Gene

KWMTBOMO13302

Pre Gene Modal

BGIBMGA004702

Annotation

PREDICTED:_transmembrane_protein_35_isoform_X2_[Papilio_xuthus]

Location

Bomo_Chr22(-):13110978-13120650      View in EpiBrowser

Full name

NADH-cytochrome b5 reductase      

Location in the cell

PlasmaMembrane   Reliability : 1.908

CDS

ATGATATCGAAAGAATTGCATAAGGATTTGAGAAAGGAGTATGTTAGATATGCAAAAGTATTTCCACTGACTGATACGTTGGACTTCAAATTACCATCGAAATGGTACAGGAGGACCGTGGGTGGTTTAGAAATATTATTTGGGTTAGCGTTGGCAGTTGCACCTAATCATAAGTTGAAGAACGCCGCGAACATCGGTCTGGTGTTGCTAATGATCCTGGCGGCGTACTCTCACGTGATGGTGGGCGACCCGTTCGACCGATGTGCGCCGGCTCTCGTATTCTTTTTCATGCTCAGTGGGAGGCTCGTCGTTTGGTATCAGACGAGTCGACGTGAACAGCTAGAGAAGTCCGCCACAGCCCAGAACGGCAACGGACTAAAGAGGGATTAA

Protein

MISKELHKDLRKEYVRYAKVFPLTDTLDFKLPSKWYRRTVGGLEILFGLALAVAPNHKLKNAANIGLVLLMILAAYSHVMVGDPFDRCAPALVFFFMLSGRLVVWYQTSRREQLEKSATAQNGNGLKRD

Catalytic Activity

2 [Fe(III)-cytochrome b5] + NADH = 2 [Fe(II)-cytochrome b5] + H(+) + NAD(+)

Cofactor

FAD

Similarity

Belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.

Uniprot

A0A194PXE3   A0A212F0N4   A0A194R0N4   A0A2H1VWW1   A0A2W1BID4   H9J5B2   + More
A0A023EH56   A0A182RSQ0   A0A1Q3FZK6   A0A182WJ68   A0A336LU73   Q7PT42   A0A182KRD5   A0A182Q2J9   A0A182ITK3   A0A182XYX9   T1EA69   Q16W86   A0A0L0C7H7   A0A034VRC8   A0A0C9R1P8   A0A0K8UA00   A0A182NHT8   B4N712   A0A1L8DA13   A0A1I8PR35   B3M7R9   B4PDR0   A0A0A1XHW1   A0A182UFU8   B3NES7   N6ULU9   A0A084WNC5   A0A1W4VV60   E9IK90   A0A182UZY9   A0A182KES5   A0A182PQD5   A0A182I3C5   B4H3G3   Q2LZP8   A0A182X3P4   A0A3B0JUD0   B4HVX2   B4QMH9   Q8T0T9   A0A139WI43   A0A1Y1K1H0   A0A1I8MBB6   A0A151JA11   A0A1B0FM45   A0A1A9Y9M3   A0A1A9VYK9   A0A1B0B9A0   A0A1A9Z3D5   W5JAN0   A0A182FF60   A0A0L7LTG0   T1I5P7   A0A067QQZ6   A0A023F9R2   E0W343   B4L974   R4G5E4   A0A0M3QWM3   A0A2A3E3D9   A0A0A9XZL1   A0A088A6Z7   V9ICU9   A0A195CSX8   A0A146KQV3   B4LBT9   A0A310SBE3   A0A154P7G6   A0A0M8ZNB0   E2BUW8   A0A195BX10   A0A158P3M8   A0A026WUE9   A0A0L7R561   E2AJ43   A0A195F192   B4J1X4   A0A1A9X2W2   A0A0K8TLH2   A0A1B6IW00   A0A1B6FDR1   A0A0T6BGG1   K7ITS8   A0A1B6E1Y9   D6WJE9   A0A1B0DPS7   A0A1B0CBS9   A0A182M9S9   A0A2H8TTE1   J9K3Z3   C4WTP6   A0A1D2MNR0   A0A2P2IAE9   A0A2R7WLI4  

