Gene

KWMTBOMO13353

Pre Gene Modal

BGIBMGA010920

Annotation

PREDICTED:_elongation_of_very_long_chain_fatty_acids_protein_7-like_[Bombyx_mori]

Location

Bomo_Chr22(+):14711155-14721142      View in EpiBrowser

Full name

Elongation of very long chain fatty acids protein      

Alternative Name

Very-long-chain 3-oxoacyl-CoA synthase

Location in the cell

PlasmaMembrane   Reliability : 4.658

CDS

ATGGCTCTGATATTGAAGAAATCATGGGAAGCATATCAATTACTGTTTGAAGAATTGCCTGATCCCCGGATGAAGAACCTACCATTGTTGGCGAAACCCTATGAAGTGATAACATTACTGACCCTCTACTTAATGTTTGTGTTAAAATGGGGACCGAAATGGATGGAAAAGAGGCCTCCGTTCAATATTGACAAAGTTCTGATTATTTATAACTTGTTACAAGTATTGGCCTGCTCTTATCTATTTGTCGCATCTGCCTACGTCTGGGGTTGGAAGTACAAATGGATATGCGAGCCAGTGGACTTCTCTTACAATGATGATGCAATTTTTGTAACAAGATTGACTTATTTGTATTTTATTCTCAAATTACTAGATCTAATGGATACCGTGTTCTTCGTTCTGAGGAAGAAATTCAATCAAGTATCTTTCCTTCACCTGTATCATCATACAGGAATGGTGCTTCTCGTTTGGGGAGCTAATACCTATATTCCTGGTGGTCACGGTACGTTTATTGGGGTAATAAATTCCTTCGTCCATAGTGTCATGTATTTCTATTATTTCCTGACAGTGGTCAATCCGAGTTATAAGCAATCAATTTGGTGGAAAAAGCATATTACGCAACTTCAAATCCTTCAATTCTTTTGGTGTGTTGTTCATATGGGCATCATTGTGTTTAAGCCAGACTGCGAATATCCGAGATGGACCAGTGCAGTTTTTCTACCTCAAGACTTGTTCATGCTAGTTCTCTTTGTAGACTTCTATATCAAAACGTACATTAAGAAACCAAAAGCTAAACTTGAAGATCAAAACGACTCGAACGGTAAATATGTTGCAAATGGTAGCACCATAGCTGAGACGGCAATTGATAGCAACAGTATAGAAGATAGTAAAAAGGTTCTAATCAATAATGAAAATAGCATTAGTTATACCTTAGAAGATAAATGTGAATTTGAACAATTGAGCAATGCTATTTTGAAAGTAAGAAAATTAGGTGCGCTGAACAAACCTAACAATGATAAAAAAATGAAGGAGGATAAGTTTAAAAATGGGAATCACAAATAA

Protein

MALILKKSWEAYQLLFEELPDPRMKNLPLLAKPYEVITLLTLYLMFVLKWGPKWMEKRPPFNIDKVLIIYNLLQVLACSYLFVASAYVWGWKYKWICEPVDFSYNDDAIFVTRLTYLYFILKLLDLMDTVFFVLRKKFNQVSFLHLYHHTGMVLLVWGANTYIPGGHGTFIGVINSFVHSVMYFYYFLTVVNPSYKQSIWWKKHITQLQILQFFWCVVHMGIIVFKPDCEYPRWTSAVFLPQDLFMLVLFVDFYIKTYIKKPKAKLEDQNDSNGKYVANGSTIAETAIDSNSIEDSKKVLINNENSISYTLEDKCEFEQLSNAILKVRKLGALNKPNNDKKMKEDKFKNGNHK

Catalytic Activity

a very-long-chain acyl-CoA + H(+) + malonyl-CoA = a very-long-chain 3-oxoacyl-CoA + CO2 + CoA

Similarity

Belongs to the ELO family.

