Gene

KWMTBOMO13384

Pre Gene Modal

BGIBMGA010933

Annotation

PREDICTED:_proton-coupled_folate_transporter-like_[Papilio_machaon]

Location

Bomo_Chr22(+):15877699-15885878      View in EpiBrowser

Full name

Angiotensin-converting enzyme      

Location in the cell

PlasmaMembrane   Reliability : 4.845

CDS

ATGTCAAGTGAAAATACAAAGGAAGAAATCAACGAACAAGTACCAATTAATGAAAAAGATAATGTGAACAATAAAGACGAATTCGAGAATCGGAGTTTCTTTGATAAACTGTGCGAAATCAAATCTAACATAACAGTGGAGCCAATTTTCGCGGGATTAATTATACCTTCGACTTTGGCCAGATTGGCGATACAAAATTTGAATTTAGACAAAGCATGCCGCGTCAAATCACAGTTCGGAGACGTTGTCTGCGACGCACTGATCGAACGGAAAGGCAATTACACAACTCAAGAAGCCGAGATCCAGCAAATAATTTCACATATTGAATCATGGAGGACTATTATACAGACCGCCATACCCACACTTCTGGTTATCTTCATGGGAGCTTGGAGCGACAGGACGGGCAACAGAAAAATTTGCATACTCCTCCCAATCTTCGGTGAATTTATGGTCTGCGTGAGCAATGTATTGAGCACTTACTTCTTTTATGAGATTCCAGTCGAAACCACAATGTTCCTAGAAGCGATATTCCCAGCCATCACCGGAGGTTGGGTTTTAGTATACTTAGGAGTATTCAGCTACATAAGTGATATTACAGATGAGAAATCGAGGACGTTTCGAGTGGGCTTAGTGAATCTATGCTTGACGGCCGGAATTCCTATTGGTACAGCTCTTAGTGGAATTTTATTGAAATACTGGGGCTATTATGGCATTTTCTTGTCATCCGGCTCATTGTATTTCGCTACGTTTTTATACGGCTATTTCTATTTAGAAAGTAACACGAAGCCTAATGCTGGAAGCGATGAGGAGCCTAAACCGGTATCTTGTTTTGATCTAGTATCGCTAGTGAAAGAAACTGTTTCTGTCGCTTTCAAGAAACGTCAAGGGAATTTTAGATCAAAAATAATACTGACTTTGTTAGTAGTCGCCATAATATATGGACCCGATCATGGTGAAAGAATAATTACGTATCTATATTTGAGATACAAATTAAAATGGGATGCAGTTAAATACAGTTTATATTCAACCTACAGTATCATTACACATTCTTTCGGGGCACTTATCTCCATCAGTATCTTCAGCAAGCGTTGGGGATTCCACGATTCAGTGCTATGTCTCATCTCGATCCTAAGCAAATTAGCTGGCAGTATTAGCATGATATTCGTCCAAACCGACTTCCAAATGTACACGATTCCAATTGTGGAGATCTTGAATGCAACCACGTATACTTCACTGAGATCGTTAGCTTCAAAACTTATTCCTAGCGAAGAGATGGGTAAAATGAACTCTTTGTTCAGTCTGGTGGAGACATTGGCAGCTCTGGTTTTCGACCCCACATATTCGACGATATACGCGCGTACTGTATCAGTATTCACTGGAGCCGTGTACCTTTATAGCTCCCTCATGAGTATTCCAGCTATAGCCATTTTACTATGGATCTTCATAAAACATAGGCTGGAATTACGAAATCCCGAGAAAGAAATTGAGCTGAATAATAGTTCCTAA

