Gene

KWMTBOMO13171  Validated by peptides from experiments

Pre Gene Modal

BGIBMGA000367

Annotation

eukaryotic_translation_initiation_factor_3_subunit_4_[Bombyx_mori]

Location

Bomo_Chr22(-):9492740-9497922      View in EpiBrowser

Full name

Eukaryotic translation initiation factor 3 subunit G       + More
Eukaryotic translation initiation factor 3 subunit G-1      

Alternative Name

Eukaryotic translation initiation factor 3 RNA-binding subunit
Eukaryotic translation initiation factor 3 subunit 4
Eukaryotic translation initiation factor 3 RNA-binding subunit 1
Eukaryotic translation initiation factor 3 subunit 4-1
Eukaryotic translation initiation factor 3 RNA-binding subunit-1

Location in the cell

Cytoplasmic   Reliability : 2.298 Nuclear   Reliability : 1.731

CDS

ATGCCTGTTGCTGAAGAATTTCAGGCTTCCTGGGCTGATGAGGTCGAGATTGACCAAGGTGTACTTCCACCACCTTCTGAAGTGGTTGAAAATGGACTAAAAATTGTTACGGAATATAAATACGACAATGATAACAAGAAAGTGAAAATTGTCAGGACATACAAAATTGAAAAACGTGTTGTTTCAAAGAGTATTGCCAAACGTAAAACTTGGAGCAAATTTGGAGATTCAGCCAGCGACAAGCCTGGGCCTAACCCTGCTACTACTAATGTAGCTGAAGATGTCTTCATGCAGTTCATCACCAGTAAGGAAGAGAGTCAACGCCCAGATGACGGGGAGCTTGATGGTCTTAAGCCACCATCCAGCAATGTTATCTTTAAGTGTCGTACATGTCAAGGAGACCATTTGACATTGTATTGTCCATTCAAGCACACTCAAATTGCACAAGCTAAAGCTGCTGAAGCTGCCAAAGCTGCAGAGGCAAAAGTTGCTGCTAGCAACAAGTACATTCCGCCCTCGTCTGCGGGACGTATACCTGGTCGTGATCAGCCCCCTGTGCGTCGTGAAGACGTAACTGCCATCCGTATATCAAACCTTAGCAATTTTGCAGTTGAAGCTGATATTGATGACCTTGTCAAAGGTTTTGGCCCTGTGCATAAACTGTACCTTGCGAAGGAAAAAAGTACTGGACATTGCAAAGGATTTGCTTATGTGCACTTCAAGTTCAGGGCAGATGCTGCGAAAGCAATTCAATCACTTAATGGTCATGGTTATGATCATCTGATTTTGAACGTGGAATGGTCTAAGCCTCCACAAAACAATTAA

Protein

MPVAEEFQASWADEVEIDQGVLPPPSEVVENGLKIVTEYKYDNDNKKVKIVRTYKIEKRVVSKSIAKRKTWSKFGDSASDKPGPNPATTNVAEDVFMQFITSKEESQRPDDGELDGLKPPSSNVIFKCRTCQGDHLTLYCPFKHTQIAQAKAAEAAKAAEAKVAASNKYIPPSSAGRIPGRDQPPVRREDVTAIRISNLSNFAVEADIDDLVKGFGPVHKLYLAKEKSTGHCKGFAYVHFKFRADAAKAIQSLNGHGYDHLILNVEWSKPPQNN

Description

RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation. This subunit can bind 18S rRNA.

Subunit

Component of the eukaryotic translation initiation factor 3 (eIF-3) complex.
Component of the eukaryotic translation initiation factor 3 (eIF-3) complex. The eIF-3 complex interacts with pix.

Similarity

Belongs to the eIF-3 subunit G family.

Keywords

Complete proteome   Cytoplasm   Initiation factor   Protein biosynthesis   Reference proteome   RNA-binding   Phosphoprotein  

