Gene

KWMTBOMO13380

Annotation

reverse_transcriptase_[Lasius_niger]

Location

Bomo_Chr22(-):15805757-15808668      View in EpiBrowser

Full name

Probable RNA-directed DNA polymerase from transposon X-element       + More
RNA-directed DNA polymerase from mobile element jockey      
Probable RNA-directed DNA polymerase from transposon BS      

Alternative Name

Reverse transcriptase

Location in the cell

Nuclear   Reliability : 2.531

CDS

ATGTTCTCGTTGCGCATCGCTACCTGGAATATCAATGGATTGGCGCCAAATAAACAGGAGCTAGAAATTTTGCTCAAGCTTAATAAAATAGACATTGCGCTAATATCAGAAACTCATCTTAATGACAATAGAACAATTTTGATAGATAACTATAGTGTATATAACACAAATCATCCTAATGGAACTTCACATGGAGGAACCGCCGTTCTTATTAAAAATAACATAAGGCATAATGTACACAGTGCTTTTCGAGAGGAATGGCTTCAAGCTACTACTATAACTATAAACGAAAAGTTTGGGCCTATTAACATCAGTGCTATCTACTGTCCACCAAAACACAATCCTAAGCAAGATATGTTTAATAAATTCTTCAACACTTTGGGCAATAAATTTATAAGCGGAGGTGATTGGAACTGCAAGAATACATTCTGGGGATCACTGTTGACAACTACTAAGGGACGTGAACTGAAAAAAAGTGCTGATGATTGCAAGCTAACAATCCTTGGAACAGGTGAACCTACCTACTGGCCAACAGATACAAATAGACTTCCAGATCTGGTGGACTTTTTTATAATAAAGGGTCTTTCATATGTATATTTTGAAGTTGAGTCATCACTTGATTCTGTGTCGGATCACACTCCTGTCATAGCAACATTTAGCATCTCACCTATACAAAAAGAACAAAAAGAAGTACTATATAATTATAAAACAGACTGGAACTCATTCAGCGATTATCTAGAGGAAGAAATTAAACTTAGTGTTAAACTTAAAACAGAAGAAGATATAGATGAGGCAACATTTTATATCACAAACCTCATTCAAGTGGCTGCGTGGCATTCCACTCCAAAATTAAGCGATCATACTGTTAGTAATAATATACCTATGGAAATACGCCACAAACTTCAAGTAAAGAGAAAGCTAAGAAGGCAACTCCACATGACAAGATCCGATATAGACAGAAAAGAATTTAATAAAATCTCAAGAGAACTAAAAGAACTAATCAATGAATCTGTCAACTCAGCATTTCATCATAAAATATCAGGGCTCTCAGCATACAAGAAGGACAATTATTCTTTATGGAAAATCACCAAAAACTTCAAAAAACCTAAAAGCCATATTCCACCAATGAGGAAATCGCCAACCGACCCTTGGGCCAAGAGTACAACTGAAAAAGCTGAGCTATTTGCAAATTACTTGTATGAAATATTTACCCCTAACCTATCACCAATGGAGGACTATGAAAAAGAAGTTGATGTCATGATTAATAGTGACCAGCAGCTATCCCTGCCACTCAAATCCGTCACCCCCAGGGAACTTACGCAATGTATACAGTCTCTTAAAAATAAAAAAGCTCCTGGTTTTGATTTAATAACTGGTGAGGTACTTAAAAAATTGCCCAAAAAAGTAATAATATTTTTAACAATGTTATTCAATGCTATCCTCAGAGTACATTATTACCCAAAACTCTGGCAAATAGCACAAGTCTGCATGGTTATAAAGCCTGGAAAACCAGCGTCAGATCCAAGTTCATATAGGCCCATAAGTCTTCTACCTGTGTTGTCTAAGGTATTTGAAACGGTATTTCTAAAAAGACTGAAGCCGCTTCTTGACCAGGAAAAGATTATACCGGATCATCAGTTTGGATTTCGGGCGAAGCATTCTACTGTCGAACAAGTACACAGAGTAGTTCATAAAATTCGACAATCCTTAGAAAAGAAGGAATACTGTTCTGCGGCATTTATTGACATCAAGCAAGCTTTCGATAAAGTCTGGCATAAGGGATTACTATATAAATTGAAAACCCTCCTACCGAATTCTTTTTTCATGCTCCTGAGATCCTACTTAAAACACAGAAAATTCCAAGTCAAATTTGGAGAGGACTGTTCGAAGCTGTATAATATTAACGCCTCCGTACCCCAGGGATCAGTGCTTGGTCCGGTCCTGTTTTCTATCTATACTGCAGACCTGCCTCAATCCCAAGATGTTGTAACTGCGACTTACGCTGACGATACAGCTTGTCTGGCAAGTGACATAGATCCACATAATGCATCATTACAACTACAAGTACAGCTTGACAAAGTGGATGCTTGGCTGCAGAGATGGCGATTAAAACCTAGTGTAACTAAGTCAACGCAGGTAACATTCACCCTTCGGAAAGGTGTCTGTGACCCTGTTTACATGGAAGGTAAAGCTTTACCAAATGCCGACTCTGTGAAATACTTGGGATTACACCTCGACAGAAGATTAACCTGGGCGAACCATATAAAAGCAAAAAAACGAGAAGCGAACTTGCAATTTCTCTCTTTGAATTGGTTACTGGGACGCCGGTCTCCACTGTCACTAAGTAACAAACTCCTGGTCTACAAAGCGATTATAAAACCTGTCTGGACTTATGGAATAGAACTGTGGGGTTCCGCTAGCAACTCGAATATCGAGATCTTACAGAGATTCCAGAACATTGCTCTTAGAACTATCTCAAACGCGCATTGGTTTGTAAGAAATAGTGAGATTCACGAATACTTAGAAATGCCGACTGTTCGAGAGGAAGTCAACAAGAACAGCAAGAGATATAAGGAAAGACTAAATGAGCACTCAAATGAATTGGCAAGGTGCCTGCTAGACACAACTGGAGATGTGAAACGTTTAAAAAGATGGCAAATTTTAGACTTAGACCAAAGATACTAA

