Gene

KWMTBOMO13553

Pre Gene Modal

BGIBMGA010976

Annotation

carboxyl/cholinesterase_1_precursor_[Bombyx_mori]

Location

Bomo_Chr23(-):1441690-1445732      View in EpiBrowser

Full name

Carboxylic ester hydrolase      

Location in the cell

PlasmaMembrane   Reliability : 1.145

CDS

ATGTTACTGTTTTATTTAATGTTTGGATTGTTGAGTGGTGTGGAATTGGTGAAAGTTAAAATAACCGAAGGATGGTTGAGAGGTGAATTGTTGGAGGCTTCAACGGGAGACAAGAAATATTACAGTTTCAAAGGAATACCTTATGCGGCGCCACCTCTTGGAAATTTAAGATTTGTGGCTCCTCAACCGCCATTATCCTGGAAAAACGTCAGGGACGCCACACGTCATGGTCCGAAATGCATTCAGACGGAGACTTTGTCGACCAAGTTGGTCCCCGGGAGTGAAGACTGTCTTTTTATCAACGTATACAGTCCAGACCTTAAACCCAAAGAGCAACTACCGGTTATGTTTTTCATATACGGCGGTGGATATAAATCAGGCTCTGGTGATGTCGACGATTATGGACCAGACTTTTTAATAAGATATGACGTAGTCGTCGTGACATTCAACTATAGGCTCGGCGCTTTGGGGTTTTTATGTACAGAAACTAAAGAAGTTCCAGGTAATGCTGGAATGAAAGACCAGGTTGCTGCACTGCGTTGGGTAAAAAGTAACATTGCCCATTTTGGTGGGAACCCAGATCAAGTCACGATTTTTGGACAAAGCGCTGGTGGTGCTTCTGTGGCTTTGCATACTTTGTCTCCCTTATCCAAAGGCTTATTTAAGCGGGCTATTGTAATGAGTGATTCATTCTATAACGACCCATTAAGACCGTTTGAATCTAAAATGAGGGCTTTGGTGTTAGGGAAACGATTGGGCTTAGACACGGCTAATACCACTGAACTTTTGGATTATCTACGGTGTGTGCCCGCTGAAAAGCTATTCATCCAACATCCTAATGTAATAATAACGGAGAGCATCGCTCAAAGTGTTATAAAATTATTCTATTTCACCCCAGTCGTGGAGAAAGATTTCGGTGATGATCATTTTTTGACTGAAGATCCCGAGGTGCTACTCTCTCAAGGTAAAATCCAACAAGACGTCGACTTAATAGTTGGGCACACGAATATAGAAGGTATTTACAATGTGGCTCAGCTTCAGGATAGAGTCCTGAAATATTATCCTTTATACCAGGAACTTTTGGTGCCTCGTAAAATAAGCAACATAAGAGCCCCAACAAAAGTTCTAGAGTTATCTCGTTTGATCTACAGATACTACTTCGGCGACAGACCAATCAATTTGGATACTATCAAAGAATTCGTTTACTACTACACCGACGCGAACTATGCTTATGATGTTTATAGATTTATAAACAAGTTTCCTCAAAGTGCTCACAAGAATCGGTTCTATTACATCTTTTCACCGTATACAGAGAGGAATTATTATTCAAGACTAGGCGCTGAGCGTTATGGCCTATACGGGTCAGCTCATAGAGATGATCTGATGTACTTGTTCGACGGAAAACGATTTAATTTGACTTTAGATAAGAATAGTACGTCGTTCAAGATTATAAATAATTTCTGTGCCTTGTTGACGAACTTCGCTAAATTTGGGAATCCAACACCAGATAATTCTGGAAACGTGATTTGGCCAAAATTTGATAAAGAACAGCGATACCTGAACATTGGAAAAGAGCTTACAGCTAGAAGAATTATGTTTCAGCAGAGTTCTCTTTCATTTTGGAAGAATATTCTAGAGCGAGCCGAACTTGAATTTTAA

Protein

MLLFYLMFGLLSGVELVKVKITEGWLRGELLEASTGDKKYYSFKGIPYAAPPLGNLRFVAPQPPLSWKNVRDATRHGPKCIQTETLSTKLVPGSEDCLFINVYSPDLKPKEQLPVMFFIYGGGYKSGSGDVDDYGPDFLIRYDVVVVTFNYRLGALGFLCTETKEVPGNAGMKDQVAALRWVKSNIAHFGGNPDQVTIFGQSAGGASVALHTLSPLSKGLFKRAIVMSDSFYNDPLRPFESKMRALVLGKRLGLDTANTTELLDYLRCVPAEKLFIQHPNVIITESIAQSVIKLFYFTPVVEKDFGDDHFLTEDPEVLLSQGKIQQDVDLIVGHTNIEGIYNVAQLQDRVLKYYPLYQELLVPRKISNIRAPTKVLELSRLIYRYYFGDRPINLDTIKEFVYYYTDANYAYDVYRFINKFPQSAHKNRFYYIFSPYTERNYYSRLGAERYGLYGSAHRDDLMYLFDGKRFNLTLDKNSTSFKIINNFCALLTNFAKFGNPTPDNSGNVIWPKFDKEQRYLNIGKELTARRIMFQQSSLSFWKNILERAELEF

Similarity

Belongs to the type-B carboxylesterase/lipase family.

