Gene

KWMTBOMO13400

Annotation

PREDICTED:_GPN-loop_GTPase_1-like_[Bombyx_mori]

Location

Bomo_Chr22(-):16153365-16159042      View in EpiBrowser

Full name

GPN-loop GTPase      

Location in the cell

Cytoplasmic   Reliability : 2.114 Nuclear   Reliability : 1.582

CDS

ATGTCTTCCGATACAAATAAACCAGAAGGTTCAAACGCGGAGCCCAACAAACCCATTTGTTTGATAATTTTAGGTATGGCCGGCGCTGGAAAGACTTCCTTCACACGTCGATTGTCAAATAAAGTTATTAATGGATCACGACCTTATCTAGTGAACTTGGATCCAGCTTGCAGGGAAGTACCTTATCCTGCCAACATTGATATAAGAGATACTGTAGACTATAAAGAAGTAATGAAGCAGTATGGTCTTGGACCAAATGGTGGTATAGTTACAGCACTGAATCTGTTTTCAACAAAATTTGGACAAGTCGTAGACTTGATAGAGAAAGCGGGAAAGAAACACAAGTACTGTGTTATCGATACGCCAGGTCAAATAGAAGTGTTCACATGGTCAGCATCAGGCACAATAGTGACAGAAACACTGGCGTCATGCTGTCCCACAGTCGTAGTGTATGTAATGGACACAGTACGCAGTGTGTCGCCCGTCACATTTATGTCCAACATGCTGTATGCTTGCTCAATATTGTACAAGACTCGGCTGCCGTTTATTGTTGTCATGAATAAAATCGATGTAGTAAACAATTCATACGCAGTGGAATGGATGAGAGATTTCGAAGCTTTCCAAGAAGCATTAAATGCAGATGGTGGGGGAGAGACGGAAGGAGGAAATACTTACATAGGAAACTTGACACAGTCCATGGCACTGGCGTTGGACAGTTTTTATTCAGATCTGAAGTGCTGTGGTGTGAGTGCGCATACCGGTGAAGGCATAGATGAGTTCTTCAAACTAGTTGATGAATCTGCAGAGGAATATGAAAGAGAATACAAAGCGGATTGGTTGAAAATGCGCGCTGAAAAATTGGCAGAAGAGAAACGAAGGAAAGAAGATGAATTAAAAAAGACAGACAGCGTGGAGACAGTTATAGACAAGAAGAGTTTGATAGATGAAGTGCCGATCGGCAGAGAGCTCAGCGACATGTACCTGAAGCACCCCGGCAACGAGAGCTCCAGCGACGACGAGGGAACTGAAAATGAACCGGAAATCGACGACAAACCAGAGGACGTGGCTATGTTCCAAGAGTTCTTAAAGAAACACATAAAACCTAATGACACGCAGAAATAA

Protein

MSSDTNKPEGSNAEPNKPICLIILGMAGAGKTSFTRRLSNKVINGSRPYLVNLDPACREVPYPANIDIRDTVDYKEVMKQYGLGPNGGIVTALNLFSTKFGQVVDLIEKAGKKHKYCVIDTPGQIEVFTWSASGTIVTETLASCCPTVVVYVMDTVRSVSPVTFMSNMLYACSILYKTRLPFIVVMNKIDVVNNSYAVEWMRDFEAFQEALNADGGGETEGGNTYIGNLTQSMALALDSFYSDLKCCGVSAHTGEGIDEFFKLVDESAEEYEREYKADWLKMRAEKLAEEKRRKEDELKKTDSVETVIDKKSLIDEVPIGRELSDMYLKHPGNESSSDDEGTENEPEIDDKPEDVAMFQEFLKKHIKPNDTQK

Description

Small GTPase required for proper nuclear import of RNA polymerase II (RNAPII). May act at an RNAP assembly step prior to nuclear import.

Subunit

Binds to RNA polymerase II.

Similarity

Belongs to the GPN-loop GTPase family.