Uniprot

A0A2A4IXM8   A0A2H1X404   A0A3S2LZE4   A0A194REI7   A0A194PXS6   A0A212EGR1   + More
A0A1W4X4I0   A0A1S4FIU2   Q16ZG9   A0A182QU28   A0A182FG76   A0A182JTP0   A0A182NKP9   W5J681   A0A182KQS6   A0A182I2U4   A0A182P229   A0A182XLN3   A0A182UI04   A0A182UUZ5   Q5TWT4   A0A182GM29   A0A084VQU4   A0A1Q3FPY2   A0A182LV12   A0A1B0D2D9   A0A1B0CDB2   A0A0C9QVK2   A0A1W4WV14   A0A1J1HH34   B0W3U8   A0A182G240   A0A182RTX0   A0A182WJN4   A0A1S3D6M0   K7J7X7   A0A182YMP4   A0A1B6CQ89   D6X2U6   A0A182F0V7   A0A088ARV5   A0A0L7RDM4   A0A182M983   A0A182NB63   A0A182QAU9   A0A182PW57   A0A182VTN0   A0A182IB52   A0A182VEV3   A0A182TLQ9   A0A182LJX9   Q7PPN4   A0A182X629   A0A1Y1KWU6   A0A182K6I1   A0A3L8DHL5   A0A182Y8I0   W5J4Z1   A0A084VMS9   A0A088ARL4   A0A182T880   Q17HH4   A0A0A1XAY8   A0A023EP01   A0A1B6EHW1   Q16EQ4   A0A182ISK0   A0A2A3EJY7   A0A1Q3G529   A0A067R7E0   A0A182RA82   A0A1B6K697   A0A1B6G5V2   A0A1B6L6Z1   A0A1B0CDB4   A0A0L7RD74   A0A2J7QVQ5   A0A154PA26   A0A336LRW1   A0A1S3D216   A0A2J7QVP9   W8BNS1   A0A146LSJ0   A0A026VZ79   R4G7V2   A0A182Q8T4   A0A034W2T7   T1IE92   A0A0A9XVZ3   A0A1B0D2E0   A0A2H1X230   A0A0K8VS01   I4DN09   A0A2A4K8W8   A0A212FJ78   A0A0K8W144   Q17Q14   A0A182H129  

EC Number

2.3.1.199

Pubmed

26354079    22118469    17510324    20920257    23761445    20966253    + More
12364791    14747013    17210077    26483478    24438588    20075255    25244985    18362917    19820115    28004739    30249741    25830018    24945155    24845553    24495485    26823975    24508170    25348373    25401762    22651552   

EMBL

NWSH01005499    PCG64158.1    ODYU01012850    SOQ59354.1    RSAL01000100    RVE47558.1    + More
KQ460323    KPJ15879.1    KQ459586    KPI98127.1    AGBW02015045    OWR40662.1    CH477491    EAT40021.1    AXCN02000544    ADMH02002078    ETN59501.1    APCN01000180    AAAB01008807    EAL41836.3    JXUM01073484    KQ562778    KXJ75141.1    ATLV01015326    KE525006    KFB40338.1    GFDL01005509    JAV29536.1    AXCM01004785    AJVK01022764    AJWK01007640    GBYB01004697    JAG74464.1    CVRI01000002    CRK86866.1    DS231833    EDS32245.1    JXUM01039162    KQ561193    KXJ79407.1    GEDC01021621    JAS15677.1    KQ971372    EFA10642.1    KQ414614    KOC68919.1    AXCM01003970    AXCN02000640    APCN01000639    AAAB01008944    EAA10106.4    GEZM01077270    GEZM01077269    GEZM01077268    GEZM01077267    JAV63347.1    QOIP01000008    RLU19338.1    ADMH02002132    ETN58473.1    ATLV01014624    KE524975    KFB39273.1    CH477248    EAT46133.1    GBXI01006392    JAD07900.1    JXUM01010789    JXUM01010790    JXUM01010791    JXUM01069333    JXUM01069334    JXUM01069335    GAPW01002918    KQ562547    KQ560317    JAC10680.1    KXJ75646.1    KXJ83082.1    GECZ01032252    JAS37517.1    CH478616    EAT32713.1    KZ288222    PBC32085.1    GFDL01000135    JAV34910.1    KK852652    KDR19404.1    GECU01000728    JAT06979.1    GECZ01011954    JAS57815.1    GEBQ01020498    JAT19479.1    AJWK01007642    KOC68917.1    NEVH01009772    PNF32667.1    KQ434856    KZC08759.1    UFQT01000065    SSX19299.1    PNF32665.1    GAMC01003780    JAC02776.1    GDHC01007855    JAQ10774.1    KK107672    EZA48149.1    RLU19340.1    GAHY01002077    JAA75433.1    AXCN02001479    GAKP01010864    JAC48088.1    ACPB03020876    GBHO01020566    GBRD01011226    GBRD01011224    GBRD01004872    GBRD01004868    JAG23038.1    JAG54598.1    ODYU01012860    SOQ59369.1    GDHF01010979    JAI41335.1    AK402677    BAM19299.1    NWSH01000035    PCG80446.1    AGBW02008295    OWR53807.1    GDHF01007513    JAI44801.1    CH477188    EAT48780.1    JXUM01102377    KQ564723    KXJ71832.1   

