Gene

KWMTBOMO13318

Pre Gene Modal

BGIBMGA004686

Annotation

LMBR1_domain-containing_protein_2-like_protein_[Danaus_plexippus]

Location

Bomo_Chr22(-):13526813-13540962      View in EpiBrowser

Full name

LMBR1 domain-containing protein 2 homolog      

Location in the cell

PlasmaMembrane   Reliability : 4.648

CDS

ATGGTTTACACGTTGTTCGTGGTCGAAATAATATCGGCGTTCGTGCTCGCCGCGACGCTTTTGTACCGATATGGAGATTGTTATAGAAATCACATATTGGTGACAGTATCAGTGCTAACAGCATGGTACTTTTCTTTTGTTATTATGTTCCTCTTGCCATTGGACGTGACGTCGACCGTTTACCGTCAATGTCTAGAAGATAACTCCACAATTGCAATAGCAGAAAGAGCTGTAATTAACAATGTATCATCTACAACAACTCCGCCCATTGTGCCATGTCAGGAACCTTGGAGCTATGTACATAAGGAAGTTTTTACTAATCTGTGGAGGGTTGTTTATTGGACATCACAATGTCTGACTTGGTTAATAATGCCGATGATGCAGTCGTACAGTAAAGCAGGTGACTTTACAGTGAAAGGAAAACTAAAATCTGCATTAGTTGACAATGCCATATACTATGGCTCGTACCTACTGATATGTGGCATTCTCCTCATATACATTGCCTTGAAACCGGGTGTATCATTAGACGGTGCGAAAATAAAAGCAATAGCTTCATCTGCAAGTAACACTTGGGGTCTATTTTTATTGATTTTGTTACTAGGATATGCTTTAGTTGAAGTACCAAGAAATTTATGGAATAACTCAAAAAAGAATTATACATTGACATACAGTTATTTCAAAATAGCAAAACTTAGTACTGACAAGTGCGAAGCTGAGGAAACTGTAGATGACATATTAGATAGTTTAAGTGCAATAACGGCGGCCGTGGGTCCGGGGCATCCTCTGCACCGCCACGTGGAGACCATCGTGCAGAAGCTCCCTGTACAGCTGCGCGACCGGATGACGTCACGCCCACCGCCCGAGCGCCCCGCCTCGCCCTCCCTCAAGTCTCTAGTCAATTTGCATAAAAAGACAATCAAAGCGCTTCACGTCCTCCAACGGACGGAGACCCAGTGGGGCCTGTCACTGGAACGTATATTCCACCTGGAGGACGTGGCCTCCAACCAGCGCCTGCCAGACAGGAGATTCCAACATTTCTTTCCCACACCACGACCGAAACTACAGCGAATATTGTACCCGCCCATTTTAGAATGGTACTGGGAGTGCTTCCTCAAGCAATATTTCCTTAAGGGCATGGCAATAATCACCGGCATAATGTCCGTGGCGGTGGTCTGGTCCGAAATGACGTTCTTCTGCAAGAAACCAGTCCTGTCAGTGTTCGCTAACGTGGTCATAGCAGCTGGAGAGACTTATAACTATGCAGCTATTGTGACAATATCGACCGTAGTGATAGCGTACATGTTCTACTGCGCGTACTCCACGGTGCTGAAGATCAGACTGCTGAACTTGTATTACCTGGCGCCTCATCATCAGACTAACGAATACAGTTTGATATTCTCCGGAATGATGGTCTGCAGGCTAACGCCGGCCATGTGCTTGAACTTTCTAAGTCTGATCCATATGGATTCTCATGTTATTAAGGAAAGAGTCATGGAAACTTCATATACACAGATAATGGGTCACATGGACGTATTGGGCATCATAGCGGAGGGCTTCAACATTTACTTCCCCATGTTGGTGGTGTTGCTGTGCCTGGCGACGTACCTGTCCCTCGGCAGCCGCGTCCTCACGCTGTGCGGCTTCCAGCAGTTCGTGGGGGACGATGAGCTAACAACGGATCTGGTGGATGAAGGAAGGGAGATCGTGAAGCGAGAAAAACGCAAGCGGCAACGCGCCGAGGAGTCCATGAGCCGACGACGCGACTACAGCGAGAGGTTCACGAAGTACCGCACCAACAGGGACACCAATGATGGAGCCCGCACTGGGCTGCTGCACGACGTGGACACAGAGTACTACGCGGGGCCGGACCGCAGCAGCGCCGCCGTGCCGGACTACGAGCGCGCGGAGATGCCCTACAACCGCTCCGACTTGACGCTGGAAGACGAGATCGAGCATCGGTTCGGGGACAGCGCCCTGCCGACTGTGCGAACCGAGTACGACGGTAGGCGGGATAAAATGACAATGCCTCCCAGGGGCTTGTTTGACGATGTTTAA

