Gene

KWMTBOMO13292

Pre Gene Modal

BGIBMGA004708

Annotation

lipase_3-like_precursor_protein_[Antheraea_pernyi]

Location

Bomo_Chr22(-):12961668-12963400      View in EpiBrowser

Full name

Lipase      

Location in the cell

PlasmaMembrane   Reliability : 1.26

CDS

ATGAGATTGCAGTGTGTATTATTAGTTTTCGTATTACTACAATTCGGAGTTATCGATTGTAGATACGTTTCTTGGTTGCCTGACGTTTTGGGCACTGTCACCAACAAAACAACTCAATTAACGAATTATGTTCGAGAAAAGGGCCGCAGCATAAAACATTTCTACGTAGAAAATGTACGAAATAAGATAACGTCGTACTTCGGAATTAACAATAAAGATGAATCGGAGTATTCTGGGGATGATAAGCAATTGGAGTACAAATGTTCGGACGACGATCCATCGATTTTGATGACCACTCCACAACTGATAGCTCTTCATGGATACTCAGCGGAGTCGCACACAGTGGTTACTGATGATGGATACATTTTGACTGTGCACAGAATACCTTATCCGAAGAAAATCACCAACAGAATTATCCCCAGGAAGACTGTGTTACTTCATCACGGACTCCTCGGTAGCTCGGCCGATTGGATCATAGCTGGACCAGAAAAGGGCCTTGGCTACATATTATCTGACGCCGGATATGACGTTTGGCTGGCTAATGTTCGAGGTAACACTTACTCTCGAGCTCACGTCTCACGGCCCTCTGATTCATTCGCATTCTGGAACTTTACATTCCACGACGTTAGTCAACACGATCTACCTGCTGTTATCGACTACATAATGGATGTAAAGGGATGGGACGCCAAAGTTAACTATGTTGGTCATTCAATGGGCACCACTATATTGTTCGCCCTACTTTCCACAAAAACGCAATATAATAAAATTTTAAGGGCCGGTTATGCTTTAGCGCCAGTCGCCTACATGTCTGATATAAAAAGTCCGATTCGTTTACTAGCAAAATTTAGTAACAATATTGAATTTTTAATGAAACTTTTGGGTGCAAATGAATTTCTCCCTCAAAATGCCGTTTTGCGTTGGTTATCGAAAAAGGCTTGTGAGATTAATAATTTCGAAGAGGCGATCTGTGAAAACTCCCTGTTTGTGTTATGCGGCCACGACGAAAAACAATTTAACAGATCTTTGCTGCCAATTATATTGGGTCACGTTCCCGCCGGCGCATCAACAAAGACGCTTGTTCATTACGCACAGGAAATACGGAACAAGGGTCGATTTCAACAATTTGATTACGGAGCAGAAGGCAACTATAAAGAGTATGGTACCGAAACTCCACCTGAGTATCCTCTGCACAAAGTGACACTGCCTATTGCTTTATTAAGCTCTCAAAATGACTGGCTAGCTGGCGACGCGGACGTAGTAAACTTATATGATCAGTTATCAAATCCTATAGAACATTATGTTGTGCCATTGAAAGAGTTTAACCATATTGATTTTCTGTGGGCTAAAGATGCCCCGAAACTTGTGTATGCAAAACTTCTGCAGTTATTAGAAGAAGGTGTAAGTAATAACTATAATATGGACATAGAGAACGCTATAATTTAA

Protein

MRLQCVLLVFVLLQFGVIDCRYVSWLPDVLGTVTNKTTQLTNYVREKGRSIKHFYVENVRNKITSYFGINNKDESEYSGDDKQLEYKCSDDDPSILMTTPQLIALHGYSAESHTVVTDDGYILTVHRIPYPKKITNRIIPRKTVLLHHGLLGSSADWIIAGPEKGLGYILSDAGYDVWLANVRGNTYSRAHVSRPSDSFAFWNFTFHDVSQHDLPAVIDYIMDVKGWDAKVNYVGHSMGTTILFALLSTKTQYNKILRAGYALAPVAYMSDIKSPIRLLAKFSNNIEFLMKLLGANEFLPQNAVLRWLSKKACEINNFEEAICENSLFVLCGHDEKQFNRSLLPIILGHVPAGASTKTLVHYAQEIRNKGRFQQFDYGAEGNYKEYGTETPPEYPLHKVTLPIALLSSQNDWLAGDADVVNLYDQLSNPIEHYVVPLKEFNHIDFLWAKDAPKLVYAKLLQLLEEGVSNNYNMDIENAII

Similarity

Belongs to the AB hydrolase superfamily. Lipase family.