Feature

chain  Carboxylic ester hydrolase

Uniprot

D2KTU3   H9JN73   A0A2S0D881   H9JN84   A9LS22   A0A076FRM1   + More
A0A2W1BKQ4   A0A2A4JEW3   A0A2U3T8L5   A0A0K8TUL7   A0A2U3T8J6   A0A2A4JFQ0   A0A0K8TVU9   A0A194REM3   A0A291P123   A0A1U9X1T3   J7HWI3   A0A0L7KNG8   A0A194QDV9   A0A1J0M1C9   A0A2W1BR44   A0A2H1VCP7   F1C4B8   D3GDL4   A0A0K0XRL4   A0A2U3T8L4   A0A3S2MAW7   A0A0Y0B016   A0A2U3T8L2   A0A0L7KL89   A0A109QN31   U5KKB6   D5G3F2   A3QR02   A0A3S2TTT0   A0A2W1BKK3   A0A1U9X1T8   A0A2U3T8L3   A0A2H1WNK8   A0A346TPC2   A0A1U9X1X0   A0A291P0Q3   A0A1U9X1U2   A0A2H1VCP1   A0A0K8TVW5   A0A0F7QEB1   A0A0Y0BIG3   A0A0K8TV87   A0A0B4RY15   A0A194RE38   A0A291P0X6   D5G3F1   D5G3F0   A0A2W1BUX0   A0A2H1VCU4   A0A291P0R0   A0A291P0V0   A0A194PSZ9   A0A2W1BGL8   A0A2A4K7Y3   A0A2W1BMW3   A0A2I6RJN9   A0A2A4JIZ5   D5G3F3   A0A088QEL8   A0A1L8D6M2   A0A194RDX2   D3GDM1   H9JN83   A0A2W1BSV8   A0A1U9X1S5   G1C2I6   A0A291P0Y3   F8V329   A0A1L8D6J3   A0A0C5C1M2   A0A194RJI0   A0A2H1WNU4   A0A2A4JJM6   A0A076FT12   A0A2H1V381   A0A194PRF0   A0A194PT59   A0A194PSA6   A0A291P117   Q1W2E3   A0A291P0V7   A0A194PSE5   A0A2H1WFF3   G3CM70   A0A291P0U0   D5G3F4   A0A0Y0BA98   A0A0K8TVA5   A0A194RDD6   A0A2W1C223   A0A2S0D942   A0A1L8D6J2  

EC Number

3.1.1.-

Pubmed

20060470    19121390    24817326    28756777    26017144    26354079    + More
28986331    26227816    26198868    26778204    24053512    20005949    25803580    23603019   

EMBL

AB299280    BAI66477.1    BABH01033215    KX015872    ARM65401.1    BABH01033219    + More
EU255790    ABX46627.1    KF960778    AII21980.1    KZ150061    PZC74214.1    NWSH01001642    PCG70597.1    KX015873    ARM65402.1    GCVX01000041    JAI18189.1    KX015845    ARM65374.1    PCG70596.1    GCVX01000040    JAI18190.1    KQ460313    KPJ16032.1    MF687624    ATJ44550.1    KY021826    AQY62715.1    JX489387    GEYN01000055    AFQ20792.1    JAV02074.1    JTDY01007971    KOB64827.1    KQ459144    KPJ03728.1    KU375427    APD13869.1    PZC74213.1    ODYU01001848    SOQ38619.1    HQ199328    ADX30519.1    FJ652446    ACV60230.1    KP938873    AKS40354.1    KX015871    ARM65400.1    RSAL01000002    RVE55036.1    RVE55089.1    KU215369    AMB19663.1    KX015869    ARM65398.1    JTDY01009253    KOB63826.1    KU215373    AMB19667.1    JX866739    AGS49143.1    FJ997316    ADF43481.1    DQ401086    ABD62772.1    RVE55035.1    RVE55088.1    PZC74215.1    KY021833    AQY62722.1    KX015870    ARM65399.1    ODYU01009917    SOQ54655.1    MF589742    AXU41412.1    KY021861    AQY62750.1    MF687565    ATJ44491.1    KY021834    AQY62723.1    SOQ38618.1    GCVX01000025    JAI18205.1    LC017767    BAR64781.1    KU215366    AMB19660.1    GCVX01000032    JAI18198.1    KJ023215    AIY69043.1    KPJ16098.1    MF687625    ATJ44551.1    FJ997315    ADF43480.1    FJ997314    ADF43479.1    KZ149909    PZC78161.1    SOQ38621.1    MF687557    ATJ44483.1    MF687563    ATJ44489.1    KQ459595    KPI95889.1    PZC74212.1    NWSH01000066    PCG80014.1    PZC74216.1    KY304476    AUN86407.1    NWSH01001228    PCG72037.1    FJ997317    ADF43482.1    KM008609    AIN76405.1    GEYN01000026    JAV02103.1    KPJ16038.1    FJ652453    ACV60237.1    BABH01033216    PZC78162.1    KY021821    AQY62710.1    JF728805    AEJ38207.1    MF687626    ATJ44552.1    JN019808    AEJ18172.1    GEYN01000056    JAV02073.1    KP001161    AJN91206.1    KPJ16096.1    ODYU01009893    SOQ54612.1    PCG72029.1    KF960782    AII21984.1    ODYU01000269    SOQ34744.1    KPI95887.1    KPI95949.1    KPI95848.1    MF687633    ATJ44559.1    DQ445461    ABE01157.2    MF687564    ATJ44490.1    KPI95888.1    ODYU01008252    SOQ51676.1    HQ122616    AEL33699.1    MF687553    ATJ44479.1    FJ997318    ADF43483.1    KU215371    AMB19665.1    GCVX01000034    JAI18196.1    KQ460323    KPJ15853.1    PZC78163.1    KX015867    ARM65396.1    GEYN01000057    JAV02072.1   

