Gene

KWMTBOMO13395

Pre Gene Modal

BGIBMGA010910

Annotation

PREDICTED:_proton-coupled_folate_transporter-like_[Bombyx_mori]

Location

Bomo_Chr22(-):16082651-16083658      View in EpiBrowser

Full name

Angiotensin-converting enzyme      

Location in the cell

PlasmaMembrane   Reliability : 4.673

CDS

ATGATTGATTGGACTTTAACTGTTGAACAACAGCCTAACGTGATGAATGGAATAAACGCATCCGCTGGGAAACCGGCGGCCGTGGAAACGGGGAAAGACGAAGCGAAAATTAAAAGGTCCGGCGTCAGAGAGAAATTGATGCAGATCAGATCGAACATTACGGTGGAACCGATTATTGCGTGTTACATTATGTCTAATGTGTTCTCGGGACTTGCAGTGCAAAATCTGAATTTAGAGAAGGCGTGCCGAGTGAACTTGGGTTATAGCGATGAAGTGTGTTCGGCACTGAAGAGACGGCAGACTGAGAATTACACGATGGAGGAAGCAGAGGTCCAGAAACTAACGGCATCCGTGCAAGCGTGGAAGAATATTGTACAAACAGCATTTCCGTGCATTCTCGTGTTATTTGTAGGCTCTTGGAGTGACAAGACTGGAAAGAGAAAAGCGTGCATATTACTCCCGATCGTAGGGGAAGTACTCTGTTGTACTAGTTTTATTTTGAACACGTATTTCTTCTATGAATTACCGTTGGAGATAACGGCCCTATCGGATTTATTTCCGTCATTAACAGGAGGCTGGATAACTGTGTGCGTCGGTGTGTTCAGCTACATTGGAGATGTGACTACGAAAGAAATGAGGACATTCAGGGTGGGCGTGGCGAATCTCTGCATGTCCCTGGGGATTCCGCTCGGTATGTCCCTGAGCGGTATACTACTCCAGAAGATTGGTTACTACGGGATATTTTTGATATCGAATTTTCTGTATTTGACCAGTTTCATTTACGGCTGCATTCGGTTAAAAGATCCCGTAATATCGGAAGGGAGGCACACGGTGAGTTCATGTTCAAATTAG

Protein

MIDWTLTVEQQPNVMNGINASAGKPAAVETGKDEAKIKRSGVREKLMQIRSNITVEPIIACYIMSNVFSGLAVQNLNLEKACRVNLGYSDEVCSALKRRQTENYTMEEAEVQKLTASVQAWKNIVQTAFPCILVLFVGSWSDKTGKRKACILLPIVGEVLCCTSFILNTYFFYELPLEITALSDLFPSLTGGWITVCVGVFSYIGDVTTKEMRTFRVGVANLCMSLGIPLGMSLSGILLQKIGYYGIFLISNFLYLTSFIYGCIRLKDPVISEGRHTVSSCSN

Cofactor

Zn(2+)

Similarity

Belongs to the peptidase M2 family.
Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.

Uniprot

H9JN07   A0A2H1WVH5   A0A2A4IY18   A0A0L7KUI5   A0A194REM1   A0A212FAK5   + More
A0A194PXM6   A0A212FAJ8   H9JN35   A0A3S2PBF1   A0A194PXP8   A0A194RE89   A0A2H1WT47   A0A2A4J5Y1   A0A2P8YGX7   A0A2J7PUB6   N6U6S7   A0A182J2E5   Q5TSW5   A0A182QCE8   A0A067RJA9   A0A2C9H8S5   B3N1F7   A0A182MSS2   A0A0L7LL21   A0A182U4U1   A0A2H1W9L1   A0A1Y1KH29   A0A2M4CUE7   A0A2M4CSN5   A0A2M4CTY3   A0A2M4BIX1   A0A2M4BIV5   A0A2M4CUE3   A0A0L7LPQ8   A0A2M3Z363   A0A2M3Z330   A0A182VHT3   A0A2R7WWJ8   A0A2M4AAV7   U4URR0   Q16W79   Q6NPA2   Q9VY22   A0A3B0K378   B4L4F7   A0A0K8WKB4   A0A2A4IW55   B4R4V6   B4JJN3   A0A026WMI6   A0A194PZD1   A0A0A1XR69   A0A1W4VHL4   B4PW63   A0A1B6CY04   A0A2A4ISH2   B4GY42   A0A0L7L9Z5   W8C3P0   A0A194RF29   Q29H91   A0A034W601   B4M2P7   D2A535   B0WAI1   A0A194RDI4   A0A2A4J4Z4   A0A194PXN1   A0A1Q3FLB8   A0A1Q3FLC7   B3NUZ2   A0A0M4FAI8   A0A1I8M3Q0   B4NPQ3   A0A1L8DDP9   A0A224XHS1   H9JN31   E2A659   H9JAJ5   A0A195CVZ7   A0A194QSS2   A0A182F8Z6   T1HEN2   A0A154PAY0   A0A182N9U1   E2BSZ7   A0A1I8PUY1   A0A158NYI1   A0A195F6C4   A0A151ITA2   A0A1J1HPT6   A0A182RDY9   A0A1W4WW74   A0A1B0CBZ1   A0A3S2LGU6   A0A182PQS5   A0A084WT83   A0A1B6IHD1   A0A1A9XH14  

