Gene

KWMTBOMO13197  Validated by peptides from experiments

Pre Gene Modal

BGIBMGA009955

Annotation

PREDICTED:_deoxyribose-phosphate_aldolase-like_isoform_X1_[Amyelois_transitella]

Location

Bomo_Chr22(+):10014387-10019464      View in EpiBrowser

Full name

Deoxyribose-phosphate aldolase      

Alternative Name

2-deoxy-D-ribose 5-phosphate aldolase
Phosphodeoxyriboaldolase

Location in the cell

PlasmaMembrane   Reliability : 1.801

CDS

ATGGTGCGAGCTATTTTTGAAACTATTGATGATATGCCCTTAGATAATACATTTATAAATAAAAGCAATGTAGATTCTCAAGTAAAATCAATATTATACAACAATGTTGTGTCTCCTAAGGATGAGAGGGCATGGCTTATGAAAGCAATCACTCTAATTGACTTGACAACACTTTCTGGTGATGACACATCATCAAATGTTAGAAGACTTTGTCGGAAGGCTGCATATCCAATTCCAATTGATATTATGAATCCTTCTGATAATCTTCACACTGCAGCTGTCTGTGTCTACCCTACAAAGGTGCCTGATGTATGTACTGCTCTGAAGGCTATGAAGTTGGAAAAAAACATACAAGTGGCTGCAGTGGCTACAGGATTTCCGTCTGGTTTGTATCCTCTCGCAACGAGATTAGAAGAGATTCGGATGACCGTAGGGTATGGTGCAACAGAAATTGATGTGGTTATCGATAGGAGTTTAGTTTTGACCGGAGAATGGGAGACACTGTTTAATGAAATACAACAAATGAAGAAAGCATGCGGATCTGCACATCTCAAAGTTATTCTTGGCGTTGGCGAATTGGGAACTTATTATAATGTGTACAAAGCTTCAATGATCGCCATGATGGCTGGAGCGGACTTCATTAAGACATCGACCGGCAAAGAAGCCGTAAACGCAACGCTACCCATTGGTCTTGTCATGTGTCGGGCTATTAGAAGATATTATCAGATGACCGGTCATAAGGTTGGACTTAAACCGGCAGGTGGAATAAAAACTGTTCAGGATACACTGAATTGGTTAGTTCTTTTGTACACAGAGCTGGGTCCTGACTGGCTCACACCTGCCCTATTCAGGATTGGAGCGTCCAGTCTTCTGGACGTGATTATAAATCATTTAAAATCCACAAATCAGATTAGCTGTAGCTGA

Protein

MVRAIFETIDDMPLDNTFINKSNVDSQVKSILYNNVVSPKDERAWLMKAITLIDLTTLSGDDTSSNVRRLCRKAAYPIPIDIMNPSDNLHTAAVCVYPTKVPDVCTALKAMKLEKNIQVAAVATGFPSGLYPLATRLEEIRMTVGYGATEIDVVIDRSLVLTGEWETLFNEIQQMKKACGSAHLKVILGVGELGTYYNVYKASMIAMMAGADFIKTSTGKEAVNATLPIGLVMCRAIRRYYQMTGHKVGLKPAGGIKTVQDTLNWLVLLYTELGPDWLTPALFRIGASSLLDVIINHLKSTNQISCS

Description

Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate. Participates in stress granule (SG) assembly. May allow ATP production from extracellular deoxyinosine in conditions of energy deprivation.

Catalytic Activity

2-deoxy-D-ribose 5-phosphate = acetaldehyde + D-glyceraldehyde 3-phosphate

Subunit

Interacts with YBX1.

Similarity

Belongs to the DeoC/FbaB aldolase family. DeoC type 2 subfamily.

Keywords

Complete proteome   Cytoplasm   Lyase   Nucleus   Reference proteome   Schiff base  

