Gene

KWMTBOMO13396

Pre Gene Modal

BGIBMGA010909

Annotation

PREDICTED:_leucine-rich_repeat-containing_protein_74B-like_[Bombyx_mori]

Location

Bomo_Chr22(-):16120853-16129172      View in EpiBrowser

Full name

Protein CLP1 homolog      

Location in the cell

Nuclear   Reliability : 2.078

CDS

ATGTTCGAACCTCAAATACTTTTTAATTTGAACGGTCAAGATCTTTATTTGGACTTGTGTGAGAAAATGGGCTTGATCCCAGTACGAGGTTTCCACAAAGCTCTCGTTGAAGATGTAATTAATTTACAGTACTACGGTGTTAAACCAGTAGGTGTAAGAGCAATGTGTTTATCATTGACAAACAACAAGTACGTGAAACGCCTCGACTTGTCATACAATCAATTGTCGGAAGACGCTTGTTACCATTTGGGCGAGCTGCTTGGCGACAATTTTAATCTTAAGGAATTGGTATTGACGGGATGCAGGATAGGCACCGAAGGCATACGGAGACTAGTCGTAAGGTTATCGGCGCGAACTATGAAGGAACTGGATTTGTCGAAGAATGAGTTTGGCGAGACGGGCTTTAAATATTTGGCCGATCAGATAGTAAACGGCGCGGTCATTAAAAGATTGAATCTTAGTCACAACGATTTGGGAGAAGAATCGGCCGAAGAATTGGCAGCTGCTTTAGAAAGGAACAACACTATAAAGTGTTTGGATTTGTCTTGGAATCAATTGTTCAGAGGATCAACTGCTTTTATAATAGAGCTGTGTCGGAGCAGGGTGCTCAAGGAATTGAATCTGGCATGGAACGGATTGTTTGTGGGTAGACCTATTTCGTACCTACTAACTGTGCCCACATTGACGACTTTGGATCTTAGTAACAATAAGTTGATTCCGCGAGCGATAAAAGCTATTGCCATCAGACTCAGGCTAGCTAAAAAACTGCACACCCTGAACCTGTCACACAATCCCGTGACTCCTGCAGACGCTTTCCTGCTCCTCAGTAAATTAAGACTTAAAACGGTTGGAATTAAAGTATTGTTACTGGATGGTGTCGGTGTCTCGAAGGAGTTTGTTGACGAACGAAAAGAAGTCTTACAATTGGATTATAGAACCGATACGTCAGTGACCTACGGCCATGTTATACGGAACTACACGTTGTCAAAGCCCGACTTGCGGGCTATTGTTCTTAAGCGAATAGACTTTTTAACAAGCAGATCGTCTAAAAAGAACCAATTGGATATCGGTCTGTACTTCTTACGGGAGTTGAAAACGCGTGAGGCGCCTCACATGATGCCGCGTGAATTAAACAGAGCTATGAGGCAAGCTGGCTTCGTCATGGACGAGGGACTTTTGGACGAGATCGGGAATGCTTTTCCGGGACCACGATTGGAAACCGGAAAGAAAACAATAAATTTACAGAATGTAGCGGATTACATAAAACGTATATGGCCCGAGAAGAAATTTCCACCGACCCCTCCAGAGCCCGAACCAGAACCTAAACGAAAAAAGAAAAAAAAGAGGAAGAAGTATTTTAAGATTAAATGA

Protein

MFEPQILFNLNGQDLYLDLCEKMGLIPVRGFHKALVEDVINLQYYGVKPVGVRAMCLSLTNNKYVKRLDLSYNQLSEDACYHLGELLGDNFNLKELVLTGCRIGTEGIRRLVVRLSARTMKELDLSKNEFGETGFKYLADQIVNGAVIKRLNLSHNDLGEESAEELAAALERNNTIKCLDLSWNQLFRGSTAFIIELCRSRVLKELNLAWNGLFVGRPISYLLTVPTLTTLDLSNNKLIPRAIKAIAIRLRLAKKLHTLNLSHNPVTPADAFLLLSKLRLKTVGIKVLLLDGVGVSKEFVDERKEVLQLDYRTDTSVTYGHVIRNYTLSKPDLRAIVLKRIDFLTSRSSKKNQLDIGLYFLRELKTREAPHMMPRELNRAMRQAGFVMDEGLLDEIGNAFPGPRLETGKKTINLQNVADYIKRIWPEKKFPPTPPEPEPEPKRKKKKKRKKYFKIK

Description

Required for endonucleolytic cleavage during polyadenylation-dependent pre-mRNA 3'-end formation.

Similarity

Belongs to the Clp1 family. Clp1 subfamily.

