Gene

KWMTBOMO13493  Validated by peptides from experiments

Pre Gene Modal

BGIBMGA009189

Annotation

Prefoldin_subunit_2_[Operophtera_brumata]

Location

Bomo_Chr23(+):177181-178055      View in EpiBrowser

Full name

Prefoldin subunit 2      

Location in the cell

Cytoplasmic   Reliability : 2.146 Nuclear   Reliability : 1.578

CDS

ATGGAGTTAAACGAACATAAGATCGTAATTGAGACTTTGCGGGGAGTGGAGTTGACCCGTAAGTGTTTCCGGATGTTTGGGGGCGTGCTTGTCGAACGCACCGTAGCTGAGGTGTTGCCAGAGCTGATCAGCAATTATGAACAGCTACCTAAGGCCATCCAGTCCCTAGAAGACCAACTCACTCAGAAGGGAGAGGAGATCAATAAATACATTGAGGAACATGATATTCGCATCCAACGTGCTGATCGCACCATGCCTGAACCACCTCCAGAGCAATCCACCTCTACCAAGTCTAATGTGCTAGTTGCTAGCGGTTAA

Protein

MELNEHKIVIETLRGVELTRKCFRMFGGVLVERTVAEVLPELISNYEQLPKAIQSLEDQLTQKGEEINKYIEEHDIRIQRADRTMPEPPPEQSTSTKSNVLVASG

Description

Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. Binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins.
Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. Binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins (By similarity).

Subunit

Binds to c-Myc; interacts with its N-terminal domain (By similarity). Heterohexamer of two PFD-alpha type and four PFD-beta type subunits. Interacts with URI1; the interaction is phosphorylation-dependent and occurs in a growth-dependent manner.
Heterohexamer of two PFD-alpha type and four PFD-beta type subunits. Binds to c-Myc; interacts with its N-terminal domain. Interacts with URI1; the interaction is phosphorylation-dependent and occurs in a growth-dependent manner (By similarity).
Interacts with URI1; the interaction is phosphorylation-dependent and occurs in a growth-dependent manner (By similarity). Heterohexamer of two PFD-alpha type and four PFD-beta type subunits. Binds to c-Myc; interacts with its N-terminal domain.

Similarity

Belongs to the prefoldin subunit beta family.

Keywords

Chaperone   Complete proteome   Cytoplasm   Mitochondrion   Nucleus   Reference proteome  

Feature

chain  Prefoldin subunit 2

Uniprot

H9JI41   A0A2H1VM24   A0A2W1B4U1   A0A2A4J137   A0A1E1WBX3   A0A0L7KPI6   + More
S4NNF3   A0A212FEH9   A0A194RFK6   I4DKB4   A0A1J1I6C0   E2A1G9   A0A151K128   A0A0J7L3P3   A0A151J3L6   F4WHK2   A0A158N905   A0A026VSX7   A0A164PAT2   E2C438   A0A151IBK7   M7B729   A0A0P5FJH6   A0A0K8TS45   C1BSY2   A0A088AGW5   A0A2A3ETN3   V9IIP1   E9H6W9   A0A0P6C8H6   A0A0L7QWL4   A0A210Q0N7   V4A887   A0A0P6I4J1   B1H3F2   T1IHB3   C3Y0W8   F6V699   A0A1I8MQB1   A0A154P6M6   A0A3Q7PK43   C3YJY7   A0A1S3GB48   A0A3M7P239   G1MAQ8   A0A151MRJ1   A0A226MEY1   A0A2G9QIJ5   A0A286Y0R6   V5IAN6   L5LTW9   A0A1U7QYR3   A0A0P4VVP7   G1P2M1   A0A1U7R6N6   A0A1L8E839   D2I0T7   A0A2T7P0I9   M3YS00   A0A1L8EE83   A0A232EUR4   K7JA86   A0A250XVB3   A0A2P8XVC5   M3WGQ1   A0A1Y1N3A9   F6YLE9   F6W739   A0A2K6D0D3   A0A2K6JYG4   A0A2K5V9W8   G1RUR1   A0A2K5ZL84   A0A0D9S3H2   A0A2Y9EAC2   A0A2R9AYJ1   A0A096MRW1   A0A2K6RUA8   A0A2K5MA66   H0WUS6   A0A2K5IJL8   A0A2K6F995   H2N523   H2Q0F8   F6V169   B1AQP2   Q9UHV9   A0A034VYG9   L8YDV3   G5E1D4   L8HRH0   W5PID4   A0A212CGL8   A1A4P5   F1S192   Q862M6   G1SHF1   A0A226NUT8   I3M7R5   O70591  