Feature

chain  Deoxyribose-phosphate aldolase

Uniprot

H9JKA4   A0A2H1VAU7   A0A2H1V8V4   A0A3S2LJY7   S4PMF7   A0A194PYX5   + More
A0A212F1L4   A0A1Q3FDU9   B0WRC7   A0A2P8XFX9   A0A182F0W7   W5JAU3   A0A2M4BUS5   T1DKA8   D7EJ08   A0A2M4AV24   A0A2M4AVK4   A0A2J7RJI0   A0A182NF31   Q17G09   A0A182G2I8   A0A182QLF1   G1LA40   M3YJ84   A0A3Q2HI48   G1T6C1   A0A0V0G982   A0A2Y9RUV1   A0A182YCH6   A0A2I2UHA8   A0A2I3SJ20   A0A3P8WFT0   I3LXP1   A0A2I2ZSG6   V9KVM3   A0A1S4F4A5   A0A099Z5N7   A0A182M158   A0A3B4XJT4   A0A2R8ZRB1   H2Q5J5   A0A3Q7R5E2   Q9Y315   A0A2I3T1B0   F1PPB6   A0A2K5C0A3   A0A2K5C097   A0A2K5C0C1   A0A2K6LDR6   A0A3P8WDP3   A0A2K6T142   A0A2D0T4E5   A0A2K6T1C1   A0A2R8ZUH6   H9F930   A0A3Q2IDE8   D2HA66   G3QQS5   A0A2R8ZRC3   A0A2I3SNI6   A0A2U3WEM0   A0A2K6T1C5   G7PJY8   A0A182R6K4   G3RZY7   A0A2K6ED78   A0A2K5U9U9   A0A2K5XZ81   A0A0D9R7I1   A0A2I3N060   A0A2K5MA98   A0A2K5J1C3   F6XLA4   A0A2Y9H3J4   A0A1U7S877   A0A3B4V3P9   A0A2K5C0E7   A0A2K6LDS3   A0A3Q7VAG0   W5KVU7   A0A2K5J179   A0A384DEQ6   A0A2K6ED76   A0A2K5U9U0   A0A2K5XZ94   A0A2I3LLF2   A0A2K5MA88   A0A2K5J0W7   A0A2K5U9S7   A0A096N672   I3K9K7   M1EKL9   A0A2K5XZ73   A0A2I3NHF5   A0A2Y9IU31   H0X8G9   A0A182WH53   A0A2U9BB25   A0A2K6T1F6   A0A2U3ZGX2  

EC Number

4.1.2.4

Pubmed

19121390    23622113    26354079    22118469    29403074    20920257    + More
23761445    18362917    19820115    17510324    26483478    20010809    19892987    21993624    25244985    17975172    16136131    24487278    22398555    24402279    22722832    10810093    15489334    21269460    25229427    24275569    16341006    25319552    22002653    17431167    25329095    25186727    23236062   

EMBL

BABH01036839    ODYU01001568    SOQ37965.1    ODYU01001280    SOQ37280.1    RSAL01000086    + More
RVE48313.1    GAIX01003575    JAA88985.1    KQ459586    KPI97949.1    AGBW02010868    OWR47603.1    GFDL01009377    JAV25668.1    DS232054    EDS33317.1    PYGN01002284    PSN30911.1    ADMH02001915    ETN60523.1    GGFJ01007668    MBW56809.1    GAMD01001036    JAB00555.1    DS497692    EFA12496.1    GGFK01011316    MBW44637.1    GGFK01011483    MBW44804.1    NEVH01002992    PNF40983.1    CH477267    EAT45461.1    JXUM01039798    KQ561218    KXJ79315.1    AXCN02000830    ACTA01009862    ACTA01017862    ACTA01025862    AEYP01039891    AEYP01039892    AEYP01039893    AEYP01039894    AAGW02044803    AAGW02044804    AAGW02044805    GECL01001608    JAP04516.1    AANG04001751    AACZ04031281    AGTP01068389    AGTP01068390    AGTP01068391    AGTP01068392    CABD030083016    CABD030083017    CABD030083018    CABD030083019    CABD030083020    CABD030083021    JW870172    AFP02690.1    KL889661    KGL77016.1    AXCM01002218    AJFE02056092    AJFE02056093    AJFE02056094    GABC01009645    GABF01005996    GABD01005783    GABE01004242    NBAG03000025    JAA01693.1    JAA16149.1    JAA27317.1    JAA40497.1    PNI98334.1    AF132960    AK222541    BC056234    AAEX03015236    JU327383    AFE71139.1    GL192621    EFB27991.1    CM001286    EHH66123.1    AQIA01010186    AQIA01010187    AQIA01010188    AQIB01128531    AHZZ02001714    AHZZ02001715    JSUE03006235    JSUE03006236    JSUE03006237    JSUE03006238    JU471140    JV044385    CM001263    AFH27944.1    AFI34456.1    EHH20554.1    AERX01038186    JP008557    AER97154.1    AAQR03139537    AAQR03139538    AAQR03139539    CP026246    AWP00952.1   

Proteomes

UP000005204    UP000283053    UP000053268    UP000007151    UP000002320    UP000245037    + More
UP000069272    UP000000673    UP000007266    UP000235965    UP000075884    UP000008820    UP000069940    UP000249989    UP000075886    UP000008912    UP000000715    UP000002281    UP000001811    UP000248480    UP000076408    UP000011712    UP000002277    UP000265120    UP000005215    UP000001519    UP000053641    UP000075883    UP000261360    UP000240080    UP000286641    UP000005640    UP000002254    UP000233020    UP000233180    UP000233220    UP000221080    UP000245340    UP000009130    UP000075900    UP000233120    UP000233100    UP000233140    UP000029965    UP000028761    UP000233060    UP000233080    UP000006718    UP000248481    UP000189705    UP000261420    UP000286642    UP000018467    UP000261680    UP000005207    UP000248482    UP000005225    UP000075920    UP000246464   

