Gene

KWMTBOMO13273

Pre Gene Modal

BGIBMGA004722

Annotation

PREDICTED:_probable_tubulin_polyglutamylase_TTLL2_[Plutella_xylostella]

Location

Bomo_Chr22(-):12597070-12600726      View in EpiBrowser

Full name

Metalloendopeptidase       + More
Probable tubulin polyglutamylase TTLL2      

Alternative Name

Testis-specific protein NYD-TSPG
Tubulin--tyrosine ligase-like protein 2

Location in the cell

Cytoplasmic   Reliability : 1.089 Mitochondrial   Reliability : 1.014

CDS

ATGGAGGGAACTTCTGAAGGTGATGAGCCATTTATTTATCGCCTGAATGATAATGGAACTGGACCGAACCTCGTAGTAAAGGTTTGCGCAGAACGTGGCTGGAGAATGTATCAAGGATATAACGGCAGTGAAGAGAAGTGGAATATTTGGTGGAGATCAAGCGCATTTCCCGCTGCCTGCTACAAAACCCTCGGAGATTGGCAGTTTATGAACCACATACCGAAGGGCGGTTCAATTTGTCGGAAAGATAATCTGTCTAGACTGCTTCGTTGTATGCGAAGAATATACGGAACCATTTATGATTTTACGTGA

Protein

MEGTSEGDEPFIYRLNDNGTGPNLVVKVCAERGWRMYQGYNGSEEKWNIWWRSSAFPAACYKTLGDWQFMNHIPKGGSICRKDNLSRLLRCMRRIYGTIYDFT

Description

Probable tubulin polyglutamylase that forms polyglutamate side chains on tubulin. Probably acts when complexed with other proteins (By similarity).

Cofactor

Zn(2+)

Similarity

Belongs to the tubulin--tyrosine ligase family.

Keywords

ATP-binding   Complete proteome   Ligase   Nucleotide-binding   Polymorphism   Reference proteome  

Feature

chain  Probable tubulin polyglutamylase TTLL2
sequence variant  In dbSNP:rs12526094.

Uniprot

A0A212EGW3   A0A2H1VC80   A0A2P8YIK8   A0A067RJS4   A0A1Y1N181   A0A2J7R2D0   + More
A0A088AHJ7   A0A1B6JXQ0   D6WN40   A0A1Y1MY90   A0A1Y1MZQ1   E0W3J3   A0A1Y1N4Y7   A0A1Y1N1U9   A0A232EMG7   K7IPN0   A0A158NG12   A0A154PSK5   E2B4Z4   A0A0N0BIN1   A0A146L3G4   A0A0A9ZEM7   A0A026WT51   A0A1S3DBE7   E9J5Z5   A0A2H1VDW8   A0A2S2NX14   J9LXJ1   A0A2A3EA39   A0A2S2QNK7   A0A2H8TJM1   A0A195F162   A0A194R0Q8   F4X6J0   A0A151I1A9   A0A151ILL8   A0A151XB30   A0A195E6Y1   T1I8T6   E2AHW8   U4UAS3   A0A146P2Y3   V3ZDV4   A0A3Q2ZX91   A0A2T7P571   A0A3S1B266   A0A1S3K320   A0A3R7PHN9   A0A1A7XFU7   R7UEE0   H0Y1Z8   W4YB41   T1JCA3   A0A3B4B5P6   A0A3P8Z276   A0A0F8CNJ1   A0A210QNA4   A0A3B5MW30   A0A3Q0QUE1   A0A3B4C3L0   A0A1Y2CJ35   G1NJJ1   A0A2G8KU34   A0A2P4SN25   M3ZTI2   A0A3P8V296   A0A3Q3GCE8   A0A087XB40   A0A1D2MQN9   G3T7V1   A0A3Q2UL39   H3ATC5   A0A3B3WEB6   D3ZF82   A0A3Q1JPK0   A0A1S3S8F9   A0A3B4XAA6   A0A3B4TG99   A0A3Q3ILJ9   W5NFG8   A0A226MQD8   A0A3Q3MYT7   A0A3B3T0J7   I3KFF5   A0A2I3G963   A0A3P8SYJ0   H2QU17   B4DX04   Q9BWV7   A0A2R9CL98   A0A226PAM8   A0A3B3IRU1   A0A2G8L9U5   A0A2K5PW39   A0A1U7SHL5   A0A2J8KHE9  

