Gene

KWMTBOMO13391

Pre Gene Modal

BGIBMGA010938

Annotation

PREDICTED:_proton-coupled_folate_transporter-like_[Papilio_machaon]

Location

Bomo_Chr22(-):15999666-16009388      View in EpiBrowser

Full name

Angiotensin-converting enzyme      

Location in the cell

PlasmaMembrane   Reliability : 4.212

CDS

ATGGGAGCTTTCGTATACGCTTTCGCCAGGAACAACTTGGAGATATATATCGCTCCGTTGATGGAAATTTTAAATGGAACATCATTCATAGCGATGCGATCGATCGCAACGAAACTGGTGAGCGGGGAGGAATTTGGCAAGGTGAATTCTTTGTTCGGTCTGGCGGAGGCGATGATGCCGCTGGTTTACGGACCTCTCTACTCCCGCGTCTACATGGCGACGCTCAACGTGCTGCCAGGCGCTGTCTTCCTGCTCGGAGCCAGTTTGACTTTACCTGCTATTTTCATATTTGGGTGGTTGTATTTTGAACATAAAAAAGACGCACAGAGGAAAGTAAACACAACATGTGATTCGGAAAAATAA

Protein

MGAFVYAFARNNLEIYIAPLMEILNGTSFIAMRSIATKLVSGEEFGKVNSLFGLAEAMMPLVYGPLYSRVYMATLNVLPGAVFLLGASLTLPAIFIFGWLYFEHKKDAQRKVNTTCDSEK

Cofactor

Zn(2+)

Similarity

Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
Belongs to the peptidase M2 family.

Uniprot

A0A194RE89   A0A194PXP8   A0A3S2PBF1   A0A212FAJ8   A0A212FAK5   A0A194REM1   + More
A0A2H1X2C4   A0A2P8YGX5   A0A3S2LH66   A0A1B6GHB7   A0A2A4JD86   A0A1B6HTG8   A0A2A4IY18   A0A194PXM6   A0A1B6CY04   D2A535   A0A2S2NH85   A0A1B6LYH9   A0A0J7KQN9   A0A1J1HPT6   A0A0K8SJM1   A0A154PAY0   A0A1W4WW74   A0A1Y1KF48   A0A0A9WCX6   A0A2H1WT49   A0A0T6BFY6   A0A2S2PZG0   A0A146LMI6   A0A023F3V3   A0A069DVE7   A0A194QS69   A0A1E1W1C8   A0A2M4AAV7   A0A2M4CTY3   A0A2M4CUE7   A0A2M4BIX1   A0A2M4CSN5   A0A2M4BIV5   A0A2M4CUE3   A0A212FAL1   J9KB87   A0A2H8TM94   Q16W79   A0A2M3Z330   A0A2M3Z363   U4URR0   A0A1Q3FL61   A0A1Q3FKN7   B0WAI1   E2BSZ7   A0A1Q3FLC7   A0A1Q3FLB8   A0A182QCE8   A0A026WMI6   A0A2A4IXD4   A0A182J2E5   A0A0K8VHS8   A0A2R7W706   A0A1L8DE03   A0A182MSS2   A0A182VHT3   A0A2C9H8S5   A0A1Y1KH29   Q5TSW5   A0A1L8DDP9   F4WT02   A0A151ITA2   A0A158NYI1   A0A195AZB4   A0A151WHP4   E2A659   A0A195CVZ7   A0A195F6C4   A0A3S2LGU6   A0A0L7RGJ1   A0A182H1C2   A0A2S2NPL3   A0A084WT83   A0A182N9U1   E9IUT7   A0A194QAI0   H9JAJ5   A0A0M8ZQJ4   A0A212EJ99   A0A182K2U1   A0A2J7PUC7   A0A194RIY8   A0A2H8THB2   A0A182RDY9   A0A182PQS5   A0A182W3L5   A0A0K8WKB4   A0A2W1BZD6   A0A088ANF5   A0A2A3EDD3   D6WRR1   A0A034W601   A0A194PYJ5  

EC Number

3.4.-.-

Pubmed

26354079    22118469    29403074    18362917    19820115    28004739    + More
25401762    26823975    25474469    26334808    17510324    23537049    20798317    24508170    30249741    12364791    14747013    17210077    21719571    21347285    26483478    24438588    21282665    19121390    28756777    25348373   

