Gene

KWMTBOMO13555

Pre Gene Modal

BGIBMGA010987

Annotation

alpha-esterase_45_[Bombyx_mori]

Location

Bomo_Chr23(+):1466243-1470853      View in EpiBrowser

Full name

Carboxylic ester hydrolase      

Location in the cell

Cytoplasmic   Reliability : 3.118

CDS

ATGGTCAAAGTAAAAGTAACGCAAGGCTGGTTGGAAGGCGAGGTGCTGGAGACCGTGACCGGGTATAGAAAGTACTATAGCTTCAAGGGTATTCCATATGCTGAACCTCCCTTAGGAAAACTCAGATTCAAGGCTCCGCGACCAGCGCTGCCCTGGGAGGGAGTCAAAAAAGCAACACAGCATGGACCTGTATGCCCTCAAGTGGACATCTTCACAGAAATCCTGATTCCGGGAAGTGAAGATTGTCTTTATTTAAACGTGTACACGCCCGAAATCAATTCTGAAACGCTCTTACCAGTCATGTTCTTCATCCATGGAGGTGGTTACAAGAGTGGCTCAGGAAATGTTGACAATTATGGACCCGACTTCCTTGTAGCCCACGGAATAGTATTAGTCACGATTAATTACAGACTTGACGCATTAGGATTCCTTTGCTTGGACACTGAAGAAGTGCCAGGAAATGCTGGTATGAAAGACCAAGTAGCTGCTTTAAAGTGGGTTAAAGAGAATATTTCAAGTTTTGGTGGAGATCCAGATAACATTACTGTGTTTGGTGAAAGTGCCGGTGGGGCGTCTACATCTTTCCACGTCATATCGCCGATGTCAAAAGGCTTGTTTAAAAGAGTGATTTCGATGAGCGGGGTCCTATTCTGTGATTGGTCCATAGCATTCGAACCAAGAAGAAGAGCGTTCAAACTTGGACAGCTTTTGGGAATTGAAACCGAGAATCCAGATGAATTACTCGAATATCTACAAAACGTTCCAGTAGAGAAATTAGTCAATACAGATCCTAACATAATAACAATGGAAGAACTACACAAAAATATGCTCAAATTTTATCATTTCACGCCAGTTGTCGAAAAAGATTTTGGTCAAGAACACTTTTTGACACGTGAACCAATTGAAGTCCTTAAACATGGAAATATTAATGATGTAGATATGCTATTAGGTTTCACAAATGAAGAAGCAATAATAGGAATAACGCTTTTAGAGAAACATCTAGTGCATTTGTACAATAAGTACATCGATTTGTTCGCACCTAGGTTGATAACAATTAAGGCGACACCAGATAAAGTCTTAGAAATATCCGACAGAATACGTCATTTTTATTTCGGCAATAAAAAGGTTAATTTAGAATCTATGAGGGAATTTGTCACGTTTGTTAACGACTGTGGATTTATATATCCCATTCACAGATTTGCGGGTAAATTGTCGGATCTAATTAATACGAAAGTTTTCATGTACAAATTTTCGATGTTTTCAAATCGAAATGTGTATGGTGCGGCCGGTGCTAATTACAAGATAACTGGGGCCTCGCATTTGGAAGATTTGATGTATCTGTTTGACGCCAAAAAATTTGACTTGAAGATTGAGACAACGAGCAGGGAATATCGTTTAATTAATCTGGCTTGCACAATTTTTACCAATTTTGCGAAATTTGGTAATCCAACACCGGACACATCTCTGGGAGTGAAGTGGCCAGAATACAATAAAGAGACAAGAAAATACTGCGACATCGGAGATGAGCTCACCATTGGACTGGATAACTACAGACAGACAGTCGACTTCTGGAAAAAAGTATATGAAGATGCCGGTCTAGAATTCTAA

Protein

MVKVKVTQGWLEGEVLETVTGYRKYYSFKGIPYAEPPLGKLRFKAPRPALPWEGVKKATQHGPVCPQVDIFTEILIPGSEDCLYLNVYTPEINSETLLPVMFFIHGGGYKSGSGNVDNYGPDFLVAHGIVLVTINYRLDALGFLCLDTEEVPGNAGMKDQVAALKWVKENISSFGGDPDNITVFGESAGGASTSFHVISPMSKGLFKRVISMSGVLFCDWSIAFEPRRRAFKLGQLLGIETENPDELLEYLQNVPVEKLVNTDPNIITMEELHKNMLKFYHFTPVVEKDFGQEHFLTREPIEVLKHGNINDVDMLLGFTNEEAIIGITLLEKHLVHLYNKYIDLFAPRLITIKATPDKVLEISDRIRHFYFGNKKVNLESMREFVTFVNDCGFIYPIHRFAGKLSDLINTKVFMYKFSMFSNRNVYGAAGANYKITGASHLEDLMYLFDAKKFDLKIETTSREYRLINLACTIFTNFAKFGNPTPDTSLGVKWPEYNKETRKYCDIGDELTIGLDNYRQTVDFWKKVYEDAGLEF

Similarity

Belongs to the type-B carboxylesterase/lipase family.

