Gene

KWMTBOMO13168  Validated by peptides from experiments

Pre Gene Modal

BGIBMGA000368

Annotation

cytochrome_P450_302A1_[Bombyx_mori]

Location

Bomo_Chr22(-):9474715-9483692      View in EpiBrowser

Location in the cell

Mitochondrial   Reliability : 2.25

CDS

ATGTTTGTTAGATTAACAGTTAAAAATAATATTCCCTACCGGGCGAGGAAATGTGTTTACAGAAGAGCGTCTGAAAATTTTGTGGGTAGTGAACATGCCAGTAAGGTCAATGAACAGGGAGATAATCTCATGAATTTCGAAGATATACCGGGACCTCGAAGCTATCCCATTATTGGTACGCTTCATAAATACCTACCTTTAATTGGTGACTATGACGCCGAAGCTTTAGATAAGAATGCAATATTGAATTGGCGACGTTATGGTAGCTTAGTTAGAGAAAAACCGATTGTCAATTTAGTCCATGTTTATGATCCGGATGACATTGAGGCGGTGTTCCGACAAGACCACCGCTATCCAGCGAGGCGCAGTCATACCGCTATGAACTACTACAGAACCAACAAACCGAATGTGTACAACACTGGAGGACTTCTTGCGACCAACGGACCCGATTGGTGGAGACTCAGAAGCATATTTCAAAAGAATTTCACGAGTCCACAAAGTGTTAAAACTCACGTCTCTGACACCGATAATATCGCAAAAGAATTCGTTGAGTGGATCAAAAGAGACAAGGTGTCATCTAAAAATGATTTTTTGACGTTTCTAAATCGCCTTAACTTAGAAATCATAGGTGTAGTAGCTTTTAACGAACGTTTCAATAGTTTCGCTTTGAGCGAGCAAGATCCCGAGAGTCGCAGCAGCAAAACGATAGCGGCAGCATTCGGATCAAATTCTGGGGTCATGAAGCTTGATAAAGGATTTCTCTGGAAAATGTTTAGTACTCCACTATACAAGAAACTCGTGAATTCTCAAATCTATTTAGAAAAAATTTCCACAGATATATTGATTAGAAAGATTAATCTCTTCGAATCCGATGATAGTAAAAACGATAAATCTTTGTTAAAAACATTTCTTCAACAACCCCAGCTGGATCACAAGGATATCATGGGAATGATGGTTGATATTCTAATGGCTGCAATCGATACAACAGCCTACACGACAAGCTTCGTATTGTACCATATAGCCCGTAATAAGAGATGCCAGGACGAAATGTTTGAAGAGCTACATACATTATTACCAAAGAAAGATGATGAGATAACCGCTGACGTTCTTTCTAAAGCTTCATACGTGAGAAGCAGTATTAAAGAGAGTTTGAGACTTAATCCGGTATCGATTGGAATAGGTAGATGGCTGCAGAAGGATATAGTTTTAAAAGGATATTCCATTCCTAAGGGAACTGTTATAGTGACGCAGAACATGACGTCATCAAGGTTGCCGCAGTTTATACGGGACCCCTTAACCTTCAAGCCTGAACGTTGGATGCGTGGTTCACCGCAATACGAGACCATTCATCCGTTTCTGAGCTTGCCTTTTGGTCACGGGCCCCGTTCGTGTATTGCAAGAAGACTGGCCGAGCAAAATATTTGCATTATCTTAATGAGGTTAATTCGTGAGTTTGAAATCCAATGGGCCGGCGAGGAGCTTGGAGTGAAGACACTGCTTATAAATAAACCAAACAAACCTGTATCACTAAACTTTATTCCAAGAAGTAGTTAA