EC Number

1.6.2.2

Pubmed

26354079    22118469    28756777    19121390    24945155    12364791    + More
14747013    17210077    20966253    25244985    17510324    26108605    25348373    17994087    17550304    25830018    23537049    24438588    21282665    15632085    23185243    22936249    10731132    12537568    12537572    12537573    12537574    16110336    17569856    17569867    26109357    26109356    18362917    19820115    28004739    25315136    20920257    23761445    26227816    24845553    25474469    20566863    25401762    26823975    20798317    21347285    24508170    30249741    26369729    20075255    27289101   

EMBL

KQ459586    KPI98016.1    AGBW02011073    OWR47261.1    KQ460883    KPJ11262.1    + More
ODYU01004946    SOQ45337.1    KZ150103    PZC73465.1    BABH01037020    GAPW01005393    JAC08205.1    GFDL01002057    JAV32988.1    UFQS01000127    UFQT01000127    SSX00161.1    SSX20541.1    AAAB01008807    EAA04565.5    AXCN02000377    GAMD01000697    JAB00894.1    CH477572    EAT38864.1    JRES01000810    KNC28201.1    GAKP01014844    JAC44108.1    GBYB01000761    JAG70528.1    GDHF01028906    GDHF01022416    GDHF01011113    JAI23408.1    JAI29898.1    JAI41201.1    CH964168    EDW80151.1    GFDF01010914    JAV03170.1    CH902618    EDV38792.1    CM000159    EDW92875.1    GBXI01004199    JAD10093.1    CH954178    EDV50200.1    APGK01027575    APGK01027576    APGK01027577    APGK01027578    APGK01027579    KB740664    KB631791    ENN79682.1    ERL86099.1    ATLV01024587    KE525352    KFB51719.1    GL763924    EFZ19021.1    APCN01000205    CH479206    EDW30903.1    CH379069    EAL29459.2    KRT08027.1    OUUW01000002    SPP76966.1    CH480817    EDW50087.1    CM000363    CM002912    EDX08836.1    KMY96903.1    AE014296    AY069059    AAF47539.2    AAL39204.1    AHN57927.1    KQ971342    KYB27569.1    GEZM01101393    JAV52667.1    KQ979347    KYN21874.1    CCAG010023908    CCAG010023909    JXJN01010337    ADMH02001806    ETN61056.1    JTDY01000159    KOB78531.1    ACPB03017241    KK853069    KDR11826.1    GBBI01000582    JAC18130.1    DS235882    EEB20049.1    CH933816    EDW17249.1    GAHY01000041    JAA77469.1    CP012525    ALC44399.1    KZ288432    PBC25812.1    GBHO01018245    JAG25359.1    JR040074    AEY58968.1    KQ977304    KYN03801.1    GDHC01020240    JAP98388.1    CH940647    EDW68716.1    KQ761783    OAD57057.1    KQ434831    KZC07812.1    KQ435989    KOX67715.1    GL450772    EFN80505.1    KQ976394    KYM93169.1    ADTU01008269    ADTU01008270    KK107119    QOIP01000009    EZA58734.1    RLU18380.1    KQ414654    KOC65891.1    GL439967    EFN66483.1    KQ981880    KYN33937.1    CH916366    EDV95899.1    GDAI01002597    JAI15006.1    GECU01016585    GECU01012688    JAS91121.1    JAS95018.1    GECZ01021441    GECZ01019659    JAS48328.1    JAS50110.1    LJIG01000521    KRT86419.1    GEDC01005352    JAS31946.1    EFA03684.2    AJVK01008234    AJWK01005810    AJWK01005811    AJWK01005812    AJWK01005813    AXCM01022306    GFXV01005709    MBW17514.1    ABLF02038860    AK340708    BAH71266.1    LJIJ01000801    ODM94485.1    IACF01005413    LAB70998.1    KK855041    PTY20472.1   

Proteomes

UP000053268    UP000007151    UP000053240    UP000005204    UP000075900    UP000075920    + More
UP000007062    UP000075882    UP000075886    UP000075880    UP000076408    UP000008820    UP000037069    UP000075884    UP000007798    UP000095300    UP000007801    UP000002282    UP000075902    UP000008711    UP000019118    UP000030742    UP000030765    UP000192221    UP000075903    UP000075881    UP000075885    UP000075840    UP000008744    UP000001819    UP000076407    UP000268350    UP000001292    UP000000304    UP000000803    UP000007266    UP000095301    UP000078492    UP000092444    UP000092443    UP000078200    UP000092460    UP000092445    UP000000673    UP000069272    UP000037510    UP000015103    UP000027135    UP000009046    UP000009192    UP000092553    UP000242457    UP000005203    UP000078542    UP000008792    UP000076502    UP000053105    UP000008237    UP000078540    UP000005205    UP000053097    UP000279307    UP000053825    UP000000311    UP000078541    UP000001070    UP000091820    UP000002358    UP000092462    UP000092461    UP000075883    UP000007819    UP000094527   

