Gene

KWMTBOMO13148

Annotation

reverse_transcriptase_[Bombyx_mori]

Location

Bomo_Chr22(+):9190863-9195689      View in EpiBrowser

Full name

Probable RNA-directed DNA polymerase from transposon BS       + More
Probable RNA-directed DNA polymerase from transposon X-element      

Alternative Name

Reverse transcriptase

Location in the cell

Nuclear   Reliability : 2.111

CDS

ATGGAGTCCACGATCGATCTGTTCGCGGAATTCCTCCGTCTGAGGTACCCGACATTATCGGCCGAATTTTTAGAATTTGAGGCCAATCACGCCGCGAACTCAGAAGCGGTCTCCGTCGCGCCCGCCGCTCCCGTGTCCCCAATACTCGCGAGCAAAGCTCCCGCGTCGATCGCTGCGCTCTCGGTTCCAGCCCTGCGCTCATCCGCAGCACACGTCGCGTCCACGCGTTCATCCGCGGCCTCCATCGCGCCCGCGCCGTCCTGTGCCCCCGAGCGATTGTCCGTGGCTTCCGTCGCGACCGTCAACCCCGCGCCCTCTAAAACGCCCGCCTGCGGGTCGCCCGCGCCCTCCTCTTCATCCTACTCGGAGTCGGACATGGAGGTCGATCTTTCCCCCGCCTCCTCGACTGATGGATTCACAGTAGTCCAAAAAGGTAAGAGGCGCGCTGCGGAAGCCCGAGCTCCCGCGGCCGCCAAAGAGGAGCGCGAACTTCGTGCCGTCATACGTGGCATCCCTAAAGAGTTGGATGCCGAACTCGTCAAGGCCGACCTTCTGGAGCAAGGCCTACCAGTAAATTCAGTGCACCGCATGCACACCGGCCGCGGTAGGGAGCCATATAATATGGTTCTAGTCGCCCTCCAGCCTACCCCCGAGGTACAGGAGACTCTACTTAAGCCCGCGCGCCGCGACCCTAAAATCGCGAACTATAACATGGTTAGGAACGACAGGCTCACTGCTCGTGGTGGTGGTACCGTCATCTACTACAGAAGAGCCTTGCACTGCATCCCGCTCGTTAACATCGAAGCATCAGTATGCCGAATCTCACTGACGGGACACGCGCCGATCGTTATCGCGTCCGCTTATCTTCCACCGGATAAGATTGTTCTAAGCAGTGATATTGAGGCGCTGCTCAGCATGGGAAGCTCTGTCATTCTGGCGTGCGACCTAAATTGTAAACACATCAGGTGGAACTCTCACATCACAACCCCTAATGGCAGGCGGCTCGACGCGCTAGTCGATGATCTCGCCTTCGATGTCATCGCTCCGCTAAACCCGACTCACTACCCGCTAAATATCGCGCATCGTCCGGATATACTCGACATAGCGTTATTAAAAAACGTAGCTCTGCGCTTACACTCGATCGAAGTAGTTTCAGAGTTAGATTCAGACCACCGTCCCGTCGTTATGAAGCTCGGTCGCGCTCCCGATTCCGTTCCCGTCACGAGGACTGTAGTGGATTGGCACATGCTGGGCATCAGCCTGGCTGAATCTGATCCACCATCGCTCCCGTTTAGCCCGGACTCTACCCCGTCTCTTCAGGATACGGCTGAAGCCATAGACATCCTAACGTCACACATTACCTCGACATTAGATAGGTCATCGAAGCAAGTTGTAGCGGAGGACTTTCTTCACCGCTTCGAATTGCCCGACGATATTAGGGAACTCCTTAGAGCTAAGAACGCTTCGATCCGCGCCTACGATAGGTATCCTACCGTGGAAAATCGTATTCGAATGCGTGCCTTACAACGCGACGTAAAGTCTCGCATCGCCGAAGTCCGAGATGCCAGGTGGTCTGATTTCTTAGAAGGACTCGCGCCCTCTCAAAGGTCTTACTACCGCTTAGCTCGTACTTTCAAATCGGATACGGTTGTAACTATGCCCCCCCTCGTAGGCCCCTCAGGTCGACTCGTGGCGTTTGATGATGACGAAAAAGCAGAGCTGCAGGCCGATACATTGCAAACCCAGTGCACGCCCAGCATTCAATCCGCGGACCCTGTTCATGTAGAATTGGTAGACAGTGAGGTAGAACGCAGAGCCTCCTTGCCACCCTCGGATGCGTTACCACCCGTCACCCCGATGGAAGTTAAAGACTTGATCAAAGACCTACGTCCTCGCAAGGCTCCCGGTTCCGACGGTATATCTAACCGCGTTATTAAACTTCTACCCATCCAACTCATCGTGATGTTGGCATCTATTTTCAATGCCGCTATGGCGAACTGTATCTTTCCCGCGGTGTGGAAAGAAGCGGACGTTATCGGCATACATAAACCCGGTAAACCAAAAAATCATCCGACGAGTTACCGCCCGATTAGCCTCCTCATGTCTCTGGGCAAACTGTATGAGCGTTTGCTCTACAAACGCCTCAGAGACTTCGTCTCATCAAAGGGCATTCTCATCGATGAACAATTCGGATTCCGTGCAAATCACTCATGCGTACAACAGGTGCACCGCCTCACGGAGCACATTCTTGTAGGACTTAACCGACCAAAACCGATCTATACGGGAGCCCTCTTCTTCGACGTCGCAAAAGCGTTCGACAAAGTCTGGCACAACGGTTTGATTTTCAAACTTTTCAACATGGGCGTACCGGACAGTCTCGTGCTCATCATACGAGACTTCTTGTCTAACCGCTCTTTTCGATATCGAGTAGAGGGAACCCGCTCCTCCCCGCGACCACTCACGCCTGGAGTCCCGCAAGGCTCCGTTCTCTCTCCGCTCCTATTTAGTTTATTTATTAACGATATTCCCCGGTCGCCGCCGACCCAGCTAGCCTTATTCGCTGACGACACAACCGTTTACTACTCAAGTAGAAACAAGTCCCTAATCGCGAGTAAGCTCCAGAGTGCAGCGTTAACCCTCGGACAGTGGTTCCGAAAATGGCGCATAGACATCAACCCAGCGAAAAGCACAGCAGTGTTATTTCAAAGGGGAAACTCACCGCTTATTTCCTCCCGCATTAGGAGGAGAAATATCACACCCCCGATCACCCTCTTCGGCCAACCTATACTAGGATATCCAACCTGGGCTAGGAAGGTCAAGTACCTGGGAGTCACCCTGGATGCATCTATGACATTCCGCCCGCATATAAAAACAGTTCGCGATCGTGCCGCATTTATTCTCGGCAGACTCTATCCCATGATCTGTAAGCGGAGTAAAATGTCCCTTCGGAACAAGGTGACACTTTACAAAACTTGCATAAGGCCCGTCATGACTTACGCGAGTGTGGTGTTCGCTCACGCGGCCCGCACACACATAGACACCCTCCAATCCCTACAATCCCGCTTTTGCAGGTTAGCCGTCGGGGCTCCGTGGTTCGTGAGGAACGTCGACCTACACGACGACCTGGGCCTCGAATCGATCCGCAAACACATGAAGTCAGTGTCGGAACGTTACTTCGATAAGGCTATGCGTCATGATAATCGCCTTATCGTAGCCGCCGCTGACTACTCCCCGAATCCTGATCACGCAGGAGCAAGTCACCGTCATCGCCCTAGACACGTCCTTACGGATCCATCAGATCCAATAACTCTTGCATTAGATACCTTCAGCTCTAACACTAGGAGCAGGCTGAGGAACCCCGGTAACCGTACTCGTCGAACTCGACAAAGAGGTCGACGTGCAGCCTAA