Proteomes

UP000218220    UP000283053    UP000053240    UP000053268    UP000007151    UP000192223    + More
UP000008820    UP000075886    UP000069272    UP000075881    UP000075884    UP000000673    UP000075882    UP000075840    UP000075885    UP000076407    UP000075902    UP000075903    UP000007062    UP000069940    UP000249989    UP000030765    UP000075883    UP000092462    UP000092461    UP000183832    UP000002320    UP000075900    UP000075920    UP000079169    UP000002358    UP000076408    UP000007266    UP000005203    UP000053825    UP000279307    UP000075901    UP000075880    UP000242457    UP000027135    UP000235965    UP000076502    UP000053097    UP000015103   

Pfam

PF01151   ELO

Interpro

IPR002076   ELO_fam        + More
IPR030457   ELO_CS       

ProteinModelPortal

A0A2A4IXM8   A0A2H1X404   A0A3S2LZE4   A0A194REI7   A0A194PXS6   A0A212EGR1   + More
A0A1W4X4I0   A0A1S4FIU2   Q16ZG9   A0A182QU28   A0A182FG76   A0A182JTP0   A0A182NKP9   W5J681   A0A182KQS6   A0A182I2U4   A0A182P229   A0A182XLN3   A0A182UI04   A0A182UUZ5   Q5TWT4   A0A182GM29   A0A084VQU4   A0A1Q3FPY2   A0A182LV12   A0A1B0D2D9   A0A1B0CDB2   A0A0C9QVK2   A0A1W4WV14   A0A1J1HH34   B0W3U8   A0A182G240   A0A182RTX0   A0A182WJN4   A0A1S3D6M0   K7J7X7   A0A182YMP4   A0A1B6CQ89   D6X2U6   A0A182F0V7   A0A088ARV5   A0A0L7RDM4   A0A182M983   A0A182NB63   A0A182QAU9   A0A182PW57   A0A182VTN0   A0A182IB52   A0A182VEV3   A0A182TLQ9   A0A182LJX9   Q7PPN4   A0A182X629   A0A1Y1KWU6   A0A182K6I1   A0A3L8DHL5   A0A182Y8I0   W5J4Z1   A0A084VMS9   A0A088ARL4   A0A182T880   Q17HH4   A0A0A1XAY8   A0A023EP01   A0A1B6EHW1   Q16EQ4   A0A182ISK0   A0A2A3EJY7   A0A1Q3G529   A0A067R7E0   A0A182RA82   A0A1B6K697   A0A1B6G5V2   A0A1B6L6Z1   A0A1B0CDB4   A0A0L7RD74   A0A2J7QVQ5   A0A154PA26   A0A336LRW1   A0A1S3D216   A0A2J7QVP9   W8BNS1   A0A146LSJ0   A0A026VZ79   R4G7V2   A0A182Q8T4   A0A034W2T7   T1IE92   A0A0A9XVZ3   A0A1B0D2E0   A0A2H1X230   A0A0K8VS01   I4DN09   A0A2A4K8W8   A0A212FJ78   A0A0K8W144   Q17Q14   A0A182H129  

KEGG

105841414    K10249 elongation of very long chain fatty acids protein 4 [EC:2.3.1.199] | (RefSeq) elongation of v

PATHWAY

00062    Fatty acid elongation - Bombyx mori (domestic silkworm)
01040    Biosynthesis of unsaturated fatty acids - Bombyx mori (domestic silkworm)
01100    Metabolic pathways - Bombyx mori (domestic silkworm)
01212    Fatty acid metabolism - Bombyx mori (domestic silkworm)

GO

GO:0102336   GO:0102337   GO:0006633   GO:0102756   GO:0102338   GO:0016021   GO:0034626   GO:0009922   GO:0042761   GO:0019367   GO:0030148   GO:0030176   GO:0034625   GO:0006508   GO:0007017   GO:0005200   GO:0005525   GO:0031386   GO:0048869   GO:0003676   GO:0016491   GO:0015930  

PANTHER

PTHR11157  

Length:

353

Number of predicted TMHs:

6

Exp number of AAs in TMHs:

144.7864

Exp number, first 60 AAs:

18.574

Total prob of N-in:

0.09212

POSSIBLE N-term signal

sequence

inside

1  -  66

TMhelix

67  -  89

outside

90  -  111

TMhelix

112  -  134

inside

135  -  140

TMhelix

141  -  159

outside

160  -  168

TMhelix

169  -  191

inside

192  -  203

TMhelix

204  -  223

outside

224  -  237

TMhelix

238  -  255

inside

256  -  353

 

 

Pi

237.816951

Theta

165.056783

Tajima's D

1.575277

CLR

0.020699

CSRT

0.803009849507525

Interpretation

Uncertain