EC Number

3.4.24.-
6.-.-.-

Pubmed

22118469    29403074    24845553    28004739    18362917    19820115    + More
20566863    28648823    20075255    21347285    20798317    26823975    25401762    24508170    21282665    26354079    21719571    23537049    23254933    25463417    25069045    25835551    28812685    20838655    29023486    23542700    24487278    27289101    15592404    9215903    15057822    29240929    25186727    16136131    14702039    14574404    15489334    22722832    24621616   

EMBL

AGBW02015005    OWR40716.1    ODYU01001757    SOQ38396.1    PYGN01000569    PSN44091.1    + More
KK852588    KDR20781.1    GEZM01017511    JAV90640.1    NEVH01007841    PNF34976.1    GECU01003747    JAT03960.1    KQ971343    EFA04346.2    GEZM01017518    JAV90633.1    GEZM01017513    JAV90638.1    DS235882    EEB20199.1    GEZM01017514    JAV90637.1    GEZM01017516    JAV90635.1    NNAY01003363    OXU19546.1    ADTU01014881    KQ435119    KZC14737.1    GL445685    EFN89202.1    KQ435727    KOX77912.1    GDHC01015626    JAQ03003.1    GBHO01003334    JAG40270.1    KK107109    EZA59113.1    GL768221    EFZ11682.1    ODYU01002033    SOQ39033.1    GGMR01003589    GGMR01009055    MBY16208.1    MBY21674.1    ABLF02036898    KZ288310    PBC28588.1    GGMS01010143    MBY79346.1    GFXV01002538    MBW14343.1    KQ981864    KYN34203.1    KQ460883    KPJ11287.1    GL888818    EGI57950.1    KQ976580    KYM79886.1    KQ977104    KYN05781.1    KQ982335    KYQ57593.1    KQ979568    KYN20943.1    ACPB03000006    GL439602    EFN66958.1    KB631904    ERL87060.1    GCES01148054    JAQ38268.1    KB202619    ESO89298.1    PZQS01000006    PVD28575.1    RQTK01000966    RUS73200.1    QCYY01002881    ROT66844.1    HADW01015532    SBP16932.1    AMQN01008008    KB301969    ELU04904.1    AAQR03089993    AAGJ04128372    JH432064    KQ041710    KKF23730.1    NEDP02002733    OWF50223.1    MCGO01000015    ORY46917.1    MRZV01000368    PIK51523.1    PPHD01033918    POI25510.1    AYCK01020448    LJIJ01000715    ODM95085.1    AADN05000003    AFYH01085564    AABR07001576    AHAT01008273    MCFN01000547    OXB57472.1    AERX01042456    AERX01042457    ADFV01068427    ADFV01068428    AACZ04028930    AK301755    BAG63216.1    AY026506    AK093039    AK314450    AL021331    CH471051    BC030650    BC047411    AJFE02069241    AWGT02000118    OXB76570.1    MRZV01000158    PIK56985.1    NBAG03000370    PNI34442.1    PNI34443.1   

Proteomes

UP000007151    UP000245037    UP000027135    UP000235965    UP000005203    UP000007266    + More
UP000009046    UP000215335    UP000002358    UP000005205    UP000076502    UP000008237    UP000053105    UP000053097    UP000079169    UP000007819    UP000242457    UP000078541    UP000053240    UP000007755    UP000078540    UP000078542    UP000075809    UP000078492    UP000015103    UP000000311    UP000030742    UP000265000    UP000030746    UP000264800    UP000245119    UP000271974    UP000085678    UP000283509    UP000014760    UP000005225    UP000007110    UP000261520    UP000265140    UP000242188    UP000261380    UP000261340    UP000261440    UP000193642    UP000001645    UP000230750    UP000002852    UP000265120    UP000261660    UP000028760    UP000094527    UP000007646    UP000000539    UP000008672    UP000261480    UP000002494    UP000265040    UP000087266    UP000261360    UP000261420    UP000261600    UP000018468    UP000198323    UP000261640    UP000261540    UP000005207    UP000001073    UP000265080    UP000002277    UP000005640    UP000240080    UP000198419    UP000233040    UP000189705   