Protein

MSSENTKEEINEQVPINEKDNVNNKDEFENRSFFDKLCEIKSNITVEPIFAGLIIPSTLARLAIQNLNLDKACRVKSQFGDVVCDALIERKGNYTTQEAEIQQIISHIESWRTIIQTAIPTLLVIFMGAWSDRTGNRKICILLPIFGEFMVCVSNVLSTYFFYEIPVETTMFLEAIFPAITGGWVLVYLGVFSYISDITDEKSRTFRVGLVNLCLTAGIPIGTALSGILLKYWGYYGIFLSSGSLYFATFLYGYFYLESNTKPNAGSDEEPKPVSCFDLVSLVKETVSVAFKKRQGNFRSKIILTLLVVAIIYGPDHGERIITYLYLRYKLKWDAVKYSLYSTYSIITHSFGALISISIFSKRWGFHDSVLCLISILSKLAGSISMIFVQTDFQMYTIPIVEILNATTYTSLRSLASKLIPSEEMGKMNSLFSLVETLAALVFDPTYSTIYARTVSVFTGAVYLYSSLMSIPAIAILLWIFIKHRLELRNPEKEIELNNSS

Cofactor

Zn(2+)

Similarity

Belongs to the peptidase M2 family.
Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.

Uniprot

A0A2H1WJM3   A0A194Q3W9   A0A212EU39   A0A3S2PEP4   A0A0L7KST7   A0A194REL6   + More
A0A212EU49   A0A194RDI4   A0A194PXN1   H9JN31   A0A2A4IW55   A0A2H1V1J8   A0A194RE89   A0A194PXP8   A0A212FAL1   A0A3S2PBF1   A0A212FAJ8   A0A194RDJ0   A0A212FAK5   A0A194REM1   A0A2A4IY18   A0A1Q3FLB8   A0A1Q3FLC7   Q16W79   B0WAI1   A0A2C9H8S5   Q5TSW5   A0A182QCE8   A0A182VHT3   A0A182J2E5   A0A182MSS2   A0A2M4BIX1   A0A2M4BIV5   A0A2M4CUE3   A0A1B6CY04   A0A2M3Z330   A0A2M4CUE7   A0A2M4CSN5   A0A069DVE7   A0A2M3Z363   A0A2M4CTY3   A0A0L7L4E3   A0A2W1BZD6   A0A1J1HPT6   A0A2M4AAV7   A0A1B6LYH9   A0A067RJA9   A0A023F3V3   A0A194PXM6   A0A194QAI0   A0A146LMI6   W8C3P0   A0A1I8M3Q0   A0A3S2LGU6   B3NUZ2   H9JAJ5   B4PW63   A0A1I8PUY1   Q9VY22   Q6NPA2   J9KB87   B4R4V6   A0A1Y1KH29   A0A1B6HTG8   A0A2H1W938   A0A1W4WW74   B3N1F7   A0A1W4VHL4   A0A154PAY0   B4M2P7   A0A0L0C7Q4   A0A034W601   B4GY42   A0A3B0K378   Q29H91   B4L4F7   A0A026WMI6   B4JJN3   A0A0K8WKB4   A0A2H8TM94   B4NPQ3   A0A182N9U1   A0A0L7LL21   A0A0M4FAI8   A0A0A1XR69   A0A182PQS5   A0A0L7RGJ1   A0A182RDY9   A0A0M8ZQJ4   D2A535   A0A182W3L5   A0A3S2LLF7   E2BSZ7   A0A084WT83   A0A2A3EDD3   E2A659   U4URR0   A0A088ANF5   A0A194PYJ5  

EC Number

3.4.-.-

Pubmed

26354079    22118469    26227816    19121390    17510324    12364791    + More
14747013    17210077    26334808    28756777    24845553    25474469    26823975    24495485    25315136    17994087    17550304    10731132    12537568    12537572    12537573    12537574    16110336    17569856    17569867    26109357    26109356    28004739    26108605    25348373    15632085    24508170    30249741    25830018    18362917    19820115    20798317    24438588    23537049   