Feature

chain  Lipase

Uniprot

H9J5B8   A0A2H1VB04   A0A0S1MM91   A0A2A4K7B0   A0A2W1BV18   A0A0L7KSX2   + More
A0A0L7LBN2   A0A0N1IA21   A0A212FL02   A0A0N0P9P4   A0A182VB02   A0A0L7LD93   A0A182PGK0   A0A182TMH4   A0A182JYW0   A0A182NS05   A0A182YB52   A0A084VGT2   A0A182M714   A0A182INM5   A0A182HLG5   A0A182HBR9   A0A2M4DRZ0   A0A182L9V7   A0A182WSL5   W5JQ53   A0A1Q3G4Y3   A0A182FP77   Q16MC7   K7J2Y1   B0WDK6   A0A182RZA1   A0A182VZF7   A0A182G6M0   S4NTM9   A0A212EIJ7   Q7PXY2   A0A232EG55   A0A1L8DQ12   A0A1L8DPQ6   A0A0N0PE67   A0A2H1VNV1   A0A2A4K5U1   A0A026X0Q1   A0A1J1HYK0   A0A336LYU0   H9J853   A0A2J7QW21   A0A1B6HSA1   Q2F5V1   A0A310SHS6   A0A151X254   D2A3G9   A0A194QAJ7   A0A158NIA5   A0A1B6G3S2   A0A1S3CXK0   A0A2J7QW32   V5FYL0   A0A158P269   A0A151IQS0   A0A195AVW7   A0A1Y1KWN7   A0A067R2Y8   A0A195FK23   F4W6F9   E2B370   A0A1B0CJ10   A0A0N0BCB2   A0A067RCF7   A0A195CME3   A0A0L7R340   A0A195F6E3   A0A088A7F6   A0A2J7PY44   A0A154PPL4   A0A226E1Q5   A0A1D2N240   F4WGG4   A0A2A3ED34   A0A195E3Z0   F4W6F8   A0A067RHQ8   A0A0C9R100   A0A194PL00   A0A158P268   A0A195AVE3   A0A1B0CTU8   A0A151X224   A0A195FI51   A0A195EGW8   A0A0T6BEX7   E9I8R3   A0A194R2Y3   A0A1L8DPW0   A0A067R0F9  

Pubmed

19121390    23811219    28756777    26227816    26354079    22118469    + More
25244985    24438588    26483478    20966253    20920257    23761445    17510324    20075255    23622113    12364791    14747013    17210077    28648823    24508170    22649392    18362917    19820115    21347285    28004739    24845553    21719571    20798317    27289101    21282665   

EMBL

BABH01037038    KC702800    AGN90923.1    ODYU01001573    SOQ37981.1    KR821071    + More
ALL42058.1    NWSH01000071    PCG79959.1    KZ149927    PZC77505.1    JTDY01006004    KOB66378.1    JTDY01001814    KOB72805.1    KQ460426    KPJ14773.1    AGBW02008987    AGBW02007925    OWR51966.1    OWR54421.1    KQ459256    KPJ02070.1    JTDY01001689    KOB73151.1    ATLV01013084    KE524839    KFB37176.1    AXCM01002120    APCN01000897    JXUM01125660    JXUM01125661    JXUM01125662    KQ566971    KXJ69694.1    GGFL01016104    MBW80282.1    ADMH02000799    ETN65025.1    GFDL01000188    JAV34857.1    CH477866    EAT35492.1    DS231898    EDS44615.1    JXUM01045142    KQ561427    KXJ78623.1    GAIX01012151    JAA80409.1    AGBW02014621    OWR41323.1    AAAB01008987    EAA00922.5    NNAY01004862    OXU17327.1    GFDF01005649    JAV08435.1    GFDF01005648    JAV08436.1    KQ460044    KPJ18326.1    ODYU01003406    SOQ42132.1    NWSH01000095    PCG79625.1    KK107054    EZA61581.1    CVRI01000027    CRK92404.1    UFQT01000235    SSX22181.1    BABH01039868    KC702799    AB983536    AGN90922.1    BAQ20441.1    NEVH01009768    PNF32787.1    GECU01030185    JAS77521.1    DQ311322    ABD36266.1    KQ759878    OAD62255.1    KQ982580    KYQ54458.1    KQ971338    EFA02315.1    KQ459232    KPJ02558.1    ADTU01016204    ADTU01016205    GECZ01012738    JAS57031.1    PNF32784.1    GALX01005701    JAB62765.1    ADTU01007002    KQ976755    KYN08590.1    KQ976731    KYM76202.1    GEZM01073725    JAV64911.1    KK852794    KDR16427.1    KQ981523    KYN40354.1    GL887707    EGI70294.1    GL445305    EFN89852.1    AJWK01013948    KQ435918    KOX68734.1    KDR16428.1    KQ977622    KYN01254.1    KQ414664    KOC65191.1    KQ981763    KYN36038.1    NEVH01020850    PNF21255.1    KQ435012    KZC13809.1    LNIX01000009    OXA50396.1    LJIJ01000287    ODM99328.1    GL888128    EGI66931.1    KZ288296    PBC28931.1    KQ979657    KYN19900.1    EGI70293.1    KK852673    KDR18742.1    GBYB01006587    JAG76354.1    KQ459601    KPI94007.1    ADTU01007001    KYM76203.1    AJWK01028000    KYQ54457.1    KYN40355.1    KQ978957    KYN27132.1    LJIG01001091    KRT85849.1    GL761642    EFZ23043.1    KQ460855    KPJ11879.1    GFDF01005643    JAV08441.1    KK852827    KDR15388.1   

