Gene

KWMTBOMO13571

Pre Gene Modal

BGIBMGA010995

Annotation

PREDICTED:_muscarinic_acetylcholine_receptor_DM1_[Bombyx_mori]

Location

Bomo_Chr23(+):1756946-1783596      View in EpiBrowser

Location in the cell

PlasmaMembrane   Reliability : 4.01

CDS

ATGCTGATCGTGTCCAACAACACTGGCAACCTCACCGACCCGGAGCTCGGCCTCGACCTGCCGACCAGCCCCTTCAGCCTCGCCCAGAAGATTGTCATAGCCATCATAGCCAGCGTCCTCTCCGTGCTCACCGTCGTCGGGAACTCCATGGTCATGATCAGTTTCAAGATCGACAAGCAGCTCCAGACCATCAGCAACTACTTCCTGTTTTCTTTGGCGGTGGCCGACTTCGCAGTCGGGCTGATCTCCATGCCCCTGTACACGATGTTCACGATCTACGGATACTGGCCGCTGGGCCCTCATGTGTGCGACACGTGGCTCGCGCTCGACTATCTCGCATCTAACGCGTCCGTTCTGAACCTACTGATCATTAGCTTCGATCGGTACTTCAGCGTGACGCGTCCGCTGACGTACAGGGCGAAAAGGACTACGCGCAGAGCAACCGTGATGATAGGCAGTGCTTGGGGCTTCAGCTTGGTGCTGTGGCCTCCGTGGATATACGCGTGGCCATACATTGACGGCGAGCGGAAGGTGCCTCCGCACGAGTGCTACATTCAGTTCATAGAGACGAACCAATTTATAACATTCGGGACGGCTATTGCCGCGTTTTATGTGCCGGTGACAGTGATGTGTATACTGTACTACAGAATATGGAGGGAGACCAAGAAACGACAGAAGGACCTGCCCAATCTACAGGGCGGGAAGAAACATGACTCGTCGAAAAGATCGAATTCTAGTGACGAAACAAAAGATGCCGACGGACGAGCCCGTTCAGAATCCGGAGACACCGATTCAGTTTATCACGTACGAGGAGTTCTACACGACCACCGATGGAGAGAATCTAAGCCTTCCTGTGCTCGTCCACCGAAACGAGGGTGGGCGGTGGTGCGAGCGTGGTGCGTGGCCTGGTGGCATTCCGGAAGGGAAGACACAGAAGATACGGAGCCAGAGGAGGAACCATCAGACCCTGGCTACGCGACACCGGTTTCTGTAGAAACCCCTCTACAGAGCTCAGTTTCGAGGTGCACGTCGCTTAATGTCATAAGAGATCCATACGCTACACGCGGTGGCTCGAGTGGCTCAGGAGATGGGGGCACATCCCCACTTCGTCGGACCTACGAACCCCCAGGGATGGTCACTTCGGCCAGGGACAGCAGATCTCTACCTCCGAACACACGAATTAACACAACTACCTCACCAGCGCCAAAGTCTGCTTCGGCCGACTCAGTTTACACCATCGTCATCAGGCTACCGGACGCCGATACGGAAAGAGCGACAATTAAAATGATCACCGAAGAGTCGCCTCCGTCTATGGCTAGACCTCACTACCGGCCCACGAGAGGAGACTCCGAGCTAAACTTACATCCGGCCGGCCACGCGGCGCTGACGCGACGAACTTCACACATACAGGACGTTCGAATACCGCTCAACGCCAAAATCATACCTAAACAATTGGCTGGCAAAGGCTTGACTAAGCAGCCAAAGAAAAAGAAGACGCAGGAAAAGAAACAGGAGACGAAAGCAGCCAAGACCCTCTCAGCCATCCTGCTGTCGTTCATCATAACGTGGACCCCATACAACATCTTGGTGTTGCTGAAGCCTCTGACGGCTTGCACGAAATGCATTCCGGCCGAGTTGTGGTCGTTTTTCTACGCTCTCTGTTATATCAATTCGACTATAAACCCGGTGTGCTACGCGCTGTGCAACGCCACCTTCCGGAGGACGTACGTCAGGATCCTGACGTGCAAGTGGCACAACCGGAACCGGGAGGCGATGACTCGTGGGGTTTACAATTAG

