6WAK8   A0A182J1V2   W8C7B1   A0A2M4A701   B3MTS8   B4LYB8   F4WRB6   A0A087TYQ0   A0A151IS72   A0A195BBI1   A0A158NUP9   A0A151WRB9   A0A151IG88   A0A1W4X6D8   E2A3C1   E2C7M8   A0A026WUH1   A0A154PNP2   A0A1W7RAK0   A0A0L7QVL3   A0A162PC44   A0A336MSZ2   A0A1B6GFM4   A0A336MNP2   A0A0P5NWG3   A0A0P5PJC8   E9G297   A0A0J7K846   A0A0P6FRH2   A0A0P5PMZ4   A0A0P6H799   A0A182WVV2   A0A182V8W3  

PDB

5AZY     E-value=0.0100215,     Score=88

KEGG

733126    K20346 p24 family protein alpha | (RefSeq) transmembrane emp24 protein transport domain containing 9

GO

GO:0016021   GO:0005789   GO:0009953   GO:0005783   GO:0005793   GO:0006886   GO:0006888   GO:0005794   GO:0030134   GO:0007030   GO:0034389   GO:0035220   GO:0061355   GO:0012505   GO:0048193   GO:0005215   GO:0048042   GO:0006810   GO:0006520   GO:0006508   GO:0008237   GO:0008152   GO:0016787   GO:0003676   GO:0016491   GO:0015930  

PANTHER

PTHR22811  

Subcellular location

Endoplasmic reticulum membrane  
Membrane  

SignalP

Position:   1 - 21,         Likelihood:  0.992858

 

 

Length:

217

Number of predicted TMHs:

2

Exp number of AAs in TMHs:

33.58055

Exp number, first 60 AAs:

15.37117

Total prob of N-in:

0.19859

POSSIBLE N-term signal

sequence

outside

1  -  3

TMhelix

4  -  26

inside

27  -  184

TMhelix

185  -  204

outside

205  -  217

 

 

Pi

22.235753

Theta

20.745217

Tajima's D

0.021586

CLR

303.081814

CSRT

0.382780860956952

Interpretation

Uncertain