EC Number

3.4.-.-

Pubmed

19121390    26227816    26354079    22118469    29403074    23537049    + More
12364791    14747013    17210077    24845553    17994087    28004739    17510324    10731132    12537568    12537572    12537573    12537574    16110336    17569856    17569867    26109357    26109356    24508170    30249741    25830018    17550304    24495485    15632085    25348373    18362917    19820115    25315136    20798317    21347285    24438588   

EMBL

BABH01041390    BABH01041391    BABH01041392    ODYU01011363    SOQ57061.1    NWSH01004603    + More
PCG64857.1    JTDY01005733    KOB66684.1    KQ460323    KPJ15909.1    AGBW02009461    OWR50760.1    KQ459586    KPI98096.1    OWR50762.1    BABH01030450    RSAL01000124    RVE46608.1    KPI98097.1    KPJ15907.1    ODYU01010862    SOQ56230.1    NWSH01002984    PCG67146.1    PYGN01000603    PSN43505.1    NEVH01021203    PNF19923.1    APGK01040551    KB740983    ENN76351.1    AAAB01008898    EAL40562.4    AXCN02001200    KK852651    KDR19441.1    CH902654    EDV33596.1    AXCM01000458    JTDY01000713    KOB76125.1    ODYU01007183    SOQ49737.1    GEZM01088643    GEZM01088642    JAV58047.1    GGFL01004789    MBW68967.1    GGFL01004111    MBW68289.1    GGFL01004110    MBW68288.1    GGFJ01003792    MBW52933.1    GGFJ01003793    MBW52934.1    GGFL01004788    MBW68966.1    JTDY01000388    KOB77422.1    GGFM01002194    MBW22945.1    GGFM01002176    MBW22927.1    KK855798    PTY23912.1    GGFK01004578    MBW37899.1    KB632410    ERL95208.1    CH477573    EAT38831.1    BT011024    AAR30184.1    AE014298    BT133123    AAF48383.1    AEY64291.1    OUUW01000015    SPP88717.1    CH933810    EDW07435.1    GDHF01032155    GDHF01019937    GDHF01013697    GDHF01000723    JAI20159.1    JAI32377.1    JAI38617.1    JAI51591.1    NWSH01006054    PCG63706.1    CM000366    EDX17913.1    CH916370    EDV99785.1    KK107151    QOIP01000003    EZA57287.1    RLU24717.1    KPI98099.1    GBXI01016992    GBXI01013508    GBXI01006853    GBXI01003332    GBXI01000927    JAC97299.1    JAD00784.1    JAD07439.1    JAD10960.1    JAD13365.1    CM000162    EDX01694.1    KRK06299.1    GEDC01018946    GEDC01008979    JAS18352.1    JAS28319.1    NWSH01007506    PCG62937.1    CH479196    EDW27669.1    JTDY01002065    KOB72195.1    GAMC01005989    JAC00567.1    KPJ15905.1    CH379064    EAL31867.2    GAKP01009377    JAC49575.1    CH940651    EDW65951.1    KQ971361    EFA05308.1    DS231872    EDS41404.1    KPJ15903.1    NWSH01002978    PCG67155.1    KPI98101.1    GFDL01006678    JAV28367.1    GFDL01006731    JAV28314.1    CH954180    EDV47090.1    CP012528    ALC49420.1    CH964291    EDW86493.1    GFDF01009508    JAV04576.1    GFTR01004389    JAW12037.1    BABH01030471    GL437108    EFN71118.1    BABH01009475    BABH01009476    BABH01009477    KQ977220    KYN04851.1    KQ461155    KPJ08369.1    ACPB03012810    KQ434864    KZC08967.1    GL450313    EFN81185.1    ADTU01003883    KQ981768    KYN35936.1    KQ981029    KYN10190.1    CVRI01000006    CRK88225.1    AJWK01006000    AJWK01006001    RSAL01000011    RVE53552.1    ATLV01026865    ATLV01026866    KE525420    KFB53427.1    GECU01021378    JAS86328.1   

Proteomes

UP000005204    UP000218220    UP000037510    UP000053240    UP000007151    UP000053268    + More
UP000283053    UP000245037    UP000235965    UP000019118    UP000075880    UP000007062    UP000075886    UP000027135    UP000076407    UP000007801    UP000075883    UP000075902    UP000075903    UP000030742    UP000008820    UP000000803    UP000268350    UP000009192    UP000000304    UP000001070    UP000053097    UP000279307    UP000192221    UP000002282    UP000008744    UP000001819    UP000008792    UP000007266    UP000002320    UP000008711    UP000092553    UP000095301    UP000007798    UP000000311    UP000078542    UP000069272    UP000015103    UP000076502    UP000075884    UP000008237    UP000095300    UP000005205    UP000078541    UP000078492    UP000183832    UP000075900    UP000192223    UP000092461    UP000075885    UP000030765    UP000092443   

