Gene

KWMTBOMO13109

Pre Gene Modal

BGIBMGA000386

Annotation

PREDICTED:_glutamine_synthetase_2_cytoplasmic-like_[Amyelois_transitella]

Location

Bomo_Chr22(-):8472511-8474355      View in EpiBrowser

Full name

Glutamine synthetase       + More
Glutamine synthetase 2 cytoplasmic      

Alternative Name

Glutamate--ammonia ligase 2

Location in the cell

Extracellular   Reliability : 1.793

CDS

ATGAATTCCACACCGATTGCTTTGAACAAAGCGGCGATGCGCAAATATGAAGATCTGGAGGTGCCCTGCGATGCTATTTTGGCAAGTTACGTGTGGTTGGATGGTACTGGAATTAACCTCCGGTCAAAGGACAGAACCTTTGACTTCATACCTAAGGATCATAAAGATTTACCGATCTGGTACTTTGATGGCAGCAATACTGCGCAAGCTAACCCGGACAATTCCGACACGTTTATATTCCCCGAAGTGATTTACCACGACCCGTTTAGACGTGGAAACCACATATTAGTGTTAGCCGACACGTACCAGTTCAATTATCAGCCCACATCTAAACAAATGAGCTGTACTCCCGGAGATTTTCTAAAGAATCGAATGAAAGGAAGGGTTTTTGTGAAGGACGGTTGA

Protein

MNSTPIALNKAAMRKYEDLEVPCDAILASYVWLDGTGINLRSKDRTFDFIPKDHKDLPIWYFDGSNTAQANPDNSDTFIFPEVIYHDPFRRGNHILVLADTYQFNYQPTSKQMSCTPGDFLKNRMKGRVFVKDG

Catalytic Activity

ATP + L-glutamate + NH4(+) = ADP + H(+) + L-glutamine + phosphate

Subunit

Homooctamer.

Similarity

Belongs to the glutamine synthetase family.

Keywords

Alternative splicing   ATP-binding   Complete proteome   Cytoplasm   Ligase   Nucleotide-binding   Reference proteome  

Feature

chain  Glutamine synthetase 2 cytoplasmic
splice variant  In isoform A.

Uniprot

H9IT07   A0A3S2PC21   A0A194Q394   A0A212EZP4   A0A194R0T4   A0A2H1VSF8   + More
A0A2H1W4Y2   A0A2W1BMY2   A0A2A4J4U6   I4DRB2   A0A0G3VIA2   I4DJ32   S4PCI7   E5L9K5   H9J441   A0A1J1HER3   A0A034VVT9   A0A0K8VEK6   A0A2L1DH34   A0A0K8VUW5   A0A034VRN0   A0A336LVS2   A0A0A1XT45   A0A0A1WVL5   W8BUA3   A0A1B6LQ28   B4JIW8   A0A182RCW5   A0A182MEI4   W5JBC9   A0A1W7RAF9   A0A182VQ96   A0A1B6LT02   A0A1Y1KMB3   A0A182Q4C3   A0A182PA28   A0A182Y797   A0A182SDE2   A0A195C1J9   A0A182N4N2   B3MVR3   A0A1Q3G582   B4MCX6   D0QWE3   A0A182JIW4   A0A0Q9VZ95   A0A1B6DBW2   A0A1L8E2I2   V9IDX6   T1E8G9   A0A182F8N6   A0A0G2QRP6   A0A2M4AWJ3   A0A182U6F2   A0A182XIC8   A0A182LFG0   Q7QBX9   A0A182V4E1   F5HK76   A0A182HTB3   A0A088A2A8   A0A2A3E9Y7   A0A084VJR5   B4PYB1   X2JJG8   P20478   B3NUD5   P20478-3   Q494K4   A0A0R1EIC3   B4IK13   A0A1B0CM38   C8VV58   X2JDA5   A0A232EN32   A0A0Q5T3A2   A0A1W4V0I0   A0A3B0JXI0   T1GZS8   A0A1I9WLM6   A0A2I9LP19   Q29H28   B4H0G6   B4N1T9   D6WFH1   A0A3B0JXJ2   M9V250   A0A1W4UNL4   A0A2L2Y3Q9   A0A1B0B749   A0A1B0AIW9   A0A1A9Y1D7   A0A182K3Y7   A0A1A9UHR5   V5G3M6   D3TPP6   A0A1B6IB03   A0A087UK01   J3JTU0   A0A0P5P3X2  