Pubmed

19121390    28756777    26227816    23622113    22118469    26354079    + More
22651552    20798317    21719571    21347285    24508170    30249741    23624526    26369729    21292972    28812685    23254933    18563158    20431018    25315136    30375419    20010809    22293439    21993624    28648823    20075255    28087693    29403074    17975172    28004739    17495919    19892987    22722832    25362486    16136131    17431167    22002653    25319552    11181995    10931946    11042152    15489334    9630229    17936702    21269460    25348373    23385571    22751099    20809919    30723633    12658628    24621616    21183079   

EMBL

BABH01041181    ODYU01003125    SOQ41492.1    KZ150327    PZC71382.1    NWSH01003813    + More
PCG65795.1    GDQN01006605    JAT84449.1    JTDY01007718    KOB64986.1    GAIX01012279    JAA80281.1    AGBW02008933    OWR52142.1    KQ460313    KPJ16080.1    AK401732    KQ459595    BAM18354.1    KPI95906.1    CVRI01000043    CRK95845.1    GL435766    EFN72642.1    KQ981229    KYN44341.1    LBMM01000785    KMQ97502.1    KQ980290    KYN16917.1    GL888161    EGI66356.1    ADTU01009011    KK108326    QOIP01000004    EZA46755.1    RLU23361.1    LRGB01002648    KZS06665.1    GL452364    EFN77424.1    KQ978095    KYM97023.1    KB565896    EMP27988.1    GDIQ01254465    JAJ97259.1    GDAI01000429    JAI17174.1    BT077711    BT120571    BT121940    HACA01009824    ACO12135.1    ADD24211.1    ADD38870.1    CDW27185.1    KZ288189    PBC34642.1    JR046359    AEY60179.1    GL732599    EFX72493.1    GDIP01007200    JAM96515.1    KQ414713    KOC62956.1    NEDP02005298    OWF42310.1    KB202591    ESO89496.1    GDIQ01011479    JAN83258.1    BC161373    AAI61373.1    JH429822    GG666479    EEN66101.1    AAMC01133308    KQ434827    KZC07596.1    GG666520    EEN59444.1    REGN01014039    RMZ93146.1    ACTA01073769    AKHW03005309    KYO27157.1    MCFN01001066    OXB53790.1    KV981459    PIO15335.1    AAKN02043132    AAKN02043133    GALX01000870    JAB67596.1    KB107990    ELK29487.1    GDRN01124704    JAI56694.1    AAPE02047223    AAPE02047224    AAPE02047225    AAPE02047226    AAPE02047227    AAPE02047228    AAPE02047229    GFDG01003975    JAV14824.1    GL193920    EFB27740.1    PZQS01000007    PVD26923.1    AEYP01088003    AEYP01088004    GFDG01001777    JAV17022.1    NNAY01002098    OXU22090.1    AAZX01006344    GFFV01004642    JAV35303.1    PYGN01001290    PSN35961.1    AANG04004454    GEZM01013807    JAV92319.1    AQIA01002038    ADFV01184071    ADFV01184072    ADFV01184073    ADFV01184074    ADFV01184075    AQIB01138704    AQIB01138705    AJFE02037540    AJFE02037541    AHZZ02017077    AAQR03039455    AAQR03039456    AAQR03039457    AAQR03039458    AAQR03039459    AAQR03039460    AAQR03039461    AAQR03039462    ABGA01295258    ABGA01295259    NDHI03003420    PNJ57076.1    AACZ04025384    GABF01007593    GABD01010716    NBAG03000493    JAA14552.1    JAA22384.1    PNI19817.1    JSUE03002659    JSUE03002660    JV043603    CM001253    AFI33674.1    EHH15435.1    AK315736    CH471121    BAG38091.1    EAW52658.1    AF117237    AF165883    AF151065    BC012464    BC047042    GAKP01012032    JAC46920.1    KB362198    ELV13279.1    JP287198    AEQ18144.1    JH883435    ELR46491.1    AMGL01005212    MKHE01000020    OWK05131.1    BC126786    AEMK02000022    DQIR01192919    HDB48396.1    AB098954    BAC56444.1    AAGW02000266    AWGT02000669    OXB71087.1    AGTP01116358    AGTP01116359    Y17393    BC026839    BC049606   

