Gene

KWMTBOMO13594

Pre Gene Modal

BGIBMGA010960

Annotation

PREDICTED:_glutamate_receptor_ionotropic?_delta-2-like_[Bombyx_mori]

Location

Bomo_Chr23(-):2471905-2474363      View in EpiBrowser

Full name

Ionotropic receptor 93a      

Location in the cell

Cytoplasmic   Reliability : 2.411

CDS

ATGAGTGCTTTTATATCGGCACTGGACGCTGCAATACAAGCCGAGTTCGATGTGGCTGCTCAAGTCTCAGATGAAGAGTGGGAAGCGATCAGACCCAGCAAAGTACAACGGAGGGACATCCTACTTAAGCACATGCAGCAATACATATTGGCGAAAAGTGTCTGTGGAAACTGCACATTGTGGCGAGCATTAGCGGCCGATACTTGGGGCGTTACGTACCGGCAAAATGATGTACCTGAACAAATTAATGAACATGCGAATGGTTCTACCGGAGTTATTGAGCATCTTGAATTAATGAATGTCGGAATTTGGCGTCCAATCGACGCTATGACGTTTGCGGATTTATTATTTCCTCACGTGCATCACGGGTTTAGAGGGAAAGAATTACCGATAATAACTTATCATAATCCTCCGTGGACGTTCCTACAAGCAAACGAATCGGGCGCCATCGTGAAATACAGTGGACTTATGTTTGATATCGTCAATCAATTGGCTAAGAACAAAAACTTTACGTGA

Protein

MSAFISALDAAIQAEFDVAAQVSDEEWEAIRPSKVQRRDILLKHMQQYILAKSVCGNCTLWRALAADTWGVTYRQNDVPEQINEHANGSTGVIEHLELMNVGIWRPIDAMTFADLLFPHVHHGFRGKELPIITYHNPPWTFLQANESGAIVKYSGLMFDIVNQLAKNKNFT

Description

Integral part of various neural sensory systems in the antenna that provide the neural basis for the response to environmental changes in temperature (thermosensation) and humidity (hygrosensation) (PubMed:27161501, PubMed:27656904). Together with Ir21a and Ir25a, mediates the response of the larval dorsal organ cool cells, a trio of cool-responsive neurons, to cooling and is required for cool avoidance behavior (PubMed:27656904, PubMed:27161501). Together with Ir25a and Ir40a, mediates the response of the hydrosensory sacculus neurons to changes in relative humidity, and is required for dry detection and humidiy preference behavior (PubMed:27656904, PubMed:27161501).

Similarity

Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family.
Belongs to the serpin family.

Keywords

Behavior   Cell membrane   Complete proteome   Glycoprotein   Ion channel   Ion transport   Ligand-gated ion channel   Membrane   Receptor   Reference proteome   Sensory transduction   Signal   Transmembrane   Transmembrane helix   Transport  

Feature

chain  Ionotropic receptor 93a

Uniprot

H9JN57   A0A1V1WBR8   A0A075T315   A0A1B3B712   A0A2A4JB37   A0A2W1BX10   + More
A0A140G9H9   A0A223HCX8   A0A2K8GL64   A0A0F7QED6   A0A0U3AN12   A0A0N0PAW0   A0A0K8TUZ0   H9A5R3   A0A1Q1PP67   A0A223HDA3   A0A3Q8HE93   A0A345BF18   A0A212EVP0   A0A0N1I3G6   A0A2H1WR76   A0A194PQY9   A0A0X7YRY0   A0A2H4ZBD8   A0A2P9JY97   A0A2P9JY96   D6WAL7   A0A1W4X7K5   A0A1B0CLF6   A0A182NSU9   A0A182S992   A0A1J1J4N3   A0A182MEF6   A0A182YCU4   A0A084VLQ9   A0A182XC00   B0WQA0   A0A182FK55   A0A182W5R3   A0A182QEU3   A0A182RHP7   E0VYD3   A0A182V701   A0A182KWB8   A0A182UKG1   Q7QF16   A0A182H717   A0A182IAI4   A0A182PT67   A0A182IKJ8   A0A1W7R6R4   Q17BD0   A0A336KK94   A0A336MCA1   A0A067QZS4   A0A2R7WKJ9   A0A182KC39   T1HWR6   A0A336M6C6   A0A2P8Y258   N6UCM3   J9LL06   A0A2S2NZZ6   A0A1I8M4L7   B4K8X5   A0A1W6L1D8   A0A2I4PH72   A0A3L9LWH3   B4NFS0   A0A1A9X5X6   A0A154PHZ8   A0A158P159   A0A195AU31   B4JUF3   B4LWJ3   F4WUV8   Q9VDH6   A0A348AZZ9   A0A0L0C0C3   W8C668   B4II62   W8BGJ6   B4R1Q8   A0A151WW03   A0A1A9W573   A0A0K8UUG0   B4PPU0   A0A087ZTI4   A0A2A3EJL2   A0A1W4UXM9   A0A1I8PK70   B3P315   A0A1B0FK80   A0A088AGB3   A0A3B0K0B0   I5ANT4   K7INR5   A0A195CZ29   E2A2H5   A0A0N0BK77  