Proteomes

UP000005204    UP000218220    UP000053240    UP000037510    UP000053268    UP000283053    + More

PRIDE

D2KTU3    H9JN73    H9JN84    A9LS22    H9JN83   

Pfam

PF00135   COesterase

Interpro

IPR029058   AB_hydrolase        + More
IPR002018   CarbesteraseB       
IPR019826   Carboxylesterase_B_AS       
IPR019819   Carboxylesterase_B_CS       
IPR002168   Lipase_GDXG_HIS_AS       
IPR000997   Cholinesterase       

SUPFAM

SSF53474   SSF53474       

Gene 3D

3.40.50.1820    

ProteinModelPortal

D2KTU3   H9JN73   A0A2S0D881   H9JN84   A9LS22   A0A076FRM1   + More
A0A2W1BKQ4   A0A2A4JEW3   A0A2U3T8L5   A0A0K8TUL7   A0A2U3T8J6   A0A2A4JFQ0   A0A0K8TVU9   A0A194REM3   A0A291P123   A0A1U9X1T3   J7HWI3   A0A0L7KNG8   A0A194QDV9   A0A1J0M1C9   A0A2W1BR44   A0A2H1VCP7   F1C4B8   D3GDL4   A0A0K0XRL4   A0A2U3T8L4   A0A3S2MAW7   A0A0Y0B016   A0A2U3T8L2   A0A0L7KL89   A0A109QN31   U5KKB6   D5G3F2   A3QR02   A0A3S2TTT0   A0A2W1BKK3   A0A1U9X1T8   A0A2U3T8L3   A0A2H1WNK8   A0A346TPC2   A0A1U9X1X0   A0A291P0Q3   A0A1U9X1U2   A0A2H1VCP1   A0A0K8TVW5   A0A0F7QEB1   A0A0Y0BIG3   A0A0K8TV87   A0A0B4RY15   A0A194RE38   A0A291P0X6   D5G3F1   D5G3F0   A0A2W1BUX0   A0A2H1VCU4   A0A291P0R0   A0A291P0V0   A0A194PSZ9   A0A2W1BGL8   A0A2A4K7Y3   A0A2W1BMW3   A0A2I6RJN9   A0A2A4JIZ5   D5G3F3   A0A088QEL8   A0A1L8D6M2   A0A194RDX2   D3GDM1   H9JN83   A0A2W1BSV8   A0A1U9X1S5   G1C2I6   A0A291P0Y3   F8V329   A0A1L8D6J3   A0A0C5C1M2   A0A194RJI0   A0A2H1WNU4   A0A2A4JJM6   A0A076FT12   A0A2H1V381   A0A194PRF0   A0A194PT59   A0A194PSA6   A0A291P117   Q1W2E3   A0A291P0V7   A0A194PSE5   A0A2H1WFF3   G3CM70   A0A291P0U0   D5G3F4   A0A0Y0BA98   A0A0K8TVA5   A0A194RDD6   A0A2W1C223   A0A2S0D942   A0A1L8D6J2  

PDB

5TYP     E-value=1.88512e-70,     Score=677

KEGG

100329150    no KO assigned | (RefSeq) cce-1, Bmcce-1; carboxyl/cholinesterase 1

GO

GO:0016787   GO:0004104  

SignalP

Position:   1 - 16,         Likelihood:  0.848878

 

 

Length:

552

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.01167

Exp number, first 60 AAs:

0.00932

Total prob of N-in:

0.00054

outside

1  -  552

 

 

Pi

284.428523

Theta

210.320559

Tajima's D

1.263721

CLR

0.182064

CSRT

0.728663566821659

Interpretation

Uncertain