Gene

KWMTBOMO13201

Pre Gene Modal

BGIBMGA009956

Annotation

U2_small_nuclear_ribonucleoprotein_A'_[Bombyx_mori]

Location

Bomo_Chr22(+):10075437-10079107      View in EpiBrowser

Full name

Eukaryotic translation initiation factor 3 subunit G      

Alternative Name

Eukaryotic translation initiation factor 3 RNA-binding subunit
Eukaryotic translation initiation factor 3 subunit 4

Location in the cell

Nuclear   Reliability : 4.321

CDS

ATGGTCAAACTTACAACGGAGCTCATACAAAACTCTATGCAATATATGAATCCTTGTAGGGACCGAGAACTGGATCTTAGAGGTTATAAGATTCCACAAATCGAAAATCTGGGTGCTACGCTCGATCAATTTGATACGATAGACTTCTCGGACAACGACATCAGAAAGCTTGACGGTTTTCCACTGCTAAAAAGGTTGAAATGTATTCTATTGAATAATAACAGGATCGTGAGGATAGGAGAGAATTTGGAACATTATATACCAAATTTAGAGTCTGTGATTTTAACAAACAACAATATCTCAGAACTTGGTGATTTGGATCCATTAAGTACATTACCAAAGCTGCGAACATTATCACTCATGCACAATCCAGTTGCCAACAAAAACCATTATAGGGCATATGTGGCATTCAAAATGCCAGAGCTAAGATTATTGGACTTCAGGAAGATTAAACAAAAAGAGAGAGATGAAGCTAATACATTGTTCAAGAGTAGAAAAGGGAAAGAAATACAGAGGGAGATTGCTAAAAAAGCAAAGACATTTGTACCTGGTGGAAATATGCCTGATCCTAAAGTTACAAATCTTACACCTCAAGAAATCCATAAGATCCGAGAAGCAATCAAGAATGCATCATCCCTACAGGAGGTCGAACGTCTGACAAGAATGTTGCAGTCTGGTCAGATTCCAGGGCAAAAACCTTTACAGCCCGTGACACAAACAAATGGTCAACAAGATGAAGATGAGGAAATGGACACGGATCAAGCAAACGGACAGTAG

Protein

MVKLTTELIQNSMQYMNPCRDRELDLRGYKIPQIENLGATLDQFDTIDFSDNDIRKLDGFPLLKRLKCILLNNNRIVRIGENLEHYIPNLESVILTNNNISELGDLDPLSTLPKLRTLSLMHNPVANKNHYRAYVAFKMPELRLLDFRKIKQKERDEANTLFKSRKGKEIQREIAKKAKTFVPGGNMPDPKVTNLTPQEIHKIREAIKNASSLQEVERLTRMLQSGQIPGQKPLQPVTQTNGQQDEDEEMDTDQANGQ

Description

RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation. This subunit can bind 18S rRNA.

Subunit

Component of the eukaryotic translation initiation factor 3 (eIF-3) complex.

Similarity

Belongs to the eIF-3 subunit G family.
Belongs to the AB hydrolase superfamily. Lipase family.

Uniprot

Q1HPT8   A0A2H1VAT2   I4DQ07   A0A2A4J589   A0A194PYY0   A0A194R635   + More
A0A212F1I5   S4NXT5   A0A3S2NLT7   A0A1B6HQH5   D6X367   A0A1B6GB34   A0A0T6B763   A0A1W4WZ85   J3JYS5   N6U2A7   W5JMV1   A0A2M4AVU5   A0A2M4BXY6   A0A2M4BX33   A0A2M4BWX9   A0A2M3ZB29   A0A2M3ZAZ1   A0A2M3ZB90   A0A182U4S2   A0A084VF74   A0A182P9X7   A0A182JC20   A0A182X6I1   A7UR52   A0A182UXT6   Q7PTD2   A0A182I3T2   A0A1B0DID1   A0A182JQV2   A0A182FCR6   A0A1L8DGL9   Q16LG3   A0A1Y1MPQ6   Q16LG5   Q16LG4   Q16LG6   A0A182WIV5   A0A2R7WT93   A0A1B6CPM3   A0A182KRY0   Q174L8   A0A182XZF3   A0A023ENQ1   A0A182RB48   B0VZR9   A0A1S3D0V5   A0A1Q3F0U7   A0A1Q3F110   A0A1Q3F0Q8   A0A182MMD6   A0A182Q9F4   A0A182NHF6   A0A1B0CMS4   A0A067R7N0   A0A2J7QVT5   A0A1B6KTH9   A0A182SER0   A0A0V0GBQ2   A0A069DR77   A0A0P4VUP2   T1I4W8   A0A1J1J5Y1   A0A087SV85   A0A0M9A8J2   A0A151XA68   A0A146LRS6   A0A151I3U9   A0A158NN78   A0A310S635   A0A154PBH6   H9G762   F4WLM4   A0A195FY62   A0A195EE56   A0A195CRW6   A0A2A3ELD4   A0A088ARL2   H3BFR2   A0A2T7NRJ1   E2C5R4   A0A2D0RWB7   U5EHD7   A0A093GJG3   U3K6I7   A0A026VXI4   A0A1W7R5G0   A0A0E9WZ34   A0A218V0C2   H0ZF70   A0A091EA46   A0A3L8SLR3   A0A3Q1EK11   F1NAC8   A0A0J7KYP6  