Feature

chain  Eukaryotic translation initiation factor 3 subunit G

Uniprot

I1E4Y7   Q1HE00   A0A0L7L659   A0A1E1W806   A0A194R272   I4DK00   + More
S4NNR3   A0A212EVB0   A0A2H1V301   A0A2H1V345   A0A1Y1MLK1   D6X2C9   A0A0T6AZL2   A0A1W4XT48   A0A023EM15   A0A023EPC6   A0A0C9RXY2   A0A0N0BGU7   Q1HQN4   J3JYL7   A0A088AKE0   A0A2A3EMN6   V9IFS5   A0A067R0P4   A0A1B6FW19   A0A1B6FNI9   A0A1B6I6P7   A0A1B6J1U9   E2AFT4   A0A0J7L2I9   A0A151I0E9   B0VZS1   A0A158NSV4   F4WSJ3   A0A1Q3F3J5   A0A154P602   T1D4I0   A0A0L7QZZ0   A0A195B766   A0A195FNG2   F4WSS8   A0A151XD87   A0A1B0D7I8   A0A026X073   A0A158NH11   A0A3L8DV23   A0A195D168   A0A2J7QVY4   A0A1L8DS20   A0A1L8DSK7   A0A151J1Y4   A0A182WIV3   A0A195DPJ2   A0A195CTE5   A0A182VJ14   A0A182X6H9   A0A182KRX7   A0A182I3T1   Q7QJV0   A0A182UCM9   A0A336LXM6   A0A182NHF8   A0A182SXF5   A0A084VF76   A0A310S9W8   A0A182XZF5   A0A182MUR1   A0A182P9X5   A0A023F956   A0A182Q3J3   A0A0A9ZB41   A0A2M4BWB6   A0A0P4VNA1   R4G8D9   A0A0A9ZE63   A0A182JQV0   A0A2M3ZFU2   A0A0V0G5N9   A0A232EYC6   W5JI77   A0A069DRY2   A0A182RB50   A0A182J9H1   A0A195EYD7   A0A224XHA2   E9IPX0   B4NTY9   B4I9X1   K7IM65   Q9W4X7   A0A0K8VAW6   T1DRG8   B4MA85   U5EKM3   B4N1L0   B4L710   B4Q0Y7   B3P935   A0A1W4V9Y2   B3MYX2  

Pubmed

19121390    26227816    26354079    22651552    23622113    22118469    + More
28004739    18362917    19820115    24945155    26483478    17204158    17510324    22516182    23537049    24845553    20798317    21347285    21719571    24330624    24508170    30249741    20966253    12364791    24438588    25244985    25474469    25401762    26823975    27129103    28648823    20920257    23761445    26334808    21282665    17994087    20075255    10731132    12537572    12537569    17372656    18327897   

EMBL

BABH01013035    DQ497197    DQ443289    JTDY01002647    KOB71008.1    GDQN01007951    + More
JAT83103.1    KQ460883    KPJ11350.1    AK401618    KQ459586    BAM18240.1    KPI97930.1    GAIX01013831    JAA78729.1    AGBW02012225    OWR45401.1    ODYU01000441    SOQ35218.1    ODYU01000442    SOQ35219.1    GEZM01032198    JAV84776.1    KQ971371    EFA10249.1    LJIG01022474    KRT80388.1    JXUM01092979    GAPW01003260    KQ564025    JAC10338.1    KXJ72905.1    GAPW01003259    JAC10339.1    GBYB01014119    GBYB01014120    JAG83886.1    JAG83887.1    KQ435774    KOX75064.1    DQ440410    CH477408    CH477907    APGK01017186    BT128346    KB739998    KB631984    AEE63304.1    ENN81948.1    ERL87637.1    KZ288217    PBC32419.1    JR041008    AEY59341.1    KK852801    KDR16317.1    GECZ01015448    JAS54321.1    GECZ01018196    JAS51573.1    GECU01025102    JAS82604.1    GECU01014547    JAS93159.1    GL439158    EFN67683.1    LBMM01001115    KMQ96901.1    KQ976619    KYM79135.1    DS231815    ADTU01025202    GL888322    EGI62808.1    GFDL01012932    JAV22113.1    KQ434824    KZC07349.1    GALA01000953    JAA93899.1    KQ414672    KOC64189.1    KQ976574    KYM80100.1    KQ981387    KYN41976.1    GL888327    EGI62735.1    KQ982294    KYQ58331.1    AJVK01026943    KK107054    EZA61411.1    ADTU01015424    QOIP01000004    RLU24172.1    KQ976973    KYN06655.1    NEVH01009770    PNF32743.1    GFDF01004907    JAV09177.1    GFDF01004779    JAV09305.1    KQ980447    KYN16004.1    KQ980653    KYN14840.1    KYN14841.1    KQ977305    KYN03772.1    APCN01000220    AAAB01008807    UFQT01000264    SSX22560.1    ATLV01012364    KE524785    KFB36620.1    KQ762520    OAD55758.1    AXCM01000560    GBBI01000685    JAC18027.1    AXCN02000591    GBHO01001985    GBRD01011867    GDHC01012405    JAG41619.1    JAG53957.1    JAQ06224.1    GGFJ01008234    MBW57375.1    GDKW01000496    JAI56099.1    ACPB03001010    GAHY01001142    JAA76368.1    GBHO01001986    JAG41618.1    GGFM01006549    MBW27300.1    GECL01003527    JAP02597.1    NNAY01001594    OXU23486.1    ADMH02001104    ETN64097.1    GBGD01002423    JAC86466.1    KQ981923    KYN32922.1    GFTR01004561    JAW11865.1    GL764659    EFZ17316.1    CH983411    CH480825    AE014298    AY118933    GDHF01016225    GDHF01000841    JAI36089.1    JAI51473.1    GAMD01000635    JAB00956.1    CH940655    GANO01001750    JAB58121.1    CH963925    CH933812    CM000162    CH954183    CH902632   