Protein

MFVRLTVKNNIPYRARKCVYRRASENFVGSEHASKVNEQGDNLMNFEDIPGPRSYPIIGTLHKYLPLIGDYDAEALDKNAILNWRRYGSLVREKPIVNLVHVYDPDDIEAVFRQDHRYPARRSHTAMNYYRTNKPNVYNTGGLLATNGPDWWRLRSIFQKNFTSPQSVKTHVSDTDNIAKEFVEWIKRDKVSSKNDFLTFLNRLNLEIIGVVAFNERFNSFALSEQDPESRSSKTIAAAFGSNSGVMKLDKGFLWKMFSTPLYKKLVNSQIYLEKISTDILIRKINLFESDDSKNDKSLLKTFLQQPQLDHKDIMGMMVDILMAAIDTTAYTTSFVLYHIARNKRCQDEMFEELHTLLPKKDDEITADVLSKASYVRSSIKESLRLNPVSIGIGRWLQKDIVLKGYSIPKGTVIVTQNMTSSRLPQFIRDPLTFKPERWMRGSPQYETIHPFLSLPFGHGPRSCIARRLAEQNICIILMRLIREFEIQWAGEELGVKTLLINKPNKPVSLNFIPRSS

Similarity

Belongs to the cytochrome P450 family.

Uniprot

Q4W6L7   L0N4M8   L0N5I2   Q2HZZ5   A0A2A4IZQ5   A0A068ETR0   + More
A0A248QJ96   A0A0P0HQW7   D1FV85   A0A194PX77   A0A286MXN1   S6BQ30   A0A194R0N2   A0A212EV70   A0A0L7L6P3   A0A1V0D9G6   X5DQS7   A0A2H1VDT0   V5K560   E2C0K4   A0A1Y1MQZ5   A0A1B6KHD3   A0A1U9JI15   A0A232EYJ5   K7J0E9   A0A310SF61   A0A2J7QSJ5   A0A1B6K6T8   E2AS82   A0A2S2QVT1   A0A088A954   A0A151WVI9   A0A195AXG9   E0VJJ0   N6ULJ9   A0A158NFS1   D6WNV9   A0A0M3RSR8   A0A1S4EL89   A0A182P5K6   F4X0C4   A0A151JX51   U4UNU3   A0A182I1S9   A0A182X753   A9Q616   Q7PNR4   A0A067QQ08   A0A3L8DEW4   A0A182UUR0   A0A195D6Z7   A0A182K852   A0A151IYB7   W8CDG2   Q16Q15   A0A2J7QSI5   Q563C7   A0A0P5SY38   A0A182REH4   A0A182WKL2   Q1DGF4   A0A1S4FTE7   A0A0P6ISL7   A0A0A1XI28   B3M5G2   A0A0K8UAD1   A0A182FCN5   A0A034W0M9   A0A0M3QVV0   K9LCM2   A0A0M4ECC1   A0A182QJZ5   A0A164T988   A0A182YCY6   B4K0U9   B0WV99   A0A3B0KF69   A0A182NIJ1   R4I4N1   A0A2H8TFM0   A0A0P5CR42   E9HYW3   A0A1A9V4A9   B3NG26   A0A0P4ZF62   A0A1A9ZRZ5   B4LED3   A0A026WT04   A0A0P5GDS8   A0A068F785   A0A1B0FV58   A0A1A9YEJ7   A0A1B0B7U0   A0A0P5SPD3   A0A1B0FGR0   B4N6A1   A0A1A9W4R6   Q2LZW4   A0A336KNN7  

Pubmed

16164612    19121390    16503480    28881445    19682519    26354079    + More
19954531    25299618    22118469    26227816    24361403    24267698    20798317    28004739    28648823    20075255    20566863    23537049    21347285    18362917    19820115    26319543    21719571    19060216    12364791    14747013    17210077    24845553    30249741    24495485    17510324    15804580    25830018    17994087    25348373    25244985    21292972    24508170    25880816    15632085   