EMBL

KQ460323    KPJ15907.1    KQ459586    KPI98097.1    RSAL01000124    RVE46608.1    + More
AGBW02009461    OWR50762.1    OWR50760.1    KPJ15909.1    ODYU01012927    SOQ59469.1    PYGN01000603    PSN43506.1    RVE46607.1    GECZ01007935    JAS61834.1    NWSH01001989    PCG69504.1    GECU01029729    JAS77977.1    NWSH01004603    PCG64857.1    KPI98096.1    GEDC01018946    GEDC01008979    JAS18352.1    JAS28319.1    KQ971361    EFA05308.1    GGMR01003880    MBY16499.1    GEBQ01011235    JAT28742.1    LBMM01004254    KMQ92658.1    CVRI01000006    CRK88225.1    GBRD01012475    GBRD01012473    JAG53349.1    KQ434864    KZC08967.1    GEZM01088644    JAV58046.1    GBHO01038000    JAG05604.1    ODYU01010862    SOQ56231.1    LJIG01000707    KRT86233.1    GGMS01001703    MBY70906.1    GDHC01010234    JAQ08395.1    GBBI01002626    JAC16086.1    GBGD01001034    JAC87855.1    KQ461155    KPJ08368.1    GDQN01010353    JAT80701.1    GGFK01004578    MBW37899.1    GGFL01004110    MBW68288.1    GGFL01004789    MBW68967.1    GGFJ01003792    MBW52933.1    GGFL01004111    MBW68289.1    GGFJ01003793    MBW52934.1    GGFL01004788    MBW68966.1    OWR50761.1    ABLF02035671    GFXV01003482    MBW15287.1    CH477573    EAT38831.1    GGFM01002176    MBW22927.1    GGFM01002194    MBW22945.1    KB632410    ERL95208.1    GFDL01006801    JAV28244.1    GFDL01006875    JAV28170.1    DS231872    EDS41404.1    GL450313    EFN81185.1    GFDL01006731    JAV28314.1    GFDL01006678    JAV28367.1    AXCN02001200    KK107151    QOIP01000003    EZA57287.1    RLU24717.1    NWSH01005286    PCG64319.1    GDHF01018012    GDHF01013873    GDHF01003982    JAI34302.1    JAI38441.1    JAI48332.1    KK854400    PTY15462.1    GFDF01009514    JAV04570.1    AXCM01000458    GEZM01088643    GEZM01088642    JAV58047.1    AAAB01008898    EAL40562.4    GFDF01009508    JAV04576.1    GL888331    EGI62615.1    KQ981029    KYN10190.1    ADTU01003883    KQ976701    KYM77299.1    KQ983114    KYQ47337.1    GL437108    EFN71118.1    KQ977220    KYN04851.1    KQ981768    KYN35936.1    RSAL01000011    RVE53552.1    KQ414596    KOC69980.1    JXUM01102960    KQ564767    KXJ71770.1    GGMR01006492    MBY19111.1    ATLV01026865    ATLV01026866    KE525420    KFB53427.1    GL766050    EFZ15659.1    KQ459249    KPJ02439.1    BABH01009475    BABH01009476    BABH01009477    KQ436008    KOX67603.1    AGBW02014503    OWR41557.1    NEVH01021203    PNF19928.1    KPJ15906.1    GFXV01001690    MBW13495.1    GDHF01032155    GDHF01019937    GDHF01013697    GDHF01000723    JAI20159.1    JAI32377.1    JAI38617.1    JAI51591.1    KZ149899    PZC78617.1    KZ288292    PBC29176.1    KQ971354    EFA05964.2    GAKP01009377    JAC49575.1    KPI98098.1   

Proteomes

UP000053240    UP000053268    UP000283053    UP000007151    UP000245037    UP000218220    + More
UP000007266    UP000036403    UP000183832    UP000076502    UP000192223    UP000007819    UP000008820    UP000030742    UP000002320    UP000008237    UP000075886    UP000053097    UP000279307    UP000075880    UP000075883    UP000075903    UP000076407    UP000007062    UP000007755    UP000078492    UP000005205    UP000078540    UP000075809    UP000000311    UP000078542    UP000078541    UP000053825    UP000069940    UP000249989    UP000030765    UP000075884    UP000005204    UP000053105    UP000075881    UP000235965    UP000075900    UP000075885    UP000075920    UP000005203    UP000242457   

