Gene

KWMTBOMO13525

Pre Gene Modal

BGIBMGA001309

Annotation

PREDICTED:_cytochrome_c_oxidase_assembly_protein_COX15_homolog_isoform_X1_[Bombyx_mori]

Location

Bomo_Chr23(-):698739-710847      View in EpiBrowser

Location in the cell

PlasmaMembrane   Reliability : 3.438

CDS

ATGCCTAAGATTCTATTCATCAGTATACCTAACAGTTGTACAGCTATGCTGAACCTCTCACGACTTTGTCGATGTAAGCAGTCTCTAAGTGCAGTGCAAAGTAAACTCCTGGTGTCATCTCGAAATGGCTTCAGTAACAGTATTATTTCAAGGCAAATTATCACAACTACAAAAATGCACAGATATAACATCCTAGGAAGGTTCAGTCTAAGCAGCACAATAAAATCAAACAGTATTATAATGCGATTTTGCTCTTCAACTCCTAAACCGAAGACGTCAAGAGCAGTTGGATACTGGCTACTAGGATGCAGTGGTATGGTCTTCACTGCTGTAGTACTAGGTGGCGTCACCCGACTGACAGAGTCAGGTTTGTCTATGGTCACGTGGAGACTCCTCGGAGAGAAGATGCCCACGAATGAAGAGGAGTGGCAAAAAGAGTTCGAGAAGTATCAGCAGTATCCAGAGTTTAAATACAAAAATCAGAACATAACATTCTCAGACTTCAAATGGATATGGTACATGGAGTTCGCTCACCGAACCTGGGGCCGAGCCATCGGAGCCGCCATGTTCCTCCCCGCCGCCTACTTCTGGTACCGGGGAATGCTCCTCCCGGACATGAAGATCAGGGTCGCCGTATACTGCGGCTTAGTGGCTGCTCAGGGGCTGATGGGCTGGTACATGGTGAAATCAGGATTGGAAGACAGGTTCCATGGACCTTCAGATGTCCCGAGGGTCTCGCAATACAGGCTCGCCGCGCACTTAAGTCTGGCGTTCATATTGTACGCGGGATTACTTGGCGGAGCCCTGAGGGTGCTCCGCCCCTTCCCGGCGGCGGCTACTTTGCAGAAAATCAAGGAGTTGAAGAGCATCACCGGCCTCGCGCACGCCGTCAAGGCGATGACTTTCATCACGGCCGTCTCCGGAGCCTTCGTGGCGGGTCTGGACGCAGGCCTGGTCTACAATTCCTTCCCCAAAATGGGAGACAATTGGCTTCCCGATGACATCTTGGCATTCTCACCCACAATCAAGAACTTTACCGAGAACCCGACTACCGTGCAGTTCGACCACCGCGTGCTGGGCGCCAGCACCCTAGCGGCGGCCAGCACGCTGTGGTTGCTGTCGCGCAGGAGGCCGCTGTCCCCGGGCGCCCGGGCCGCCGCGCGCGCCCTCGCCGCCATGGCCTGGATGCAGGCGGGGCTGGGCGTGGCCACGCTGCTGTGCTACGTGCCCACTGCGCTGGCGGCGAGCCACCAGGCGGGCTCGCTGGTGCTGCTGTCGCTGGCCGTGTGGCTCACGCACGAGGTCAAGCTGCTCAAGTACATACCCAAGTAG

Protein

MPKILFISIPNSCTAMLNLSRLCRCKQSLSAVQSKLLVSSRNGFSNSIISRQIITTTKMHRYNILGRFSLSSTIKSNSIIMRFCSSTPKPKTSRAVGYWLLGCSGMVFTAVVLGGVTRLTESGLSMVTWRLLGEKMPTNEEEWQKEFEKYQQYPEFKYKNQNITFSDFKWIWYMEFAHRTWGRAIGAAMFLPAAYFWYRGMLLPDMKIRVAVYCGLVAAQGLMGWYMVKSGLEDRFHGPSDVPRVSQYRLAAHLSLAFILYAGLLGGALRVLRPFPAAATLQKIKELKSITGLAHAVKAMTFITAVSGAFVAGLDAGLVYNSFPKMGDNWLPDDILAFSPTIKNFTENPTTVQFDHRVLGASTLAAASTLWLLSRRRPLSPGARAAARALAAMAWMQAGLGVATLLCYVPTALAASHQAGSLVLLSLAVWLTHEVKLLKYIPK

Description

Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.