Proteomes

UP000005204    UP000218220    UP000037510    UP000007151    UP000053240    UP000053268    + More
UP000183832    UP000000311    UP000078541    UP000036403    UP000078492    UP000007755    UP000005205    UP000053097    UP000279307    UP000076858    UP000008237    UP000078542    UP000031443    UP000005203    UP000242457    UP000000305    UP000053825    UP000242188    UP000030746    UP000001554    UP000008143    UP000095301    UP000076502    UP000286641    UP000081671    UP000276133    UP000008912    UP000050525    UP000198323    UP000005447    UP000189706    UP000001074    UP000245119    UP000000715    UP000215335    UP000002358    UP000245037    UP000011712    UP000002280    UP000002281    UP000233120    UP000233180    UP000233100    UP000001073    UP000233140    UP000029965    UP000248480    UP000240080    UP000028761    UP000233200    UP000233060    UP000005225    UP000233080    UP000233160    UP000001595    UP000002277    UP000006718    UP000005640    UP000011518    UP000002356    UP000009136    UP000008227    UP000001811    UP000198419    UP000005215    UP000000589   

PRIDE

H9JI41    Q9UHV9    A1A4P5    F1S192    O70591   

Pfam

PF01920   Prefoldin_2

Interpro

IPR002777   PFD_beta-like        + More
IPR009053   Prefoldin       
IPR027235   PFD2       

Gene 3D

1.10.287.370    

ProteinModelPortal

H9JI41   A0A2H1VM24   A0A2W1B4U1   A0A2A4J137   A0A1E1WBX3   A0A0L7KPI6   + More
S4NNF3   A0A212FEH9   A0A194RFK6   I4DKB4   A0A1J1I6C0   E2A1G9   A0A151K128   A0A0J7L3P3   A0A151J3L6   F4WHK2   A0A158N905   A0A026VSX7   A0A164PAT2   E2C438   A0A151IBK7   M7B729   A0A0P5FJH6   A0A0K8TS45   C1BSY2   A0A088AGW5   A0A2A3ETN3   V9IIP1   E9H6W9   A0A0P6C8H6   A0A0L7QWL4   A0A210Q0N7   V4A887   A0A0P6I4J1   B1H3F2   T1IHB3   C3Y0W8   F6V699   A0A1I8MQB1   A0A154P6M6   A0A3Q7PK43   C3YJY7   A0A1S3GB48   A0A3M7P239   G1MAQ8   A0A151MRJ1   A0A226MEY1   A0A2G9QIJ5   A0A286Y0R6   V5IAN6   L5LTW9   A0A1U7QYR3   A0A0P4VVP7   G1P2M1   A0A1U7R6N6   A0A1L8E839   D2I0T7   A0A2T7P0I9   M3YS00   A0A1L8EE83   A0A232EUR4   K7JA86   A0A250XVB3   A0A2P8XVC5   M3WGQ1   A0A1Y1N3A9   F6YLE9   F6W739   A0A2K6D0D3   A0A2K6JYG4   A0A2K5V9W8   G1RUR1   A0A2K5ZL84   A0A0D9S3H2   A0A2Y9EAC2   A0A2R9AYJ1   A0A096MRW1   A0A2K6RUA8   A0A2K5MA66   H0WUS6   A0A2K5IJL8   A0A2K6F995   H2N523   H2Q0F8   F6V169   B1AQP2   Q9UHV9   A0A034VYG9   L8YDV3   G5E1D4   L8HRH0   W5PID4   A0A212CGL8   A1A4P5   F1S192   Q862M6   G1SHF1   A0A226NUT8   I3M7R5   O70591  

KEGG

101744616    K09549 prefoldin subunit 2 | (RefSeq) prefoldin subunit 2

GO

GO:0006457   GO:0051082   GO:0016272   GO:0005737   GO:0044183   GO:0051495   GO:0005634   GO:0005829   GO:0005739   GO:0005886   GO:0007155   GO:0048869   GO:0003676   GO:0016491   GO:0015930  

PANTHER

PTHR13303  

Subcellular location

Nucleus  
Cytoplasm  
Mitochondrion  

Length:

105

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.0013

Exp number, first 60 AAs:

0.0013

Total prob of N-in:

0.20193

outside

1  -  105

 

 

Pi

231.034734

Theta

193.564008

Tajima's D

0.609255

CLR

0.089168

CSRT

0.546472676366182

Interpretation

Uncertain