Gene

KWMTBOMO13036

Pre Gene Modal

BGIBMGA000420

Annotation

PREDICTED:_serine/threonine_kinase_LKB1_isoform_X1_[Bombyx_mori]

Location

Bomo_Chr22(-):6937499-6950461      View in EpiBrowser

Location in the cell

Cytoplasmic   Reliability : 1.781 Nuclear   Reliability : 2.479

CDS

ATGGTTGGAAAGTATGTCATGGGTGATGTTTTAGGAGAAGGTTCATACGGAAAAGTCAAAGAAATGTTAGACTCGCAATCTTTATGTAGGCGAGCCGTAAAAATTCTTAAAAAGAGGAAATTAAGAAGAATACCAAATGGTGAACAAAATGTACAGAGAGAGATACAATTACTAAGAATCCTTAGACATAAAAATGTGATAGAACTAGTCGATGTTATCTATAATGATGAGAAACAAAAGATGTATCTTGTTATGGAATTCTGTGTTGGAGTATTACAGGACATGCTGGAGTCAAGTCCCGGTAAAAAGTTTCCTCAAAGACAAGCTCATGATTACTTTCTACAGCTGCTGGACGGATTAGATTACTTACATGGGCAGGGTGTTGTACATAAAGATATTAAACCAGGAAATTTACTTCTGACACTGGATCAAACTCTCAAAATCACAGATTTTGGTGTTGCTGAGGCATTAGACATGTTTTCACAGGAGGATATATGTTACACAGGACAGGGCTCACCTGCATTCCAGCCTCCAGAGATAGCCAATGGTGCTGAACAATTTTCTGGAACTAAAGTTGATATATGGAGCAGTGGAGTTACATTGTACAACATGACAACAGGGAGGTATCCGTTCGAGGGTGACAACGTGTACCGATTGCTGGAGGCGATAAGCCGGGGTCCCCCCGCGCCCCCGCCCGCGAGCGTGGGCCCCGCTCTCAGCGCTCTGCTCGTGCACATGCTCAACCGAGACCCTACACTAAGACCCACCGTCCACGAGATCAGGAGACACGCATGGGTGCAGGCAACACCGCCCTTCGAACCGGGCGAGAAACTAGTGAATCCGAGATCTCGACGTTCCGACGAGCTTCACACTTCGACTGTAATACCGTATCTCGTCGAGAGGCATTACGCTTCTGCGCAGGAATACTTCACCGAAAGGGACCTGCGGCAAGGGCTGGGTGACGGCGGCTCCCGGACGATGTCGACTGCGGAATTGTCTGACGGAGGATCGGGGCAGCACAAGAGGCGATGGCACTCGTCGTGCGGCCGGCTGCCCTCGTGCCGGCTCACGTGA

Protein

MVGKYVMGDVLGEGSYGKVKEMLDSQSLCRRAVKILKKRKLRRIPNGEQNVQREIQLLRILRHKNVIELVDVIYNDEKQKMYLVMEFCVGVLQDMLESSPGKKFPQRQAHDYFLQLLDGLDYLHGQGVVHKDIKPGNLLLTLDQTLKITDFGVAEALDMFSQEDICYTGQGSPAFQPPEIANGAEQFSGTKVDIWSSGVTLYNMTTGRYPFEGDNVYRLLEAISRGPPAPPPASVGPALSALLVHMLNRDPTLRPTVHEIRRHAWVQATPPFEPGEKLVNPRSRRSDELHTSTVIPYLVERHYASAQEYFTERDLRQGLGDGGSRTMSTAELSDGGSGQHKRRWHSSCGRLPSCRLT

Similarity

Belongs to the protein kinase superfamily.

Uniprot

A0A3S2NM10   A0A2A4J7X3   A0A2W1BVA9   A0A2H1VHV5   A0A194QW25   H9IT41   + More
A0A194PWS1   A0A212F481   A0A2J7QVW7   A0A158P322   E2AJH8   F4WM76   A0A067R0B3   A0A2P8Z3J3   A0A0A9XWP5   A0A1B0CEH8   A0A1B0DPW2   A0A2R7W989   A0A1W4WL10   A0A195BBZ2   A0A1W4WAY1   A0A026WAI1   A0A195DCC3   A0A151IGF1   A0A1Y1K0R7   A0A0P4VJT5   R4G8A9   T1HN05   A0A1B6L8B9   A0A1L8DKA3   K7J666   A0A088APS1   A0A232F6V5   A0A023F908   A0A069DTU5   A0A1B6EF04   A0A0V0GAQ1   A0A224XKD1   A0A0L7QQA4   A0A0L7L7A0   A0A0M9A2H1   E9IEY0   A0A2A3E500   A0A154PFV9   A0A0L0CEI5   A0A1I8NZ80   D6X0P9   A0A195F3K0   A0A0M4MF00   A0A1I8M4E4   T1PIL4   A0A1A9W605   A0A182JB42   A0A1B6HBW0   A0A182GXB7   D3TMT6   A0A1A9XJ21   A0A1B0BK01   A0A182QVN6   A0A182N4L3   A0A293M950   A0A293MY28   A0A182P579   A0A2J7QVW5   A0A182JQC8   A0A084WTF2   A0A1A9V749   A0A1A9Z488   A0A1B0FGP7   A0A2M4BIN5   A0A2M4BIM8   A0A182XE76   A0A182TTQ6   Q7QBI7   A0A182HJ47   A0A182RPM6   W5JFF4   A0A182FR88   A0A2S2QL85   A0A2M4CZ85   E0W1E5   B3LXA9   W8CAC6   B3P420   A0A182Y7B4   A0A0P8XX91   N6U5C4   B4PQH4   A0A1Q3FAE3   A0A1E1XF88   A0A1Q3FB09   B4M0X1   A0A1Q3F9U9   Q297P6   A0A1Q3FAZ8   A0A1W4V4U5   A0A2H8TMY0   Q178C1   B4G2U3  