Protein

MESTIDLFAEFLRLRYPTLSAEFLEFEANHAANSEAVSVAPAAPVSPILASKAPASIAALSVPALRSSAAHVASTRSSAASIAPAPSCAPERLSVASVATVNPAPSKTPACGSPAPSSSSYSESDMEVDLSPASSTDGFTVVQKGKRRAAEARAPAAAKEERELRAVIRGIPKELDAELVKADLLEQGLPVNSVHRMHTGRGREPYNMVLVALQPTPEVQETLLKPARRDPKIANYNMVRNDRLTARGGGTVIYYRRALHCIPLVNIEASVCRISLTGHAPIVIASAYLPPDKIVLSSDIEALLSMGSSVILACDLNCKHIRWNSHITTPNGRRLDALVDDLAFDVIAPLNPTHYPLNIAHRPDILDIALLKNVALRLHSIEVVSELDSDHRPVVMKLGRAPDSVPVTRTVVDWHMLGISLAESDPPSLPFSPDSTPSLQDTAEAIDILTSHITSTLDRSSKQVVAEDFLHRFELPDDIRELLRAKNASIRAYDRYPTVENRIRMRALQRDVKSRIAEVRDARWSDFLEGLAPSQRSYYRLARTFKSDTVVTMPPLVGPSGRLVAFDDDEKAELQADTLQTQCTPSIQSADPVHVELVDSEVERRASLPPSDALPPVTPMEVKDLIKDLRPRKAPGSDGISNRVIKLLPIQLIVMLASIFNAAMANCIFPAVWKEADVIGIHKPGKPKNHPTSYRPISLLMSLGKLYERLLYKRLRDFVSSKGILIDEQFGFRANHSCVQQVHRLTEHILVGLNRPKPIYTGALFFDVAKAFDKVWHNGLIFKLFNMGVPDSLVLIIRDFLSNRSFRYRVEGTRSSPRPLTPGVPQGSVLSPLLFSLFINDIPRSPPTQLALFADDTTVYYSSRNKSLIASKLQSAALTLGQWFRKWRIDINPAKSTAVLFQRGNSPLISSRIRRRNITPPITLFGQPILGYPTWARKVKYLGVTLDASMTFRPHIKTVRDRAAFILGRLYPMICKRSKMSLRNKVTLYKTCIRPVMTYASVVFAHAARTHIDTLQSLQSRFCRLAVGAPWFVRNVDLHDDLGLESIRKHMKSVSERYFDKAMRHDNRLIVAAADYSPNPDHAGASHRHRPRHVLTDPSDPITLALDTFSSNTRSRLRNPGNRTRRTRQRGRRAA

Catalytic Activity

a 2'-deoxyribonucleoside 5'-triphosphate + DNA(n) = diphosphate + DNA(n+1)

Cofactor

Mg(2+)
Mn(2+)

Miscellaneous

At least 30 copies of X-element are present in the genome and some elements are polymorphic between different strains.

Keywords

Nucleotidyltransferase   RNA-directed DNA polymerase   Transferase   Transposable element  