Pubmed

22651552    26354079    22118469    23622113    18362917    19820115    + More
22516182    23537049    20920257    23761445    24438588    12364791    14747013    17210077    17510324    28004739    20966253    25244985    24945155    24845553    26334808    27129103    26823975    21347285    21881562    21719571    9215903    20798317    24508170    30249741    25613341    20360741    30282656    15592404   

EMBL

DQ443314    ABF51403.1    ODYU01001568    SOQ37960.1    AK403876    BAM19997.1    + More
NWSH01003294    PCG66600.1    KQ459586    KPI97954.1    KQ460883    KPJ11326.1    AGBW02010868    OWR47597.1    GAIX01012032    JAA80528.1    RSAL01000040    RVE50950.1    GECU01030792    JAS76914.1    KQ971372    EFA10336.2    GECZ01010124    JAS59645.1    LJIG01009386    KRT83184.1    BT128405    AEE63363.1    APGK01042531    KB741006    KB632342    ENN75675.1    ERL93012.1    ADMH02001104    ETN64099.1    GGFK01011560    MBW44881.1    GGFJ01008732    MBW57873.1    GGFJ01008421    MBW57562.1    GGFJ01008436    MBW57577.1    GGFM01005005    MBW25756.1    GGFM01004956    MBW25707.1    GGFM01005021    MBW25772.1    ATLV01012364    KE524785    KFB36618.1    AAAB01008807    EDO64515.1    EAA04073.4    APCN01000220    AJVK01015500    GFDF01008482    JAV05602.1    CH477907    EAT35153.1    GEZM01024956    JAV87674.1    EAT35154.1    EAT35155.1    EAT35156.1    KK855487    PTY22786.1    GEDC01021872    GEDC01018239    GEDC01005656    JAS15426.1    JAS19059.1    JAS31642.1    CH477408    EAT41539.1    GAPW01003033    JAC10565.1    DS231815    EDS35161.1    GFDL01013862    JAV21183.1    GFDL01013802    JAV21243.1    GFDL01013902    JAV21143.1    AXCM01000560    AXCN02000591    AJWK01019143    KK852652    KDR19400.1    NEVH01009772    PNF32682.1    GEBQ01025232    JAT14745.1    GECL01000505    JAP05619.1    GBGD01002529    JAC86360.1    GDKW01000168    JAI56427.1    ACPB03011499    CVRI01000070    CRL07402.1    KK112119    KFM56774.1    KQ435720    KOX78656.1    KQ982351    KYQ57244.1    GDHC01008105    JAQ10524.1    KQ976475    KYM83926.1    ADTU01021128    KQ768821    OAD53047.1    KQ434856    KZC08754.1    AAWZ02033959    GL888208    EGI64960.1    KQ981208    KYN44774.1    KQ979039    KYN23391.1    KQ977372    KYN03237.1    KZ288222    PBC32082.1    AFYH01023887    AFYH01023888    PZQS01000010    PVD23776.1    GL452796    EFN76721.1    GANO01003067    JAB56804.1    KL215846    KFV66924.1    AGTO01020922    KK107672    QOIP01000008    EZA48146.1    RLU19770.1    GEHC01001227    JAV46418.1    GBXM01012958    JAH95619.1    MUZQ01000079    OWK59409.1    ABQF01016589    KK717966    KFO53502.1    QUSF01000015    RLW03719.1    AADN05000047    LBMM01001999    KMQ95419.1   

Proteomes

UP000218220    UP000053268    UP000053240    UP000007151    UP000283053    UP000007266    + More
UP000192223    UP000019118    UP000030742    UP000000673    UP000075902    UP000030765    UP000075885    UP000075880    UP000076407    UP000007062    UP000075903    UP000075840    UP000092462    UP000075881    UP000069272    UP000008820    UP000075920    UP000075882    UP000076408    UP000075900    UP000002320    UP000079169    UP000075883    UP000075886    UP000075884    UP000092461    UP000027135    UP000235965    UP000075901    UP000015103    UP000183832    UP000054359    UP000053105    UP000075809    UP000078540    UP000005205    UP000076502    UP000001646    UP000007755    UP000078541    UP000078492    UP000078542    UP000242457    UP000005203    UP000008672    UP000245119    UP000008237    UP000221080    UP000053875    UP000016665    UP000053097    UP000279307    UP000197619    UP000007754    UP000052976    UP000276834    UP000257200    UP000000539    UP000036403   

