Gene

KWMTBOMO13249  Validated by peptides from experiments

Pre Gene Modal

BGIBMGA004726

Annotation

PREDICTED:_antichymotrypsin-2-like_[Bombyx_mori]

Location

Bomo_Chr22(+):11615440-11632396      View in EpiBrowser

Full name

Antichymotrypsin-2      

Alternative Name

Antichymotrypsin II

Location in the cell

Extracellular   Reliability : 2.41

CDS

ATGCCTTATAACTCATGCAATGGGGATCCGAACGCTGTTGCTGGATGTGGAGTAAATTGTAACAGACATTGTTCTGATATCGGCAAAGAATGTCAAAGTTGTGCTGCTGTTTGCTACGAAGACGGCTGCGATTGTAAAGACGGATATTATTACGATGATAACATTAATAAATGTGTTTTACCCGAAGACTGCACTCCTACTTGTGGTAATGATGAAGTCTACAATGATTGTATACAAGGGTACTGCCAACCGAAGAATTGTTCGGAAATAGGGAAACCCGTTGCTTGCCCAAGAATAGATCCCAAGAATTGCATCAAAGGGTGCTTGTGTAAAGAAGACTACGTCAGAGCTGATAATGGAACGTGTATACCAAAAATCGACTGTCCTACTACCAATTCATCGGGAAATGTTGACCAATCCTTGGAAAAACTCCGCAGAGGAAACATGGCATTAGTTGGCCAGTTTCTTTGGGAATTATACAAAATGAATCCAGGACAAAGTTTCGTTACATCACCCGTATCTGTACTCATTCCTTACGGTCAACTAGCGCTATACGCCGTTAGAGAAACTTTAGATCAACTATTAAAGTTTATAAACCTCGACAATAAGGATCAGATCAAGGAAGCTTTCCCCGCTTTGCTTACGAATTATCGGTCTCAAAGCTCAGTTCTTTTGACGGTGGCAGTTAAATGCTACGGCAACATAAATTATCCTTTTACGGACCAGTTTAAGAACGACGCTGTAACTTACTTTGACTCAGAAGGAGAAAATATTGATTTTAAATATGCGAAAGAAGCTGCAGACACAATAAACGGATGGGTCGCAAACAAAACTAATAACTTAATTCAAAATCTTGTCAGCGAAGATTTGTTCAGCGATGACACTAGATTGGTTCTAGTTAACGGCATTTATTTCCTGGGAAATTGGCAAAATCAGTTCAATCCTAATAACACTCGCGATAGAGACTTCTACATCACACCAAACAAAACTAAGTCCATAAAGACTATGTATCAAGAAAACAACTTTAATTATGGAGAAAACGAGATTCTCGATGCACAGATCTTAGAATTGTTCTACAAAGGCGGCAATTCTAGTTTAGTAATCTTGTTACCAAAGAAAAAAGATGGCCTTCTCCAGATGTTAGATAAATTACGAAATTCAGATGAATTATCTAATAGCATTAAATCACTTAGGCAAGAGAAAGTCAAATGTTTCCTACCTAAGATGGATATAGAAACGAACATCGATATAGCAGAACTTTCCCAGAAGCTGAATGTAACCAAAATGTTCGATCCACGATCAGATGATTTCGAAGGAATTTTATTAAATTCGGACCCTGTATATGTTTCTGCTGCAATACAGAAAGCTAAAATCATAGTTGATGAAACTGGAACCGAGGCAGCGGCAGCAACTGTTATACTTCTGTACTCATTTAGAAATGCATTTGATCCTTTATTTGTTCAACAAGATATTTTGGATTCAGATTTACAAGACCATCCACACGTATTCTTCGTTTTGATTAACGATGAACCAATTTTCAGTGGATTGTTCATAGGTGCCTAA

Protein

MPYNSCNGDPNAVAGCGVNCNRHCSDIGKECQSCAAVCYEDGCDCKDGYYYDDNINKCVLPEDCTPTCGNDEVYNDCIQGYCQPKNCSEIGKPVACPRIDPKNCIKGCLCKEDYVRADNGTCIPKIDCPTTNSSGNVDQSLEKLRRGNMALVGQFLWELYKMNPGQSFVTSPVSVLIPYGQLALYAVRETLDQLLKFINLDNKDQIKEAFPALLTNYRSQSSVLLTVAVKCYGNINYPFTDQFKNDAVTYFDSEGENIDFKYAKEAADTINGWVANKTNNLIQNLVSEDLFSDDTRLVLVNGIYFLGNWQNQFNPNNTRDRDFYITPNKTKSIKTMYQENNFNYGENEILDAQILELFYKGGNSSLVILLPKKKDGLLQMLDKLRNSDELSNSIKSLRQEKVKCFLPKMDIETNIDIAELSQKLNVTKMFDPRSDDFEGILLNSDPVYVSAAIQKAKIIVDETGTEAAAATVILLYSFRNAFDPLFVQQDILDSDLQDHPHVFFVLINDEPIFSGLFIGA

Miscellaneous

The N-terminal section (1-336) is identical to the N-terminal section of the silk moth antitrypsin I (17-352).

Similarity

Belongs to the serpin family.