Feature

chain  Probable RNA-directed DNA polymerase from transposon BS

Uniprot

Q9XXW0   Q93137   Q9BPQ0   A0A0N1PFV1   O96546   A0A1Y1NA23   + More
V5GNJ2   A0A139WA11   A0A139W8G9   V5GNF3   X1WLB2   A0A023EYS8   A0A2S2PPK8   X1WNI2   J9LC21   X1WZH0   A0A2S2QEE0   A0A224XF24   A0A023EZE6   A0A2J7PQB5   A0A224XB44   A0A224X6Q4   K7IN67   A0A1Y1LKN6   A0A2J7R7D0   J9M522   A0A2S2Q383   A0A2J7QR37   A0A2J7PBY3   A0A2J7QY69   A0A2J7PU96   A0A2M4CV52   J9LFC9   A0A2M4CV42   A0A224XI99   A0A0A9YJ00   A0A2S2NGV8   A0A224X6U5   A0A3N5Z7I3   A0A087UGF5   A0A2M4BDV6   A0A224X6S1   A0A2M4BD67   A0A0A9YU04   Q07995   A0A2J7PDM0   A0A2J7Q6J2   A0A1Y1KFR3   A0A224X6T4   A0A2M4BD83   A0A2S2N814   A0A2M4BD66   A0A2M4BDA5   A0A2M4BD62   A0A224XJI0   A0A2J7PVX3   A0A023F069   A0A2S2NH02   A0A2S2PJG2   A0A069DZL8   A0A2J7QB68   Q95SX7   A0A2S2N6Q7   A0A142LX49   A0A2S2P6S3   A0A2S2R9D4   A0A224X746   A0A1B6EGD8   A0A224XIB0   A0A352X8G4   A0A0V0G5B6   A0A2A4K918   Q8T9X4   A0A1Q3G5J4   A0A2M4CVK2   A0A2H8TF37   Q8I7P8   Q9NBX4   A0A2S2NPG3   A0A224X6R6   A0A2M4CVF1   A0A087UCW3  

EC Number

2.7.7.49

Pubmed

10333566    26354079    10380107    28004739    18362917    19820115    + More
25474469    20075255    25401762    30086797    8387152    26334808    7753626    12537569    25527032    30148503    11405632   

EMBL

AB018558    BAA76304.1    U07847    AAA17752.1    AB055391    BAB21761.1    + More
KQ459265    KPJ02064.1    AF081103    AAC72921.1    GEZM01008457    JAV94772.1    GALX01005299    JAB63167.1    KQ971729    KYB24751.1    KQ973342    KXZ75569.1    GALX01005359    JAB63107.1    ABLF02042518    ABLF02057746    GBBI01004395    JAC14317.1    GGMR01018716    MBY31335.1    ABLF02008153    ABLF02008462    ABLF02008464    ABLF02036316    ABLF02036319    ABLF02048663    ABLF02066977    ABLF02034467    GGMS01006359    MBY75562.1    GFTR01008038    JAW08388.1    GBBI01004571    JAC14141.1    NEVH01022639    PNF18527.1    GFTR01008262    JAW08164.1    GFTR01008279    JAW08147.1    GEZM01053022    JAV74219.1    NEVH01006736    PNF36716.1    ABLF02024246    GGMS01002992    MBY72195.1    NEVH01011985    PNF31054.1    NEVH01027074    PNF13841.1    NEVH01009134    PNF33528.1    NEVH01021205    PNF19912.1    GGFL01004957    MBW69135.1    ABLF02023911    GGFL01005012    MBW69190.1    GFTR01008256    JAW08170.1    GBHO01010547    GBHO01010546    JAG33057.1    JAG33058.1    GGMR01003407    MBY16026.1    GFTR01008251    JAW08175.1    RPOV01000134    RPJ78669.1    KK119692    KFM76444.1    GGFJ01001857    MBW50998.1    GFTR01008271    JAW08155.1    GGFJ01001858    MBW50999.1    GBHO01021814    GBHO01010549    JAG21790.1    JAG33055.1    S59870    AAB26437.2    NEVH01026386    PNF14434.1    NEVH01017470    PNF24199.1    GEZM01084969    JAV60363.1    GFTR01008261    JAW08165.1    GGFJ01001822    MBW50963.1    GGMR01000676    MBY13295.1    GGFJ01001844    MBW50985.1    GGFJ01001842    MBW50983.1    GGFJ01001843    MBW50984.1    GFTR01008257    JAW08169.1    NEVH01020940    PNF20481.1    GBBI01003810    JAC14902.1    GGMR01003864    MBY16483.1    GGMR01016905    MBY29524.1    GBGD01000415    JAC88474.1    NEVH01016302    PNF25823.1    AY060438    AAL25477.1    GGMR01000226    MBY12845.1    KU543685    AMS38375.1    GGMR01012443    MBY25062.1    GGMS01017365    MBY86568.1    GFTR01008151    JAW08275.1    GEDC01000337    JAS36961.1    GFTR01008246    JAW08180.1    DNOY01000259    HBE18313.1    GECL01003538    JAP02586.1    NWSH01000032    PCG80496.1    AF456125    AAL57609.1    GFDL01000006    JAV35039.1    GGFL01005121    MBW69299.1    GFXV01000908    MBW12713.1    AY180919    AAN87272.1    AF237761    AAF81411.1    GGMR01006408    MBY19027.1    GFTR01008269    JAW08157.1    GGFL01005122    MBW69300.1    KK119261    KFM75202.1   