Protein

MVYTLFVVEIISAFVLAATLLYRYGDCYRNHILVTVSVLTAWYFSFVIMFLLPLDVTSTVYRQCLEDNSTIAIAERAVINNVSSTTTPPIVPCQEPWSYVHKEVFTNLWRVVYWTSQCLTWLIMPMMQSYSKAGDFTVKGKLKSALVDNAIYYGSYLLICGILLIYIALKPGVSLDGAKIKAIASSASNTWGLFLLILLLGYALVEVPRNLWNNSKKNYTLTYSYFKIAKLSTDKCEAEETVDDILDSLSAITAAVGPGHPLHRHVETIVQKLPVQLRDRMTSRPPPERPASPSLKSLVNLHKKTIKALHVLQRTETQWGLSLERIFHLEDVASNQRLPDRRFQHFFPTPRPKLQRILYPPILEWYWECFLKQYFLKGMAIITGIMSVAVVWSEMTFFCKKPVLSVFANVVIAAGETYNYAAIVTISTVVIAYMFYCAYSTVLKIRLLNLYYLAPHHQTNEYSLIFSGMMVCRLTPAMCLNFLSLIHMDSHVIKERVMETSYTQIMGHMDVLGIIAEGFNIYFPMLVVLLCLATYLSLGSRVLTLCGFQQFVGDDELTTDLVDEGREIVKREKRKRQRAEESMSRRRDYSERFTKYRTNRDTNDGARTGLLHDVDTEYYAGPDRSSAAVPDYERAEMPYNRSDLTLEDEIEHRFGDSALPTVRTEYDGRRDKMTMPPRGLFDDV

Similarity

Belongs to the LIMR family.
Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.

Keywords

Coiled coil   Complete proteome   Glycoprotein   Membrane   Reference proteome   Transmembrane   Transmembrane helix  

Feature

chain  LMBR1 domain-containing protein 2 homolog

Uniprot

H9J596   A0A1E1W671   A0A2A4J9W2   A0A2A4JAT3   A0A1E1WQ97   A0A2A4JBE8   + More
A0A2W1BIF3   A0A212FFD6   A0A194PYF0   A0A151WH03   A0A195DCV2   A0A158NS38   A0A195BCD7   A0A195FWG4   F4WJT5   E9IFN2   A0A195BZQ4   A0A310S8R6   A0A026W6A3   E2A7S2   E2BPT8   A0A154PFX1   A0A2A3E3R2   V9IEP2   A0A088ALU8   A0A1W4WIQ6   D6X0Q3   A0A1Y1L8F3   A0A2J7QVZ7   A0A0L7LGM7   A0A067R9M0   B3NZS8   B4PUN1   B4HKE2   B4QWM9   H5V8C9   Q8MRQ4   B4GP58   Q29BL9   A0A0M4EGW5   A0A3B0K6C7   B4K4Z4   A0A1W4W3K9   A0A1A9WY80   A0A1A9Z8D5   A0A1A9UYZ0   E0VEJ2   A0A1B0GEX5   B4JEL2   A0A1B0BB91   A0A1A9YFB2   A0A0C9QIN8   B4N8W2   A0A336MGB9   A0A336MFI0   B3M061   U5EYB4   A0A182FT45   A0A084WRD1   A0A2M4DMC2   A0A2M4DMB8   B4LW16   A0A0P4VV95   A0A2M4BEM7   A0A2M4BFJ5   A0A182QJJ4   A0A1I8Q0Z9   A0A182IKT8   W8C1P1   A0A224XL42   A0A1B6CP33   A0A034WHD1   A0A182PAE8   A0A2M4AC79   A0A182XI12   B0WAG8   A0A182VL53   A0A182XWW7   A0A182LF22   A0A182TYX7   A0A182HSZ3   Q7QC62   Q178R5   A0A182R360   A0A182JRI3   A0A0K8TM10   A0A182M2H5   A0A182NLB4   A0A1Q3FCH8   A0A0A1WWU2   A0A182VXD9   A0A1I8N4D3   A0A0A1WSE2   A0A1B6KRT3   A0A0N8ES51   A0A1B6H6Q1   T1HXA6   A0A1W7R572   A0A1J1HKC4  