Protein

MFSLRIATWNINGLAPNKQELEILLKLNKIDIALISETHLNDNRTILIDNYSVYNTNHPNGTSHGGTAVLIKNNIRHNVHSAFREEWLQATTITINEKFGPINISAIYCPPKHNPKQDMFNKFFNTLGNKFISGGDWNCKNTFWGSLLTTTKGRELKKSADDCKLTILGTGEPTYWPTDTNRLPDLVDFFIIKGLSYVYFEVESSLDSVSDHTPVIATFSISPIQKEQKEVLYNYKTDWNSFSDYLEEEIKLSVKLKTEEDIDEATFYITNLIQVAAWHSTPKLSDHTVSNNIPMEIRHKLQVKRKLRRQLHMTRSDIDRKEFNKISRELKELINESVNSAFHHKISGLSAYKKDNYSLWKITKNFKKPKSHIPPMRKSPTDPWAKSTTEKAELFANYLYEIFTPNLSPMEDYEKEVDVMINSDQQLSLPLKSVTPRELTQCIQSLKNKKAPGFDLITGEVLKKLPKKVIIFLTMLFNAILRVHYYPKLWQIAQVCMVIKPGKPASDPSSYRPISLLPVLSKVFETVFLKRLKPLLDQEKIIPDHQFGFRAKHSTVEQVHRVVHKIRQSLEKKEYCSAAFIDIKQAFDKVWHKGLLYKLKTLLPNSFFMLLRSYLKHRKFQVKFGEDCSKLYNINASVPQGSVLGPVLFSIYTADLPQSQDVVTATYADDTACLASDIDPHNASLQLQVQLDKVDAWLQRWRLKPSVTKSTQVTFTLRKGVCDPVYMEGKALPNADSVKYLGLHLDRRLTWANHIKAKKREANLQFLSLNWLLGRRSPLSLSNKLLVYKAIIKPVWTYGIELWGSASNSNIEILQRFQNIALRTISNAHWFVRNSEIHEYLEMPTVREEVNKNSKRYKERLNEHSNELARCLLDTTGDVKRLKRWQILDLDQRY

Catalytic Activity

a 2'-deoxyribonucleoside 5'-triphosphate + DNA(n) = diphosphate + DNA(n+1)

Cofactor

Mg(2+)
Mn(2+)

Miscellaneous

At least 30 copies of X-element are present in the genome and some elements are polymorphic between different strains.
Prefers poly(rC) and poly(rA) as template and activated DNA is not effective.

Keywords

Nucleotidyltransferase   RNA-directed DNA polymerase   Transferase   Transposable element  