PRIDE

Q1HPT8   

Pfam

PF00076   RRM_1        + More
PF12353   eIF3g
PF00151   Lipase

Interpro

IPR032675   LRR_dom_sf        + More
IPR001611   Leu-rich_rpt       
IPR035979   RBD_domain_sf       
IPR017334   eIF3_g       
IPR024675   eIF3g_N       
IPR034240   eIF3G_RRM       
IPR012677   Nucleotide-bd_a/b_plait_sf       
IPR000504   RRM_dom       
IPR003591   Leu-rich_rpt_typical-subtyp       
IPR033906   Lipase_N       
IPR002331   Lipase_panc       
IPR013818   Lipase/vitellogenin       
IPR029058   AB_hydrolase       
IPR000734   TAG_lipase       
IPR003603   U2A'_phosphoprotein32A_C       

SUPFAM

SSF54928   SSF54928        + More
SSF53474   SSF53474       

Gene 3D

3.80.10.10     3.30.70.330     3.40.50.1820    

CDD

cd12408  RRM_eIF3G_like
cd12933  eIF3G
cd00707  Pancreat_lipase_like

ProteinModelPortal

Q1HPT8   A0A2H1VAT2   I4DQ07   A0A2A4J589   A0A194PYY0   A0A194R635   + More
A0A212F1I5   S4NXT5   A0A3S2NLT7   A0A1B6HQH5   D6X367   A0A1B6GB34   A0A0T6B763   A0A1W4WZ85   J3JYS5   N6U2A7   W5JMV1   A0A2M4AVU5   A0A2M4BXY6   A0A2M4BX33   A0A2M4BWX9   A0A2M3ZB29   A0A2M3ZAZ1   A0A2M3ZB90   A0A182U4S2   A0A084VF74   A0A182P9X7   A0A182JC20   A0A182X6I1   A7UR52   A0A182UXT6   Q7PTD2   A0A182I3T2   A0A1B0DID1   A0A182JQV2   A0A182FCR6   A0A1L8DGL9   Q16LG3   A0A1Y1MPQ6   Q16LG5   Q16LG4   Q16LG6   A0A182WIV5   A0A2R7WT93   A0A1B6CPM3   A0A182KRY0   Q174L8   A0A182XZF3   A0A023ENQ1   A0A182RB48   B0VZR9   A0A1S3D0V5   A0A1Q3F0U7   A0A1Q3F110   A0A1Q3F0Q8   A0A182MMD6   A0A182Q9F4   A0A182NHF6   A0A1B0CMS4   A0A067R7N0   A0A2J7QVT5   A0A1B6KTH9   A0A182SER0   A0A0V0GBQ2   A0A069DR77   A0A0P4VUP2   T1I4W8   A0A1J1J5Y1   A0A087SV85   A0A0M9A8J2   A0A151XA68   A0A146LRS6   A0A151I3U9   A0A158NN78   A0A310S635   A0A154PBH6   H9G762   F4WLM4   A0A195FY62   A0A195EE56   A0A195CRW6   A0A2A3ELD4   A0A088ARL2   H3BFR2   A0A2T7NRJ1   E2C5R4   A0A2D0RWB7   U5EHD7   A0A093GJG3   U3K6I7   A0A026VXI4   A0A1W7R5G0   A0A0E9WZ34   A0A218V0C2   H0ZF70   A0A091EA46   A0A3L8SLR3   A0A3Q1EK11   F1NAC8   A0A0J7KYP6  

PDB

6QX9     E-value=3.12644e-75,     Score=714

KEGG

732985    K11092 U2 small nuclear ribonucleoprotein A' | (RefSeq) U2 small nuclear ribonucleoprotein A'

PATHWAY

03040    Spliceosome - Bombyx mori (domestic silkworm)

GO

GO:0030620   GO:0005686   GO:0000398   GO:0033290   GO:0016282   GO:0003743   GO:0005852   GO:0001732   GO:0006629   GO:0004806   GO:0005576   GO:0071005   GO:0007283   GO:0016607   GO:0071007   GO:0005515   GO:0005739   GO:0008137   GO:0003824   GO:0016829   GO:0005737   GO:0048869   GO:0003676   GO:0016491   GO:0015930  

PANTHER

PTHR11610  

Subcellular location

Cytoplasm  
Secreted  

Length:

258

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0

Exp number, first 60 AAs:

0

Total prob of N-in:

0.04380

outside

1  -  258

 

 

Pi

248.631447

Theta

179.180469

Tajima's D

1.330478

CLR

0.000279

CSRT

0.751562421878906

Interpretation

Uncertain