Protein

MLIVSNNTGNLTDPELGLDLPTSPFSLAQKIVIAIIASVLSVLTVVGNSMVMISFKIDKQLQTISNYFLFSLAVADFAVGLISMPLYTMFTIYGYWPLGPHVCDTWLALDYLASNASVLNLLIISFDRYFSVTRPLTYRAKRTTRRATVMIGSAWGFSLVLWPPWIYAWPYIDGERKVPPHECYIQFIETNQFITFGTAIAAFYVPVTVMCILYYRIWRETKKRQKDLPNLQGGKKHDSSKRSNSSDETKDADGRARSESGDTDSVYHVRGVLHDHRWRESKPSCARPPKRGWAVVRAWCVAWWHSGREDTEDTEPEEEPSDPGYATPVSVETPLQSSVSRCTSLNVIRDPYATRGGSSGSGDGGTSPLRRTYEPPGMVTSARDSRSLPPNTRINTTTSPAPKSASADSVYTIVIRLPDADTERATIKMITEESPPSMARPHYRPTRGDSELNLHPAGHAALTRRTSHIQDVRIPLNAKIIPKQLAGKGLTKQPKKKKTQEKKQETKAAKTLSAILLSFIITWTPYNILVLLKPLTACTKCIPAELWSFFYALCYINSTINPVCYALCNATFRRTYVRILTCKWHNRNREAMTRGVYN

Similarity

Belongs to the G-protein coupled receptor 1 family.

Uniprot

A0A2D1QUJ3   A0A2W1BSZ2   A0A2A4J5F8   A0A336MEG8   A0A336M9L5   J9HZX1   + More
A0A084WAY1   D6WCK6   M9PPU6   N1NTZ8   A0A140WM08   W5JB91   A0A1W4WA99   Q7Q8W8   A0A1J1IM64   W8CAB3   A0A1B0ARN6   A0A1A9YJL8   A0A1A9WQE5   A0A1A9UWA7   A0A1A9ZRA2   C1IHD3   E0VWJ3   A0A1S4MUW4   A0A088AJH6   V9I8U2   A0A2A3E6S6   A0A0M8ZPH7   A0A3L8DAX9   A0A026X278   A0A0J7L6E9   E1ZZZ3   K7IUJ0   E9IWZ5   A0A3Q0IXA6   A0A158NKG7   A0A195EHF1   A0A1L4BJY2   A0A151WTB6   U4UST1   T1J5S4   H9B3Y4   N6UF70   A0A151IK00   A0A195FAV9   B7P8V1   A0A1D2N1D3   A0A154PMV3   E2B302   A0A0C9S084   A0A2H8U013   A0A2P6KK74   J9JXP0   A0A2S2Q6L2  

Pubmed

28756777    17510324    24438588    18362917    19820115    23604020    + More
18054377    18025266    18316733    20068045    21843505    20920257    23761445    12364791    14747013    17210077    24495485    21678488    20566863    30249741    24508170    20798317    20075255    21282665    21347285    23537049    22403662    27289101   

EMBL

KY296116    ATP16187.1    KZ149909    PZC78178.1    NWSH01003084    PCG66976.1    + More
UFQS01000782    UFQT01000782    SSX06848.1    SSX27193.1    UFQT01000758    SSX27032.1    CH478019    EJY58035.1    ATLV01022281    ATLV01022282    KE525331    KFB47375.1    KQ971311    EEZ99326.2    JX174094    AGG09676.1    BK005871    DAA64508.1    JQ922422    AFJ23966.1    ADMH02002000    ETN60034.1    AAAB01008933    EAA09886.1    CVRI01000051    CRK99561.1    GAMC01005911    JAC00645.1    JXJN01002497    EU573239    ACE60222.1    DS235822    EEB17749.1    AAZO01005903    AAZO01005904    AAZO01005905    AAZO01005906    AAZO01005907    JR036975    JR036976    AEY57510.1    AEY57511.1    KZ288349    PBC27415.1    KQ436240    KOX67346.1    QOIP01000011    RLU17078.1    KK107021    EZA62397.1    LBMM01000528    KMQ98133.1    GL435531    EFN73233.1    AAZX01002654    GL766616    EFZ14907.1    ADTU01018834    ADTU01018835    KQ978881    KYN27700.1    KX021833    API81623.1    KQ982762    KYQ51073.1    KB632350    ERL93236.1    JH431868    JN974913    AFC88982.1    APGK01024521    APGK01024522    APGK01024523    APGK01024524    APGK01024525    APGK01024526    APGK01024527    APGK01024528    KB740549    ENN80390.1    KQ977294    KYN03953.1    KQ981693    KYN37755.1    ABJB010517326    DS660344    EEC03023.1    LJIJ01000304    ODM99021.1    KQ434996    KZC13215.1    GL445250    EFN89971.1    GBYB01013901    JAG83668.1    GFXV01008078    MBW19883.1    MWRG01010074    PRD26735.1    ABLF02029590    ABLF02029591    GGMS01004103    GGMS01004180    MBY73306.1    MBY73383.1   