Pubmed

28756777    26354079    19121390    22118469    21347285    20798317    + More
21719571    24845553    29403074    25401762    26823975    24508170    30249741    28004739    27129103    20075255    28648823    25474469    26334808    26227816    21282665    26108605    18362917    19820115    25315136    26483478    20353571    24438588    12364791    14747013    17210077    20920257    23761445    20566863    17994087    24495485    25244985    23537049    17550304    28503490    15632085    17510324   

EMBL

RSAL01000005    RVE54371.1    NWSH01002803    PCG67502.1    KZ149892    PZC79022.1    + More
ODYU01002641    SOQ40409.1    KQ461073    KPJ09738.1    BABH01013306    KQ459586    KPI97811.1    AGBW02010421    OWR48540.1    NEVH01009770    PNF32712.1    ADTU01001302    GL440027    EFN66373.1    GL888217    EGI64720.1    KK852801    KDR16301.1    PYGN01000212    PSN51071.1    GBHO01018387    GBRD01003536    GDHC01004496    JAG25217.1    JAG62285.1    JAQ14133.1    AJWK01008878    AJWK01008879    AJVK01018648    AJVK01018649    KK854482    PTY16253.1    KQ976522    KYM82081.1    KK107356    QOIP01000010    EZA52039.1    RLU17468.1    KQ980989    KYN10560.1    KQ977726    KYN00288.1    GEZM01101726    JAV52357.1    GDKW01002096    JAI54499.1    GAHY01001292    JAA76218.1    ACPB03015113    GEBQ01020014    JAT19963.1    GFDF01007191    JAV06893.1    NNAY01000881    OXU26087.1    GBBI01000765    JAC17947.1    GBGD01001549    JAC87340.1    GEDC01000808    JAS36490.1    GECL01001268    JAP04856.1    GFTR01006148    JAW10278.1    KQ414786    KOC60818.1    JTDY01002539    KOB71219.1    KQ435789    KOX74479.1    GL762728    EFZ20869.1    KZ288391    PBC26362.1    KQ434896    KZC10735.1    JRES01000501    KNC30670.1    KQ971371    EFA10720.1    KQ981855    KYN34757.1    KR075853    ALE20572.1    KA648611    AFP63240.1    GECU01035536    GECU01012394    JAS72170.1    JAS95312.1    JXUM01095090    JXUM01095091    JXUM01095092    KQ564172    KXJ72635.1    EZ422738    ADD19014.1    JXJN01015758    AXCN02000045    GFWV01012585    MAA37314.1    GFWV01021024    MAA45752.1    PNF32714.1    ATLV01026890    KE525420    KFB53496.1    CCAG010002945    GGFJ01003774    MBW52915.1    GGFJ01003775    MBW52916.1    AAAB01008879    EAA08443.5    APCN01002124    ADMH02001656    ETN61539.1    GGMS01009313    MBY78516.1    GGFL01006466    MBW70644.1    AAZO01007007    DS235870    EEB19451.1    CH902617    EDV41709.1    GAMC01005876    JAC00680.1    CH954181    EDV49194.1    KPU79306.1    APGK01041758    KB740997    KB632100    ENN75846.1    ERL88845.1    CM000160    EDW97270.1    KRK03614.1    KRK03615.1    GFDL01010567    JAV24478.1    GFAC01001283    JAT97905.1    GFDL01010357    JAV24688.1    CH940650    EDW67382.2    GFDL01010691    JAV24354.1    CM000070    EAL28159.2    GFDL01010346    JAV24699.1    GFXV01003680    MBW15485.1    CH477366    EAT42532.1    CH479179    EDW24138.1   