Pubmed

19121390    25027790    28756777    27004525    28150741    29375398    + More
25803580    26657286    26354079    26017144    22363688    27006164    29727827    22118469    29133804    18362917    19820115    25244985    24438588    20566863    20966253    12364791    14747013    17210077    26483478    17510324    24845553    29403074    23537049    25315136    17994087    21347285    21719571    10731132    12537572    12537569    27161501    27656904    30026095    26108605    24495485    17550304    15632085    20075255    20798317   

EMBL

BABH01033313    BABH01033314    BABH01033315    BABH01033316    BABH01033317    GENK01000120    + More
JAV45793.1    KF768729    AIG51923.1    KT588090    AOE48000.1    NWSH01002102    PCG69181.1    KZ149909    PZC78164.1    KU702631    AMM70658.1    KY283579    AST36239.1    KY225530    ARO70542.1    LC017797    BAR64811.1    KP975113    ALT31632.1    KQ461153    KPJ08640.1    GCVX01000144    JAI18086.1    JN836713    AFC91753.2    KY325459    AQM73620.1    KY283708    AST36367.1    MF625615    AXY83442.1    MG820671    AXF48842.1    AGBW02012158    OWR45556.1    KQ459132    KPJ03769.1    ODYU01010446    SOQ55563.1    KQ459595    KPI95866.1    KJ186796    AIX97108.1    MF975495    AUF73071.1    KY817087    AVH87303.1    KY817086    AVH87302.1    KQ971312    EEZ97979.1    AJWK01017210    AJWK01017211    CVRI01000070    CRL07373.1    AXCM01000631    ATLV01014545    KE524974    KFB38903.1    DS232037    EDS32763.1    AXCN02002230    DS235845    EEB18389.1    AAAB01008846    EAA06694.5    JXUM01115368    KQ565873    KXJ70579.1    APCN01001254    GEHC01000807    JAV46838.1    CH477323    EAT43564.1    UFQS01000374    UFQT01000374    SSX03303.1    SSX23669.1    SSX03302.1    SSX23668.1    KK852811    KDR15941.1    KK854966    PTY19999.1    ACPB03021581    UFQT01000596    SSX25580.1    PYGN01001027    PSN38342.1    APGK01028705    KB740695    KB631593    ENN79415.1    ERL84516.1    ABLF02021911    GGMR01010174    MBY22793.1    CH933806    EDW16572.2    KX609442    ARN17849.1    KU523586    APZ81408.1    KB466082    RLZ02220.1    CH964251    EDW83137.2    KQ434902    KZC11114.1    ADTU01005793    ADTU01005794    ADTU01005795    KQ976738    KYM75686.1    CH916374    EDV91123.1    CH940650    EDW67658.2    GL888378    EGI62022.1    AE014297    AY069028    BT001372    AAL39173.1    AAN71127.1    FX985990    BBD43525.1    JRES01001168    KNC24884.1    GAMC01008686    JAB97869.1    CH480842    EDW49606.1    GAMC01008688    JAB97867.1    CM000364    EDX12167.1    KQ982691    KYQ52082.1    GDHF01022151    JAI30163.1    CM000160    EDW96190.2    KZ288235    PBC31389.1    CH954181    EDV48329.1    CCAG010014365    OUUW01000013    SPP87745.1    CM000070    EIM52619.2    KQ977141    KYN05389.1    GL436038    EFN72378.1    KQ435706    KOX80204.1   