EC Number

6.3.1.2

Pubmed

19121390    26354079    22118469    28756777    22651552    23622113    + More
20978910    25348373    25830018    24495485    17994087    20920257    23761445    28004739    25244985    19859648    20966253    12364791    14747013    17210077    24438588    17550304    10731132    12537568    12537572    12537573    12537574    16110336    17569856    17569867    26109357    26109356    1969491    12537569    28648823    27538518    29248469    15632085    18362917    19820115    26561354    20353571    22516182   

EMBL

BABH01013130    RSAL01000111    RVE47082.1    KQ459586    KPI97875.1    AGBW02011240    + More
OWR46960.1    KQ460883    KPJ11408.1    ODYU01004166    SOQ43749.1    ODYU01006294    SOQ48016.1    KZ150069    PZC74080.1    NWSH01003020    PCG67105.1    AK405048    BAM20452.1    KP657638    RSAL01000006    AKL78863.1    RVE54315.1    AK401300    BAM17922.1    GAIX01004181    JAA88379.1    HQ383986    ADQ64479.1    BABH01032611    CVRI01000001    CRK86464.1    GAKP01012982    JAC45970.1    GDHF01015334    JAI36980.1    KY681699    AVD29897.1    GDHF01009632    JAI42682.1    GAKP01012981    JAC45971.1    UFQS01000234    UFQT01000234    SSX01768.1    SSX22146.1    GBXI01000554    JAD13738.1    GBXI01011834    JAD02458.1    GAMC01006052    JAC00504.1    GEBQ01014179    JAT25798.1    CH916370    EDV99532.1    AXCM01011565    ADMH02001618    ETN61772.1    GFAH01000260    JAV48129.1    GEBQ01013233    JAT26744.1    GEZM01081263    GEZM01081262    JAV61728.1    AXCN02000052    KQ978379    KYM94490.1    CH902625    EDV35058.2    GFDL01000119    JAV34926.1    CH940660    EDW58048.1    FJ821026    ACN94650.1    KRF78088.1    GEDC01014152    JAS23146.1    GFDF01001163    JAV12921.1    JR039080    AEY58519.1    GAMD01002778    JAA98812.1    KC344400    AGY46258.1    GGFK01011804    MBW45125.1    AAAB01008859    EAA08219.5    EGK96917.1    APCN01000435    KZ288311    PBC28530.1    ATLV01013858    KE524905    KFB38209.1    CM000162    EDX01973.1    AE014298    AHN59592.1    X52759    AY060701    CH954180    EDV46050.1    BT023772    AAZ41780.1    KRK06487.1    CH480851    EDW51385.1    AJWK01018118    AJWK01018119    AJWK01018120    AJWK01018121    BT099804    ACV91641.1    AHN59591.1    NNAY01003212    OXU19783.1    KQS29805.1    OUUW01000011    SPP86775.1    CAQQ02099109    KU932410    APA34046.1    GFWZ01000141    MBW20131.1    CH379064    EAL31931.1    CH479200    EDW29761.1    CH963925    EDW78328.1    KQ971327    EEZ99821.1    SPP86774.1    KC445137    AGJ70738.1    IAAA01000603    LAA02791.1    JXJN01009401    GALX01003841    JAB64625.1    CCAG010007360    EZ423398    ADD19674.1    GECU01023633    JAS84073.1    KK120178    KFM77690.1    BT126649    AEE61612.1    GDIQ01133952    JAL17774.1   

Proteomes

UP000005204    UP000283053    UP000053268    UP000007151    UP000053240    UP000218220    + More
UP000183832    UP000001070    UP000075900    UP000075883    UP000000673    UP000075920    UP000075886    UP000075885    UP000076408    UP000075901    UP000078542    UP000075884    UP000007801    UP000008792    UP000075880    UP000069272    UP000075902    UP000076407    UP000075882    UP000007062    UP000075903    UP000075840    UP000005203    UP000242457    UP000030765    UP000002282    UP000000803    UP000008711    UP000001292    UP000092461    UP000215335    UP000192221    UP000268350    UP000015102    UP000001819    UP000008744    UP000007798    UP000007266    UP000092460    UP000092445    UP000092443    UP000075881    UP000078200    UP000092444    UP000054359   