Proteomes

UP000005204    UP000037510    UP000053240    UP000053268    UP000007151    UP000007266    + More
UP000192223    UP000069940    UP000249989    UP000053105    UP000008820    UP000019118    UP000030742    UP000005203    UP000242457    UP000027135    UP000000311    UP000036403    UP000078540    UP000002320    UP000005205    UP000007755    UP000076502    UP000053825    UP000078541    UP000075809    UP000092462    UP000053097    UP000279307    UP000078542    UP000235965    UP000078492    UP000075920    UP000075903    UP000076407    UP000075882    UP000075840    UP000007062    UP000075902    UP000075884    UP000075901    UP000030765    UP000076408    UP000075883    UP000075885    UP000075886    UP000015103    UP000075881    UP000215335    UP000000673    UP000075900    UP000075880    UP000000304    UP000001292    UP000002358    UP000000803    UP000008792    UP000007798    UP000009192    UP000002282    UP000008711    UP000192221    UP000007801   

PRIDE

I1E4Y7    Q1HE00    A0A088AKE0    B0VZS1    Q9W4X7    B4MA85    + More
B4N1L0    B4L710   

Pfam

PF12353   eIF3g        + More
PF00076   RRM_1

Interpro

IPR000504   RRM_dom        + More
IPR012677   Nucleotide-bd_a/b_plait_sf       
IPR034240   eIF3G_RRM       
IPR024675   eIF3g_N       
IPR017334   eIF3_g       
IPR035979   RBD_domain_sf       

SUPFAM

SSF54928   SSF54928       

Gene 3D

3.30.70.330    

CDD

cd12933  eIF3G
cd12408  RRM_eIF3G_like

ProteinModelPortal

I1E4Y7   Q1HE00   A0A0L7L659   A0A1E1W806   A0A194R272   I4DK00   + More
S4NNR3   A0A212EVB0   A0A2H1V301   A0A2H1V345   A0A1Y1MLK1   D6X2C9   A0A0T6AZL2   A0A1W4XT48   A0A023EM15   A0A023EPC6   A0A0C9RXY2   A0A0N0BGU7   Q1HQN4   J3JYL7   A0A088AKE0   A0A2A3EMN6   V9IFS5   A0A067R0P4   A0A1B6FW19   A0A1B6FNI9   A0A1B6I6P7   A0A1B6J1U9   E2AFT4   A0A0J7L2I9   A0A151I0E9   B0VZS1   A0A158NSV4   F4WSJ3   A0A1Q3F3J5   A0A154P602   T1D4I0   A0A0L7QZZ0   A0A195B766   A0A195FNG2   F4WSS8   A0A151XD87   A0A1B0D7I8   A0A026X073   A0A158NH11   A0A3L8DV23   A0A195D168   A0A2J7QVY4   A0A1L8DS20   A0A1L8DSK7   A0A151J1Y4   A0A182WIV3   A0A195DPJ2   A0A195CTE5   A0A182VJ14   A0A182X6H9   A0A182KRX7   A0A182I3T1   Q7QJV0   A0A182UCM9   A0A336LXM6   A0A182NHF8   A0A182SXF5   A0A084VF76   A0A310S9W8   A0A182XZF5   A0A182MUR1   A0A182P9X5   A0A023F956   A0A182Q3J3   A0A0A9ZB41   A0A2M4BWB6   A0A0P4VNA1   R4G8D9   A0A0A9ZE63   A0A182JQV0   A0A2M3ZFU2   A0A0V0G5N9   A0A232EYC6   W5JI77   A0A069DRY2   A0A182RB50   A0A182J9H1   A0A195EYD7   A0A224XHA2   E9IPX0   B4NTY9   B4I9X1   K7IM65   Q9W4X7   A0A0K8VAW6   T1DRG8   B4MA85   U5EKM3   B4N1L0   B4L710   B4Q0Y7   B3P935   A0A1W4V9Y2   B3MYX2  

PDB

6FYY     E-value=1.23101e-22,     Score=261

KEGG

732971    K03248 translation initiation factor 3 subunit G | (RefSeq) eIF3g, eIF3-S4; Eukaryotic translation i

PATHWAY

03013    RNA transport - Bombyx mori (domestic silkworm)

GO

GO:0003743   GO:0005852   GO:0001732   GO:0016282   GO:0033290   GO:0003729   GO:0000278   GO:0006413   GO:0003676   GO:0005737   GO:0000166   GO:0048869   GO:0016491   GO:0015930  

Subcellular location

Cytoplasm  

Length:

274

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0

Exp number, first 60 AAs:

0

Total prob of N-in:

0.01373

outside

1  -  274

 

 

Pi

178.492636

Theta

173.282723

Tajima's D

0.311234

CLR

0.004047

CSRT

0.459577021148943

Interpretation

Uncertain