EMBL

BABH01013035    AB198340    AK289323    BAD99022.1    BAM73850.1    AK289322    + More
BAM73849.1    AK289321    BAM73848.1    DQ357067    ABC96069.1    NWSH01004915    PCG64593.1    KM016700    AID54852.1    KX443476    ASO98051.1    KP764853    ALJ84051.1    FJ403324    ACM46003.1    KQ459586    KPI97927.1    MF684349    ASX93983.1    AB649118    BAN66312.1    KQ460883    KPJ11353.1    AGBW02012225    OWR45398.1    JTDY01002647    KOB71009.1    KY212062    ARA91626.1    KF701183    AHW57353.1    ODYU01002025    SOQ39020.1    KF044270    AGT57842.1    GL451800    EFN78521.1    GEZM01028188    JAV86396.1    GEBQ01029100    JAT10877.1    KY404120    AQR58054.1    NNAY01001637    OXU23357.1    KQ761824    OAD56756.1    NEVH01011876    PNF31554.1    GECU01017605    GECU01015769    GECU01000539    JAS90101.1    JAS91937.1    JAT07168.1    GL442229    EFN63712.1    GGMS01012645    MBY81848.1    KQ982699    KYQ51949.1    KQ976716    KYM76886.1    DS235222    EEB13546.1    APGK01018911    KB740085    ENN81546.1    ADTU01014663    KQ971343    EFA04695.1    KR012856    ALD15931.1    GL888497    EGI60082.1    KQ981620    KYN39222.1    KB632303    ERL91811.1    APCN01000092    EF546763    ABU42523.1    AAAB01008960    EAA11728.5    KK853069    KDR11805.1    QOIP01000009    RLU18732.1    KQ976750    KYN08648.1    KQ980784    KYN13174.1    GAMC01002001    JAC04555.1    CH477766    EAT36461.1    PNF31552.1    AY947549    AAX85205.1    GDIP01133588    JAL70126.1    CH902195    EAT32233.1    GDIQ01005974    JAN88763.1    GBXI01013389    GBXI01011708    GBXI01003717    JAD00903.1    JAD02584.1    JAD10575.1    CH902618    EDV39572.1    GDHF01028756    JAI23558.1    GAKP01011629    JAC47323.1    CP012525    ALC43029.1    JF835064    AFH54200.1    ALC43046.1    AXCN02000482    LRGB01001863    KZS10280.1    CH916577    EDV90410.1    DS232121    EDS35442.1    OUUW01000009    SPP84959.1    JQ027284    AFI80734.1    GFXV01001035    MBW12840.1    GDIP01170683    JAJ52719.1    GL733233    EFX63066.1    CH954178    EDV50855.1    GDIP01213520    JAJ09882.1    CH940647    EDW70109.1    KK107119    EZA58811.1    GDIQ01242936    GDIP01090093    JAK08789.1    JAM13622.1    KJ702305    AID61459.1    AJWK01010387    JXJN01009718    GDIP01140594    JAL63120.1    CCAG010018926    CH964154    EDW79890.1    CH379069    EAL31173.2    UFQS01000676    UFQT01000676    SSX06089.1    SSX26445.1   

Proteomes

UP000005204    UP000218220    UP000053268    UP000053240    UP000007151    UP000037510    + More
UP000008237    UP000215335    UP000002358    UP000235965    UP000000311    UP000005203    UP000075809    UP000078540    UP000009046    UP000019118    UP000005205    UP000007266    UP000079169    UP000075885    UP000007755    UP000078541    UP000030742    UP000075840    UP000076407    UP000007062    UP000027135    UP000279307    UP000075903    UP000078542    UP000075881    UP000078492    UP000008820    UP000075900    UP000075920    UP000007801    UP000069272    UP000092553    UP000075886    UP000076858    UP000076408    UP000001070    UP000002320    UP000268350    UP000075884    UP000000305    UP000078200    UP000008711    UP000092445    UP000008792    UP000053097    UP000092461    UP000092443    UP000092460    UP000092444    UP000007798    UP000091820    UP000001819   