EMBL

ODYU01009084    SOQ53249.1    KQ459586    KPI98100.1    AGBW02012463    OWR45015.1    + More
RSAL01000068    RVE49267.1    JTDY01006280    KOB66145.1    KQ460323    KPJ15904.1    OWR45016.1    KPJ15903.1    KPI98101.1    BABH01030471    NWSH01006054    PCG63706.1    ODYU01000073    SOQ34212.1    KPJ15907.1    KPI98097.1    AGBW02009461    OWR50761.1    RSAL01000124    RVE46608.1    OWR50762.1    KPJ15908.1    OWR50760.1    KPJ15909.1    NWSH01004603    PCG64857.1    GFDL01006678    JAV28367.1    GFDL01006731    JAV28314.1    CH477573    EAT38831.1    DS231872    EDS41404.1    AAAB01008898    EAL40562.4    AXCN02001200    AXCM01000458    GGFJ01003792    MBW52933.1    GGFJ01003793    MBW52934.1    GGFL01004788    MBW68966.1    GEDC01018946    GEDC01008979    JAS18352.1    JAS28319.1    GGFM01002176    MBW22927.1    GGFL01004789    MBW68967.1    GGFL01004111    MBW68289.1    GBGD01001034    JAC87855.1    GGFM01002194    MBW22945.1    GGFL01004110    MBW68288.1    JTDY01002998    KOB70347.1    KZ149899    PZC78617.1    CVRI01000006    CRK88225.1    GGFK01004578    MBW37899.1    GEBQ01011235    JAT28742.1    KK852651    KDR19441.1    GBBI01002626    JAC16086.1    KPI98096.1    KQ459249    KPJ02439.1    GDHC01010234    JAQ08395.1    GAMC01005989    JAC00567.1    RSAL01000011    RVE53552.1    CH954180    EDV47090.1    BABH01009475    BABH01009476    BABH01009477    CM000162    EDX01694.1    KRK06299.1    AE014298    BT133123    AAF48383.1    AEY64291.1    BT011024    AAR30184.1    ABLF02035671    CM000366    EDX17913.1    GEZM01088643    GEZM01088642    JAV58047.1    GECU01029729    JAS77977.1    ODYU01007104    SOQ49580.1    CH902654    EDV33596.1    KQ434864    KZC08967.1    CH940651    EDW65951.1    JRES01000902    KNC27439.1    GAKP01009377    JAC49575.1    CH479196    EDW27669.1    OUUW01000015    SPP88717.1    CH379064    EAL31867.2    CH933810    EDW07435.1    KK107151    QOIP01000003    EZA57287.1    RLU24717.1    CH916370    EDV99785.1    GDHF01032155    GDHF01019937    GDHF01013697    GDHF01000723    JAI20159.1    JAI32377.1    JAI38617.1    JAI51591.1    GFXV01003482    MBW15287.1    CH964291    EDW86493.1    JTDY01000713    KOB76125.1    CP012528    ALC49420.1    GBXI01016992    GBXI01013508    GBXI01006853    GBXI01003332    GBXI01000927    JAC97299.1    JAD00784.1    JAD07439.1    JAD10960.1    JAD13365.1    KQ414596    KOC69980.1    KQ436008    KOX67603.1    KQ971361    EFA05308.1    RVE49265.1    GL450313    EFN81185.1    ATLV01026865    ATLV01026866    KE525420    KFB53427.1    KZ288292    PBC29176.1    GL437108    EFN71118.1    KB632410    ERL95208.1    KPI98098.1   

Proteomes

UP000053268    UP000007151    UP000283053    UP000037510    UP000053240    UP000005204    + More
UP000218220    UP000008820    UP000002320    UP000076407    UP000007062    UP000075886    UP000075903    UP000075880    UP000075883    UP000183832    UP000027135    UP000095301    UP000008711    UP000002282    UP000095300    UP000000803    UP000007819    UP000000304    UP000192223    UP000007801    UP000192221    UP000076502    UP000008792    UP000037069    UP000008744    UP000268350    UP000001819    UP000009192    UP000053097    UP000279307    UP000001070    UP000007798    UP000075884    UP000092553    UP000075885    UP000053825    UP000075900    UP000053105    UP000007266    UP000075920    UP000008237    UP000030765    UP000242457    UP000000311    UP000030742    UP000005203   

PRIDE

H9JN31    H9JAJ5    Q9VY22    Q6NPA2   

Pfam

PF07690   MFS_1        + More
PF01401   Peptidase_M2
PF07701   HNOBA
PF00211   Guanylate_cyc
PF07700   HNOB

