Gene

KWMTBOMO13393

Pre Gene Modal

BGIBMGA010910

Annotation

PREDICTED:_proton-coupled_folate_transporter-like_[Bombyx_mori]

Location

Bomo_Chr22(-):16071672-16074668      View in EpiBrowser

Full name

Angiotensin-converting enzyme      

Location in the cell

PlasmaMembrane   Reliability : 3.799

CDS

ATGAATGTTTTGTATTTATTCATGAGGTACAGATTTAATTGGGACGAGGTACAATTCAGTATGTTCTGCACGTATAGCATCATCACCAATTTAGTGGGTACATTGTTCTCAATCAGCATATTCAGTGACTTCATGAAGCTGGACGACACTGTAGTGGGCATCATCTCTTGCACTAGCAAGATCTTCGCGTCTCTGGTCTTCGCTTTCGCCACGACCACTGCTGAGATTTACATAGCTCCATTGGTAGAGATATTCAATGGTACATCGTTCATCGCAATGCGCTCAATAGCGTCAAAGTTAGTGACGAGTGAGGAGCTGGGTGAGTGA

Protein

MNVLYLFMRYRFNWDEVQFSMFCTYSIITNLVGTLFSISIFSDFMKLDDTVVGIISCTSKIFASLVFAFATTTAEIYIAPLVEIFNGTSFIAMRSIASKLVTSEELGE

Cofactor

Zn(2+)

Similarity

Belongs to the peptidase M2 family.
Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.

Uniprot

A0A2H1X2C4   H9JN07   A0A2A4IY18   A0A194REM1   A0A212FAK5   A0A194PXM6   + More
A0A0L7KYV3   S4PJ57   A0A2J7PUC7   A0A194QS69   A0A194PXP8   A0A194RE89   A0A1E1W1C8   A0A2H1W938   A0A212EJ99   A0A2W1BZD6   A0A2S2NH85   A0A2P8YGX5   A0A212FAJ8   A0A194QAI0   A0A3S2LGU6   A0A0K8SJM1   H9JAJ5   A0A3S2PBF1   A0A067RJA9   A0A0A9WCX6   A0A2H1W9V5   A0A069DVE7   A0A2S2PZG0   A0A023F3V3   A0A1B6LYH9   A0A026WMI6   A0A182PQS5   A0A146LMI6   A0A1B0DCV1   A0A1B6CY04   A0A182RDY9   A0A182W3L5   J9KB87   A0A1L8DE03   A0A2H8TM94   A0A182VHT3   A0A2C9H8S5   Q5TSW5   A0A182N9U1   E2A659   A0A195F6C4   A0A151ITA2   F4WT02   A0A158NYI1   A0A195AZB4   A0A195CVZ7   A0A151WHP4   A0A182K2U1   K7J2K2   A0A2M4CSN5   E9IUT7   A0A2M4CUE3   A0A2M4CUE7   A0A1L8DDP9   A0A2M3Z363   A0A182MSS2   A0A2M4BIV5   A0A2M4CTY3   A0A2M3Z330   A0A2M4BIX1   A0A084WT83   A0A182J2E5   A0A2M4AAV7   A0A182QCE8   E2BSZ7   A0A1B6HTG8   A0A1Q3FKN7   A0A1Q3FL61   A0A2A4JD86   A0A182H1C2   A0A1Q3FLC7   A0A1J1HPT6   B0WAI1   A0A1Q3FLB8   Q16W79   A0A1B6GHB7   T1PHH7   A0A2H8THB2   A0A3S2LH66   A0A2S2NZI4   U4URR0   X1WUT6   A0A0L7RGJ1   D2A535   A0A1B0FMN2   A0A154PAY0   A0A1A9ZI85   A0A1A9XH14   A0A1A9VRP7   A0A1Y1KF48   A0A1A9WCM0   A0A1B0ANC8   A0A1I8M3Q0   J9KB15  

EC Number

3.4.-.-

Pubmed

19121390    26354079    22118469    26227816    23622113    28756777    + More
29403074    24845553    25401762    26334808    25474469    24508170    30249741    26823975    12364791    14747013    17210077    20798317    21719571    21347285    20075255    21282665    24438588    26483478    17510324    23537049    18362917    19820115    28004739    25315136   