Feature

chain  Carboxylic ester hydrolase

Uniprot

H9JN84   A9LS22   A0A076FRM1   A0A2A4JFQ0   A0A291P123   A0A2W1BR44   + More
A0A0K8TUL7   A0A0L7KNG8   A0A0K8TVU9   A0A1J0M1C9   D3GDL4   A0A1U9X1T3   A0A2H1VCP7   A0A2S0D881   A0A2W1BKQ4   A0A2U3T8L5   A0A2A4JEW3   A0A0Y0B016   A0A194REM3   A0A2U3T8J6   F1C4B8   A0A2U3T8L4   J7HWI3   A0A0L7KL89   A0A0K0XRL4   A0A3S2MAW7   A0A194QDV9   A0A2W1BKK3   A0A109QN31   A0A3S2TTT0   A0A2U3T8L2   A0A2U3T8L3   A3QR02   A0A1U9X1T8   A0A291P0Q3   A0A1U9X1X0   D5G3F2   A0A2H1VCP1   D2KTU3   A0A1U9X1U2   A0A346TPC2   H9JN73   U5KKB6   A0A0B4RY15   A0A0F7QEB1   F8V329   D3GDM1   A0A0K8TVW5   A0A291P0R0   A0A291P0Y3   A0A2W1BUX0   D5G3F1   D5G3F0   G1C2I6   A0A2H1VCU4   A0A076FT12   D5G3F3   A0A2W1BMW3   A0A0Y0BIG3   Q1W2E3   A0A2A4JIZ5   A0A291P0V0   A0A2W1BSV8   A0A2W1BGL8   A0A291P0X6   A0A0C5C1R4   H9JN83   D5G3F4   A0A194PSZ9   A0A291P112   A0A2W1C223   A0A291P0U0   A0A194RE38   A0A194PYQ2   A0A2A4JJM6   A0A2H1WNK8   A0A2S0D942   A0A1L8D6J3   A0A0K8TV87   A0A194PSE5   A0A2A4K7Y3   A0A2A4JW69   A0A2A4JXU8   A0A0K0XRL5   A0A291P117   A0A2S0D870   A0A0C5C1M2   A0A088QEL8   A0A2H1WFF3   A0A1L8D6M2   A0A2H1X0W5   A0A194RDD6   A0A1J0M180   A0A194PT59   A0A2H1WF19   A0A2I6RJN9   A0A0K8TVA5   A0A291P0V7  

EC Number

3.1.1.-

Pubmed

19121390    24817326    28986331    28756777    26017144    26227816    + More
26778204    26354079    26198868    20005949    20060470    24053512    25803580    23603019   

EMBL

BABH01033219    EU255790    ABX46627.1    KF960778    AII21980.1    NWSH01001642    + More
PCG70596.1    MF687624    ATJ44550.1    KZ150061    PZC74213.1    GCVX01000041    JAI18189.1    JTDY01007971    KOB64827.1    GCVX01000040    JAI18190.1    KU375427    APD13869.1    FJ652446    ACV60230.1    KY021826    AQY62715.1    ODYU01001848    SOQ38619.1    KX015872    ARM65401.1    PZC74214.1    KX015873    ARM65402.1    PCG70597.1    KU215369    AMB19663.1    KQ460313    KPJ16032.1    KX015845    ARM65374.1    HQ199328    ADX30519.1    KX015871    ARM65400.1    JX489387    GEYN01000055    AFQ20792.1    JAV02074.1    JTDY01009253    KOB63826.1    KP938873    AKS40354.1    RSAL01000002    RVE55036.1    RVE55089.1    KQ459144    KPJ03728.1    PZC74215.1    KU215373    AMB19667.1    RVE55035.1    RVE55088.1    KX015869    ARM65398.1    KX015870    ARM65399.1    DQ401086    ABD62772.1    KY021833    AQY62722.1    MF687565    ATJ44491.1    KY021861    AQY62750.1    FJ997316    ADF43481.1    SOQ38618.1    AB299280    BAI66477.1    KY021834    AQY62723.1    MF589742    AXU41412.1    BABH01033215    JX866739    AGS49143.1    KJ023215    AIY69043.1    LC017767    BAR64781.1    JN019808    AEJ18172.1    FJ652453    ACV60237.1    GCVX01000025    JAI18205.1    MF687557    ATJ44483.1    MF687626    ATJ44552.1    KZ149909    PZC78161.1    FJ997315    ADF43480.1    FJ997314    ADF43479.1    JF728805    AEJ38207.1    SOQ38621.1    KF960782    AII21984.1    FJ997317    ADF43482.1    PZC74216.1    KU215366    AMB19660.1    DQ445461    ABE01157.2    NWSH01001228    PCG72037.1    MF687563    ATJ44489.1    PZC78162.1    PZC74212.1    MF687625    ATJ44551.1    KP001159    AJN91204.1    BABH01033216    FJ997318    ADF43483.1    KQ459595    KPI95889.1    MF687632    ATJ44558.1    PZC78163.1    MF687553    ATJ44479.1    KPJ16098.1    KQ459586    KPI98158.1    PCG72029.1    ODYU01009917    SOQ54655.1    KX015867    ARM65396.1    GEYN01000056    JAV02073.1    GCVX01000032    JAI18198.1    KPI95888.1    NWSH01000066    PCG80014.1    NWSH01000459    PCG76251.1    PCG76250.1    KP938878    AKS40359.1    MF687633    ATJ44559.1    KX015852    ARM65381.1    KP001161    AJN91206.1    KM008609    AIN76405.1    ODYU01008252    SOQ51676.1    GEYN01000026    JAV02103.1    ODYU01012558    SOQ58953.1    KQ460323    KPJ15853.1    KU375439    APD13881.1    KPI95949.1    SOQ51678.1    KY304476    AUN86407.1    GCVX01000034    JAI18196.1    MF687564    ATJ44490.1   