Proteomes

UP000053268    UP000007266    UP000007819    UP000235965    UP000002358    UP000054359    + More
UP000218220   

PRIDE

Q9XXW0    Q93137    Q9BPQ0    Q95SX7    Q8T9X4    Q8I7P8    + More
Q9NBX4   

Pfam

PF14529   Exo_endo_phos_2        + More
PF00078   RVT_1
PF07530   PRE_C2HC
PF03372   Exo_endo_phos
PF07727   RVT_2

Interpro

IPR000477   RT_dom        + More
IPR005135   Endo/exonuclease/phosphatase       
IPR036691   Endo/exonu/phosph_ase_sf       
IPR006579   Pre_C2HC_dom       
IPR013103   RVT_2       

SUPFAM

SSF56219   SSF56219       

Gene 3D

3.60.10.10    

ProteinModelPortal

Q9XXW0   Q93137   Q9BPQ0   A0A0N1PFV1   O96546   A0A1Y1NA23   + More
V5GNJ2   A0A139WA11   A0A139W8G9   V5GNF3   X1WLB2   A0A023EYS8   A0A2S2PPK8   X1WNI2   J9LC21   X1WZH0   A0A2S2QEE0   A0A224XF24   A0A023EZE6   A0A2J7PQB5   A0A224XB44   A0A224X6Q4   K7IN67   A0A1Y1LKN6   A0A2J7R7D0   J9M522   A0A2S2Q383   A0A2J7QR37   A0A2J7PBY3   A0A2J7QY69   A0A2J7PU96   A0A2M4CV52   J9LFC9   A0A2M4CV42   A0A224XI99   A0A0A9YJ00   A0A2S2NGV8   A0A224X6U5   A0A3N5Z7I3   A0A087UGF5   A0A2M4BDV6   A0A224X6S1   A0A2M4BD67   A0A0A9YU04   Q07995   A0A2J7PDM0   A0A2J7Q6J2   A0A1Y1KFR3   A0A224X6T4   A0A2M4BD83   A0A2S2N814   A0A2M4BD66   A0A2M4BDA5   A0A2M4BD62   A0A224XJI0   A0A2J7PVX3   A0A023F069   A0A2S2NH02   A0A2S2PJG2   A0A069DZL8   A0A2J7QB68   Q95SX7   A0A2S2N6Q7   A0A142LX49   A0A2S2P6S3   A0A2S2R9D4   A0A224X746   A0A1B6EGD8   A0A224XIB0   A0A352X8G4   A0A0V0G5B6   A0A2A4K918   Q8T9X4   A0A1Q3G5J4   A0A2M4CVK2   A0A2H8TF37   Q8I7P8   Q9NBX4   A0A2S2NPG3   A0A224X6R6   A0A2M4CVF1   A0A087UCW3  

PDB

6AR3     E-value=0.028518,     Score=92

KEGG

105842121    no KO assigned | (RefSeq) uncharacterized LOC105842121

GO

GO:0003964   GO:0004519   GO:0006313  

Length:

1135

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

2.84129

Exp number, first 60 AAs:

0.00078

Total prob of N-in:

0.00026

outside

1  -  1135

 

 

Pi

0

Theta

0

Tajima's D

0

CLR

215.027914

CSRT

0

Interpretation

Uncertain