Proteomes

UP000005204    UP000218220    UP000037510    UP000053240    UP000007151    UP000053268    + More
UP000075903    UP000075885    UP000075902    UP000075881    UP000075884    UP000076408    UP000030765    UP000075883    UP000075880    UP000075840    UP000069940    UP000249989    UP000075882    UP000076407    UP000000673    UP000069272    UP000008820    UP000002358    UP000002320    UP000075900    UP000075920    UP000007062    UP000215335    UP000053097    UP000183832    UP000235965    UP000075809    UP000007266    UP000005205    UP000079169    UP000078542    UP000078540    UP000027135    UP000078541    UP000007755    UP000008237    UP000092461    UP000053105    UP000053825    UP000005203    UP000076502    UP000198287    UP000094527    UP000242457    UP000078492   

PRIDE

H9J5B8    H9J853    Q2F5V1   

Pfam

PF04083   Abhydro_lipase        + More
PF00561   Abhydrolase_1
PF01399   PCI
PF12146   Hydrolase_4
PF00100   Zona_pellucida

Interpro

IPR006693   AB_hydrolase_lipase        + More
IPR029058   AB_hydrolase       
IPR025483   Lipase_euk       
IPR000073   AB_hydrolase_1       
IPR000717   PCI_dom       
IPR036390   WH_DNA-bd_sf       
IPR022742   Hydrolase_4       
IPR011990   TPR-like_helical_dom_sf       
IPR019734   TPR_repeat       
IPR013026   TPR-contain_dom       
IPR001507   ZP_dom       

SUPFAM

SSF53474   SSF53474        + More
SSF46785   SSF46785       
SSF48452   SSF48452       

Gene 3D

3.40.50.1820     1.25.40.10    

ProteinModelPortal

H9J5B8   A0A2H1VB04   A0A0S1MM91   A0A2A4K7B0   A0A2W1BV18   A0A0L7KSX2   + More
A0A0L7LBN2   A0A0N1IA21   A0A212FL02   A0A0N0P9P4   A0A182VB02   A0A0L7LD93   A0A182PGK0   A0A182TMH4   A0A182JYW0   A0A182NS05   A0A182YB52   A0A084VGT2   A0A182M714   A0A182INM5   A0A182HLG5   A0A182HBR9   A0A2M4DRZ0   A0A182L9V7   A0A182WSL5   W5JQ53   A0A1Q3G4Y3   A0A182FP77   Q16MC7   K7J2Y1   B0WDK6   A0A182RZA1   A0A182VZF7   A0A182G6M0   S4NTM9   A0A212EIJ7   Q7PXY2   A0A232EG55   A0A1L8DQ12   A0A1L8DPQ6   A0A0N0PE67   A0A2H1VNV1   A0A2A4K5U1   A0A026X0Q1   A0A1J1HYK0   A0A336LYU0   H9J853   A0A2J7QW21   A0A1B6HSA1   Q2F5V1   A0A310SHS6   A0A151X254   D2A3G9   A0A194QAJ7   A0A158NIA5   A0A1B6G3S2   A0A1S3CXK0   A0A2J7QW32   V5FYL0   A0A158P269   A0A151IQS0   A0A195AVW7   A0A1Y1KWN7   A0A067R2Y8   A0A195FK23   F4W6F9   E2B370   A0A1B0CJ10   A0A0N0BCB2   A0A067RCF7   A0A195CME3   A0A0L7R340   A0A195F6E3   A0A088A7F6   A0A2J7PY44   A0A154PPL4   A0A226E1Q5   A0A1D2N240   F4WGG4   A0A2A3ED34   A0A195E3Z0   F4W6F8   A0A067RHQ8   A0A0C9R100   A0A194PL00   A0A158P268   A0A195AVE3   A0A1B0CTU8   A0A151X224   A0A195FI51   A0A195EGW8   A0A0T6BEX7   E9I8R3   A0A194R2Y3   A0A1L8DPW0   A0A067R0F9  

PDB

1K8Q     E-value=1.12923e-74,     Score=713

KEGG

101739402    K01052 lysosomal acid lipase/cholesteryl ester hydrolase [EC:3.1.1.13] | (RefSeq) lipase 3-like

PATHWAY

00100    Steroid biosynthesis - Bombyx mori (domestic silkworm)
04142    Lysosome - Bombyx mori (domestic silkworm)

GO

GO:0006629   GO:0016788   GO:0016042   GO:0005737   GO:0044255   GO:0016298   GO:0016021   GO:0008270   GO:0006511   GO:0007275   GO:0006397   GO:0048869   GO:0003676   GO:0016491   GO:0015930  

Subcellular location

Cytoplasm  

SignalP

Position:   1 - 20,         Likelihood:  0.990430

 

 

Length:

480

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

2.5343

Exp number, first 60 AAs:

2.42745

Total prob of N-in:

0.11931

outside

1  -  480

 

 

Pi

47.44297

Theta

48.782542

Tajima's D

-1.496443

CLR

0

CSRT

0.0609469526523674

Interpretation

Uncertain