Pubmed

19121390    28756777    22118469    26354079    21347285    21719571    + More
21282665    24508170    30249741    20798317    18362917    19820115    28004739    26227816    24845553    17994087    17550304    10731132    12537572    12537569    15632085    20566863    24438588    27129103    24495485    25348373    25244985    20966253    12364791    14747013    17210077    17510324    26369729    25830018    25315136    26999592   

EMBL

BABH01039719    BABH01039720    BABH01039721    GDQN01008615    JAT82439.1    NWSH01002228    + More
PCG68875.1    PCG68876.1    GDQN01001831    JAT89223.1    PCG68874.1    KZ150103    PZC73485.1    AGBW02008829    OWR52442.1    KQ459586    KPI98053.1    KQ983136    KYQ47085.1    KQ980989    KYN10711.1    ADTU01024459    ADTU01024460    KQ976528    KYM81864.1    KQ981208    KYN44657.1    GL888186    EGI65577.1    GL762880    EFZ20615.1    KQ978457    KYM93820.1    KQ763867    OAD54681.1    KK107374    QOIP01000010    EZA51597.1    RLU18105.1    GL437382    EFN70540.1    GL449658    EFN82289.1    KQ434896    KZC10741.1    KZ288391    PBC26355.1    JR040387    AEY59112.1    KQ971371    EFA09996.1    GEZM01066474    JAV67856.1    NEVH01009770    PNF32746.1    JTDY01001262    KOB74351.1    KK852801    KDR16315.1    CH954181    EDV49788.1    CM000160    EDW96648.1    CH480815    EDW42892.1    CM000364    EDX13633.1    BT133230    AFA36413.1    AE014297    AY119474    CH479186    EDW38941.1    CM000070    CP012526    ALC47691.1    OUUW01000005    SPP81176.1    CH933806    EDW13965.1    DS235092    EEB11798.1    CCAG010012612    CH916369    EDV93143.1    JXJN01011342    GBYB01003379    JAG73146.1    CH964232    EDW81563.1    UFQT01000546    SSX25128.1    UFQT01001139    SSX29114.1    CH902617    EDV42018.1    GANO01000466    JAB59405.1    ATLV01026020    KE525405    KFB52775.1    GGFL01014525    MBW78703.1    GGFL01014526    MBW78704.1    CH940650    EDW66521.1    GDKW01000629    JAI55966.1    GGFJ01002353    MBW51494.1    GGFJ01002684    MBW51825.1    AXCN02000116    GAMC01000829    GAMC01000828    JAC05728.1    GFTR01007563    JAW08863.1    GEDC01022088    GEDC01017181    GEDC01011302    GEDC01009321    JAS15210.1    JAS20117.1    JAS25996.1    JAS27977.1    GAKP01003956    JAC54996.1    GGFK01005066    MBW38387.1    DS231872    EDS41391.1    APCN01000376    AAAB01008859    EAA08172.2    CH477360    EAT42676.1    GDAI01002209    JAI15394.1    AXCM01000493    GFDL01009833    JAV25212.1    GBXI01011419    JAD02873.1    GBXI01012979    JAD01313.1    GEBQ01025829    GEBQ01025714    JAT14148.1    JAT14263.1    GDUN01000442    JAN95477.1    GECU01037383    JAS70323.1    ACPB03011002    GEHC01001329    JAV46316.1    CVRI01000008    CRK88503.1   

Proteomes

UP000005204    UP000218220    UP000007151    UP000053268    UP000075809    UP000078492    + More
UP000005205    UP000078540    UP000078541    UP000007755    UP000078542    UP000053097    UP000279307    UP000000311    UP000008237    UP000076502    UP000242457    UP000005203    UP000192223    UP000007266    UP000235965    UP000037510    UP000027135    UP000008711    UP000002282    UP000001292    UP000000304    UP000000803    UP000008744    UP000001819    UP000092553    UP000268350    UP000009192    UP000192221    UP000091820    UP000092445    UP000078200    UP000009046    UP000092444    UP000001070    UP000092460    UP000092443    UP000007798    UP000007801    UP000069272    UP000030765    UP000008792    UP000075886    UP000095300    UP000075880    UP000075885    UP000076407    UP000002320    UP000075903    UP000076408    UP000075882    UP000075902    UP000075840    UP000007062    UP000008820    UP000075900    UP000075881    UP000075883    UP000075884    UP000075920    UP000095301    UP000015103    UP000183832   