Keywords

Complete proteome   Direct protein sequencing   Protease inhibitor   Reference proteome   Secreted   Serine protease inhibitor  

Feature

chain  Antichymotrypsin-2

Uniprot

A0A3G1T1Q1   A0A2A4J7B9   G9F9J2   H9J5D8   A0A3S2M6W8   G9F9J3   + More
A0A3G1T1R3   A0A194R0R3   A0A1E1WCC9   A0A194PXE0   A0A1E1WM18   A0A1E1W9X2   A0A212EGT4   A0A3S2NJW5   K4P392   Q25492   A3KEZ7   Q25501   Q60FS0   Q25495   Q25500   B4XH99   F5B4G8   Q25498   I4DJC8   J7HI16   A0A194PZ13   C7ASM4   A0A2H1VE36   C7ASM3   C7ASM6   A0A3G1T1E7   P80034   C7ASM7   B0FZ61   C5I794   A0A0M4K7J2   Q8IS86   B0FZ64   B0FZ60   B0FZ62   B0FZ63   A0A212FD15   A0A2A4JQC6   A0A2A4JPB5   Q8MPN5   Q8MPN7  

Pubmed

19121390    26354079    22118469    8910411    19524698    22651552    + More
21104446    1761030    19481148    10731132    12137947    12537568    12537572    12537573    12537574    16110336    17569856    17569867    26109357    26109356   

EMBL

MG770320    AXY94922.1    NWSH01002542    PCG68017.1    JN033737    AEW46890.2    + More
BABH01039203    BABH01039204    BABH01039205    BABH01039206    BABH01039207    RSAL01000018    RVE52848.1    JN033738    AEW46891.2    MG770321    AXY94923.1    KQ460883    KPJ11292.1    GDQN01006457    JAT84597.1    KQ459586    KPI97992.1    GDQN01003022    JAT88032.1    GDQN01007288    JAT83766.1    AGBW02015025    OWR40695.1    RVE52846.1    JX524148    AFV46312.1    U58361    AAC47338.1    AB295498    BAF48334.1    AAC47339.1    AB189029    BAD52261.1    AAC47341.1    AAC47335.1    EU040208    ABW17156.1    HQ615869    ADT63775.1    AAC47342.1    AK401396    BAM18018.1    JN400442    AFQ01141.1    KPI97989.1    FJ613795    ACT36274.1    ODYU01002062    SOQ39103.1    FJ613794    FJ613796    ACT36273.1    ACT36275.1    FJ613797    ACT36278.1    MG992370    AXY94808.1    ACT36277.1    ACT36279.1    EU368832    ABY68562.1    FJ763763    ACR56864.1    KR003729    ALD62507.1    AY148483    AAN71632.1    ABY68559.1    ABY68563.1    ABY68561.1    ABY68560.1    AGBW02009121    OWR51607.1    NWSH01000840    PCG73908.1    PCG73905.1    AE013599    AJ428889    AAS64783.1    CAD21901.1    BT125838    AJ428884    AAS64782.1    ADR83723.1    CAD21896.1   

Proteomes

UP000218220    UP000005204    UP000283053    UP000053240    UP000053268    UP000007151    + More
UP000000803   

PRIDE

H9J5D8    C7ASM4    C7ASM3    C7ASM6    P80034    C7ASM7    + More
Q8MPN7   

Pfam

PF01826   TIL        + More
PF00079   Serpin

Interpro

IPR036186   Serpin_sf        + More
IPR000215   Serpin_fam       
IPR042178   Serpin_sf_1       
IPR023795   Serpin_CS       
IPR002919   TIL_dom       
IPR042185   Serpin_sf_2       
IPR036084   Ser_inhib-like_sf       
IPR023796   Serpin_dom       
IPR000742   EGF-like_dom       

SUPFAM

SSF57567   SSF57567        + More
SSF56574   SSF56574       

Gene 3D

2.30.39.10     3.30.497.10    

ProteinModelPortal

A0A3G1T1Q1   A0A2A4J7B9   G9F9J2   H9J5D8   A0A3S2M6W8   G9F9J3   + More
A0A3G1T1R3   A0A194R0R3   A0A1E1WCC9   A0A194PXE0   A0A1E1WM18   A0A1E1W9X2   A0A212EGT4   A0A3S2NJW5   K4P392   Q25492   A3KEZ7   Q25501   Q60FS0   Q25495   Q25500   B4XH99   F5B4G8   Q25498   I4DJC8   J7HI16   A0A194PZ13   C7ASM4   A0A2H1VE36   C7ASM3   C7ASM6   A0A3G1T1E7   P80034   C7ASM7   B0FZ61   C5I794   A0A0M4K7J2   Q8IS86   B0FZ64   B0FZ60   B0FZ62   B0FZ63   A0A212FD15   A0A2A4JQC6   A0A2A4JPB5   Q8MPN5   Q8MPN7  

PDB

1SEK     E-value=5.68576e-59,     Score=578

KEGG

101737176    no KO assigned | (RefSeq) antichymotrypsin-2-like

GO

GO:0005615   GO:0008233   GO:0004867   GO:0010955   GO:0060570   GO:0004869   GO:0010951  

PANTHER

PTHR11461  

Subcellular location

Secreted  

Length:

520

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.10772

Exp number, first 60 AAs:

0

Total prob of N-in:

0.00514

outside

1  -  520

 

 

Pi

153.293792

Theta

19.733854

Tajima's D

0

CLR

1.561678

CSRT

0.368831558422079

Interpretation

Uncertain