Subunit

Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.

Similarity

Belongs to the tubulin family.

Uniprot

A0A2A4JPB2   A0A2W1BWW9   A0A2H1WLH8   A0A212F8L1   H9IVM8   A0A194PT37   + More
A0A194RJD8   A0A1L8DZT3   A0A182JDD7   A0A1Q3FA69   B0XEF3   A0A1B0CF23   A0A182HLR1   A0A182TEF2   A0A182UNP1   Q7PY48   A0A1B0CF25   Q16M46   A0A182WSV7   A0A182G895   A0A182VRT1   A0A182XUZ6   A0A182FNK0   A0A2M4ASV6   A0A2M4ASC5   A0A2M4AT35   A0A182P2L8   D6WC54   A0A182Q3M0   A0A182JU49   W5J6F0   A0A182N7C6   A0A336LV93   A0A1B6FST8   A0A1B6GQ20   A0A0T6BC05   A0A1J1IG55   A0A2J7QSK3   A0A084W313   N6T4Q8   A0A226DJX6   A0A088AF49   A0A2A3ET21   A0A0M3QVM1   B4LNZ9   A0A1B6D8M1   A0A2R7VXF5   A0A182RPD4   A0A224XM20   A0A310SF74   B4KMB5   A0A023F3W2   A0A1W4X7F6   A0A0V0G622   E9J0W9   A0A154PST3   B4J657   B4MRM8   A0A069DTE2   A0A067QII1   A0A0L7QYJ7   B3MCN3   U4TTF8   A0A0P4VM07   A0A3B0IYL2   A0A1A9XZM5   A0A1B0B9Z3   Q292P6   Q9W1F5   B3NQ31   A0A1Y1JZ73   A0A1A9ZV19   U5EGU3   B4PAA7   B4QBF2   A0A0A9XXQ9   B4GCZ7   B4I8X3   F4WTT0   A0A1W4UMZ0   A0A1I8MIW6   A0A1A9V6G0   A0A1B0G7D8   A0A151XGK0   A0A1A9W121   A0A195F8W3   A0A151ICZ5   A0A1I8PRB3   D3TL67   A0A3B0IYU7   A0A151ISM5   T1GP24   A0A158N9N7   E0VSM3   A0A2S2PS90   A0A2H8TPY7   T1PJ17  

Pubmed

28756777    22118469    19121390    26354079    12364791    14747013    + More
17210077    17510324    26483478    25244985    18362917    19820115    20920257    23761445    24438588    23537049    17994087    25474469    21282665    26334808    24845553    27129103    15632085    10731132    12537568    12537572    12537573    12537574    16110336    17569856    17569867    26109357    26109356    28004739    17550304    22936249    25401762    26823975    21719571    25315136    20353571    21347285    20566863   