PRIDE

H9J5B2    Q8T0T9   

Pfam

PF13564   DoxX_2        + More
PF00970   FAD_binding_6
PF00175   NAD_binding_1
PF09791   Oxidored-like

Interpro

IPR029693   TMEM35A        + More
IPR040399   TM35A/B       
IPR032808   DoxX       
IPR019180   Oxidoreductase-like_N       
IPR008333   Cbr1-like_FAD-bd_dom       
IPR039261   FNR_nucleotide-bd       
IPR001834   CBR-like       
IPR017938   Riboflavin_synthase-like_b-brl       
IPR001433   OxRdtase_FAD/NAD-bd       
IPR017927   FAD-bd_FR_type       
IPR001709   Flavoprot_Pyr_Nucl_cyt_Rdtase       

SUPFAM

SSF63380   SSF63380        + More
SSF52343   SSF52343       

Gene 3D

3.40.50.80    

ProteinModelPortal

A0A194PXE3   A0A212F0N4   A0A194R0N4   A0A2H1VWW1   A0A2W1BID4   H9J5B2   + More
A0A023EH56   A0A182RSQ0   A0A1Q3FZK6   A0A182WJ68   A0A336LU73   Q7PT42   A0A182KRD5   A0A182Q2J9   A0A182ITK3   A0A182XYX9   T1EA69   Q16W86   A0A0L0C7H7   A0A034VRC8   A0A0C9R1P8   A0A0K8UA00   A0A182NHT8   B4N712   A0A1L8DA13   A0A1I8PR35   B3M7R9   B4PDR0   A0A0A1XHW1   A0A182UFU8   B3NES7   N6ULU9   A0A084WNC5   A0A1W4VV60   E9IK90   A0A182UZY9   A0A182KES5   A0A182PQD5   A0A182I3C5   B4H3G3   Q2LZP8   A0A182X3P4   A0A3B0JUD0   B4HVX2   B4QMH9   Q8T0T9   A0A139WI43   A0A1Y1K1H0   A0A1I8MBB6   A0A151JA11   A0A1B0FM45   A0A1A9Y9M3   A0A1A9VYK9   A0A1B0B9A0   A0A1A9Z3D5   W5JAN0   A0A182FF60   A0A0L7LTG0   T1I5P7   A0A067QQZ6   A0A023F9R2   E0W343   B4L974   R4G5E4   A0A0M3QWM3   A0A2A3E3D9   A0A0A9XZL1   A0A088A6Z7   V9ICU9   A0A195CSX8   A0A146KQV3   B4LBT9   A0A310SBE3   A0A154P7G6   A0A0M8ZNB0   E2BUW8   A0A195BX10   A0A158P3M8   A0A026WUE9   A0A0L7R561   E2AJ43   A0A195F192   B4J1X4   A0A1A9X2W2   A0A0K8TLH2   A0A1B6IW00   A0A1B6FDR1   A0A0T6BGG1   K7ITS8   A0A1B6E1Y9   D6WJE9   A0A1B0DPS7   A0A1B0CBS9   A0A182M9S9   A0A2H8TTE1   J9K3Z3   C4WTP6   A0A1D2MNR0   A0A2P2IAE9   A0A2R7WLI4  

KEGG

101740729    no KO assigned | (RefSeq) transmembrane protein 35

GO

GO:0016021   GO:0004128  

PANTHER

PTHR13163   PTHR13163:SF0  

Length:

129

Number of predicted TMHs:

2

Exp number of AAs in TMHs:

50.53488

Exp number, first 60 AAs:

13.70809

Total prob of N-in:

0.31712

POSSIBLE N-term signal

sequence

inside

1  -  61

TMhelix

62  -  79

outside

80  -  88

TMhelix

89  -  106

inside

107  -  129

 

 

Pi

55.881718

Theta

18.501586

Tajima's D

-1.642877

CLR

4.688937

CSRT

0.0425478726063697

Interpretation

Uncertain