PRIDE

H9J596    H5V8C9    Q8MRQ4   

Pfam

PF04791   LMBR1        + More
PF14777   BBIP10
PF07885   Ion_trans_2
PF00210   Ferritin
PF13855   LRR_8
PF13306   LRR_5

Interpro

IPR006876   LMBR1-like_membr_prot        + More
IPR028233   BBIP10       
IPR003092   2pore_dom_K_chnl_TASK       
IPR013099   K_chnl_dom       
IPR003280   2pore_dom_K_chnl       
IPR012347   Ferritin-like       
IPR008331   Ferritin_DPS_dom       
IPR009078   Ferritin-like_SF       
IPR009040   Ferritin-like_diiron       
IPR026906   LRR_5       
IPR001611   Leu-rich_rpt       
IPR003591   Leu-rich_rpt_typical-subtyp       
IPR032675   LRR_dom_sf       

SUPFAM

SSF47240   SSF47240       

Gene 3D

1.20.1260.10     3.80.10.10    

ProteinModelPortal

H9J596   A0A1E1W671   A0A2A4J9W2   A0A2A4JAT3   A0A1E1WQ97   A0A2A4JBE8   + More
A0A2W1BIF3   A0A212FFD6   A0A194PYF0   A0A151WH03   A0A195DCV2   A0A158NS38   A0A195BCD7   A0A195FWG4   F4WJT5   E9IFN2   A0A195BZQ4   A0A310S8R6   A0A026W6A3   E2A7S2   E2BPT8   A0A154PFX1   A0A2A3E3R2   V9IEP2   A0A088ALU8   A0A1W4WIQ6   D6X0Q3   A0A1Y1L8F3   A0A2J7QVZ7   A0A0L7LGM7   A0A067R9M0   B3NZS8   B4PUN1   B4HKE2   B4QWM9   H5V8C9   Q8MRQ4   B4GP58   Q29BL9   A0A0M4EGW5   A0A3B0K6C7   B4K4Z4   A0A1W4W3K9   A0A1A9WY80   A0A1A9Z8D5   A0A1A9UYZ0   E0VEJ2   A0A1B0GEX5   B4JEL2   A0A1B0BB91   A0A1A9YFB2   A0A0C9QIN8   B4N8W2   A0A336MGB9   A0A336MFI0   B3M061   U5EYB4   A0A182FT45   A0A084WRD1   A0A2M4DMC2   A0A2M4DMB8   B4LW16   A0A0P4VV95   A0A2M4BEM7   A0A2M4BFJ5   A0A182QJJ4   A0A1I8Q0Z9   A0A182IKT8   W8C1P1   A0A224XL42   A0A1B6CP33   A0A034WHD1   A0A182PAE8   A0A2M4AC79   A0A182XI12   B0WAG8   A0A182VL53   A0A182XWW7   A0A182LF22   A0A182TYX7   A0A182HSZ3   Q7QC62   Q178R5   A0A182R360   A0A182JRI3   A0A0K8TM10   A0A182M2H5   A0A182NLB4   A0A1Q3FCH8   A0A0A1WWU2   A0A182VXD9   A0A1I8N4D3   A0A0A1WSE2   A0A1B6KRT3   A0A0N8ES51   A0A1B6H6Q1   T1HXA6   A0A1W7R572   A0A1J1HKC4  

KEGG

101743503    no KO assigned | (RefSeq) LMBR1 domain-containing protein 2 homolog

GO

GO:0016021   GO:0034464   GO:0060271   GO:0005267   GO:0006879   GO:0005623   GO:0008199  

Subcellular location

Membrane  

Length:

684

Number of predicted TMHs:

8

Exp number of AAs in TMHs:

175.48528

Exp number, first 60 AAs:

41.89903

Total prob of N-in:

0.83157

POSSIBLE N-term signal

sequence

inside

1  -  4

TMhelix

5  -  22

outside

23  -  31

TMhelix

32  -  54

inside

55  -  148

TMhelix

149  -  168

outside

169  -  182

TMhelix

183  -  205

inside

206  -  373

TMhelix

374  -  396

outside

397  -  420

TMhelix

421  -  443

inside

444  -  463

TMhelix

464  -  486

outside

487  -  510

TMhelix

511  -  533

inside

534  -  684

 

 

Pi

245.376048

Theta

155.147534

Tajima's D

1.28439

CLR

0

CSRT

0.735513224338783

Interpretation

Uncertain