Proteomes

UP000283053    UP000218220    UP000053240    UP000005204    UP000053268    UP000007151    + More
UP000235965    UP000005205    UP000000311    UP000007755    UP000027135    UP000245037    UP000092461    UP000092462    UP000192223    UP000078540    UP000053097    UP000279307    UP000078492    UP000078542    UP000015103    UP000002358    UP000005203    UP000215335    UP000053825    UP000037510    UP000053105    UP000242457    UP000076502    UP000037069    UP000095300    UP000007266    UP000078541    UP000095301    UP000091820    UP000075880    UP000069940    UP000249989    UP000092443    UP000092460    UP000075886    UP000075884    UP000075885    UP000075881    UP000030765    UP000078200    UP000092445    UP000092444    UP000076407    UP000075902    UP000007062    UP000075840    UP000075900    UP000000673    UP000069272    UP000009046    UP000007801    UP000008711    UP000076408    UP000019118    UP000030742    UP000002282    UP000008792    UP000001819    UP000192221    UP000008820    UP000008744   

PRIDE

H9IT41   

Pfam

PF00069   Pkinase

Interpro

IPR039154   LKB1_c        + More
IPR008271   Ser/Thr_kinase_AS       
IPR017441   Protein_kinase_ATP_BS       
IPR000719   Prot_kinase_dom       
IPR011009   Kinase-like_dom_sf       

SUPFAM

SSF56112   SSF56112       

CDD

cd14119  STKc_LKB1

ProteinModelPortal

A0A3S2NM10   A0A2A4J7X3   A0A2W1BVA9   A0A2H1VHV5   A0A194QW25   H9IT41   + More
A0A194PWS1   A0A212F481   A0A2J7QVW7   A0A158P322   E2AJH8   F4WM76   A0A067R0B3   A0A2P8Z3J3   A0A0A9XWP5   A0A1B0CEH8   A0A1B0DPW2   A0A2R7W989   A0A1W4WL10   A0A195BBZ2   A0A1W4WAY1   A0A026WAI1   A0A195DCC3   A0A151IGF1   A0A1Y1K0R7   A0A0P4VJT5   R4G8A9   T1HN05   A0A1B6L8B9   A0A1L8DKA3   K7J666   A0A088APS1   A0A232F6V5   A0A023F908   A0A069DTU5   A0A1B6EF04   A0A0V0GAQ1   A0A224XKD1   A0A0L7QQA4   A0A0L7L7A0   A0A0M9A2H1   E9IEY0   A0A2A3E500   A0A154PFV9   A0A0L0CEI5   A0A1I8NZ80   D6X0P9   A0A195F3K0   A0A0M4MF00   A0A1I8M4E4   T1PIL4   A0A1A9W605   A0A182JB42   A0A1B6HBW0   A0A182GXB7   D3TMT6   A0A1A9XJ21   A0A1B0BK01   A0A182QVN6   A0A182N4L3   A0A293M950   A0A293MY28   A0A182P579   A0A2J7QVW5   A0A182JQC8   A0A084WTF2   A0A1A9V749   A0A1A9Z488   A0A1B0FGP7   A0A2M4BIN5   A0A2M4BIM8   A0A182XE76   A0A182TTQ6   Q7QBI7   A0A182HJ47   A0A182RPM6   W5JFF4   A0A182FR88   A0A2S2QL85   A0A2M4CZ85   E0W1E5   B3LXA9   W8CAC6   B3P420   A0A182Y7B4   A0A0P8XX91   N6U5C4   B4PQH4   A0A1Q3FAE3   A0A1E1XF88   A0A1Q3FB09   B4M0X1   A0A1Q3F9U9   Q297P6   A0A1Q3FAZ8   A0A1W4V4U5   A0A2H8TMY0   Q178C1   B4G2U3  

PDB

2WTK     E-value=1.00048e-96,     Score=902

KEGG

100145906    K07298 serine/threonine-protein kinase 11 [EC:2.7.11.1] | (RefSeq) Lkb1; serine/threonine kinase LKB

PATHWAY

04068    FoxO signaling pathway - Bombyx mori (domestic silkworm)
04140    Autophagy - animal - Bombyx mori (domestic silkworm)
04150    mTOR signaling pathway - Bombyx mori (domestic silkworm)

GO

GO:0004674   GO:0005524   GO:0030295   GO:0001558   GO:0030010   GO:0042593   GO:0004672   GO:0016021   GO:0006468   GO:0005737   GO:0005634   GO:0035556   GO:0042770   GO:0044773   GO:0072697   GO:0045451   GO:0005768   GO:0005938   GO:0046328   GO:0007052   GO:0018107   GO:0045201   GO:0016325   GO:0030709   GO:0043065   GO:0010897   GO:0007391   GO:0008340   GO:0043565   GO:0007155   GO:0005515   GO:0008237   GO:0008152   GO:0016491   GO:0015930  

Length:

357

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.00625

Exp number, first 60 AAs:

0

Total prob of N-in:

0.01461

outside

1  -  357

 

 

Pi

241.983344

Theta

162.615404

Tajima's D

1.223175

CLR

0.461557

CSRT

0.71896405179741

Interpretation

Uncertain