PRIDE

D3ZF82    B4DX04    Q9BWV7   

Pfam

PF03133   TTL        + More
PF00620   RhoGAP
PF01400   Astacin

Interpro

IPR013815   ATP_grasp_subdomain_1        + More
IPR004344   TTL/TTLL_fam       
IPR000198   RhoGAP_dom       
IPR008936   Rho_GTPase_activation_prot       
IPR024079   MetalloPept_cat_dom_sf       
IPR001506   Peptidase_M12A       

SUPFAM

SSF48350   SSF48350       

Gene 3D

3.30.1490.20     1.10.555.10     3.40.390.10    

ProteinModelPortal

A0A212EGW3   A0A2H1VC80   A0A2P8YIK8   A0A067RJS4   A0A1Y1N181   A0A2J7R2D0   + More
A0A088AHJ7   A0A1B6JXQ0   D6WN40   A0A1Y1MY90   A0A1Y1MZQ1   E0W3J3   A0A1Y1N4Y7   A0A1Y1N1U9   A0A232EMG7   K7IPN0   A0A158NG12   A0A154PSK5   E2B4Z4   A0A0N0BIN1   A0A146L3G4   A0A0A9ZEM7   A0A026WT51   A0A1S3DBE7   E9J5Z5   A0A2H1VDW8   A0A2S2NX14   J9LXJ1   A0A2A3EA39   A0A2S2QNK7   A0A2H8TJM1   A0A195F162   A0A194R0Q8   F4X6J0   A0A151I1A9   A0A151ILL8   A0A151XB30   A0A195E6Y1   T1I8T6   E2AHW8   U4UAS3   A0A146P2Y3   V3ZDV4   A0A3Q2ZX91   A0A2T7P571   A0A3S1B266   A0A1S3K320   A0A3R7PHN9   A0A1A7XFU7   R7UEE0   H0Y1Z8   W4YB41   T1JCA3   A0A3B4B5P6   A0A3P8Z276   A0A0F8CNJ1   A0A210QNA4   A0A3B5MW30   A0A3Q0QUE1   A0A3B4C3L0   A0A1Y2CJ35   G1NJJ1   A0A2G8KU34   A0A2P4SN25   M3ZTI2   A0A3P8V296   A0A3Q3GCE8   A0A087XB40   A0A1D2MQN9   G3T7V1   A0A3Q2UL39   H3ATC5   A0A3B3WEB6   D3ZF82   A0A3Q1JPK0   A0A1S3S8F9   A0A3B4XAA6   A0A3B4TG99   A0A3Q3ILJ9   W5NFG8   A0A226MQD8   A0A3Q3MYT7   A0A3B3T0J7   I3KFF5   A0A2I3G963   A0A3P8SYJ0   H2QU17   B4DX04   Q9BWV7   A0A2R9CL98   A0A226PAM8   A0A3B3IRU1   A0A2G8L9U5   A0A2K5PW39   A0A1U7SHL5   A0A2J8KHE9  

PDB

4YLS     E-value=0.00636627,     Score=86

KEGG

101742158    K16600 tubulin polyglutamylase TTLL2 [EC:6.-.-.-] | (RefSeq) probable tubulin polyglutamylase TTLL2

GO

GO:0006464   GO:0005524   GO:0016021   GO:0007165   GO:0016874   GO:0004222   GO:0046872  

Length:

103

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.00753

Exp number, first 60 AAs:

0.00579

Total prob of N-in:

0.09611

outside

1  -  103

 

 

Pi

282.428447

Theta

203.450805

Tajima's D

1.267549

CLR

0.138802

CSRT

0.730213489325534

Interpretation

Uncertain