Proteomes

UP000218220    UP000008820    UP000030765    UP000007266    UP000000673    UP000192223    + More
UP000007062    UP000183832    UP000092460    UP000092443    UP000091820    UP000078200    UP000092445    UP000009046    UP000005203    UP000242457    UP000053105    UP000279307    UP000053097    UP000036403    UP000000311    UP000002358    UP000079169    UP000005205    UP000078492    UP000075809    UP000030742    UP000019118    UP000078542    UP000078541    UP000001555    UP000094527    UP000076502    UP000008237    UP000007819   

Pfam

PF00001   7tm_1        + More
PF08327   AHSA1
PF09229   Aha1_N

Interpro

IPR017452   GPCR_Rhodpsn_7TM        + More
IPR000276   GPCR_Rhodpsn       
IPR000995   Musac_Ach_rcpt       
IPR015310   AHSA1_N       
IPR036338   Aha1       
IPR023393   START-like_dom_sf       
IPR013538   Activator_of_Hsp90_ATPase       

SUPFAM

SSF103111   SSF103111       

Gene 3D

3.15.10.20     3.30.530.20    

ProteinModelPortal

A0A2D1QUJ3   A0A2W1BSZ2   A0A2A4J5F8   A0A336MEG8   A0A336M9L5   J9HZX1   + More
A0A084WAY1   D6WCK6   M9PPU6   N1NTZ8   A0A140WM08   W5JB91   A0A1W4WA99   Q7Q8W8   A0A1J1IM64   W8CAB3   A0A1B0ARN6   A0A1A9YJL8   A0A1A9WQE5   A0A1A9UWA7   A0A1A9ZRA2   C1IHD3   E0VWJ3   A0A1S4MUW4   A0A088AJH6   V9I8U2   A0A2A3E6S6   A0A0M8ZPH7   A0A3L8DAX9   A0A026X278   A0A0J7L6E9   E1ZZZ3   K7IUJ0   E9IWZ5   A0A3Q0IXA6   A0A158NKG7   A0A195EHF1   A0A1L4BJY2   A0A151WTB6   U4UST1   T1J5S4   H9B3Y4   N6UF70   A0A151IK00   A0A195FAV9   B7P8V1   A0A1D2N1D3   A0A154PMV3   E2B302   A0A0C9S084   A0A2H8U013   A0A2P6KK74   J9JXP0   A0A2S2Q6L2  

PDB

5ZK8     E-value=8.69398e-59,     Score=577

KEGG

101745328    K04131 muscarinic acetylcholine receptor M3 | (RefSeq) muscarinic acetylcholine receptor DM1

PATHWAY

04080    Neuroactive ligand-receptor interaction - Bombyx mori (domestic silkworm)

GO

GO:0016907   GO:0005887   GO:0030425   GO:0007197   GO:0004930   GO:0004993   GO:0030594   GO:0007187   GO:0007268   GO:0004715   GO:0016021   GO:0051087   GO:0001671   GO:0007186   GO:0019538   GO:0030145   GO:0003676   GO:0016491   GO:0015930  

Length:

598

Number of predicted TMHs:

7

Exp number of AAs in TMHs:

155.90802

Exp number, first 60 AAs:

22.71127

Total prob of N-in:

0.00106

POSSIBLE N-term signal

sequence

outside

1  -  32

TMhelix

33  -  55

inside

56  -  67

TMhelix

68  -  90

outside

91  -  104

TMhelix

105  -  126

inside

127  -  146

TMhelix

147  -  169

outside

170  -  192

TMhelix

193  -  215

inside

216  -  511

TMhelix

512  -  531

outside

532  -  545

TMhelix

546  -  568

inside

569  -  598

 

 

Pi

288.253247

Theta

209.392865

Tajima's D

1.224572

CLR

0.8144

CSRT

0.720013999300035

Interpretation

Uncertain