PRIDE

Q4W6L7    L0N4M8    L0N5I2   

Pfam

PF00067   p450        + More
PF00814   Peptidase_M22

Interpro

IPR036396   Cyt_P450_sf        + More
IPR017972   Cyt_P450_CS       
IPR001128   Cyt_P450       
IPR002403   Cyt_P450_E_grp-IV       
IPR002401   Cyt_P450_E_grp-I       
IPR000905   Gcp-like_dom       
IPR017861   KAE1/TsaD       

SUPFAM

SSF48264   SSF48264       

Gene 3D

1.10.630.10    

ProteinModelPortal

Q4W6L7   L0N4M8   L0N5I2   Q2HZZ5   A0A2A4IZQ5   A0A068ETR0   + More
A0A248QJ96   A0A0P0HQW7   D1FV85   A0A194PX77   A0A286MXN1   S6BQ30   A0A194R0N2   A0A212EV70   A0A0L7L6P3   A0A1V0D9G6   X5DQS7   A0A2H1VDT0   V5K560   E2C0K4   A0A1Y1MQZ5   A0A1B6KHD3   A0A1U9JI15   A0A232EYJ5   K7J0E9   A0A310SF61   A0A2J7QSJ5   A0A1B6K6T8   E2AS82   A0A2S2QVT1   A0A088A954   A0A151WVI9   A0A195AXG9   E0VJJ0   N6ULJ9   A0A158NFS1   D6WNV9   A0A0M3RSR8   A0A1S4EL89   A0A182P5K6   F4X0C4   A0A151JX51   U4UNU3   A0A182I1S9   A0A182X753   A9Q616   Q7PNR4   A0A067QQ08   A0A3L8DEW4   A0A182UUR0   A0A195D6Z7   A0A182K852   A0A151IYB7   W8CDG2   Q16Q15   A0A2J7QSI5   Q563C7   A0A0P5SY38   A0A182REH4   A0A182WKL2   Q1DGF4   A0A1S4FTE7   A0A0P6ISL7   A0A0A1XI28   B3M5G2   A0A0K8UAD1   A0A182FCN5   A0A034W0M9   A0A0M3QVV0   K9LCM2   A0A0M4ECC1   A0A182QJZ5   A0A164T988   A0A182YCY6   B4K0U9   B0WV99   A0A3B0KF69   A0A182NIJ1   R4I4N1   A0A2H8TFM0   A0A0P5CR42   E9HYW3   A0A1A9V4A9   B3NG26   A0A0P4ZF62   A0A1A9ZRZ5   B4LED3   A0A026WT04   A0A0P5GDS8   A0A068F785   A0A1B0FV58   A0A1A9YEJ7   A0A1B0B7U0   A0A0P5SPD3   A0A1B0FGR0   B4N6A1   A0A1A9W4R6   Q2LZW4   A0A336KNN7  

PDB

3K9Y     E-value=7.2223e-43,     Score=439

KEGG

692499    K10721 ecdysteroid 22-hydroxylase | (RefSeq) Cyp302a1, Dib; cytochrome P450 302A1

PATHWAY

00981    Insect hormone biosynthesis - Bombyx mori (domestic silkworm)

GO

GO:0004497   GO:0005506   GO:0016705   GO:0020037   GO:0004501   GO:0046872   GO:0008258   GO:0042767   GO:0008362   GO:0007417   GO:0007391   GO:0007494   GO:0005739   GO:0006697   GO:0005634   GO:0005737   GO:0048869   GO:0003676   GO:0016491   GO:0015930   GO:0055114  

Length:

517

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

7.83689

Exp number, first 60 AAs:

7e-05

Total prob of N-in:

0.01423

outside

1  -  517

 

 

Pi

234.552194

Theta

195.968588

Tajima's D

0.34805

CLR

0.379809

CSRT

0.464026798660067

Interpretation

Uncertain