Uniprot

A0A2H1V049   A0A194REB6   A0A194PYG7   A0A3S2L685   A0A212ES60   A0A1E1W6Y9   + More
S4PKV9   Q16TZ7   B0W660   A0A1Q3F4C3   A0A1Q3F4A8   A0A182GD34   A0A0M8ZXM4   A0A232EX19   K7IRL7   A0A154NXX6   A0A195F0K8   A0A0C9RCV1   A0A1J1HH57   E1ZX65   E9IEA5   A0A0T6B659   A0A195BYY8   A0A158P3K0   A0A1I8M785   A0A1B6CA99   A0A088ANI7   A0A067R7P6   A0A0L7R128   A0A1B6G7E8   A0A2A3EHW7   U5EIA7   A0A2J7R8A3   A0A0J7L9Q7   E2BLZ3   A0A182PNV1   A0A151IH85   A0A182YDY3   A0A151IV51   A0A1B6IYN3   A0A1A9W8R4   A0A1B0DQV1   A0A1A9USZ5   A0A182FLY6   A0A182QS09   A0A1B0FHM2   A0A182NP70   A0A2P8Y1P6   A0A182G371   A0A1A9Z6C1   A0A1L8DWV2   A0A151XDL8   A0A1A9XNK6   F4WAT3   A0A182RWX9   A0A084VJI3   A0A0K8TTP7   A0A1I8NY79   A0A1B0BNV4   W5JCN2   A0A2M4AM18   A0A182W7X2   A0A182LYH5   A0A2M4BRB5   A0A182J789   A0A1B0CFG7   A0A1W4X8C9   A0A182SLD7   A0A1W4X747   A0A0K8W8M5   A0A0L0BZ32   W8CCV9   D2A4G3   A0A2M4BS91   A0A2M4BSI3   A0A2R7VTM9   A0A3B5AIY4   A0A1W5ACE9   A0A1W5AKN7   A0A0A1WTT9   A0A1S3RAU2   A0A0S7LWP7   A0A210PG82   A0A3B3Y372   A0A3Q0JGC9   A0A3B3W2H1   A0A087X2N6   G3Q0C1   A0A3P8RL57   A0A2D0RMY4   A0A315VV76   A0A1Y1NK86   G3Q0C4   A0A3Q2X6R5   A0A3B4TU02   A0A147ARZ8   A0A3Q1IXY4   A0A3S2N614  

EC Number

3.6.5.-

Pubmed

26354079    22118469    23622113    17510324    26483478    28648823    + More
20075255    20798317    21282665    21347285    25315136    24845553    25244985    29403074    21719571    24438588    26369729    20920257    23761445    26108605    24495485    18362917    19820115    25830018    28812685    29703783    28004739   

EMBL

ODYU01000073    SOQ34215.1    KQ460323    KPJ15932.1    KQ459586    KPI98068.1    + More
RSAL01000124    RVE46613.1    AGBW02012888    OWR44284.1    GDQN01008337    JAT82717.1    GAIX01004320    JAA88240.1    CH477636    EAT37997.1    DS231847    EDS36407.1    GFDL01012676    JAV22369.1    GFDL01012682    JAV22363.1    JXUM01160707    KQ573791    KXJ67903.1    KQ435833    KOX71673.1    NNAY01001793    OXU22906.1    KQ434782    KZC04526.1    KQ981880    KYN33896.1    GBYB01006120    JAG75887.1    CVRI01000002    CRK86890.1    GL435030    EFN74155.1    GL762576    EFZ21091.1    LJIG01009583    KRT82790.1    KQ976394    KYM93136.1    ADTU01008166    GEDC01026944    GEDC01011887    JAS10354.1    JAS25411.1    KK852685    KDR18496.1    KQ414668    KOC64553.1    GECZ01011438    JAS58331.1    KZ288254    PBC30766.1    GANO01002704    JAB57167.1    NEVH01006723    PNF37073.1    LBMM01000143    KMR04775.1    GL449088    EFN83279.1    KQ977636    KYN01141.1    KQ980924    KYN11410.1    GECU01021099    GECU01019155    GECU01015687    JAS86607.1    JAS88551.1    JAS92019.1    AJVK01019382    AJVK01019383    AJVK01019384    AJVK01019385    AXCN02002424    CCAG010014882    PYGN01001050    PSN38114.1    JXUM01140972    JXUM01140973    KQ569162    KXJ68744.1    GFDF01003188    JAV10896.1    KQ982268    KYQ58476.1    GL888053    EGI68689.1    ATLV01013581    KE524868    KFB38127.1    GDAI01000283    JAI17320.1    JXJN01017617    ADMH02001606    ETN61841.1    GGFK01008461    MBW41782.1    AXCM01000973    GGFJ01006403    MBW55544.1    AXCP01007318    AJWK01010101    GDHF01004940    JAI47374.1    JRES01001224    KNC24494.1    GAMC01003016    JAC03540.1    KQ971344    EFA05223.1    GGFJ01006814    MBW55955.1    GGFJ01006813    MBW55954.1    KK854082    PTY10882.1    GBXI01011803    JAD02489.1    GBYX01141985    JAO93910.1    NEDP02076724    OWF35492.1    AYCK01020792    NHOQ01001616    PWA23321.1    GEZM01001136    JAV98129.1    GCES01005116    JAR81207.1    CM012439    RVE74919.1   