EMBL

NWSH01000983    PCG73250.1    KZ149964    PZC76243.1    ODYU01009461    SOQ53919.1    + More
AGBW02009702    OWR50086.1    BABH01039660    BABH01039661    BABH01039662    KQ459595    KPI95929.1    KQ460313    KPJ16056.1    GFDF01002076    JAV12008.1    GFDL01010595    JAV24450.1    DS232825    EDS25950.1    AJWK01009599    APCN01000911    AAAB01008987    EAA00923.3    AJWK01009600    CH477880    EAT35410.1    JXUM01151654    KQ571269    KXJ68213.1    GGFK01010377    MBW43698.1    GGFK01010356    MBW43677.1    GGFK01010644    MBW43965.1    KQ971316    EEZ97849.1    AXCN02000143    ADMH02002001    ETN60022.1    UFQS01000011    UFQT01000011    SSW97182.1    SSX17568.1    GECZ01016535    JAS53234.1    GECZ01029066    GECZ01005244    JAS40703.1    JAS64525.1    LJIG01002109    KRT84831.1    CVRI01000049    CRK99195.1    NEVH01011876    PNF31568.1    ATLV01019778    ATLV01019779    KE525279    KFB44607.1    APGK01052516    KB741213    ENN72593.1    LNIX01000017    OXA45845.1    KZ288185    PBC34878.1    CP012524    ALC42633.1    CH940648    EDW61168.1    GEDC01015254    JAS22044.1    KK854147    PTY12142.1    GFTR01005558    JAW10868.1    KQ765222    OAD54068.1    CH933808    EDW09803.1    GBBI01002611    JAC16101.1    GECL01002609    JAP03515.1    GL767538    EFZ13509.1    KQ435180    KZC14976.1    CH916367    EDW01915.1    CH963850    EDW74767.1    GBGD01001863    JAC87026.1    KK853313    KDR08630.1    KQ414688    KOC63668.1    CH902619    EDV36267.1    KB631625    ERL84809.1    GDKW01002825    JAI53770.1    OUUW01000001    SPP73184.1    JXJN01010642    CM000071    EAL24815.2    AE013599    AY071468    AAF47112.1    AAL49090.1    CH954179    EDV56904.1    GEZM01096723    JAV54624.1    GANO01003303    JAB56568.1    CM000158    EDW92433.1    CM000362    CM002911    EDX08470.1    KMY96185.1    GBHO01019972    GBHO01019971    GBHO01019970    GBRD01012765    GBRD01012764    GBRD01012763    GDHC01012035    GDHC01010528    GDHC01009695    GDHC01000321    JAG23632.1    JAG23633.1    JAG23634.1    JAG53059.1    JAQ06594.1    JAQ08101.1    JAQ08934.1    JAQ18308.1    CH479181    EDW31535.1    CH480824    EDW57048.1    GL888344    EGI62395.1    CCAG010021560    KQ982169    KYQ59532.1    KQ981727    KYN36652.1    KQ977991    KYM98285.1    EZ422168    ADD18362.1    SPP73185.1    KQ981064    KYN09885.1    CAQQ02137561    ADTU01009724    ADTU01009725    DS235751    EEB16379.1    GGMR01019710    MBY32329.1    GFXV01004254    MBW16059.1    KA648110    AFP62739.1   

Proteomes

UP000218220    UP000007151    UP000005204    UP000053268    UP000053240    UP000075880    + More
UP000002320    UP000092461    UP000075840    UP000075902    UP000075903    UP000007062    UP000008820    UP000076407    UP000069940    UP000249989    UP000075920    UP000076408    UP000069272    UP000075885    UP000007266    UP000075886    UP000075881    UP000000673    UP000075884    UP000183832    UP000235965    UP000030765    UP000019118    UP000198287    UP000005203    UP000242457    UP000092553    UP000008792    UP000075900    UP000009192    UP000192223    UP000076502    UP000001070    UP000007798    UP000027135    UP000053825    UP000007801    UP000030742    UP000268350    UP000092443    UP000092460    UP000001819    UP000000803    UP000008711    UP000092445    UP000002282    UP000000304    UP000008744    UP000001292    UP000007755    UP000192221    UP000095301    UP000078200    UP000092444    UP000075809    UP000091820    UP000078541    UP000078542    UP000095300    UP000078492    UP000015102    UP000005205    UP000009046   

PRIDE

H9IVM8    Q9W1F5   

Pfam

PF02628   COX15-CtaA        + More
PF03953   Tubulin_C
PF00091   Tubulin

Interpro

IPR009003   Peptidase_S1_PA        + More
IPR003780   COX15/CtaA_fam       
IPR023754   HemeA_Synthase_type2       
IPR017975   Tubulin_CS       
IPR002452   Alpha_tubulin       
IPR037103   Tubulin/FtsZ_C_sf       
IPR008280   Tub_FtsZ_C       
IPR003008   Tubulin_FtsZ_GTPase       
IPR018316   Tubulin/FtsZ_2-layer-sand-dom       
IPR000217   Tubulin       
IPR036525   Tubulin/FtsZ_GTPase_sf       