PRIDE

H9JN07    H9JN35    Q6NPA2    Q9VY22    H9JN31    H9JAJ5    + More

Pfam

PF07690   MFS_1        + More
PF01401   Peptidase_M2
PF07701   HNOBA
PF00211   Guanylate_cyc
PF07700   HNOB

Interpro

IPR020846   MFS_dom        + More
IPR011701   MFS       
IPR036259   MFS_trans_sf       
IPR001548   Peptidase_M2       
IPR018297   A/G_cyclase_CS       
IPR038158   H-NOX_domain_sf       
IPR024096   NO_sig/Golgi_transp_ligand-bd       
IPR011645   HNOB_dom_associated       
IPR029787   Nucleotide_cyclase       
IPR001054   A/G_cyclase       
IPR011644   Heme_NO-bd       

SUPFAM

SSF103473   SSF103473        + More
SSF55073   SSF55073       
SSF111126   SSF111126       

Gene 3D

3.30.70.1230     3.90.1520.10    

CDD

cd06174  MFS
cd06461  M2_ACE

ProteinModelPortal

H9JN07   A0A2H1WVH5   A0A2A4IY18   A0A0L7KUI5   A0A194REM1   A0A212FAK5   + More
A0A194PXM6   A0A212FAJ8   H9JN35   A0A3S2PBF1   A0A194PXP8   A0A194RE89   A0A2H1WT47   A0A2A4J5Y1   A0A2P8YGX7   A0A2J7PUB6   N6U6S7   A0A182J2E5   Q5TSW5   A0A182QCE8   A0A067RJA9   A0A2C9H8S5   B3N1F7   A0A182MSS2   A0A0L7LL21   A0A182U4U1   A0A2H1W9L1   A0A1Y1KH29   A0A2M4CUE7   A0A2M4CSN5   A0A2M4CTY3   A0A2M4BIX1   A0A2M4BIV5   A0A2M4CUE3   A0A0L7LPQ8   A0A2M3Z363   A0A2M3Z330   A0A182VHT3   A0A2R7WWJ8   A0A2M4AAV7   U4URR0   Q16W79   Q6NPA2   Q9VY22   A0A3B0K378   B4L4F7   A0A0K8WKB4   A0A2A4IW55   B4R4V6   B4JJN3   A0A026WMI6   A0A194PZD1   A0A0A1XR69   A0A1W4VHL4   B4PW63   A0A1B6CY04   A0A2A4ISH2   B4GY42   A0A0L7L9Z5   W8C3P0   A0A194RF29   Q29H91   A0A034W601   B4M2P7   D2A535   B0WAI1   A0A194RDI4   A0A2A4J4Z4   A0A194PXN1   A0A1Q3FLB8   A0A1Q3FLC7   B3NUZ2   A0A0M4FAI8   A0A1I8M3Q0   B4NPQ3   A0A1L8DDP9   A0A224XHS1   H9JN31   E2A659   H9JAJ5   A0A195CVZ7   A0A194QSS2   A0A182F8Z6   T1HEN2   A0A154PAY0   A0A182N9U1   E2BSZ7   A0A1I8PUY1   A0A158NYI1   A0A195F6C4   A0A151ITA2   A0A1J1HPT6   A0A182RDY9   A0A1W4WW74   A0A1B0CBZ1   A0A3S2LGU6   A0A182PQS5   A0A084WT83   A0A1B6IHD1   A0A1A9XH14  

KEGG

101742596    K20840 MFS transporter, PCFT/HCP family, solute carrier family 46, member 3 | (RefSeq) proton-couple

GO

GO:0055085   GO:0016021   GO:0004180   GO:0008237   GO:0008241   GO:0046872   GO:0020037   GO:0000166   GO:0035556   GO:0004383   GO:0008270   GO:0007018   GO:0008017   GO:0005525   GO:0031386   GO:0048869   GO:0003676   GO:0016491   GO:0015930  

PANTHER

PTHR10514  

Length:

283

Number of predicted TMHs:

4

Exp number of AAs in TMHs:

111.07504

Exp number, first 60 AAs:

4.86148

Total prob of N-in:

0.75512

inside

1  -  149

TMhelix

150  -  172

outside

173  -  181

TMhelix

182  -  204

inside

205  -  216

TMhelix

217  -  239

outside

240  -  243

TMhelix

244  -  266

inside

267  -  283

 

 

Pi

18.195567

Theta

13.327495

Tajima's D

1.007883

CLR

1.535876

CSRT

0.672966351682416

Interpretation

Uncertain