PRIDE

H9JKA4    Q9Y315   

Pfam

PF01791   DeoC

Interpro

IPR002915   DeoC/FbaB/lacD_aldolase        + More
IPR011343   DeoC       
IPR013785   Aldolase_TIM       

Gene 3D

3.20.20.70    

CDD

cd00959  DeoC

ProteinModelPortal

H9JKA4   A0A2H1VAU7   A0A2H1V8V4   A0A3S2LJY7   S4PMF7   A0A194PYX5   + More
A0A212F1L4   A0A1Q3FDU9   B0WRC7   A0A2P8XFX9   A0A182F0W7   W5JAU3   A0A2M4BUS5   T1DKA8   D7EJ08   A0A2M4AV24   A0A2M4AVK4   A0A2J7RJI0   A0A182NF31   Q17G09   A0A182G2I8   A0A182QLF1   G1LA40   M3YJ84   A0A3Q2HI48   G1T6C1   A0A0V0G982   A0A2Y9RUV1   A0A182YCH6   A0A2I2UHA8   A0A2I3SJ20   A0A3P8WFT0   I3LXP1   A0A2I2ZSG6   V9KVM3   A0A1S4F4A5   A0A099Z5N7   A0A182M158   A0A3B4XJT4   A0A2R8ZRB1   H2Q5J5   A0A3Q7R5E2   Q9Y315   A0A2I3T1B0   F1PPB6   A0A2K5C0A3   A0A2K5C097   A0A2K5C0C1   A0A2K6LDR6   A0A3P8WDP3   A0A2K6T142   A0A2D0T4E5   A0A2K6T1C1   A0A2R8ZUH6   H9F930   A0A3Q2IDE8   D2HA66   G3QQS5   A0A2R8ZRC3   A0A2I3SNI6   A0A2U3WEM0   A0A2K6T1C5   G7PJY8   A0A182R6K4   G3RZY7   A0A2K6ED78   A0A2K5U9U9   A0A2K5XZ81   A0A0D9R7I1   A0A2I3N060   A0A2K5MA98   A0A2K5J1C3   F6XLA4   A0A2Y9H3J4   A0A1U7S877   A0A3B4V3P9   A0A2K5C0E7   A0A2K6LDS3   A0A3Q7VAG0   W5KVU7   A0A2K5J179   A0A384DEQ6   A0A2K6ED76   A0A2K5U9U0   A0A2K5XZ94   A0A2I3LLF2   A0A2K5MA88   A0A2K5J0W7   A0A2K5U9S7   A0A096N672   I3K9K7   M1EKL9   A0A2K5XZ73   A0A2I3NHF5   A0A2Y9IU31   H0X8G9   A0A182WH53   A0A2U9BB25   A0A2K6T1F6   A0A2U3ZGX2  

PDB

5C6M     E-value=1.2485e-36,     Score=383

KEGG

101741523    K01619 deoxyribose-phosphate aldolase [EC:4.1.2.4] | (RefSeq) deoxyribose-phosphate aldolase

PATHWAY

00030    Pentose phosphate pathway - Bombyx mori (domestic silkworm)
01100    Metabolic pathways - Bombyx mori (domestic silkworm)

GO

GO:0009264   GO:0004139   GO:0005737   GO:0016052   GO:0005634   GO:0046121   GO:0006098   GO:0046386   GO:0034774   GO:0005576   GO:0043312   GO:1904813   GO:0005829   GO:0003824   GO:0016829   GO:0048869   GO:0003676   GO:0016491   GO:0015930  

PANTHER

PTHR10889  

Subcellular location

Cytoplasm   Recruited to stress granules but not to processing bodies upon arsenite or clotrimazole treatment or energy deprivation.   With evidence from 2 publications.
Cytoplasmic granule   Recruited to stress granules but not to processing bodies upon arsenite or clotrimazole treatment or energy deprivation.   With evidence from 2 publications.
Nucleus   Recruited to stress granules but not to processing bodies upon arsenite or clotrimazole treatment or energy deprivation.   With evidence from 2 publications.

Length:

307

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.72198

Exp number, first 60 AAs:

0.00035

Total prob of N-in:

0.04715

outside

1  -  307

 

 

Pi

319.696009

Theta

230.889609

Tajima's D

1.583577

CLR

0

CSRT

0.806109694515274

Interpretation

Uncertain