Feature

chain  Probable RNA-directed DNA polymerase from transposon X-element

Uniprot

A0A2A4K918   A0A2J7R4U3   A0A2A4IUM2   A0A2J7Q9Z1   A0A2J7PSM7   A0A2J7QES2   + More
A0A2J7R7D0   A0A2J7QB68   A0A2J7RQ52   A0A2J7R098   A0A2J7PMN4   A0A2J7PVX3   A0A2J7PDM0   A0A2J7RD70   A0A2J7Q0S7   J9LYS0   A0A1Y1KFR3   A0A0A9YU04   A0A1Y1LKN6   A0A0A9YJ00   A0A0J7MYU2   A0A224X6T4   A0A1B6EGD8   A0A142LX26   A0A224X6U5   A0A142LX53   A0A224XJI0   A0A2S2NPJ7   A0A2S2N814   A0A224XI99   A0A352X8G4   Q6R811   Q04135   A0A224X6R6   A0A2S2N6Q7   A0A142LX49   A0A224XHW8   A0A069DX78   A0A224X746   A0A2S2P6S3   Q961V7   A0A2S2NGV8   A0A2J7PVE7   A0A2H8TF37   X1WUG2   Q24335   A0A0M4EWX7   A0A2S2PJG2   A0A034VFD2   A0A224X6S1   A0A2S2NH02   A0A0V0G5B6   A0A0J7K7J8   A0A023F0I3   A0A2S2NPG3   A0A224X6W2   A0A224X724   A0A2H8TKI9   A0A2J7R8R8   A0A224XIB0   A0A2S2NKC3   A0A2S2P7B2   A0A2S2P698   A0A0J7K811   A0A2S2R9D4   A0A2S2P6C4   A0A2S2PHL7   A0A2S2QDN9   A0A0A9YSX4   A0A2S2P3X8   A0A146KRW8   A0A224X7Z3   X1XLN5   A0A2S2PUS3   A0A0J7NDW4   A0A2S2QEE0   J9M0H4   A0A224XK92   A0A0J7K3N0   A0A1L8DIZ6   A0A023F069   A0A1Y1MT28   A0A2S2PA10   Q9NBX4   A0A1B6C2V8   J9LMA3   J9KWJ0   P21328   J9KSK5   J9KLB1   Q95SX7   A0A2S2Q2R8   P21329   A0A146KV64   A0A224XIV5   A0A1Y1KFT3   A0A2S2N9P4  

EC Number

2.7.7.49

Pubmed

28004739    25401762    25527032    30148503    14745026    1705654    + More
26334808    2441397    25348373    25474469    26823975    11405632    2463954    3040362    1714378    7753626    12537569    1701254   

EMBL

NWSH01000032    PCG80496.1    NEVH01007402    PNF35856.1    NWSH01007753    PCG62823.1    + More
NEVH01016340    PNF25410.1    NEVH01021925    PNF19341.1    NEVH01015305    PNF27092.1    NEVH01006736    PNF36716.1    NEVH01016302    PNF25823.1    NEVH01001347    PNF42959.1    NEVH01008277    PNF34262.1    NEVH01023979    PNF17579.1    NEVH01020940    PNF20481.1    NEVH01026386    PNF14434.1    NEVH01005295    PNF38784.1    NEVH01019963    PNF22185.1    ABLF02041861    GEZM01084969    JAV60363.1    GBHO01021814    GBHO01010549    JAG21790.1    JAG33055.1    GEZM01053022    JAV74219.1    GBHO01010547    GBHO01010546    JAG33057.1    JAG33058.1    LBMM01013518    KMQ85605.1    GFTR01008261    JAW08165.1    GEDC01000337    JAS36961.1    KU543673    AMS38352.1    GFTR01008251    JAW08175.1    KU543687    AMS38379.1    GFTR01008257    JAW08169.1    GGMR01006491    MBY19110.1    GGMR01000676    MBY13295.1    GFTR01008256    JAW08170.1    DNOY01000259    HBE18313.1    AY508487    AAS13459.1    X17551    CAA35587.1    GFTR01008269    JAW08157.1    GGMR01000226    MBY12845.1    KU543685    AMS38375.1    GFTR01008254    JAW08172.1    GBGD01000389    JAC88500.1    GFTR01008151    JAW08275.1    GGMR01012443    MBY25062.1    AY047531    AAK77263.1    GGMR01003407    MBY16026.1    NEVH01020963    PNF20308.1    GFXV01000908    MBW12713.1    ABLF02016613    M17214    AAA28508.1    CP012527    ALC48130.1    GGMR01016905    MBY29524.1    GAKP01017773    JAC41179.1    GFTR01008271    JAW08155.1    GGMR01003864    MBY16483.1    GECL01003538    JAP02586.1    LBMM01012041    KMQ86458.1    GBBI01003747    JAC14965.1    GGMR01006408    MBY19027.1    GFTR01008260    JAW08166.1    GFTR01008169    JAW08257.1    GFXV01002840    MBW14645.1    NEVH01006721    PNF37225.1    GFTR01008246    JAW08180.1    GGMR01005022    MBY17641.1    GGMR01012676    MBY25295.1    GGMR01012305    MBY24924.1    LBMM01012078    KMQ86419.1    GGMS01017365    MBY86568.1    GGMR01012283    MBY24902.1    GGMR01016296    MBY28915.1    GGMS01006655    MBY75858.1    GBHO01008295    JAG35309.1    GGMR01011511    MBY24130.1    GDHC01020244    JAP98384.1    GFTR01007929    JAW08497.1    ABLF02017755    ABLF02044739    ABLF02063495    ABLF02065698    ABLF02066197    GGMR01020516    MBY33135.1    LBMM01006314    KMQ90710.1    GGMS01006359    MBY75562.1    ABLF02034460    GFTR01007997    JAW08429.1    LBMM01015125    KMQ84919.1    GFDF01007661    JAV06423.1    GBBI01003810    JAC14902.1    GEZM01021881    JAV88842.1    GGMR01013409    MBY26028.1    AF237761    AAF81411.1    GEDC01029594    JAS07704.1    ABLF02025048    ABLF02063033    ABLF02021819    ABLF02021820    ABLF02055326    M22874    M38643    ABLF02014118    ABLF02014121    ABLF02054790    ABLF02040174    ABLF02040183    ABLF02055266    AY060438    AAL25477.1    GGMS01002786    MBY71989.1    M38437    GDHC01018248    JAQ00381.1    GFTR01007904    JAW08522.1    GEZM01084970    JAV60359.1    GGMR01000857    MBY13476.1   