PRIDE

H9JAJ5   

Pfam

PF07690   MFS_1        + More
PF01401   Peptidase_M2
PF07701   HNOBA
PF00211   Guanylate_cyc
PF07700   HNOB

Interpro

IPR011701   MFS        + More
IPR020846   MFS_dom       
IPR036259   MFS_trans_sf       
IPR018297   A/G_cyclase_CS       
IPR038158   H-NOX_domain_sf       
IPR024096   NO_sig/Golgi_transp_ligand-bd       
IPR011645   HNOB_dom_associated       
IPR029787   Nucleotide_cyclase       
IPR001548   Peptidase_M2       
IPR001054   A/G_cyclase       
IPR011644   Heme_NO-bd       

SUPFAM

SSF103473   SSF103473        + More
SSF55073   SSF55073       
SSF111126   SSF111126       

Gene 3D

3.30.70.1230     3.90.1520.10    

CDD

cd06174  MFS
cd06461  M2_ACE

ProteinModelPortal

A0A194RE89   A0A194PXP8   A0A3S2PBF1   A0A212FAJ8   A0A212FAK5   A0A194REM1   + More
A0A2H1X2C4   A0A2P8YGX5   A0A3S2LH66   A0A1B6GHB7   A0A2A4JD86   A0A1B6HTG8   A0A2A4IY18   A0A194PXM6   A0A1B6CY04   D2A535   A0A2S2NH85   A0A1B6LYH9   A0A0J7KQN9   A0A1J1HPT6   A0A0K8SJM1   A0A154PAY0   A0A1W4WW74   A0A1Y1KF48   A0A0A9WCX6   A0A2H1WT49   A0A0T6BFY6   A0A2S2PZG0   A0A146LMI6   A0A023F3V3   A0A069DVE7   A0A194QS69   A0A1E1W1C8   A0A2M4AAV7   A0A2M4CTY3   A0A2M4CUE7   A0A2M4BIX1   A0A2M4CSN5   A0A2M4BIV5   A0A2M4CUE3   A0A212FAL1   J9KB87   A0A2H8TM94   Q16W79   A0A2M3Z330   A0A2M3Z363   U4URR0   A0A1Q3FL61   A0A1Q3FKN7   B0WAI1   E2BSZ7   A0A1Q3FLC7   A0A1Q3FLB8   A0A182QCE8   A0A026WMI6   A0A2A4IXD4   A0A182J2E5   A0A0K8VHS8   A0A2R7W706   A0A1L8DE03   A0A182MSS2   A0A182VHT3   A0A2C9H8S5   A0A1Y1KH29   Q5TSW5   A0A1L8DDP9   F4WT02   A0A151ITA2   A0A158NYI1   A0A195AZB4   A0A151WHP4   E2A659   A0A195CVZ7   A0A195F6C4   A0A3S2LGU6   A0A0L7RGJ1   A0A182H1C2   A0A2S2NPL3   A0A084WT83   A0A182N9U1   E9IUT7   A0A194QAI0   H9JAJ5   A0A0M8ZQJ4   A0A212EJ99   A0A182K2U1   A0A2J7PUC7   A0A194RIY8   A0A2H8THB2   A0A182RDY9   A0A182PQS5   A0A182W3L5   A0A0K8WKB4   A0A2W1BZD6   A0A088ANF5   A0A2A3EDD3   D6WRR1   A0A034W601   A0A194PYJ5  

KEGG

101745323    K20840 MFS transporter, PCFT/HCP family, solute carrier family 46, member 3 | (RefSeq) proton-couple

GO

GO:0055085   GO:0016021   GO:0008237   GO:0020037   GO:0000166   GO:0035556   GO:0004180   GO:0046872   GO:0004383   GO:0008241  

PANTHER

PTHR10514  

Length:

120

Number of predicted TMHs:

3

Exp number of AAs in TMHs:

58.28437

Exp number, first 60 AAs:

28.88617

Total prob of N-in:

0.24382

POSSIBLE N-term signal

sequence

outside

1  -  14

TMhelix

15  -  32

inside

33  -  44

TMhelix

45  -  67

outside

68  -  79

TMhelix

80  -  102

inside

103  -  120

 

 

Pi

18.678086

Theta

17.905852

Tajima's D

0.031176

CLR

0.882594

CSRT

0.384780760961952

Interpretation

Uncertain