EMBL

ODYU01012927    SOQ59469.1    BABH01041390    BABH01041391    BABH01041392    NWSH01004603    + More
PCG64857.1    KQ460323    KPJ15909.1    AGBW02009461    OWR50760.1    KQ459586    KPI98096.1    JTDY01004210    KOB68453.1    GAIX01002757    JAA89803.1    NEVH01021203    PNF19928.1    KQ461155    KPJ08368.1    KPI98097.1    KPJ15907.1    GDQN01010353    JAT80701.1    ODYU01007104    SOQ49580.1    AGBW02014503    OWR41557.1    KZ149899    PZC78617.1    GGMR01003880    MBY16499.1    PYGN01000603    PSN43506.1    OWR50762.1    KQ459249    KPJ02439.1    RSAL01000011    RVE53552.1    GBRD01012475    GBRD01012473    JAG53349.1    BABH01009475    BABH01009476    BABH01009477    RSAL01000124    RVE46608.1    KK852651    KDR19441.1    GBHO01038000    JAG05604.1    ODYU01007183    SOQ49736.1    GBGD01001034    JAC87855.1    GGMS01001703    MBY70906.1    GBBI01002626    JAC16086.1    GEBQ01011235    JAT28742.1    KK107151    QOIP01000003    EZA57287.1    RLU24717.1    GDHC01010234    JAQ08395.1    AJVK01031396    GEDC01018946    GEDC01008979    JAS18352.1    JAS28319.1    ABLF02035671    GFDF01009514    JAV04570.1    GFXV01003482    MBW15287.1    AAAB01008898    EAL40562.4    GL437108    EFN71118.1    KQ981768    KYN35936.1    KQ981029    KYN10190.1    GL888331    EGI62615.1    ADTU01003883    KQ976701    KYM77299.1    KQ977220    KYN04851.1    KQ983114    KYQ47337.1    GGFL01004111    MBW68289.1    GL766050    EFZ15659.1    GGFL01004788    MBW68966.1    GGFL01004789    MBW68967.1    GFDF01009508    JAV04576.1    GGFM01002194    MBW22945.1    AXCM01000458    GGFJ01003793    MBW52934.1    GGFL01004110    MBW68288.1    GGFM01002176    MBW22927.1    GGFJ01003792    MBW52933.1    ATLV01026865    ATLV01026866    KE525420    KFB53427.1    GGFK01004578    MBW37899.1    AXCN02001200    GL450313    EFN81185.1    GECU01029729    JAS77977.1    GFDL01006875    JAV28170.1    GFDL01006801    JAV28244.1    NWSH01001989    PCG69504.1    JXUM01102960    KQ564767    KXJ71770.1    GFDL01006731    JAV28314.1    CVRI01000006    CRK88225.1    DS231872    EDS41404.1    GFDL01006678    JAV28367.1    CH477573    EAT38831.1    GECZ01007935    JAS61834.1    KA648277    AFP62906.1    GFXV01001690    MBW13495.1    RVE46607.1    GGMR01009853    MBY22472.1    KB632410    ERL95208.1    ABLF02027884    KQ414596    KOC69980.1    KQ971361    EFA05308.1    CCAG010001068    KQ434864    KZC08967.1    GEZM01088644    JAV58046.1    JXJN01000793    ABLF02027891    ABLF02027892   

Proteomes

UP000005204    UP000218220    UP000053240    UP000007151    UP000053268    UP000037510    + More
UP000235965    UP000245037    UP000283053    UP000027135    UP000053097    UP000279307    UP000075885    UP000092462    UP000075900    UP000075920    UP000007819    UP000075903    UP000076407    UP000007062    UP000075884    UP000000311    UP000078541    UP000078492    UP000007755    UP000005205    UP000078540    UP000078542    UP000075809    UP000075881    UP000002358    UP000075883    UP000030765    UP000075880    UP000075886    UP000008237    UP000069940    UP000249989    UP000183832    UP000002320    UP000008820    UP000030742    UP000053825    UP000007266    UP000092444    UP000076502    UP000092445    UP000092443    UP000078200    UP000091820    UP000092460    UP000095301   