Proteomes

UP000005204    UP000218220    UP000053240    UP000007151    UP000053268    UP000007266    + More
UP000192223    UP000092461    UP000075884    UP000075901    UP000183832    UP000075883    UP000076408    UP000030765    UP000076407    UP000002320    UP000069272    UP000075920    UP000075886    UP000075900    UP000009046    UP000075903    UP000075882    UP000075902    UP000007062    UP000069940    UP000249989    UP000075840    UP000075885    UP000075880    UP000008820    UP000027135    UP000075881    UP000015103    UP000245037    UP000019118    UP000030742    UP000007819    UP000095301    UP000009192    UP000007798    UP000092443    UP000076502    UP000005205    UP000078540    UP000001070    UP000008792    UP000007755    UP000000803    UP000037069    UP000001292    UP000000304    UP000075809    UP000091820    UP000002282    UP000005203    UP000242457    UP000192221    UP000095300    UP000008711    UP000092444    UP000268350    UP000001819    UP000002358    UP000078542    UP000000311    UP000053105   

PRIDE

H9JN57    Q9VDH6   

Pfam

PF00060   Lig_chan        + More
PF10613   Lig_chan-Glu_bd
PF00497   SBP_bac_3
PF01762   Galactosyl_T
PF00079   Serpin
PF01094   ANF_receptor

Interpro

IPR001320   Iontro_rcpt        + More
IPR001508   Iono_rcpt_met       
IPR019594   Glu/Gly-bd       
IPR001638   Solute-binding_3/MltF_N       
IPR002659   Glyco_trans_31       
IPR036186   Serpin_sf       
IPR042178   Serpin_sf_1       
IPR042185   Serpin_sf_2       
IPR023796   Serpin_dom       
IPR028082   Peripla_BP_I       
IPR001828   ANF_lig-bd_rcpt       

SUPFAM

SSF56574   SSF56574        + More
SSF53822   SSF53822       

Gene 3D

2.30.39.10     3.30.497.10    

ProteinModelPortal

H9JN57   A0A1V1WBR8   A0A075T315   A0A1B3B712   A0A2A4JB37   A0A2W1BX10   + More
A0A140G9H9   A0A223HCX8   A0A2K8GL64   A0A0F7QED6   A0A0U3AN12   A0A0N0PAW0   A0A0K8TUZ0   H9A5R3   A0A1Q1PP67   A0A223HDA3   A0A3Q8HE93   A0A345BF18   A0A212EVP0   A0A0N1I3G6   A0A2H1WR76   A0A194PQY9   A0A0X7YRY0   A0A2H4ZBD8   A0A2P9JY97   A0A2P9JY96   D6WAL7   A0A1W4X7K5   A0A1B0CLF6   A0A182NSU9   A0A182S992   A0A1J1J4N3   A0A182MEF6   A0A182YCU4   A0A084VLQ9   A0A182XC00   B0WQA0   A0A182FK55   A0A182W5R3   A0A182QEU3   A0A182RHP7   E0VYD3   A0A182V701   A0A182KWB8   A0A182UKG1   Q7QF16   A0A182H717   A0A182IAI4   A0A182PT67   A0A182IKJ8   A0A1W7R6R4   Q17BD0   A0A336KK94   A0A336MCA1   A0A067QZS4   A0A2R7WKJ9   A0A182KC39   T1HWR6   A0A336M6C6   A0A2P8Y258   N6UCM3   J9LL06   A0A2S2NZZ6   A0A1I8M4L7   B4K8X5   A0A1W6L1D8   A0A2I4PH72   A0A3L9LWH3   B4NFS0   A0A1A9X5X6   A0A154PHZ8   A0A158P159   A0A195AU31   B4JUF3   B4LWJ3   F4WUV8   Q9VDH6   A0A348AZZ9   A0A0L0C0C3   W8C668   B4II62   W8BGJ6   B4R1Q8   A0A151WW03   A0A1A9W573   A0A0K8UUG0   B4PPU0   A0A087ZTI4   A0A2A3EJL2   A0A1W4UXM9   A0A1I8PK70   B3P315   A0A1B0FK80   A0A088AGB3   A0A3B0K0B0   I5ANT4   K7INR5   A0A195CZ29   E2A2H5   A0A0N0BK77  

KEGG

101746044    K05313 glutamate receptor, ionotropic, invertebrate | (RefSeq) glutamate receptor ionotropic, delta-

GO

GO:0004970   GO:0016021   GO:0016020   GO:0005886   GO:0045211   GO:0035249   GO:0050804   GO:1904315   GO:0008066   GO:0008378   GO:0006486   GO:0050907   GO:0005615   GO:0007610   GO:0015276   GO:0030054  

Subcellular location

Cell membrane  
  

Length:

171

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.03642

Exp number, first 60 AAs:

0.01892

Total prob of N-in:

0.05509

outside

1  -  171

 

 

Pi

224.999017

Theta

170.548116

Tajima's D

0.978695

CLR

2.930063

CSRT

0.659967001649918

Interpretation

Uncertain