SUPFAM

SSF50494   SSF50494        + More
SSF52490   SSF52490       
SSF55307   SSF55307       

Gene 3D

3.30.1330.20     3.40.50.1440    

ProteinModelPortal

A0A2A4JPB2   A0A2W1BWW9   A0A2H1WLH8   A0A212F8L1   H9IVM8   A0A194PT37   + More
A0A194RJD8   A0A1L8DZT3   A0A182JDD7   A0A1Q3FA69   B0XEF3   A0A1B0CF23   A0A182HLR1   A0A182TEF2   A0A182UNP1   Q7PY48   A0A1B0CF25   Q16M46   A0A182WSV7   A0A182G895   A0A182VRT1   A0A182XUZ6   A0A182FNK0   A0A2M4ASV6   A0A2M4ASC5   A0A2M4AT35   A0A182P2L8   D6WC54   A0A182Q3M0   A0A182JU49   W5J6F0   A0A182N7C6   A0A336LV93   A0A1B6FST8   A0A1B6GQ20   A0A0T6BC05   A0A1J1IG55   A0A2J7QSK3   A0A084W313   N6T4Q8   A0A226DJX6   A0A088AF49   A0A2A3ET21   A0A0M3QVM1   B4LNZ9   A0A1B6D8M1   A0A2R7VXF5   A0A182RPD4   A0A224XM20   A0A310SF74   B4KMB5   A0A023F3W2   A0A1W4X7F6   A0A0V0G622   E9J0W9   A0A154PST3   B4J657   B4MRM8   A0A069DTE2   A0A067QII1   A0A0L7QYJ7   B3MCN3   U4TTF8   A0A0P4VM07   A0A3B0IYL2   A0A1A9XZM5   A0A1B0B9Z3   Q292P6   Q9W1F5   B3NQ31   A0A1Y1JZ73   A0A1A9ZV19   U5EGU3   B4PAA7   B4QBF2   A0A0A9XXQ9   B4GCZ7   B4I8X3   F4WTT0   A0A1W4UMZ0   A0A1I8MIW6   A0A1A9V6G0   A0A1B0G7D8   A0A151XGK0   A0A1A9W121   A0A195F8W3   A0A151ICZ5   A0A1I8PRB3   D3TL67   A0A3B0IYU7   A0A151ISM5   T1GP24   A0A158N9N7   E0VSM3   A0A2S2PS90   A0A2H8TPY7   T1PJ17  

KEGG

101739736    K02259 cytochrome c oxidase assembly protein subunit 15 | (RefSeq) cytochrome c oxidase assembly pro

PATHWAY

00190    Oxidative phosphorylation - Bombyx mori (domestic silkworm)
00860    Porphyrin and chlorophyll metabolism - Bombyx mori (domestic silkworm)
01100    Metabolic pathways - Bombyx mori (domestic silkworm)

GO

GO:0016021   GO:0016627   GO:0006784   GO:0003924   GO:0005737   GO:0005200   GO:0007017   GO:0005874   GO:0005525   GO:0005743   GO:0016653   GO:0008235   GO:0019538   GO:0030145   GO:0003676   GO:0016491   GO:0015930   GO:0055114  

PANTHER

PTHR23289   PTHR11588  

Subcellular location

  

Length:

443

Number of predicted TMHs:

7

Exp number of AAs in TMHs:

153.19598

Exp number, first 60 AAs:

2.2429

Total prob of N-in:

0.84938

inside

1  -  94

TMhelix

95  -  117

outside

118  -  180

TMhelix

181  -  203

inside

204  -  209

TMhelix

210  -  228

outside

229  -  249

TMhelix

250  -  272

inside

273  -  291

TMhelix

292  -  314

outside

315  -  356

TMhelix

357  -  374

inside

375  -  393

TMhelix

394  -  416

outside

417  -  443

 

 

Pi

270.785156

Theta

190.18256

Tajima's D

1.404478

CLR

0.196761

CSRT

0.763161841907905

Interpretation

Uncertain