PRIDE

H9JN07    H9JAJ5   

Pfam

PF07690   MFS_1        + More
PF01401   Peptidase_M2
PF07701   HNOBA
PF00211   Guanylate_cyc
PF07700   HNOB

Interpro

IPR036259   MFS_trans_sf        + More
IPR020846   MFS_dom       
IPR011701   MFS       
IPR001548   Peptidase_M2       
IPR018297   A/G_cyclase_CS       
IPR038158   H-NOX_domain_sf       
IPR024096   NO_sig/Golgi_transp_ligand-bd       
IPR011645   HNOB_dom_associated       
IPR029787   Nucleotide_cyclase       
IPR001054   A/G_cyclase       
IPR011644   Heme_NO-bd       

SUPFAM

SSF103473   SSF103473        + More
SSF55073   SSF55073       
SSF111126   SSF111126       

Gene 3D

3.30.70.1230     3.90.1520.10    

CDD

cd06174  MFS
cd06461  M2_ACE

ProteinModelPortal

A0A2H1X2C4   H9JN07   A0A2A4IY18   A0A194REM1   A0A212FAK5   A0A194PXM6   + More
A0A0L7KYV3   S4PJ57   A0A2J7PUC7   A0A194QS69   A0A194PXP8   A0A194RE89   A0A1E1W1C8   A0A2H1W938   A0A212EJ99   A0A2W1BZD6   A0A2S2NH85   A0A2P8YGX5   A0A212FAJ8   A0A194QAI0   A0A3S2LGU6   A0A0K8SJM1   H9JAJ5   A0A3S2PBF1   A0A067RJA9   A0A0A9WCX6   A0A2H1W9V5   A0A069DVE7   A0A2S2PZG0   A0A023F3V3   A0A1B6LYH9   A0A026WMI6   A0A182PQS5   A0A146LMI6   A0A1B0DCV1   A0A1B6CY04   A0A182RDY9   A0A182W3L5   J9KB87   A0A1L8DE03   A0A2H8TM94   A0A182VHT3   A0A2C9H8S5   Q5TSW5   A0A182N9U1   E2A659   A0A195F6C4   A0A151ITA2   F4WT02   A0A158NYI1   A0A195AZB4   A0A195CVZ7   A0A151WHP4   A0A182K2U1   K7J2K2   A0A2M4CSN5   E9IUT7   A0A2M4CUE3   A0A2M4CUE7   A0A1L8DDP9   A0A2M3Z363   A0A182MSS2   A0A2M4BIV5   A0A2M4CTY3   A0A2M3Z330   A0A2M4BIX1   A0A084WT83   A0A182J2E5   A0A2M4AAV7   A0A182QCE8   E2BSZ7   A0A1B6HTG8   A0A1Q3FKN7   A0A1Q3FL61   A0A2A4JD86   A0A182H1C2   A0A1Q3FLC7   A0A1J1HPT6   B0WAI1   A0A1Q3FLB8   Q16W79   A0A1B6GHB7   T1PHH7   A0A2H8THB2   A0A3S2LH66   A0A2S2NZI4   U4URR0   X1WUT6   A0A0L7RGJ1   D2A535   A0A1B0FMN2   A0A154PAY0   A0A1A9ZI85   A0A1A9XH14   A0A1A9VRP7   A0A1Y1KF48   A0A1A9WCM0   A0A1B0ANC8   A0A1I8M3Q0   J9KB15  

KEGG

101742596    K20840 MFS transporter, PCFT/HCP family, solute carrier family 46, member 3 | (RefSeq) proton-couple

GO

GO:0016021   GO:0055085   GO:0008241   GO:0046872   GO:0004180   GO:0008237   GO:0020037   GO:0000166   GO:0035556   GO:0004383  

PANTHER

PTHR10514  

Length:

108

Number of predicted TMHs:

2

Exp number of AAs in TMHs:

47.59278

Exp number, first 60 AAs:

27.49254

Total prob of N-in:

0.85703

POSSIBLE N-term signal

sequence

inside

1  -  18

TMhelix

19  -  41

outside

42  -  50

TMhelix

51  -  70

inside

71  -  108

 

 

Pi

20.589651

Theta

19.365735

Tajima's D

0.079265

CLR

2.990873

CSRT

0.396930153492325

Interpretation

Uncertain