Interpro

IPR036259   MFS_trans_sf        + More
IPR011701   MFS       
IPR020846   MFS_dom       
IPR001548   Peptidase_M2       
IPR018297   A/G_cyclase_CS       
IPR038158   H-NOX_domain_sf       
IPR024096   NO_sig/Golgi_transp_ligand-bd       
IPR011645   HNOB_dom_associated       
IPR029787   Nucleotide_cyclase       
IPR001054   A/G_cyclase       
IPR011644   Heme_NO-bd       

SUPFAM

SSF103473   SSF103473        + More
SSF55073   SSF55073       
SSF111126   SSF111126       

Gene 3D

3.30.70.1230     3.90.1520.10    

CDD

cd06174  MFS
cd06461  M2_ACE

ProteinModelPortal

A0A2H1WJM3   A0A194Q3W9   A0A212EU39   A0A3S2PEP4   A0A0L7KST7   A0A194REL6   + More
A0A212EU49   A0A194RDI4   A0A194PXN1   H9JN31   A0A2A4IW55   A0A2H1V1J8   A0A194RE89   A0A194PXP8   A0A212FAL1   A0A3S2PBF1   A0A212FAJ8   A0A194RDJ0   A0A212FAK5   A0A194REM1   A0A2A4IY18   A0A1Q3FLB8   A0A1Q3FLC7   Q16W79   B0WAI1   A0A2C9H8S5   Q5TSW5   A0A182QCE8   A0A182VHT3   A0A182J2E5   A0A182MSS2   A0A2M4BIX1   A0A2M4BIV5   A0A2M4CUE3   A0A1B6CY04   A0A2M3Z330   A0A2M4CUE7   A0A2M4CSN5   A0A069DVE7   A0A2M3Z363   A0A2M4CTY3   A0A0L7L4E3   A0A2W1BZD6   A0A1J1HPT6   A0A2M4AAV7   A0A1B6LYH9   A0A067RJA9   A0A023F3V3   A0A194PXM6   A0A194QAI0   A0A146LMI6   W8C3P0   A0A1I8M3Q0   A0A3S2LGU6   B3NUZ2   H9JAJ5   B4PW63   A0A1I8PUY1   Q9VY22   Q6NPA2   J9KB87   B4R4V6   A0A1Y1KH29   A0A1B6HTG8   A0A2H1W938   A0A1W4WW74   B3N1F7   A0A1W4VHL4   A0A154PAY0   B4M2P7   A0A0L0C7Q4   A0A034W601   B4GY42   A0A3B0K378   Q29H91   B4L4F7   A0A026WMI6   B4JJN3   A0A0K8WKB4   A0A2H8TM94   B4NPQ3   A0A182N9U1   A0A0L7LL21   A0A0M4FAI8   A0A0A1XR69   A0A182PQS5   A0A0L7RGJ1   A0A182RDY9   A0A0M8ZQJ4   D2A535   A0A182W3L5   A0A3S2LLF7   E2BSZ7   A0A084WT83   A0A2A3EDD3   E2A659   U4URR0   A0A088ANF5   A0A194PYJ5  

KEGG

101745861    K20840 MFS transporter, PCFT/HCP family, solute carrier family 46, member 3 | (RefSeq) proton-couple

GO

GO:0016021   GO:0055085   GO:0004180   GO:0008237   GO:0008241   GO:0046872   GO:0020037   GO:0000166   GO:0035556   GO:0004383   GO:0008270   GO:0007018   GO:0008017   GO:0005525   GO:0031386   GO:0048869   GO:0003676   GO:0016491   GO:0015930  

PANTHER

PTHR10514  

Length:

501

Number of predicted TMHs:

7

Exp number of AAs in TMHs:

197.3041

Exp number, first 60 AAs:

3.06685

Total prob of N-in:

0.59743

inside

1  -  140

TMhelix

141  -  163

outside

164  -  172

TMhelix

173  -  195

inside

196  -  207

TMhelix

208  -  230

outside

231  -  234

TMhelix

235  -  257

inside

258  -  337

TMhelix

338  -  360

outside

361  -  369

TMhelix

370  -  389

inside

390  -  459

TMhelix

460  -  482

outside

483  -  501

 

 

Pi

25.328805

Theta

22.586443

Tajima's D

0.26906

CLR

0.62315

CSRT

0.450327483625819

Interpretation

Uncertain