PRIDE

H9IT07    H9J441    P20478    Q494K4    C8VV58    X2JDA5    + More

Pfam

PF00120   Gln-synt_C        + More
PF03951   Gln-synt_N
PF00307   CH

Interpro

IPR036651   Gln_synt_N        + More
IPR008146   Gln_synth_cat_dom       
IPR014746   Gln_synth/guanido_kin_cat_dom       
IPR027302   Gln_synth_N_conserv_site       
IPR008147   Gln_synt_b-grasp       
IPR027303   Gln_synth_gly_rich_site       
IPR001715   CH-domain       
IPR028433   Parvin       
IPR036872   CH_dom_sf       

SUPFAM

SSF54368   SSF54368        + More
SSF55931   SSF55931       
SSF47576   SSF47576       

Gene 3D

3.10.20.70     1.10.418.10    

ProteinModelPortal

H9IT07   A0A3S2PC21   A0A194Q394   A0A212EZP4   A0A194R0T4   A0A2H1VSF8   + More
A0A2H1W4Y2   A0A2W1BMY2   A0A2A4J4U6   I4DRB2   A0A0G3VIA2   I4DJ32   S4PCI7   E5L9K5   H9J441   A0A1J1HER3   A0A034VVT9   A0A0K8VEK6   A0A2L1DH34   A0A0K8VUW5   A0A034VRN0   A0A336LVS2   A0A0A1XT45   A0A0A1WVL5   W8BUA3   A0A1B6LQ28   B4JIW8   A0A182RCW5   A0A182MEI4   W5JBC9   A0A1W7RAF9   A0A182VQ96   A0A1B6LT02   A0A1Y1KMB3   A0A182Q4C3   A0A182PA28   A0A182Y797   A0A182SDE2   A0A195C1J9   A0A182N4N2   B3MVR3   A0A1Q3G582   B4MCX6   D0QWE3   A0A182JIW4   A0A0Q9VZ95   A0A1B6DBW2   A0A1L8E2I2   V9IDX6   T1E8G9   A0A182F8N6   A0A0G2QRP6   A0A2M4AWJ3   A0A182U6F2   A0A182XIC8   A0A182LFG0   Q7QBX9   A0A182V4E1   F5HK76   A0A182HTB3   A0A088A2A8   A0A2A3E9Y7   A0A084VJR5   B4PYB1   X2JJG8   P20478   B3NUD5   P20478-3   Q494K4   A0A0R1EIC3   B4IK13   A0A1B0CM38   C8VV58   X2JDA5   A0A232EN32   A0A0Q5T3A2   A0A1W4V0I0   A0A3B0JXI0   T1GZS8   A0A1I9WLM6   A0A2I9LP19   Q29H28   B4H0G6   B4N1T9   D6WFH1   A0A3B0JXJ2   M9V250   A0A1W4UNL4   A0A2L2Y3Q9   A0A1B0B749   A0A1B0AIW9   A0A1A9Y1D7   A0A182K3Y7   A0A1A9UHR5   V5G3M6   D3TPP6   A0A1B6IB03   A0A087UK01   J3JTU0   A0A0P5P3X2  

PDB

2D3C     E-value=3.16573e-18,     Score=218

KEGG

101735436    K01915 glutamine synthetase [EC:6.3.1.2] | (RefSeq) glutamine synthetase 2 cytoplasmic-like

PATHWAY

00220    Arginine biosynthesis - Bombyx mori (domestic silkworm)
00250    Alanine, aspartate and glutamate metabolism - Bombyx mori (domestic silkworm)
00630    Glyoxylate and dicarboxylate metabolism - Bombyx mori (domestic silkworm)
00910    Nitrogen metabolism - Bombyx mori (domestic silkworm)
01100    Metabolic pathways - Bombyx mori (domestic silkworm)
01230    Biosynthesis of amino acids - Bombyx mori (domestic silkworm)

GO

GO:0006542   GO:0004356   GO:0005524   GO:0005737   GO:0045213   GO:0007416   GO:0006538   GO:0031532   GO:0007155   GO:0003779   GO:0016021   GO:0006807   GO:0005886   GO:0003824   GO:0008237   GO:0008152   GO:0016491   GO:0015930  

PANTHER

PTHR12114  

Subcellular location

Cytoplasm  

Length:

134

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.0426100000000001

Exp number, first 60 AAs:

0.04246

Total prob of N-in:

0.22375

outside

1  -  134

 

 

Pi

167.060892

Theta

149.179834

Tajima's D

0.340918

CLR

0.002794

CSRT

0.465876706164692

Interpretation

Uncertain