Proteomes

UP000053240    UP000053268    UP000283053    UP000007151    UP000008820    UP000002320    + More
UP000069940    UP000249989    UP000053105    UP000215335    UP000002358    UP000076502    UP000078541    UP000183832    UP000000311    UP000078540    UP000005205    UP000095301    UP000005203    UP000027135    UP000053825    UP000242457    UP000235965    UP000036403    UP000008237    UP000075885    UP000078542    UP000076408    UP000078492    UP000091820    UP000092462    UP000078200    UP000069272    UP000075886    UP000092444    UP000075884    UP000245037    UP000092445    UP000075809    UP000092443    UP000007755    UP000075900    UP000030765    UP000095300    UP000092460    UP000000673    UP000075920    UP000075883    UP000075880    UP000092461    UP000192223    UP000075901    UP000037069    UP000007266    UP000261400    UP000192224    UP000087266    UP000242188    UP000261480    UP000079169    UP000261500    UP000028760    UP000007635    UP000265080    UP000221080    UP000264840    UP000261420    UP000265040   

Pfam

PF03029   ATP_bind_1        + More
PF14838   INTS5_C

Interpro

IPR004130   Gpn        + More
IPR029444   INTS5_C       
IPR030230   Gpn1/Npa3/XAB1       
IPR027417   P-loop_NTPase       
IPR003593   AAA+_ATPase       

SUPFAM

SSF52540   SSF52540       

ProteinModelPortal

A0A2H1V049   A0A194REB6   A0A194PYG7   A0A3S2L685   A0A212ES60   A0A1E1W6Y9   + More
S4PKV9   Q16TZ7   B0W660   A0A1Q3F4C3   A0A1Q3F4A8   A0A182GD34   A0A0M8ZXM4   A0A232EX19   K7IRL7   A0A154NXX6   A0A195F0K8   A0A0C9RCV1   A0A1J1HH57   E1ZX65   E9IEA5   A0A0T6B659   A0A195BYY8   A0A158P3K0   A0A1I8M785   A0A1B6CA99   A0A088ANI7   A0A067R7P6   A0A0L7R128   A0A1B6G7E8   A0A2A3EHW7   U5EIA7   A0A2J7R8A3   A0A0J7L9Q7   E2BLZ3   A0A182PNV1   A0A151IH85   A0A182YDY3   A0A151IV51   A0A1B6IYN3   A0A1A9W8R4   A0A1B0DQV1   A0A1A9USZ5   A0A182FLY6   A0A182QS09   A0A1B0FHM2   A0A182NP70   A0A2P8Y1P6   A0A182G371   A0A1A9Z6C1   A0A1L8DWV2   A0A151XDL8   A0A1A9XNK6   F4WAT3   A0A182RWX9   A0A084VJI3   A0A0K8TTP7   A0A1I8NY79   A0A1B0BNV4   W5JCN2   A0A2M4AM18   A0A182W7X2   A0A182LYH5   A0A2M4BRB5   A0A182J789   A0A1B0CFG7   A0A1W4X8C9   A0A182SLD7   A0A1W4X747   A0A0K8W8M5   A0A0L0BZ32   W8CCV9   D2A4G3   A0A2M4BS91   A0A2M4BSI3   A0A2R7VTM9   A0A3B5AIY4   A0A1W5ACE9   A0A1W5AKN7   A0A0A1WTT9   A0A1S3RAU2   A0A0S7LWP7   A0A210PG82   A0A3B3Y372   A0A3Q0JGC9   A0A3B3W2H1   A0A087X2N6   G3Q0C1   A0A3P8RL57   A0A2D0RMY4   A0A315VV76   A0A1Y1NK86   G3Q0C4   A0A3Q2X6R5   A0A3B4TU02   A0A147ARZ8   A0A3Q1IXY4   A0A3S2N614  

PDB

5HCN     E-value=7.64655e-80,     Score=756

KEGG

101736249    K06883 uncharacterized protein | (RefSeq) GPN-loop GTPase 1-like

GO

GO:0003924   GO:0005525   GO:0005737   GO:0005634   GO:0016787  

PANTHER

PTHR21231   PTHR21231:SF8  

Subcellular location

Cytoplasm  
Nucleus  

Length:

373

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.41803

Exp number, first 60 AAs:

0.09138

Total prob of N-in:

0.02474

outside

1  -  373

 

 

Pi

2.71193

Theta

18.998912

Tajima's D

-1.605959

CLR

1.326856

CSRT

0.0435978201089946

Interpretation

Uncertain