Uniprot

H9JN06   A0A212FAK7   H9JAV4   A0A0L7LSM5   A0A212F1N8   A0A194QJ93   + More
A0A1C9EGH4   H9JB25   A0A194RMP2   A0A194QND4   A0A0L7LTB1   A0A2H1WGQ1   A0A2H1W1H8   A0A2H1WXC4   A0A194QHL3   A0A194RNL2   E2BHS2   A0A1B6ETI4   A0A026W7F1   A0A139WEM6   A0A195CMP5   A0A151XCR4   A0A1B6KJN2   A0A151JC12   A0A0M9A4E4   N6SZA8   A0A0L7QMC8   A0A151I302   A0A088AB53   U4URG0   A0A195F9T4   A0A2A3EPX5   A0A1Y1L9F8   F4WYU4   K1RUX3   A0A1U8CZ56   A0A1S3K5K9   A0A1S3J7G8   A0A151MLE8   W5L4F3   A0A232EGL8   G1KTJ7   G1KVY3   H3B3F3   V9KUN0   M3XJM7   K1PZ51   R7U8R8   A0A3B4URC1  

Pubmed

19121390    22118469    26227816    26354079    20798317    24508170    + More
18362917    19820115    23537049    28004739    21719571    22992520    22293439    25329095    28648823    9215903    24402279    23254933   

EMBL

BABH01041387    AGBW02009461    OWR50759.1    BABH01008368    JTDY01000167    KOB78478.1    + More
AGBW02010841    OWR47646.1    KQ458793    KPJ04995.1    KX778609    AON96589.1    BABH01008501    KQ459984    KPJ19098.1    KPJ04996.1    KOB78481.1    ODYU01008523    SOQ52197.1    ODYU01005735    SOQ46887.1    ODYU01011363    SOQ57064.1    KPJ04997.1    KPJ19097.1    GL448324    EFN84755.1    GECZ01028464    JAS41305.1    KK107429    EZA50959.1    KQ971354    KYB26428.1    KQ977565    KYN01950.1    KQ982298    KYQ58153.1    GEBQ01028314    JAT11663.1    KQ979120    KYN22568.1    KQ435736    KOX77005.1    APGK01051086    APGK01051087    KB741181    ENN73089.1    KQ414894    KOC59686.1    KQ976508    KYM82782.1    KB632333    ERL92741.1    KQ981727    KYN37193.1    KZ288194    PBC33815.1    GEZM01066689    JAV67727.1    GL888463    EGI60598.1    JH817779    EKC38526.1    AKHW03005800    KYO25378.1    NNAY01004742    OXU17483.1    AFYH01003060    AFYH01003061    JW869754    AFP02272.1    JH815972    EKC21830.1    AMQN01001943    KB306824    ELT99510.1   

Proteomes

UP000005204    UP000007151    UP000037510    UP000053268    UP000053240    UP000008237    + More
UP000053097    UP000007266    UP000078542    UP000075809    UP000078492    UP000053105    UP000019118    UP000053825    UP000078540    UP000005203    UP000030742    UP000078541    UP000242457    UP000007755    UP000005408    UP000189705    UP000085678    UP000050525    UP000018467    UP000215335    UP000001646    UP000008672    UP000014760    UP000261420   

PRIDE

H9JN06    H9JAV4    H9JB25   

Pfam

PF13516   LRR_6        + More
PF00560   LRR_1
PF16575   CLP1_P
PF06807   Clp1
PF16573   CLP1_N
PF13499   EF-hand_7

Interpro

IPR001611   Leu-rich_rpt        + More
IPR032675   LRR_dom_sf       
IPR006553   Leu-rich_rpt_Cys-con_subtyp       
IPR032324   Clp1_N       
IPR027417   P-loop_NTPase       
IPR038238   Clp1_C_sf       
IPR038239   Clp1_N_sf       
IPR032319   CLP1_P       
IPR010655   Clp1_C       
IPR028606   Clp1       
IPR011992   EF-hand-dom_pair       
IPR002048   EF_hand_dom       
IPR018247   EF_Hand_1_Ca_BS       

SUPFAM

SSF52540   SSF52540        + More
SSF47473   SSF47473       

Gene 3D

3.80.10.10     2.60.120.1030     3.30.70.2410    

CDD

cd00051  EFh

ProteinModelPortal

H9JN06   A0A212FAK7   H9JAV4   A0A0L7LSM5   A0A212F1N8   A0A194QJ93   + More
A0A1C9EGH4   H9JB25   A0A194RMP2   A0A194QND4   A0A0L7LTB1   A0A2H1WGQ1   A0A2H1W1H8   A0A2H1WXC4   A0A194QHL3   A0A194RNL2   E2BHS2   A0A1B6ETI4   A0A026W7F1   A0A139WEM6   A0A195CMP5   A0A151XCR4   A0A1B6KJN2   A0A151JC12   A0A0M9A4E4   N6SZA8   A0A0L7QMC8   A0A151I302   A0A088AB53   U4URG0   A0A195F9T4   A0A2A3EPX5   A0A1Y1L9F8   F4WYU4   K1RUX3   A0A1U8CZ56   A0A1S3K5K9   A0A1S3J7G8   A0A151MLE8   W5L4F3   A0A232EGL8   G1KTJ7   G1KVY3   H3B3F3   V9KUN0   M3XJM7   K1PZ51   R7U8R8   A0A3B4URC1  

PDB

4R6G     E-value=1.13187e-06,     Score=126

KEGG

105841854    no KO assigned | (RefSeq) leucine-rich repeat-containing protein 74B-like

GO

GO:0005849   GO:0006378   GO:0005634   GO:0006388   GO:0005524   GO:0005509   GO:0005515   GO:0008270   GO:0007018   GO:0008017   GO:0005525   GO:0031386   GO:0048869   GO:0003676   GO:0016491   GO:0015930  

Subcellular location

Nucleus  

Length:

456

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.0426900000000001

Exp number, first 60 AAs:

0.00103

Total prob of N-in:

0.00238

outside

1  -  456

 

 

Pi

31.036106

Theta

23.949363

Tajima's D

0.871672

CLR

0.460592

CSRT

0.630518474076296

Interpretation

Uncertain