Proteomes

UP000218220    UP000235965    UP000007819    UP000036403    UP000092553   

PRIDE

Q04135    Q961V7    Q24335    Q9NBX4    P21328    Q95SX7    + More
P21329   

Pfam

PF00078   RVT_1        + More
PF14529   Exo_endo_phos_2
PF07530   PRE_C2HC
PF03372   Exo_endo_phos

Interpro

IPR036691   Endo/exonu/phosph_ase_sf        + More
IPR005135   Endo/exonuclease/phosphatase       
IPR000477   RT_dom       
IPR006579   Pre_C2HC_dom       

SUPFAM

SSF56219   SSF56219       

Gene 3D

3.60.10.10    

ProteinModelPortal

A0A2A4K918   A0A2J7R4U3   A0A2A4IUM2   A0A2J7Q9Z1   A0A2J7PSM7   A0A2J7QES2   + More
A0A2J7R7D0   A0A2J7QB68   A0A2J7RQ52   A0A2J7R098   A0A2J7PMN4   A0A2J7PVX3   A0A2J7PDM0   A0A2J7RD70   A0A2J7Q0S7   J9LYS0   A0A1Y1KFR3   A0A0A9YU04   A0A1Y1LKN6   A0A0A9YJ00   A0A0J7MYU2   A0A224X6T4   A0A1B6EGD8   A0A142LX26   A0A224X6U5   A0A142LX53   A0A224XJI0   A0A2S2NPJ7   A0A2S2N814   A0A224XI99   A0A352X8G4   Q6R811   Q04135   A0A224X6R6   A0A2S2N6Q7   A0A142LX49   A0A224XHW8   A0A069DX78   A0A224X746   A0A2S2P6S3   Q961V7   A0A2S2NGV8   A0A2J7PVE7   A0A2H8TF37   X1WUG2   Q24335   A0A0M4EWX7   A0A2S2PJG2   A0A034VFD2   A0A224X6S1   A0A2S2NH02   A0A0V0G5B6   A0A0J7K7J8   A0A023F0I3   A0A2S2NPG3   A0A224X6W2   A0A224X724   A0A2H8TKI9   A0A2J7R8R8   A0A224XIB0   A0A2S2NKC3   A0A2S2P7B2   A0A2S2P698   A0A0J7K811   A0A2S2R9D4   A0A2S2P6C4   A0A2S2PHL7   A0A2S2QDN9   A0A0A9YSX4   A0A2S2P3X8   A0A146KRW8   A0A224X7Z3   X1XLN5   A0A2S2PUS3   A0A0J7NDW4   A0A2S2QEE0   J9M0H4   A0A224XK92   A0A0J7K3N0   A0A1L8DIZ6   A0A023F069   A0A1Y1MT28   A0A2S2PA10   Q9NBX4   A0A1B6C2V8   J9LMA3   J9KWJ0   P21328   J9KSK5   J9KLB1   Q95SX7   A0A2S2Q2R8   P21329   A0A146KV64   A0A224XIV5   A0A1Y1KFT3   A0A2S2N9P4  

KEGG

NA   

GO

GO:0003964   GO:0006313  

Length:

894

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.11729

Exp number, first 60 AAs:

0

Total prob of N-in:

0.00122

outside

1  -  894

 

 

Pi

19.490342

Theta

25.407928

Tajima's D

-1.315929

CLR

22.900073

CSRT

0.0848457577121144

Interpretation

Uncertain