Proteomes

UP000005204    UP000218220    UP000037510    UP000053240    UP000283053    UP000053268    + More

PRIDE

H9JN84    A9LS22    D2KTU3    H9JN73    H9JN83   

Pfam

PF00135   COesterase

Interpro

IPR019826   Carboxylesterase_B_AS        + More
IPR019819   Carboxylesterase_B_CS       
IPR029058   AB_hydrolase       
IPR002018   CarbesteraseB       
IPR000997   Cholinesterase       
IPR002168   Lipase_GDXG_HIS_AS       

SUPFAM

SSF53474   SSF53474       

Gene 3D

3.40.50.1820    

ProteinModelPortal

H9JN84   A9LS22   A0A076FRM1   A0A2A4JFQ0   A0A291P123   A0A2W1BR44   + More
A0A0K8TUL7   A0A0L7KNG8   A0A0K8TVU9   A0A1J0M1C9   D3GDL4   A0A1U9X1T3   A0A2H1VCP7   A0A2S0D881   A0A2W1BKQ4   A0A2U3T8L5   A0A2A4JEW3   A0A0Y0B016   A0A194REM3   A0A2U3T8J6   F1C4B8   A0A2U3T8L4   J7HWI3   A0A0L7KL89   A0A0K0XRL4   A0A3S2MAW7   A0A194QDV9   A0A2W1BKK3   A0A109QN31   A0A3S2TTT0   A0A2U3T8L2   A0A2U3T8L3   A3QR02   A0A1U9X1T8   A0A291P0Q3   A0A1U9X1X0   D5G3F2   A0A2H1VCP1   D2KTU3   A0A1U9X1U2   A0A346TPC2   H9JN73   U5KKB6   A0A0B4RY15   A0A0F7QEB1   F8V329   D3GDM1   A0A0K8TVW5   A0A291P0R0   A0A291P0Y3   A0A2W1BUX0   D5G3F1   D5G3F0   G1C2I6   A0A2H1VCU4   A0A076FT12   D5G3F3   A0A2W1BMW3   A0A0Y0BIG3   Q1W2E3   A0A2A4JIZ5   A0A291P0V0   A0A2W1BSV8   A0A2W1BGL8   A0A291P0X6   A0A0C5C1R4   H9JN83   D5G3F4   A0A194PSZ9   A0A291P112   A0A2W1C223   A0A291P0U0   A0A194RE38   A0A194PYQ2   A0A2A4JJM6   A0A2H1WNK8   A0A2S0D942   A0A1L8D6J3   A0A0K8TV87   A0A194PSE5   A0A2A4K7Y3   A0A2A4JW69   A0A2A4JXU8   A0A0K0XRL5   A0A291P117   A0A2S0D870   A0A0C5C1M2   A0A088QEL8   A0A2H1WFF3   A0A1L8D6M2   A0A2H1X0W5   A0A194RDD6   A0A1J0M180   A0A194PT59   A0A2H1WF19   A0A2I6RJN9   A0A0K8TVA5   A0A291P0V7  

PDB

4W1S     E-value=3.291e-84,     Score=796

KEGG

100126869    no KO assigned | (RefSeq) ae45, Bmae45; alpha-esterase 45

GO

GO:0016787   GO:0004104   GO:0016021  

Length:

535

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.25441

Exp number, first 60 AAs:

0.0001

Total prob of N-in:

0.01647

outside

1  -  535

 

 

Pi

214.741674

Theta

185.18225

Tajima's D

0.514537

CLR

213.772491

CSRT

0.515974201289936

Interpretation

Uncertain